Inflammatory cytokines can hijack mTORC1 in #cancer cells, resulting in amino acid competition with #CD8+ cells and starved #immunity. We discuss findings from Xiang et al in our News&Views article for @natcellbio.nature.com www.nature.com/articles/s41... Full access: rdcu.be/fh2a6

Urolithin A supplementation for 28 days shifted immune cell profiles in older adults toward a more youthful, less exhausted state and enhanced mitochondrial fatty acid oxidation capacity. doi.org/g99kft

In a RCT, Urolithin-A boosted CD8⁺ T cells and improved immune metabolism, hinting at a new way to slow age-related immune system decline and inflammaging. buff.ly/qaGyGF0 Urolithin A works by inducing mitophagy (clearance of damaged mitochondria). #medsky #aging

Excited to share our new study in @nataging.nature.com !🎉 www.nature.com/articles/s43... We show that Urolithin A, a pomegranate-derived gut metabolite, counteracts key signs of immune #aging in a phase I trial! #immunology #aging @loewe-fci.bsky.social @goetheuni.bsky.social #immunosky

Happy to repost the study in @cp-immunity.bsky.social now with the cover illustrating the Janus-faced role of IL-17RA in #colorectalcancer. More information below by @domdenkmd.bsky.social or the latest issue of Immunity: www.cell.com/immunity/cur... #DarmkrebsmonatMärz @proloewe.bsky.social

Online now: Online now: IL-17RA signaling provides dual tumor-suppressor function during late-stage colorectal carcinogenesis

Fresh from @cp-immunity.bsky.social "A Surprising Shift from Foe to Friend: Researchers discover dual role of inflammatory signaling in colorectal cancer" 👏Congratulations @domdenkmd.bsky.social and all coauthors!! 🎉 Read the full article here: www.cell.com/immunity/ful... @proloewe.bsky.social

Finally announcing our new study in @cp-immunity.bsky.social! We show that IL-17RA fulfills dual tumor suppressor function in late-stage colorectal cancer (CRC)! #immunosky #cancer #immunology @loewe-fci.bsky.social @cellpress.bsky.social @goetheuni.bsky.social Read here🧵👇: tinylink.net/OS41F

Good morning, all. A rich and diverse list of curated papers in #cancermetabolism and #mitochondrialbiology is ready for you! Don't miss it! Find it here: biomed.news/bims-camemi/... @biomednews.bsky.social "In the midst of winter, I found there was, within me, an invincible summer."-Albert Camus

Good Sunday, all! A short but rich summary of papers in #cancermetabolism and #mitochondrialbiology is waiting for you here: biomed.news/bims-camemi/... @biomednews.bsky.social #dontstopreading “The Eyes See Only What The Mind Is Prepared To Comprehend.” ― Henri Bergson