Our preprint about Neuroinflammation in #LongCovid is online! This group met during the community-driven event #UnitedtoFight last year. This publication in #NeuroCovid is just another example of how science works better when we listen to the community and work together with them! (1/3)

i love it!

Since this is going around again, figured I'd add the more hopeful addendum that encourages scientists to keep doing their important research and to speak out about the current attacks on US science. rdcu.be/emD0Z

🚨New in @cellpress.bsky.social We discovered that hippocampal replays in natural-scale environments are highly fragmented, not full-length. doi.org/10.1016/j.ce... 👇🧵

I just signed the Bethesda Declaration and urge you to do the same today, so that we all stand with NIH researchers as Battacharya appears before the Senate Appropriations Committee tomorrow.

Signed. Read and spread:

New Op-Ed in the Guardian regarding the new "Gold Standard Science" Executive Order. From @cdelawalla.bsky.social @carlbergstrom.com @briannosek.bsky.social @michaelemann.bsky.social, Carol Greider, and Victor Ambros. www.theguardian.com/commentisfre...

📌New bio constrained ANN learning rule: ➡️dendritic target propagation⬅️ considers cell diversity, compartmentalization, FF FB inputs, more. 🧠📈🤖🧪

7/7) As a final thought for funding, particularly for younger scientists, I am a strong advocate for the NSERC Discover Grant model: - Smaller grants, with high success rate (~50%) - Only one grant per lab - Young researchers do not have to hit the same bar as established researchers to be funded

👀Interesting take from @stephanie-theves.bsky.social linking general intelligence and abstraction. One to watch. 🧪🧠📈🧠🤖🧠👩‍🔬 _ ?(emoji analogies seemed fitting)

🚨New paper alert! 🚨 Inactivation of the nucleus reuniens causes relapse of extinguished fear. Here we show this “circuit-induced relapse” depends on hippocampal fear memories and is mediated by hippocampal engrams. Congrats to the team!

America cannot long remain free, nor first among nations, if it becomes the kind of place where universities are dismantled because they don't align politically with the current head of the government.

We agree. KenjiLee your data. @sabbaspoor.bsky.social's version uncovered surprisingly specific spike-field motifs and short latency spike timing interactions in macaque CA1: doi.org/10.1016/j.ce...

On behalf of Nicole Carr: new preprint from the Chand/Moore labs! High-resolution laminar recordings reveal structure-function relationships in monkey V1. 1/4 www.biorxiv.org/content/10.1...

As I try to wrap my head around my new field of affective science writ large and The Theory of Constructed Emotion specifically, @elisennesh.bsky.social has been helpful. For the many here who like to discuss "how we sciene", my sense is that TCE is a different approach than other ways.

"My instinctive reaction was to withhold this case from publication. The patient was my only sister." An incredible article (still guarded behind a paywall by Oxford University Press, 90 years after publication)

Do everyone a favor and read this. Then act. 🧠📈🧪

#preprint: We mapped the structure and function of olfactory bulb circuits with in vivo 2-photon microscopy and synchrotron #Xray holographic nanotomography. doi.org/10.1101/2025... @yuxinzhang.bsky.social @andreas-t-schaefer.bsky.social @apacureanu.bsky.social @crick.ac.uk @esrf.fr

👀Come for the 3D microscopy porn, stay for the ensemble coding principle. I will never not like the olfactory circuit organization. Here’s a punchline post in the thread:

Stimulating vosstacular stim work, and another case of targeting lateral temporal lobe (not medial) for stim in humans. ❓🙋🏻‍♀️ to Joel/Jim: you did parietal stim before, so would you pick LTL or Par. for therapeutic target to address “MTL”ish memory impairment? Or neither? 🧠 📈 🧪

In spiking neural networks, neurons communicate - as in the brain - via short electrical pulses⚡(spikes). But how can we formally quantify the (dis)advantages of using spikes? 🤔 In our new preprint, @pc-pet.bsky.social and I introduce the concept of "Causal Pieces" to approach this question!

Many processes from industry are not appropriate or overkill for an academic setting, but we can and should be doing better than we currently are. Our paper tries to give practical advice on how you can improve your scientific workflow, without being a coding guru. www.nature.com/articles/s44...

Nice approach to “what happens in the wake of a ripple?”

Yay, Canada! 🇨🇦🎉♥️ Elbows up and keep your science strong www.cbc.ca/news/politic...

'Exodus of the bright minds', my interview for @spiegel.de "The Trump administration is harassing science, cutting funding to universities, and intimidating researchers and students with expulsions. Four scientists share why they want to leave the country." #SpeakOut www.spiegel.de/wissenschaft...

One of the fun parts of this gatekeeping is the fact that we are actually trying to empirically and theoretically test some of the assumptions that could delineate between some of the thoughts that stand between ecological and classical representational "neuro"science without taking any sides.

I wrote something up for AI people who want to get into bluesky and either couldn't assemble an exciting feed or gave up doomscrolling when their Following feed switched to talking politics 24/7.

Did they really just go from freezing memories to frozen memories 🥶? @tjryan.bsky.social you need a trip to the tropics 🌴. Impressive study, broad implications for general physiology 🧪

One motivation I have heard to cut/destroy #NIH and biomedical research is that AI will just replace it. But that's folly. The people who say that can't have experience with real discovery science.

Leaner and meaner than a transformer? B/c #BTSP? Ok correlation-based cognitive map learner (CCML), you have my attention. 🧠📈🤖

3/5) The real mechanism for credibility in science is simply the test of time: Can someone reproduce the results? Do others build on the findings? Real rigour in science comes from waiting to see whether a result holds and leads to new results. Period - that's it. It's not peer review.

Rategory learning: antidromic systems consolidation. Not really, but it’s pithy. 🧠📈

Excited to announce the Madison Symposium on Memory and Control! postlab.psych.wisc.edu/msmc/: @paller.bsky.social, @karihoffman.bsky.social, Joel Voss, @charan-neuro.bsky.social , Thilo Womelsdorf, @earlkmiller.bsky.social . Best talk titles ever! (vote for your favorite here 🤗)

Love this. And meeting and talking alone is powerful. 'What made ["righteous gentiles"] courageously agree to hide Jews while the majority went along with tyranny[?] ... Turns out there was one circumstance that determined almost everything ... you had to be asked.' www.vox.com/future-perfe...

At least 28 Alzheimer's-related research projects, totaling $223.7 million, had been terminated by #NIH as of April 11. #Alzheimers #dementia #science #NeuroSky #GeriSky

Trump proposes massive NIH budget cut and reorganization www.science.org/content/arti...

Best takedown I've read on the war on science. It matters to make these points. I hope some affected editors-in-chief read this before making extremely consequential decisions next week.

🧠📈

Yup - or single-purpose/reductionist [models of] behaviors when the system must manage multiple goals IRL. If we race to the bottom with low-D tasks, should we then marvel at how scalar/categorical the response? elifesciences.org/articles/908...

Ok so yeah, this has quickly become the #1 misunderstanding about the canceled grants the grants are not “subsidies” or “entitlements” to Harvard or Princeton or whatever they aren’t going into universities’ endowments they are competitive contracts won by these universities to do research

🌎❤️‍🩹More US own-goals: undermining research by threatening int’l ties, from how we recruit the best students to procurement of specialized parts. This study was led by the gutsy, thoughtful @sabbaspoor.bsky.social using 🇬🇧 Cambridge Neurotech and 🇨🇦Brainsight/Rogue Rsh parts. In the before times.

Our new paper is out in Science. What is the synaptic plasticity rule in the brain, we asked. It turns out there are multiple, even within individual neurons. Congrats Jake! www.science.org/doi/10.1126/...

Multiple learning rules in different parts of dendrites. Definitive goodbye to hoping the brain is simple...?? 😯 www.science.org/doi/10.1126/...

Does your research involve comparing experimental conditions? Then our latest publication is for you: We developed generalized contrastive PCA (gcPCA), a tool for comparing high-dimensional datasets. 🧠📊 doi.org/10.1371/journal.pcbi.1012747 This tool was born out of necessity, here is the story. 🧵 1/

Explore top neuroscience meetings and events. Filter events by topic, and see upcoming webinars compiled by @worldwideneuro.bsky.social. Are you organizing a neuroscience conference? Share it with us at [email protected] #neuroskyence www.thetransmitter.org/events/?utm_...

I wrote a little digest + tribute to an article that shaped my career: Sadtler et al Neural constraints on learning! (and also managed to sneak in a shout out to another one) Read for free here: rdcu.be/eg5To Thanks to the editors for the invite and input!

Top-down feedback is ubiquitous in the brain and computationally distinct, but rarely modeled in deep neural networks. What happens when a DNN has biologically-inspired top-down feedback? 🧠📈 Our new paper explores this: elifesciences.org/reviewed-pre...

I joined this podcast to talk about sleep, dreams, and James Joyce. Yes, all in one conversation. It was a lot of fun! 🔊 Heads up: the audio is a bit rough at the start, but it clears up quickly. Listen here: podcasts.apple.com/ca/podcast/b...

Do you want to analyse multidimensional large scale foraging data? I have a postdoc opening. Postdoc will be part of an HSFP grant ‘”Neurometabolic mechanisms underlying social foraging” with Robert Froemke (NYU) and Jee Hyun Choi (KIST). Details: stellen.uni-konstanz.de/jobposting/8...

Yes!!! 👏