AlphaFold DB v6 (synced with UniProt 2025_03) is live! Here are the details: Totals v4 → v6: 241,070,489 entries. Since v4: +65,711,653 added, 39,324,993 removed, 276,539 changed (in sequence), 175,082,297 unchanged (metadata refresh, relabelled v6). Details 👇

📣 HUGE ANNOUNCEMENT! Drum roll please 🥁🥁🥁🥁🥁🥁🥁 Introducing Positron, a free code editor built specifically for data science. Learn more about what you can do with Positron: posit.co/blog/positro...

For #InternationalMicroorganismDay, we asked our FEMS MICRO 2025 Keynote Speakers and FEMS Journal Editors "'What is your favourite microbe?'' With delightful answers, ranging over many microbes and personal stories, this was the perfect way to celebrate IMD 2025! #MicroSky youtu.be/oEJsWNJCtBw

Today on World Sepsis Day, neonatal sepsis remains a major killer, taking over 400,000 newborn lives each year, driven by weak immunity, delayed care, and #AMR. Strengthening hygiene, diagnostics, and timely treatment is crucial to closing the survival gap. www.financialexpress.com/life/health/...

Ten simple rules for navigating #AI in #Science @plos.org

🧪 We're beta testing – and we want your thoughts! Try the new PDBe-KB Complex pages and let us know: 🔸 What’s working? 🔸 What’s confusing? 🔸 What features are lacking 💬 Feedback form: tinyurl.com/pdbekb-compl... #PDBeKB #Complexes #Bioinformatics #StructuralBiology #Science

Virtual Lab #AI www.czbiohub.org/news/with-no...

PhyloScape: interactive and scalable visualization platform for phylogenetic trees. r#PhylogeneticTees #Visualization #Bioinformatics #BMCbioinformatics bmcbioinformatics.biomedcentral.com/articles/10....

Genomic reproducibility in the bioinformatics era genomebiology.biomedcentral.com/articles/10.... 🧬🖥️

Exploring R and Rust in Bioinformatics - online developer forum blog.bioconductor.org/posts/2025-0... #Rstats #rustlang

#AlphaGenome: #AI for better understanding the #genome deepmind.google/discover/blo...

Tissue specific protein-protein associations #atlas #ppi #disesse

#Candida auris - emerging pathogen of #UTI

🧬 Out today 🧬 - our TyphiNET #AMR surveillance dashboard for #typhoid Use TyphiNET to view genome-derived data on global and national annual trends in AMR and circulating pathogen genotypes via any standard web browser. genomemedicine.biomedcentral.com/articles/10....

#Programming for research

Margaret Dayhoff! #Bioinformatics www.nature.com/articles/s43...

Genome modeling and design across all domains of life with Evo 2 | bioRxiv www.biorxiv.org/content/10.1...

Foldseek 10 with 4-27x (1-8 GPUs) faster search through MMseqs2-GPU. Faster ProstT5 protein search w/o structure prediction through multi-GPU/Apple Metal, new BFVD/BFMD databases and multimer clustering (preview). 💾 github.com/steineggerla... 📄 www.biorxiv.org/content/10.1... 🐍 available in bioconda

#KlebPhaCol www.biorxiv.org/content/10.1... #klebsiella #phage

Bacteria’s Stress Strategy: Slow Down to Avoid the Crowd www.the-scientist.com/bacteria-s-s... #bacteria #stress #simulation

www.ipd.uw.edu/2024/11/intr... #peptidedesign #diffusion

www.nature.com/articles/d41... #longevity #aging

Language Models for Molecular Dynamics www.biorxiv.org/content/10.1... #languagemodel #moleculardynamics

EasyPubPlot: a shiny web application for rapid omics data exploration and visualization https://www.biorxiv.org/content/10.1101/2024.11.26.625339v1

We’re excited to release a major update to the Boltz repo: v0.3.0. This release contains several important new features, including our confidence model and memory-efficient inference. Give it a try! github.com/jwohlwend/bo...

MMseqs2 Release 16 Highlights: GPU-accelerated search📄, ORF or new 6-frame translated search modes, contig taxonomy always keeps the longest ORF, bug fixes (reduced memory and higher sensitivity) and relicensed as MIT 📄 biorxiv.org/content/10.1... 💾 mmseqs.com and 🐍Bioconda 🖥️🧬🧶

#NetworkCommons: bridging data, knowledge and methods to build and evaluate context-specific biological #networks www.biorxiv.org/content/10.1...

UniProt: the Universal Protein Knowledgebase in 2025 academic.oup.com/nar/advance-... #jcampubs

#WhatIsMyGene: Back to the Basics of Gene Enrichment www.biorxiv.org/content/10.1... #enrichment #genes

#PanTax: Strain-level taxonomic classification of metagenomic data using #pangenome graphs www.biorxiv.org/content/10.1... #microbiome #metagenomics #taxonomy

Your friends shape your microbiome — and so do their friends Analysis of nearly 2,000 people living in remote villages in Honduras reveals who’s spreading gut microorganisms to whom. www.nature.com/articles/d41...

#Harmonizome 3.0: integrated knowledge about genes and proteins from diverse multi-omics resources academic.oup.com/nar/advance-... #knowledgegraph #multiomics #genes #data #llm

#Gaia: A Context-Aware #Sequence Search and Discovery Tool for Microbial #Proteins www.biorxiv.org/content/10.1... #languagemodel #llm

CellBinDB: A Large-Scale Multimodal Annotated Dataset for Cell Segmentation with Benchmarking of Universal Models https://www.biorxiv.org/content/10.1101/2024.11.20.619750v1

What is the real value of #omics data? Enhancing #research outcomes and securing long-term data excellence academic.oup.com/nar/article/...

#AI-readiness for #Biomedical Data: Bridge2AI Recommendations www.biorxiv.org/content/10.1...

Global ocean #microbiome catalogue: A gateway to unlock marine microbial resources and #ecosystem functions www.the-innovation.org/article/doi/...

#Boltz-1: Democratizing Biomolecular Interaction Modeling www.biorxiv.org/content/10.1... #biomolecules #interactions

Database updates -The Pfam protein families database: embracing AI/ML academic.oup.com/nar/advance-... - UniProt: the Universal Protein Knowledgebase in 2025 academic.oup.com/nar/advance-... - RASP v2.0: an updated atlas for RNA structure probing data academic.oup.com/nar/advance-...

If you're building AI models for drug discovery, you should check out the newly open-source #BioNeMo Framework: code: github.com/NVIDIA/bione... paper: arxiv.org/abs/2411.10548 docs: docs.nvidia.com/bionemo-fram... explainer: t.co/7MOamSChGN

APAtizer: a tool for alternative polyadenylation analysis of RNA-Seq data. #PolyA #AlternativePolyadenylation #RNAseq #Sequencing #Bioinformatics 🧬 🖥️ academic.oup.com/bioinformati...

All about #Bioinformatics! go.bsky.app/ExYDQFv