Spatial and molecular insights into microglial roles in cerebellar aging https://www.biorxiv.org/content/10.1101/2025.03.01.640978v1

Spatial and molecular insights into microglial roles in cerebellar aging https://www.biorxiv.org/content/10.1101/2025.03.01.640978v1

Simultaneous analysis of single-cell gene expression and morphology provides new insight into how microglia change with age https://www.biorxiv.org/content/10.1101/2025.02.28.640888v1

Simultaneous analysis of single-cell gene expression and morphology provides new insight into how microglia change with age https://www.biorxiv.org/content/10.1101/2025.02.28.640888v1

Excited to share this collaborative work led by Guosong Hong’s group @stanfordneuro.bsky.social. A new method to render animals optically transparent for deep tissue imaging across the visible spectrum 🌈 www.biorxiv.org/content/10.1...

Slippery proteins in the brain’s blood vessels (vascular glycocalyx) form a protective barrier that breaks break down with age @carolynbertozzi.bskyverified.social #wysscoray @sophiamshi.bsky.social @nature.com www.nature.com/articles/d41... www.nature.com/articles/s41...

Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease www.nature.com/articles/s41...

Excited to be part of the work-"A high-throughput assay platform to discover small molecule activators of the phospholipase PLCG2 to treat Alzheimer’s disease"- now out in JBC ! Huge thanks to Qisheng and the team for this amazing collaborators! www.jbc.org/article/S002...

Microglia stuffed with fat struggle. Knocking out a lipid-droplet regulator in them boosted their appetite for Aβ and tempered plaque load. www.alzforum.org/news/researc...

Interested in brain aging? We are super excited to share our new review!! "Brain aging and rejuvenation at single-cell resolution" 🧪🧠 Massive CONGRATS to Eric Sun, Rahul Nagvekar, and Angie Pogson, three phenomenal graduate students in the lab!! authors.elsevier.com/sd/article/S...

Updated Aging Starter Packs to find people and labs who work on aging!! Aging Starter Pack 1 (already reached the maximum number!): go.bsky.app/5UXXaDA Aging Starter Pack 2 (can still add!): go.bsky.app/RfFYndJ Let me know if you'd like to be added! 😀

💘 Celebrate Valentine’s Day with cutting-edge science on APOE and lipid droplets! Join the ImmunityPIA webinar on 2/14/2025! 🎤 Speakers: @cohenlaboratory.bsky.social Dr. Xu Chen 🌟 Panelists: Dr. Kimberley Bruce Dr. Lance Johnson 👉 Register now: alz-org.zoom.us/webinar/regi... Don’t miss it!