@gyrd-lab.bsky.social
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reposted by
Meier Lab ICR
2 months ago
Our new study is out in Nature Communications. Using TNBC organoid mouse models, we show that necroptosis in both tumour and stromal compartments cooperatively drives effective responses to immunogenic cell death–based immunotherapy. 🔗
www.nature.com/articles/s41...
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Necroptosis in both tumour and stromal compartments determines responsiveness to immunogenic cell death-based immunotherapy - Nature Communications
Most advanced triple-negative breast cancers remain resistant to immunotherapy. Here, the authors discover that RIPK1-driven necroptosis in both tumor and stromal compartments is essential for effecti...
https://www.nature.com/articles/s41467-026-70133-8
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reposted by
Nature
about 2 months ago
Bacteria have been fighting off viruses using a huge arsenal of molecular weaponry that scientists did not know about — until now. Researchers have identified proteins that could lead to virus-fighting drugs and technologies.
go.nature.com/4dqQnXI
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‘Treasure trove’ of antiviral proteins could inspire powerful molecular tools
Two research teams mined genomic data from bacteria to create databases containing thousands of antiviral defence proteins that could inspire powerful biotechnologies.
https://go.nature.com/4dqQnXI
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I am delighted that our study “Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF”, led by Biao Ma, is published in Science Immunology.
#TNFR1
,
#inflammation
,
#CellDeath
,
#Immunopathology
,
#Tissue_tolerance
@sic-ucph.bsky.social
@ludwigcancer.bsky.social
doi.org/10.1126/scii...
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Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF
Upstream open reading frames exert translational control of TNFR1, which limits tissue responsiveness to TNF.
https://doi.org/10.1126/sciimmunol.aeb6484
about 2 months ago
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reposted by
Waggoner Lab
about 2 months ago
Upstream open reading frames exert translational control of TNFR1, which limits tissue responsiveness to TNF
@sciimmunology.bsky.social
@gyrd-lab.bsky.social
@ox.ac.uk
www.science.org/doi/10.1126/...
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reposted by
Journal of Experimental Medicine
about 2 months ago
ICYMI: This collection highlights the latest discoveries in the field of
#InnateImmunity
in viral
#infection
, barrier defense, liver health,
#inflammation
, and
#cancer
. Explore latest discoveries in JEM 👉
rupress.org/jem/collecti...
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reposted by
Yogesh Kulathu
about 2 months ago
Registration now open! 2026
#EMBO
#Ubiquitin
Workshop set in stunning Monopoli, Puglia 🇮🇹 Cutting edge science, great speakers, short talk opportunities, travel awards Limited spaces. Dont miss out - register early! Registration & more info:
meetings.embo.org/event/26-ubi...
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reposted by
Waggoner Lab
2 months ago
Perspective
@cp-cellchembiol.bsky.social
Transcending cell death – The diverse roles of necroptosis signal adaptors in pathogen infection
www.cell.com/cell-chemica...
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Join us for the EMBO workshop on Pathogen Immunity and Signalling
#embopathogensignalling
Abstract submission extended until 15 February.
bsky.app/profile/embo...
add a skeleton here at some point
4 months ago
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This is an excellent meeting for anyone interested in immunology, virology, host-pathogen interactions, immune signalling. Abstract submission deadline is 1 Feb.
add a skeleton here at some point
4 months ago
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reposted by
EMBO
7 months ago
Explore #immunology, #virology, #microbiology and more at EMBO Workshop "Pathogen Immunity and Signalling" in Leiden, NL, 8–11 June 2026. Abstract submission/Registration deadline: 1 February/15 March
https://meetings.embo.org/event/26-pathogen-immunity
#immunology
#virology
#microbiology
#EMBOpathogenSignalling
#EMBOevents
🧪
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Pathogen Immunity and Signalling
Viruses, bacteria, and other pathogens pose a serious threat to human health, requiring a coordinated response from the innate and adaptive immune systems. Our immune system relies on pathogen recept…
https://meetings.embo.org/event/26-pathogen-immunity
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reposted by
LEO Foundation Skin Immunology Research Center (SIC)
5 months ago
📣 SIC Summer School 2026 — applications open! 📍Hornbæk, DK | 18–20 May 2026 🎯Theme: Skin Immunity & Homeostasis 💵Free (stay + meals). For PhD students & postdocs. ✍️Deadline: 15 Jan 2026 (23:59 CET). 🔗Full details:
sic.ku.dk/summerschool/
🔗Register here:
eventsignup.ku.dk/sicss2026
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