Karen Dixon
@dixon-lab.bsky.social
📤 95
📥 108
📝 1
Cancer Immunology Lab in Basel 🇨đź‡.
reposted by
Karen Dixon
Seth Thomas Scanlon
5 months ago
@dixon-lab.bsky.social
, Gonzalo Fernandez Lahore, &
@kuchroolab.bsky.social
discuss the emerging roles for
#TIM3
in regulating
#MyeloidCell
#immune
responses!
loading . . .
Beyond T cell exhaustion: TIM-3 regulation of myeloid cells
We provide a comprehensive review of 20 years of research on TIM-3 functions in myeloid cells and T cell exhaustion.
https://www.science.org/doi/10.1126/sciimmunol.adf2223
1
10
4
Tremendously honoured to be recognised by the AACR among these fantastic scientists - Can't wait to hear more about the phenomenal work is doing!
#AACR25
@theaacr.bsky.social
add a skeleton here at some point
6 months ago
0
6
0
reposted by
Karen Dixon
Ayshwarya Subramanian
6 months ago
Grateful to share our study on the potential for immune checkpoint blockade in late-onset
#AlzheimersDisease
out
@nature.com
today. Co-led with Kimi, Zhuoran, Ahad
@kuchroolab.bsky.social
in a big team effort
@genelayinstitute.bsky.social
@broadinstitute.org
@harvardmed.bsky.social
 /1
loading . . .
Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease - Nature
The immune-checkpoint molecule TIM-3 regulates microglial homeostasis, and its microglial-specific deletion reduced cognitive impairment in a mouse model of Alzheimer’s disease.
https://www.nature.com/articles/s41586-025-08852-z
1
18
6
reposted by
Karen Dixon
Jeremy Borniger
7 months ago
academic.oup.com/sleep/advanc...
excited to share our lab’s first data paper, led by stellar lab tech Leah Boyd in a fun collab with
@erinmgibson.bsky.social
:) one step closer to understanding and combating chemotherapy-associated behavioral comorbidities.
loading . . .
Enduring NREM sleep fragmentation following methotrexate chemotherapy in cancer-naĂŻve mice
AbstractStudy objectives. Sleep disruption is common in people with cancer and survivors, but understanding the mechanisms driving these problems is diffic
https://academic.oup.com/sleep/advance-article-abstract/doi/10.1093/sleep/zsaf073/8087986
1
9
2
reposted by
Karen Dixon
Erin Gibson
7 months ago
A great collab with
@jborniger.bsky.social
lab showing persistent NREM sleep disturbances with chemotherapy exposure irrespective of cancer presence. Important work in our understanding of how cancer treatments can impart lasting neurological changes.
add a skeleton here at some point
0
8
1
reposted by
Karen Dixon
Michelle Monje
8 months ago
Delighted to share the published version of this work from brilliant
#CancerNeuroscience
post-doc Tara Barron detailing GABAergic neuron-to-glioma synapses in
#DIPG/#DMG
. đź§µ Open access link:
www.nature.com/articles/s41...
2
75
23
reposted by
Karen Dixon
Toni Choueiri, MD
8 months ago
Our paper in
@nature.com
is finally published: a prospective trial of a personalized Neoantigen Vaccine in Kidney Cancer
www.nature.com/articles/s41...
This is teamwork with
@danafarber.bsky.social
@yalecancer.bsky.social
@harvardmed.bsky.social
+ Wu lab
www.nature.com/articles/s41...
1
28
16
reposted by
Karen Dixon
Scheff Research Lab
8 months ago
📢New publication out: Sensory Neurotransmission and Pain in Solid Tumor Progression! This review article by first author
@andremartel.bsky.social
details recent work on the bidirectional relationship between sensory neurons and
#cancer
cells.
authors.elsevier.com/sd/article/S...
#neurobiology
1
6
3
you reached the end!!
feeds!
log in