hi

Party like it’s 2021.

@elsabirch.bsky.social and I had a great time at the @glasscannonnetwork.bsky.social retreat and got to play @deltagreen.bsky.social with @sydneygayle.bsky.social which was a lot of fun. If you are interested in TTRPGing, check out some of GCN’s great content. @chaosium.bsky.social

The US needs to be making its own medicines, especially for the new generation of personalized medicines (genomic, cell therapies, etc). We believe AI/automation is how that will happen. 🇺🇸💊 @wsj.com www.wsj.com/articles/u-s...

A great read!

👇 This is my political stance too

Part way through this fascinating book. www.amazon.com/gp/aw/d/B07B...

Based on the replies l, it looks like there a lot of fed workers on @bsky.app I just wanted to say THANK YOU. I can't imagine the shit you are going through right now Thanks for your service to our country

There are so many ways to rev up our immune response against cancer. Here, the oncolytic viruses www.cell.com/cancer-cell/...

Gather Health's mission to improve healthcare for older Americans. www.forbes.com/sites/amyfel...

This is exactly what happened to me, except that my story ends with a near death experience and an emergency D&C after transfusion. Pregnant women in Texas are in danger. And I worry most about Black women who experience medical racism. www.propublica.org/article/pors...

For Beginning Readers

HTS in vivo with barcoded genomic medicines is now a standard technique, but it's cool to see that approach applied to antibodies. www.pnas.org/doi/10.1073/...

Got a cool book on Die Brücke artist Kirchner. He was a leader of German Expressionism in the first two decades of the 20th century with a somewhat haunting style of rendering the figure.

Cephalopod craziness petapixel.com/2025/03/11/g...

His arrest and attempted deportation seem very much like a writ of attainder to me. The President can pardon federal crimes, but not convict them.

There is the important element that the jobs DOGE is cutting are US jobs, including a lot of veterans who live in states who voted for Trump.

It just keeps getting worse

In fact the opposite has generally been the case: we discover insight into micro-level phenomena as a result of developing accurate meso-scale theories. Thermodynamics came before statistical mechanics and served as the key constraint on it. ...

Interesting to see which countries drink the most coffee. www.statista.com/chart/8602/t...

Extending dog lifespan. @loyalfordogs www.washingtonpost.com/technology/2...

For those with a medical background, I think learning startup related finance is no harder, and with a lot of overlap, to learning how to manage ins and outs and electrolytes.

SRE’s may have more in common with emergency room physicians in things like personality and hobbies than I would have at first considered.

Calling yourself a king doesnt make you a king. Delivering an all-time banger of a speech on St. Crispin’s Day does.

Back on the other website I made a whole thread on the size of ocean animals in relation to Bernie Sanders. These crabs are so much bigger than people realize

The one thing I like about his stated goals is the focus on general wellness: nutrition and fitness. The approach to infectious disease is terrifying.

Pretty neat study, raises the possibility of a blood test for postpartum depression and some new potential pharmacological approaches to treat. www.nature.com/articles/s41...

One thing I never understand is all the criticism of the USFDA and their regulatory science. It’s the most data driven government organization in the world, willing to quickly change its mind with new data. It’s not perfect of course, but it’s regulation by rationality not emotion, very rare.

Investment in basic research has been one of the main pillars of economic growth in the US. Discovery combined with the free market system that can turn those innovations into scalable/distributable new products & services improves quality of life, and wealth in a non zero-sum way.

Great article. www.nature.com/articles/s44...

Our new piece in The Lancet on the potential of AI agents in medicine www.thelancet.com/journals/lan... @jameszou.bsky.social

The story behind RFK Jr. in Samoa's measles crisis has never been reported. He wasn't there to spread misinformation about vaccines (though he did). He wanted to study a "natural experiment" of unvaccinated kids. “I can’t imagine anything less ethical or more cruel.” www.nbcnews.com/news/us-news...

Does our country owe its existence to inoculation (the precursor to vaccination)? Historians seem to think so, in that George Washington's controversial decision to inoculate the Continental Army against smallpox seems to have saved the Army from destruction. www.battlefields.org/learn/articl...

Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X https://go.nature.com/42tH8Ai

Vincent Price's dramatic soufflé

Congrats to Tim Sweeney and the whole Inflammatix team! They are going to save many lives! www.prnewswire.com/news-release...

Enjoying this book about the Iroquois (Haudenosaunee) nations playing off relationships between the English/French/Dutch and other indigenous peoples. www.amazon.com/gp/aw/d/0670...

I have a Curta II, and a Curta I will be arriving in the post shortly. Love this piece of engineering.

Well, JP Morgan SF Healthcare week is over. It’s Friday night, so I am pounding some shots, #PauHana. FWIW, I tried to fist bump instead of shaking hundreds of hands, washed my hands a lot, etc, but I still got got.

One sign of the low-trust society is that incurious people believe they've been lied to rather than just didn't know perfectly knowable stuff.

When I prepare green tea (sencha or matcha) at home, I like it actually be green, basically so it looks like Ecto Cooler, which means the catechins and other key compounds in it have not oxidized. Here is how I do this…

Political polling works like this…

Reposting this guide from twitter because I COOKED here. (and still refer to this at work even now!)

"When Mexico sends its people, they're sending their best. They're sending firefighters to help solve American problems. They're bringing fire fighting uniforms. They're bringing fire fighting equipment. They're bringing kittens down from trees. And all, I assume, are good people."

My favorite piece of content this Sunday morning:

Galen Buckwalter, 68, shared with me his harrowing tale of being forced to flee the Eaton fire alone on his wheelchair through dark streets and fierce winds, dodging debris as fire neared his home. “In emergencies, disabled people are the last to get services…We have no system. You’re on your own”

That's a wrap on the conference coordination with @alexmorgan.bsky.social for this round of @pacsym.bio #psb25

I am very much enjoying the new book, Convential Boy, by @cstross.wandering.shop.ap.brid.gy. Wonderfully referential to recent books in the series through an in fiction TTRPG. torpublishinggroup.com/a-convention...

Great talk by @suinlee.bsky.social at @pacsym.bio #psb25 on interpretability approaches for AI systems in radiology, and generally the process/approach to quality/reliability assurance for healthcare system AI robustness and generalizability. paperswithcode.com/method/shap

Features of Adulthood xkcd.com/3034