Happy to share that our latest pre-print is out!!

This time we went “functional.” 🙂 After years studying pathological amyloids, we followed RIPK1/3 into the other side of aggregation - where amyloids help cells decide when to die. 🔗🔗 🔗 www.biorxiv.org/content/10.6...

We are looking for a PhD student in (mostly )wet-lab biochemistry to work on short linear motifs, intrinsically disordered regions, in the context of the Marie Curie network "IDPro". More info an apply here: www.uu.se/en/about-uu/...

Solving the many mysteries of amyloids 🧩🧬, next up at #VariantEffect25: @marianomartin.bsky.social from @bennibolo.bsky.social Lab presents: Deep mutagenesis reveals the interplay between RIPKs amyloid nucleation and protein activity

@marianomartin.bsky.social at #VariantEffect25

VSS people are always hungry for more heatmaps discussion! (and burgers!) #VariantEffect25

The first poster session just started! #VariantEffect25

Good morning #VariantEffect25! Kicking things off we have Mafalda Dias, @bennibolo.bsky.social @muffley.bsky.social welcoming us to this 8th annual symposium. We have 250 in-person participants, 60 people online, from 20 countries!

@marianomartin.bsky.social discussing amyloid formation from random sequence extensions at our first CNS 🧠network event @ibecbarcelona.eu Find out more this week on @pnas.org! www.pnas.org/doi/10.1073/...

Proud to be part of this big collaborative effort! We studied MCT8 deficiency via genomic, functional & deep learning integration. 🔗 www.nature.com/articles/s41...

Excited to share our latest in @SciAdvances! 🔍 We quantified ~100k sequences to train CANYA, an interpretable deep learning model for predicting amyloid formation. 🔗 www.science.org/doi/10.1126/...

Our new paper is out in PNAS! 🧪 We used deep mutational scanning & random extensions to uncover how Bri2 becomes amyloidogenic upon C-terminal extension. 🔗 www.pnas.org/doi/10.1073/...

🗓️ Mark your calendars! This is one not to miss! www.varianteffect.org/seminar-series

Countdown has started! Excited to welcome you in Barcelona for the 8th Mutational Scanning Symposium #VariantEffect25 🌍 @ibecbarcelona.eu @crg.eu @varianteffect.bsky.social events.ibecbarcelona.eu/mutational-s...