🎉 Our new #mirobiome paper in #JHEP is out! We found distinct gut #virome shifts in #ACLF - from virulent to temperate #phages - with Lactococcus A + Enterococcus B phages linked to infections & higher 90-day mortality 👉 Read more: www.sciencedirect.com/science/arti... 📽️Video: youtu.be/0YF6qToBQUM

🌍 The MICROB-PREDICT team met in Münster, Germany from 1–2 October for its 14th Steering Committee Meeting! 👉 Team leaders discussed results from 20 new papers about late-stage #LiverDisease #cirrhosis #biomarkers and IPR topics as the project nears its final phase. The finish line is in sight!

🚨 New #LiverFailure insights 🚨 In patients with #cirrhosis + acute #decompensation, secretory #IgA strongly correlates with #gut-barrier failure and is a powerful predictor of 90-day mortality in acute-on-chronic #LiverFailure #ACLF 👉 Watch on YouTube: youtu.be/KapUqG7AFFk #Biomarkers #GutBarrier

👏 ALB-TRIAL hits 50% enrollment 🎉 Half of the planned 240 patients have now been recruited across 14 centres in 7 countries - great progress for the MICROB-PREDICT project! Huge thanks to all site teams - Onward to full enrollment & better treatment for #cirrhosis patients with #ascites! #albumin

Join this exciting event! Don't miss our #OpenInnovation event, uniting experts in #DrugDevelopment, #bioinformatics, and #hepatology. Connect with researchers, industry professionals, and investors to share insights & explore collaboration opportunities! 🚀 Register now: inevent.uk/en/Crowdheli...

🧪 SAT-209 – #EASL2025 MNK6106 vs. rifaximin to treat #HepaticEncephalopathy - new Phase 2a data from Prof. @rajivjalan.bsky.social (UCL) explores safety, PK & ammonia-lowering potential. HE treatment innovation in motion! #Cirrhosis

🧠 SAT-210 – #EASL2025 New tool alert! The #mHEST scale brings clarity to grading hepatic #encephalopathy in trials & clinics. A big step for #cirrhosis care. Kudos to Prof. @rajivjalan.bsky.social & his team! #LiverHealth #HE #ClinicalResearch

🔬 Improving the prognostic performance of the #MELD score is a challenge that Nikolaj Torp (Odense University Hospital) took on, comparing the original score with MELD 3.0 in 777 patients with an acute #decompensation of #cirrhosis #POSTER SAT-196-YI 👏 📅 Presented at #EASLCongress | #EASL2025

✨ #PosterTour today at #EASLCongress 2025: All our 3 Horizon2020 #LiverResearch projects in 1 session! Topic: #Cirrhosis & #PortalHypertension Chair: Maria Papp 💡 Big moments: #AMMON-OHE model for post-#TIPS #encephalopathy (Rajiv Jalan) #Terlipressin response in AKI-HRS w/ CKD (Frank Uschner)

One last time #LIVE from the #EASLStudio: Tot Ziens Amsterdam, Hola Barcelona! 👋 As #EASL2025 draws to a close, Debbie Shawcross and Aleksander Krag reflect on the highlights from Amsterdam and set the stage for #EASL2026 in Barcelona. Thank you for an inspiring #EASLCongress - see you next year!

🧪 Mads Israelsen (Odense Universitetshospital – Svendborg Sygehus) leads together with Alberto Zanetto the YI #Workshop on How to prepare a #Clinical #Practice #Guideline in Hepatology, offering valuable insights for young investigators. 📅 Presented at the #EASLCongress | #EASL2025

One last time at #EASL2025: Wim Laleman (KUL) hosts the EASL/CIRSE Skills Learning Centre session on #Liver #Haemodynamics, providing hands-on learning in liver disease management. 🕙 10:15 – 11:15, Skills Learning Centre 2 @easlnews.bsky.social @cirsesociety.bsky.social

Live from the #EASLCongress: Debbie Shawcross (KCL) presents on Rebooting immunity: Harnessing FMT to revive innate defences in #cirrhosis as part of the Symposium “Microbiome and liver health: Unveiling new therapeutic pathways” 🦠🧫 #EASL2025 @easlnews.bsky.social @kingscollegelondon.bsky.social

Join us at the Industry Room: Evolving concepts in MASLD, ALD & MetALD at #EASLCongress Learn about: ✏️ New terminology & pathophysiology 🔬Non-invasive tools for diagnosis, prognosis & monitoring 🚨 Stay updated on the latest in metabolic & alcohol-related liver disease! #MASLD #MetALD

👏 What an accomplishment 🥳 Frederike Krus selected for this afternoon's #PosterTour at #EASLCongress 👉 POSTER ID FRI-175 Loss of hepatic #leptin clearance is associated with the development of #ACLF, acute-on-chronic #LiverFailure 📍 #Cirrhosis & Complications 📅 Fri, 9 May @medblab.bsky.social

Prof. JonelTrebicka presents and discusses the development and success of #TIPS over the past 25 years, high above the rooftops of #Amsterdam.

We are ready for #EASLCongress. We are happy to welcome you at our Posters.

Breaking Barriers 🩺: Novel insights in today's evening Abstract Session on #Alcohol 🍷 at #EASLCongress (Alcohol-related #LiverDisease), co-chaired by Elisa Pose from MICROB-PREDICT partner Fundació Clínic per a la Recerca Biomèdica, FCRB, in Barcelona. @easlnews.bsky.social @europeliver.bsky.social

🩺 #POSTER FRI-226 by Wenyi Gu (@medblab.bsky.social at the Universitätsklinikum Münster #UKM) presents her newest results on the burden & impact of #extrahepatic organ failures in European patients with #cirrhosis. 📅 Presented at #EASLCongress | #EASL2025, up until 17h, still time to swing by ☺️

🌟 Rising star - first big conference for him, so give him an applause 👏! Hendrik Rogge presents a great #poster today at #EASLCongress about the 📊 prediction of circulatory failure in intensive-care #patients with liver #cirrhosis & #ACLF. 👉 #POSTER FRI-182, up until 17h @medblab.bsky.social

🔬 Maximilian Brol's #POSTER FRI-493 👉 Conversion from standard-release to prolonged-release tacrolimus mitigates #calcineurin-induced #nephrotoxicity in patients after #LiverTransplantation The poster is still up until 17:00 today ☺️ 📅 Presented at #EASLCongress 2025 @medblab.bsky.social

🔬👩‍🔬 Big news: Loss of hepatic #leptin clearance is associated with the development of acute-on-chronic liver failure #ACLF #POSTER FRI-175 by Frederike Krus (Universität Münster, @medblab.bsky.social) - don’t miss it, up until 17h today! 📅 Presented at #EASLCongress 2025 #LiverFailure #cirrhosis

🎥 LIVE from the #EASLStudio at #EASL2025! @debbieshawcross.bsky.social (KCL) leads today’s deep dive into “Moving towards recompensation: Putting out the fire that fuels decompensation and ACLF” - tackling the key drivers of decompensation and ACLF, from systemic inflammation to portal hypertension.

Debbie Shawcross chairs Abstract Session 2 #GeneralHepatology about the hottest #hepatology research. Highlights: #CALIBRE trial, #fibrosis therapies & #PSC diagnostics. Congrats to Ajay Kumar Duseja & Annalisa Berzigotti on their awards! 🌟 The future of #hepatology looks bright 🌍💡 #EASLCongress

🔬 MICROB-PREDICT's Maja Thiele from Odense University Hospital chaired the well-attended early-morning session on the Future of #Hepatology today at #EASLCongress in sunny ☀️ Amsterdam 🌷 👉 Novel therapeutics & challenges in managing #MASLD (Metabolic dysfunction–associated steatotic liver disease)

📢 Join us at Track Hub 5 for the poster tour! #EASLcongress 🩺 An insightful poster tour session covering cutting-edge research on MASLD, MDR in cirrhosis, chronic hepatitis B, MetALD, Budd-Chiari syndrome, and more! Impressive work by young investigators, science in action!

No time to visit the Skills Learning Centre yesterday? 🫣 No problem - join Wim Laleman today at 10h, 14h or 16:15h for is in-depth session on #Liver #Haemodynamics! 💡 #Today at #EASLCongress #EASL2025 @easlnews.bsky.social @cirsesociety.bsky.social

🚨 #LIVE from #EASLCongress Elisa Pose (FCRB) & Alexandre Louvet are chairing the EASL/SALVE Symposium: Controversies in the management of patients with #alcohol #use #disorder. Join in to discuss key challenges and emerging strategies in care! 🕣 08:30 – 09:45, Erlinger Room @easlnews.bsky.social

📊 Prognosis of primary sclerosing cholangitis (#PSC) in #Hungary 🇭🇺 is independent of coexisting inflammatory bowel disease (#IBD), and the prognostic ability of the currently used PSC risk scores are limited. #POSTER THU-367 by David Tornai (UNIDEB) 📅 Presented at #EASLCongress | #EASL2025

📚 Learning from the best at the EASL Congress: Maja Thiele (OUH) discusses Alcohol-related liver disease as part of The JHEP Reports Symposium: Keys to get your manuscript accepted. 💡 #EASL2025

🐭 Blockage of microfibrillar-associated protein 4 (MFAP4) decreases liver fibrosis in two murine models of steatotic liver disease #POSTER THU-058-YI by Maximilian Brol (UM) presents preclinical data showing that blocking MFAP4 reduces #liver #fibrosis in two murine models. #EASL2025

🧪 Live from #EASLCongress In the Meet-the-Experts session, Maja Thiele (OUH 🇩🇰) shares insights on 🧫🔬👩‍🔬 Cutting-edge strategies for #biomarker discovery in #hepatology - from innovation to clinical application to help liver patients 📅 Presented at #EASL2025 🕑 14:00 – 15:00 h @easlnews.bsky.social

Don’t miss this #poster: 🔬 Sex-specific #estradiol signalling in liver #cirrhosis: THU-149-YI Fabian Schachteli (@medblab.bsky.social) investigated the role of sex-specific estradiol signalling in the pathophysiology of liver cirrhosis and portal hypertension. #EASLCongress #EASL2025

🤩 Full house at General Session 1 today 🥳 Abstract Session “General #Hepatology”, chaired by Aleksander Krag from Odense University Hospital in Denmark 🇩🇰, featuring a broad range of cutting-edge #LiverResearch 🔬. 📅 Presented at #EASLCongress | #EASL2025 🕥 10:30 – 12:30 h @easlnews.bsky.social

🔬 Live from #EASLCongress 👉 Jonel Trebicka @medblab.bsky.social presents as panelist in the session “From Covered #TIPS to TIPS using Controlled Expansion" in Ring-Larsen Room. 💡 An insightful discussion on the latest advancements in TIPS technology for managing #cirrhosis complications 👏

Aleksander Krag (OUH) in General Session 1, an abstract session under the topic General Hepatology, featuring a broad range of cutting-edge research. 📅 Presented at the #EASLCongress | #EASL2025 🕥 10:30 – 12:30, De Groote Room

Prof Jonel Trebicka speaks about the evolution of #TIPS at #EASLCongress. #GoreMedical

🔬 EASL/CIRSE Skills Learning Centre: Liver Haemodynamics Join Wim Laleman (KUL) for an in-depth session on Liver Haemodynamics 📅 Presented at the #EASLCongress | #EASL2025 🕙 10:00 – 11:00 Also available at 12:30, 14:00, and 16:15! @easlnews.bsky.social @cirsesociety.bsky.social

👏 MICROB-PREDICT members Minneke Coenraad, Aleksander Krag and Debbie Shawcross were at center-stage at the #EASLStudio Opening Session for #EASLCongress on Wednesday speaking about hot topics and what not to miss this year! 🔥 #cirrhosis #ACLF #microbiome #Horizon2020 @easlnews.bsky.social

🌍 Equity in liver care starts with #listening👂. At the #Patient & Advocate Forum during #EASL2025, Minneke Coenraad (LUMC) opened with a powerful message on addressing #healthcare #disparities in the Netherlands 🇳🇱. 👏 A timely reminder that innovation isn't only scientific - it's also social. 🥰

👏 Two great #EASLCongress posters today were taking a closer look at the model of end-stage liver disease #MELD: 1️⃣ WED-239 by Nikolaj Torp (OUH) on the 📊 prognostic performance of MELD variants and the CLIF-C #AcuteDecompensation (AD) score in a cohort of 958 patients with #cirrhosis and #ascites.

More on #PortalHypertension: 💡 TIPS for hydropic decompensation improves short-term outcome: a case-control study #poster WED-186 by Eduardo Cervantes-Alvarez (@medblab.bsky.social), presented clinical data on the role of #TIPS in managing hydropic #decompensation of liver #cirrhosis. #EASL2025

At poster WED-503 Dominik Lüttgen presents a clinical decision tree for non-invasive diagnosis of #steatosis at #EASLCongress.

🤝 We’re live at the EF CLIF Networking Session at #EASL2025! Partners and collaborators are gathering to exchange insights on cirrhosis and its complications, building bridges between research and clinical innovation. 📍 Cirrhosis & Complications Track Hub @easlnews.bsky.social

🩺 TIPS for portal hypertensive gastropathy (PHD) bleeding reduces further #decompensation & mortality #POSTER WED-258 by Zeyu Wang presented clinical findings on the use of #TIPS to manage PHG bleeding, showing reduced rates of further decompensation & mortality. #EASL2025 @medblab.bsky.social

Sun is out for MICROB-PREDICT's ALB Trial Meeting #EASL2025! 🌞 Jonel Trebicka & Nikolaj Torp are joined by investigators and consortium partners to evaluate progress and coordinate next steps for our interventional study targeting acute decompensation in cirrhosis. @medblab.bsky.social

We were diving even deeper into today’s #MICROBPREDICT Networking Session at #EASL2025! 🦠🧬💉 From virome insights to gut-barrier mechanisms and the ALB-Trial - Brol, Tornai & Torp present key MICROB-PREDICT findings driving innovation in cirrhosis research. @medblab.bsky.social

We’re kicking off the MICROB-PREDICT Networking Session at #EASL2025! Prof. Dr. Jonel Trebicka @medblab.bsky.social starts with an overview: our mission to identify microbiome-based biomarkers and mechanisms that can predict, where the body can no longer compensate for liver dysfunction.

🩺 Shifting etiologies and emerging metabolic factors of hepatocellular #carcinoma from 2005 to 2020: a German nationwide population-based study Check out #POSTER WED-118-YI by Josune Cabello Calleja, exploring 15 years of nationwide data on evolving HCC #RiskFactors. #EASL2025 @medblab.bsky.social

🤩 We are already in full #EASLCongress swing 🤩 here in Amsterdam, gearing up for 👉 the MICROB-PREDICT #NetworkingSession at the Cirrhosis & Complications Track Hub 4 at 14:00 👉 the simultaneous A-TANGO #PatientEvent from 14:00-15:00, Room D202 (level 2, Elicium Building) @easlnews.bsky.social