new out in Nature www.nature.com/articles/s41...

Very happy to share our new paper. Together with our wonderful collaborators, we found that L-2-HG, a metabolite often viewed as “toxic,” also has an essential physiological function in mice. www.nature.com/articles/s41...

Now online! Mitochondrial activity tunes nociceptor resilience to excitotoxicity

Mitochondrial activity tunes nociceptor resilience to excitotoxicity: Cell www.cell.com/cell/fulltex...

Modulating levels of a mitochondrial metabolite can direct intestinal stem cells to specialise for absorption or secretion https://go.nature.com/3ZrJ0HI

A key component of the TCA cycle, 2-oxoglutarate dehydrogenase, dictates the fate of intestinal stem cells during tissue regeneration @nature.com www.nature.com/articles/s41... www.nature.com/articles/d41...

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

But…..ok, ok, I’m convinced. Elegant and definitive. www.science.org/doi/10.1126/...

Our lab's latest study, spearheaded by a fantastic colleague, Colleen, reveals that the blood glucose-lowering effect of metformin requires the inhibition of mitochondrial ETC complex I. www.science.org/doi/10.1126/.... An insightful focus by Prof. Doug Green: bit.ly/41Hc4fX

Big and well-deserved congrats to #NoBlueskyNav on another year in the Clarivate Highly Cited Researchers list in both Molecular Biology and Immunology! clarivate.com/highly-cited...

Since Nav will never tweet about it

Clear and comprehensive new go-to review from #NoTwitterNav (we're gonna need a new hashtag) delineating how mitochondria have distinct and context-specific roles in proliferation and fate determination www.annualreviews.org/content/jour...