Dr Dorota SK
@drdorotask.bsky.social
📤 751
📥 187
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Aging Eye laboratory.
https://faculty.sites.uci.edu/skowronska-krawczyk/
Our lab is
#hiring
! Interested in
#biologyofaging
,
#aging
,
#lipids
,
#AMD
,
#glaucoma
,
#NGS
,
#singlecell
and in general molecular biology? Apply TODAY!!!! Indicate your interest in aging biology!!! Deadline for application to my lab - end of 2025!
recruit.ap.uci.edu/JPF09747
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10 days ago
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Dr Dorota SK
Nature Chemical Biology
12 months ago
... And if you want to know more, here's the featured Article: Methylarginine targeting chimeras for lysosomal degradation of intracellular proteins ($)
doi.org/10.1038/s415...
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Methylarginine targeting chimeras for lysosomal degradation of intracellular proteins - Nature Chemical Biology
Development of a targeted protein degradation platform, methylarginine targeting chimera (MrTAC), enables arginine methylation-driven degradation of intracellular proteins in lysosomes.
https://doi.org/10.1038/s41589-024-01741-y
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This is so low.
www.nytimes.com/2025/10/28/o...
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Opinion | She Was Elected to Congress. She Can’t Get Into Her Office After Hours.
https://www.nytimes.com/2025/10/28/opinion/grijalva-congress-mike-johnson.html
about 1 month ago
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Up for a treat!
@stimulatedraman.bsky.social
presenting.
about 2 months ago
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💲💲💲 This research would not have been possible without the support of several funding agencies, including
#NIH
National Eye Institute,
@brightfocus.bsky.social
, Thome Foundation,
#RPB
, the
#NSF
, and the Simons Foundation. Our collaborators also received support from
#FNP
and
#NCN
. Thank you!!! 💲💲💲
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2 months ago
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Our work is finally out! Learning from mechanism of
#aging
to presenting potential therapeutic strategy to slow down
#age-related
#vision
loss! Very proud of my team including several undergrads and thankful for fantastic collaborations across the world!
www.science.org/doi/10.1126/...
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Retinal polyunsaturated fatty acid supplementation reverses aging-related vision decline in mice
Intravitreal delivery of an ELOVL2 product reduces age-related molecular changes in the retina and restores visual function.
https://www.science.org/doi/10.1126/scitranslmed.ads5769
2 months ago
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Dr Dorota SK
Jeremy Berg
3 months ago
New York Times story with profiles of researchers whose grants were terminated. [Gift Link]
www.nytimes.com/2025/08/24/o...
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Opinion | America First? Not When It Comes to Your Health.
https://www.nytimes.com/2025/08/24/opinion/trump-defunding-medical-research.html?unlocked_article_code=1.gk8.iN9o.HYW2vUoXfu0I&smid=url-share
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Dr Dorota SK
3 months ago
Thank you
@ash.hematology.org
for supporting our research spearheaded by
@silviavicenzi.bsky.social
in the lab! Excited to have the opportunity to jump-start the next stage of our exploration into
#bloodstemcell
#aging
with our collab &
#lipidomics
expert
@drdorotask.bsky.social
!
#Fight4Hematology
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Kathleen Bachynski
4 months ago
I’ll take every bit of good news I can get. “Senators from both parties endorsed a $400 million increase to the budget of the National Institutes of Health… in an Appropriations Committee vote that represents a clear rebuke of President Trump’s plan to dramatically reduce the agency’s spending.”
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Senate committee endorses NIH budget increase, rebuking Trump administration’s proposed 40% cut
Senators from both parties endorsed a $400 million increase to the budget of the National Institutes of Health on Thursday
https://www.statnews.com/2025/07/31/nih-budget-senate-committee-replaces-trump-cuts-with-400-million-increase/
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Fantastic work of
@evgenykvon.bsky.social
team.
@gracebower.bsky.social
did an amazing job. It was a pleasure to assist them even as little as we did. Hope for more collaborations in the future!!! Congratulations!!!!!
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5 months ago
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Dr Dorota SK
Paloma Liton
6 months ago
www.nytimes.com/interactive/...
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Here are the nearly 2,500 medical research grants canceled or delayed by Trump (Gift Article)
Some cuts have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye.
https://www.nytimes.com/interactive/2025/06/04/health/trump-cuts-nih-grants-research.html?unlocked_article_code=1.MU8.zPko.T8ojssGIlTW7&smid=bs-share
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Dr Dorota SK
Rachel W. Martin
6 months ago
Even though cataract surgery is generally safe and effective, cataract is still a leading cause of blindness worldwide. We need to understand the optical and materials properties of the eye lens to make better replacement lenses. This budget would eliminate that, including my lab's work.
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Jeremy Berg
6 months ago
Senator Durbin noted that some (I believe Republican Senators) had indicated the US had been doing more than its share of biomedical research and it was time for other countries take a turn. I felt I had to interrupt to respond...
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Dr Dorota SK
Carolyn Bertozzi
6 months ago
David Liu
@harvard.edu
beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors 👏
youtu.be/8YhJM6zxYDw?...
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Breakthrough Prize-Winning Biochemist on the Deadly Cost of Funding Cuts | Amanpour and Company
YouTube video by Amanpour and Company
https://youtu.be/8YhJM6zxYDw?si=V5iSZDdv-uwf9lui
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Dr Dorota SK
Paloma Liton
7 months ago
📣 TRAVEL GRANTS AVAILABLE for trainees and young investigators! Deadline: May 26 Don’t miss the opportunity to attend the ISER/BrightFocus Glaucoma Symposium & Fast Track with the support of a travel grant!
@iser.bsky.social
@brightfocus.bsky.social
👉
iserbrightfocusglaucoma.org/abstract-sub...
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Abstract Submission – Iser/Bright Focus Glaucoma Symposium
https://iserbrightfocusglaucoma.org/abstract-submission/
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Good morning!!! ☀️
7 months ago
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Dr Dorota SK
Neil deGrasse Tyson
7 months ago
The 80-year recipe stoking America’s Prosperity: 1) Free-market capital investments in brilliant ideas… 2) enabled by Engineering Innovations… 3) based on Science Research in Universities… 4) funded by Grants from the US Government. It’s time more people understood this.
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Dr Dorota SK
8 months ago
In
#myfirstpost
here, I'm excited to share the news that the Crews Lab's latest research on
#immunesystem
#aging
is now published in
@geroscience.bsky.social
! This work is the culmination of a wonderful collaboration with
@drdorotask.bsky.social
Lab with major efforts by
@silviavicenzi.bsky.social
!
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It was a great collaboration with
@crewslab.bsky.social
! Complementary expertise, curiosity and unique mouse model. Congrats
@silviavicenzi.bsky.social
and looking forward to working together to decipher the mechanism!
#aging
#Bcells
#PUFA
#ELOVL2
@ucirvine.bsky.social
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8 months ago
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Third time’s overrated — fourth time’s where the magic happens! I just got awarded a BrightFocus Foundation National Glaucoma Research grant! Thank you
@brightfocus.bsky.social
for your support!!!
#agingeye
#glaucoma
#epigeneticmemory
8 months ago
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Dr Dorota SK
MIT Press
8 months ago
We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.
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The Coming Out of a Transgender Scientist
"I know that I am making the right decision because whenever I think about changing my gender role, I am flooded with feelings of relief."
https://thereader.mitpress.mit.edu/the-coming-out-of-a-transgender-scientist/
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Dr Dorota SK
Mark Peifer (He, him)
8 months ago
14 pages of terminated NIH grants--everyone should read through the list. The sweep is VERY broad, including "The Impact of the Herpes Zoster Vaccine on Herpes Zoster Ophthalmicus" & "Mitochondrial-based Determinants of Sex Differences in Acute Kidney Injury"🧪 1/n
taggs.hhs.gov/Content/Data...
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https://taggs.hhs.gov/Content/Data/HHS_Grants_Terminated.pdf
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I had an amazing visit at
#WilmerEyeInstitute
! Great discussions and fantastic host, blueskyless Malia Edwards. See you all soon at
@arvoinfo.bsky.social
!!!
9 months ago
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On my way to Baltimore!Doing research and meeting colleagues!!
#Standingwithscience
9 months ago
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Is age-related macular degeneration (AMD) a type of retinal aging or a disease? Is there a difference between aging and early AMD? You can read about what we think about it here:
www.sciencedirect.com/science/article/abs/pii/S0014483525000740
#AMD
#aging
#AgingEye
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Features that distinguish age-related macular degeneration from aging
Age-related macular degeneration (AMD) is a complex, multifactorial retinal degenerative disease that is influenced by both genetic and environmental …
https://www.sciencedirect.com/science/article/abs/pii/S0014483525000740
9 months ago
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Dr Dorota SK
Samer Hattar
9 months ago
Oh wow
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#proud
to be
#Polish
💙
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Lech Walesa, Polish Labor Leader Who Fought U.S.S.R.’s Power, Joins in Horrified Letter to Trump
He and former Polish political prisoners voiced “horror and disgust” at President Trump’s scolding of President Volodymyr Zelensky of Ukraine last week, saying it reminded them of encounters with bull...
https://www.nytimes.com/2025/03/03/us/politics/lech-walesa-trump-letter.html
9 months ago
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After LOI submitted in November......
#Diversity
#Research
#support
10 months ago
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Dr Dorota SK
POSTDOCTORAL POSITION AVAILABLE in DSK laboratory. Studying Molecular Mechanism of Aging using eye as a model system. Looking for people with experience in epigenetics and transcriptomics. Apply until March 1st.
#aging
#AMD
#glaucoma
#epigenetics
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Arnold and Mabel Beckman Foundation Research Fellowship
University of California, Irvine is hiring. Apply now!
https://recruit.ap.uci.edu/JPF09295
10 months ago
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We should speak up! Petition initiated by Tom Maniatis. Please sign and amplify:
chng.it/8srHDmzpVk
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This campaign needs you now
Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)
https://chng.it/8srHDmzpVk
10 months ago
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POSTDOCTORAL POSITION AVAILABLE in DSK laboratory. Studying Molecular Mechanism of Aging using eye as a model system. Looking for people with experience in epigenetics and transcriptomics. Apply until March 1st.
#aging
#AMD
#glaucoma
#epigenetics
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Arnold and Mabel Beckman Foundation Research Fellowship
University of California, Irvine is hiring. Apply now!
https://recruit.ap.uci.edu/JPF09295
10 months ago
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Do you want to study MOLECULAR MECHANISM OF AGING? APPLY to work in my laboratory! Deadline March 1st.
recruit.ap.uci.edu/JPF09295
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Arnold and Mabel Beckman Foundation Research Fellowship
University of California, Irvine is hiring. Apply now!
https://recruit.ap.uci.edu/JPF09295
10 months ago
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POSTDOCTORAL RESEARCHER WANTED! If you want to work in the vibrant DSK laboratory using cutting edge methods and answering important scientific research questions APPLY!!! Deadline March 1st
recruit.ap.uci.edu/JPF09295
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Arnold and Mabel Beckman Foundation Research Fellowship
University of California, Irvine is hiring. Apply now!
https://recruit.ap.uci.edu/JPF09295
10 months ago
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Dr Dorota SK
Laura White
10 months ago
Made some slides for scientists to talk about what's been happening & what we should do next. There are probably many people better qualified than me to talk about these issues. If that's you, please, please, please consider holding some virtual advocacy training sessions for researchers this week.
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The War on Science (Feb 2025 teach-in draft)
The War on Science What’s happening? What can we do about it? An interactive teach-in for biomedical researchers Please share, modify, and repurpose this template presentation (with credit). Good luck...
https://docs.google.com/presentation/d/1TYHJ81tmY09q67-iUPNnqE0K02UZY3ZC7k6v-3q9AmQ/edit?usp=sharing
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Dr Dorota SK
Rell the Grinch 🎄
10 months ago
Nikes first Superbowl commercial in 27 years. What a way to pop back out 🔥
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anybody got this when signing to eRA commons? 😱
10 months ago
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Dr Dorota SK
Senator Ron Wyden
10 months ago
NEW: Sources tell my office that Treasury Secretary Bessent has granted DOGE *full* access to this system. Social Security and Medicare benefits, grants, payments to government contractors, including those that compete directly with Musk's own companies. All of it.
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Dr Dorota SK
Nancy Kanwisher
10 months ago
Senators to call: John Thune, SD (202) 224-2321 Bill Cassidy, LA (318) 448-7176 Lisa Murkowski, AK (202)-224-6665 Mike Crapo, ID (202) 224-6142 Mitch McConnell, KY (202) 224-2541 Susan Collins, ME (202) 224-2523 Thom Tillis, NC (704) 509-9087 Mike Rounds, SD (202) 224-5842
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Dr Dorota SK
Nicole Rust
10 months ago
This is legit - the organizers (including unions) are organizing. When I ask those in the know what we can do that will actually matter, the answer includes collective action of this type. I'm joining
@nancykanwisher.bsky.social
and all the others for this Thurs 3p ET effort. I hope you do too!
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This is a disaster.
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11 months ago
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Dr Dorota SK
Laura Haynes👩🔬⚾️🐾💙
11 months ago
This is excellent!!!! I wish more infectious disease experts responded to anti-vaxxers like this guy did
#GetVaccinated
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Dr Dorota SK
Rob Mullins (he/him)
11 months ago
Vision Science Peeps--nominate a colleague for an
@arvoinfo.bsky.social
achievement awards!
www.arvo.org/awards-grant...
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The Association for Research in Vision and Ophthalmology- Achievement Awards
https://www.arvo.org/awards-grants-and-fellowships/arvo-achievement-awards/
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Dr Dorota SK
Alice Kane
11 months ago
Check out the first publication from the Kane lab
@isbscience.org
! RNAseq analysis of sex differences in aging across tissues - spoiler alert - there are lots of them!
bsd.biomedcentral.com/articles/10....
Congratulations and thans to
@dantong-zhu.bsky.social
,
@judywbio.bsky.social
& other authors.
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Sex dimorphism and tissue specificity of gene expression changes in aging mice - Biology of Sex Differences
Background Aging is a complex process that involves all tissues in an organism and shows sex dimorphism. While transcriptional changes in aging have been well characterized, the majority of studies ha...
https://bsd.biomedcentral.com/articles/10.1186/s13293-024-00666-4
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Dr Dorota SK
ISER
12 months ago
Congratulations Newly Elected ISER Officer, Vice President, Americas Paloma Liton, PhD Duke University Durham, NC
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Dr Dorota SK
Julie Campbell
12 months ago
An ongoing passion project of mine at work: making small info placards about women in STEM that hang in our campus biology building. Their stories give me strength & hope especially now when we face 4 years of darkness. Here is the 1st of many I'll be sharing.
#WomeninSTEM
#academicsky
#skystorians
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Great science in a great place. Obergulg 😍.
12 months ago
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Thank you
@ucirvine.bsky.social
for highlighting our work!
news.uci.edu/2024/12/03/u...
#agingeye
#womeninscience
#collaborations
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UC Irvine-co-led study finds DNA damage is key factor in age-related macular degeneration
Targeting specific retinal cell types could lead to treatments that slow or stop progression
https://news.uci.edu/2024/12/03/uc-irvine-co-led-study-finds-dna-damage-is-key-factor-in-age-related-macular-degeneration/
about 1 year ago
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Thomas P200 Burke
about 1 year ago
I'm pumped to finally share our lab's first publication! Microbiology and cancer are deeply intertwined, and this is our first foray into the cancer field. We asked: how do bacteria activate innate immunity in tumors to elicit anti-cancer responses?
www.sciencedirect.com/science/arti...
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Cytosolic bacterial pathogens activate TLR pathways in tumors that synergistically enhance STING agonist cancer therapies
Intracellular bacterial pathogens are distinctive tools for fighting cancer, as they can proliferate in tumors and deliver therapeutic payloads to the…
https://www.sciencedirect.com/science/article/pii/S2589004224026105
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First announcement from DSK lab here: a new work just came out - we connected DNA damage to the loss of vision and aging. Amazing collab with Niedernhofer lab. And more to come!!
doi.org/10.1111/acel...
#agingeye
#vision
#aging
#AMD
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The Ercc1−/Δ mouse model of XFE progeroid syndrome undergoes accelerated retinal degeneration
Spontaneous endogenous DNA damage drives key hallmarks of age-related retinal degeneration, including visual impairment, photoreceptor cell loss, dysmorphic RPE, mitochondrial dysfunction, and cellul....
http://doi.org/10.1111/acel.14419
about 1 year ago
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Dr Dorota SK
BrunetLab
about 1 year ago
Updated Aging Starter Pack!! People and labs interested in aging 😀 Let me know if you'd like to be added!
go.bsky.app/5UXXaDA
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