Miguel Correa
@m-correa-m.bsky.social
📤 279
📥 664
📝 25
Computational biologist @ Roche | Views my own
reposted by
Miguel Correa
Mohammed AlQuraishi
14 days ago
OpenFold3-preview (OF3p) is out: a sneak peek of our AF3-based structure prediction model. Our aim for OF3 is full AF3-parity for every modality. We now believe we have a clear path towards this goal and are releasing OF3p to enable building in the OF3 ecosystem. More👇
1
125
45
reposted by
Miguel Correa
Tanja Stadler
17 days ago
Open position at the Swiss Institute of Bioinformatics: We are looking for a Director of the Center of Pathogen Bioinformatics
apply.refline.ch/499599/0346/...
I am in the Center's steering board together with fantastic colleagues (Emma Hodcroft
@firefoxx66.bsky.social
, Richard Neher
@neher.io
, and
loading . . .
Director, Center for Pathogen Bioinformatics
The Centre for Pathogen Bioinformatics (CPB) is a unit of SIB which offers expertise and services in pathogen bioinformatics, computational molecular epidemiology and related multi-site project manage...
https://apply.refline.ch/499599/0346/pub/2/index.html
1
20
34
Hot off the press! Our paper, “Global comparative structural analysis of responses to protein phosphorylation”, is now out in Nature Communications!
www.nature.com/articles/s41...
loading . . .
Global comparative structural analysis of responses to protein phosphorylation - Nature Communications
Phosphorylation is central to protein regulation, yet its structural mechanisms remain poorly understood. Here, the authors conduct a global, systematic analysis of phosphorylated versus non-phosphory...
https://www.nature.com/articles/s41467-025-64116-4
16 days ago
1
43
13
reposted by
Miguel Correa
Nisha Hemandhar
3 months ago
Excited to share my PhD research, now on bioRxiv! We report a proteo-transcriptomic reprogramming and resource reallocation in the aging brain. Co–first author with Verena Kluever. Grateful to
@forna.bsky.social
for mentorship, and to
@tatjanat.bsky.social
, Carlos López Otín & all collaborators🧠
2
8
5
Today in predatory journal spam: plagiarizing 15% of your manuscript is OK
6 months ago
0
0
0
Good to know our paper on the protein-protein interaction network between phytoplasma effectors and host proteins is getting attention: it's a
#TopViewedArticle
in TPJ
@theplantjournal.bsky.social
onlinelibrary.wiley.com/doi/full/10....
loading . . .
Protein interaction mapping reveals widespread targeting of development‐related host transcription factors by phytoplasma effectors
This work shows that the effectors of phytoplasma, a globally economically important bacterial plant pathogen, have pervasive interactions with development-related host transcription factors, providi...
https://onlinelibrary.wiley.com/doi/full/10.1111/tpj.16546
7 months ago
0
2
0
reposted by
Miguel Correa
Sergey Ovchinnikov
7 months ago
If anyone has any tips for fellowships or grants or giftfunds our group can apply for (in the US), please send our way. So far, we've not had much luck in raising funds... 💰 In this relatively popular area, so I feel like I'm doing something wrong 😅
5
25
10
reposted by
Miguel Correa
Kevin K. Yang 楊凱筌
9 months ago
A protein language model trained to predict subcellular localization for human proteins can generate de novo sequences with the desired localization and identify pathological mutations.
@itamarchinn.bsky.social
@pgmikhael.bsky.social
www.science.org/doi/10.1126/...
2
93
19
reposted by
Miguel Correa
Andre Faure
10 months ago
At ALLOX
@alloxbio.bsky.social
in Barcelona we now have 3 computational positions available! 📌Structural Bioinformatics Scientist 👉
tinyurl.com/3rs46j4t
📌Platform Bioinformatician 👉
tinyurl.com/nyvazbke
📌Computational Chemist 👉
tinyurl.com/5n6vpem3
Apply or repost to help us spread the word 🙏
2
24
23
reposted by
Miguel Correa
Ylva Ivarsson
10 months ago
Looking forward to the monthly on-line seminars organized by the Protein Modules Community
@pmc-modularity.bsky.social
and talks on SLiMs, systems biology, signaling, computational biology and much more. First talks by Dr Gogl
@teamgogl.bsky.social
and Dr Dionne
@gingraslab.bsky.social
.
add a skeleton here at some point
0
16
10
reposted by
Miguel Correa
Marc Robinson-Rechavi
10 months ago
Long Covid: The never-ending pandemic in the magazine of
@snsf-ch.bsky.social
www.horizons-mag.ch/2024/12/02/t...
loading . . .
The never-ending pandemic
Horizons - Issue 143
https://www.horizons-mag.ch/2024/12/02/the-never-ending-pandemic/
1
7
2
reposted by
Miguel Correa
Nature Biotechnology
10 months ago
Deep learning methods aid in de novo design of proteins to neutralize lethal snake venom toxins in vitro and protect mice from a lethal neurotoxin challenge.
www.nature.com/articles/s41...
#NBThighlight
loading . . .
De novo designed proteins neutralize lethal snake venom toxins - Nature
Deep learning methods have been used to design proteins that can neutralize the effects of three-finger toxins found in snake venom, which could lead to the development of safer and more accessible an...
https://www.nature.com/articles/s41586-024-08393-x
1
32
11
reposted by
Miguel Correa
Venki Murthy
10 months ago
The Nobel Prize-winning chemist, Martin Karplus, has passed away. A pioneer in the theory and computation of the dynamics of macromolecules. 🧪
#ChemSky
0
76
25
reposted by
Miguel Correa
Stephanie Wankowicz
11 months ago
Are PDB models biased in terms of how well they explain the underlying experimental data and are modeled?
www.biorxiv.org/content/10.1...
loading . . .
Modeling Bias Toward Binding Sites in PDB Structural Models
The protein data bank (PDB) is one of the richest databases in biology. The structural models deposited have provided insights into protein folds, relationships to evolution, energy functions of struc...
https://www.biorxiv.org/content/10.1101/2024.12.14.628518v1
1
43
18
reposted by
Miguel Correa
Jean-Philip Piquemal
12 months ago
#compchem
Good read: Allosteric Communication Mediated by Protein Contact Clusters: A Dynamical Model
#compchemsky
pubs.acs.org/doi/10.1021/...
loading . . .
Allosteric Communication Mediated by Protein Contact Clusters: A Dynamical Model
Describing the puzzling phenomenon of long-range communication between distant protein sites, allostery is of paramount importance in biomolecular regulation and signal transduction. It is commonly as...
https://pubs.acs.org/doi/10.1021/acs.jctc.4c01188
1
11
2
So many easy choices, but I'll go for this
add a skeleton here at some point
11 months ago
0
3
0
reposted by
Miguel Correa
Bird account
12 months ago
How much of computational biology is doing detective work trying to figure out why some program won't run?
5
45
6
For those around Zurich, I'll be at the Zurich Seminar in
#Bioinformatics
this Thursday to talk about my work on the impact of phosphorylation on protein structure:
compbiozurich.org/news/2024/20...
loading . . .
Global comparative structural analysis of responses to protein phosphorylation<br/>Miguel Correa, FGCZ - CompbioZurich
Zurich Seminars in Bioinformatics
https://compbiozurich.org/news/2024/2024-12-05-zh-seminars-in-bioinformatics/
11 months ago
1
2
3
reposted by
Miguel Correa
Daniel Probst
11 months ago
Here's a first: I'm hiring a PhD student. If you have (or know someone who has) a strong background and interest in computational (bio)chemistry or computer science (especially 3D computer vision), let's work together 😊
www.wur.nl/nl/vacature/...
loading . . .
PhD student - Machine learning in bio- and cheminformatics
https://www.wur.nl/nl/vacature/phd-student-machine-learning-in-bio-and-cheminformatics.htm
0
43
23
Dear hivemind, in the absence of a fresh CAFA publication: what predictor(s) do people consider to be the state-of-the-art in protein function prediction nowadays?
#bioinformatics
#bioml
#protein
11 months ago
0
2
2
reposted by
Miguel Correa
Torsten Schwede
11 months ago
Assessors’ conclusions of the 3D category (individual protein chains) of
#CASP16
🧪
0
25
11
reposted by
Miguel Correa
Arne Elofsson
12 months ago
#CASP16
program is posted (so you can guess the "winners". Congratulations to Yang and Kihara who seems to have done well in RNA+Proteins. Also congratulations to AF3-server (i.e. me) who was selected to talk (i.e. most people did worse than the server).
predictioncenter.org/casp16/doc/C...
.
loading . . .
https://predictioncenter.org/casp16/doc/CASP16_Meeting_Program.pdf
2
41
19
you reached the end!!
feeds!
log in