New lab paper in #ScienceAdvances: we identify a modality-common selective-attention signal in noncholinergic #BasalForebrain (BF) “bursting” neurons, distinct from the modality-specific attention signals typically described in corticothalamic circuits. 1/n www.science.org/doi/full/10....

🚨Our preprint is online!🚨 www.biorxiv.org/content/10.1... How do #dopamine neurons perform the key calculations in reinforcement #learning? Read on to find out more! 🧵

Now out in @natcomms.nature.com‬: Mice and monkeys spontaneously shift through comparable cognitive states - and it's written all over their faces! (1/7) www.nature.com/articles/s41...

Together with this paper by the group of Joe Paton www.nature.com/articles/s41... our results across the two papers complement each other providing strong evidence that distinct dopamine neurons discount future rewards at different rates providing a substrate for multi-timescale RL in the brain

Our work with Pablo Tano, @hyunggoo-kim.bsky.social Athar Malik, Alexandre Pouget and @naoshigeuchida.bsky.social exploring how dopamine neurons could enable multi-timescale reinforcement learning in the brain is out in @nature.com www.nature.com/articles/s41...

Great work from my next door neighbor!

Big Congratulations Tsai-Wen! www.nature.com/articles/s41...

Impressive study in @nature from my colleague Marcus Stephenson-Jones at UCL in the @sainsburywellcome.bsky.social www.nature.com/articles/s41...

1/7 Our paper on individual variability in decision-making is finally out in @nature.com! Inspired by the classic work by Mante and Sussillo, we trained many rats to solve context-dependent decision-making, and we found that different brains use different neural mechanisms to solve the same task!

Congrats to @kepecslab.bsky.social !

Some glimmers of hope (but mostly confusion) this morning. I have heard that no intramural tenure track investigators were supposed to be on the termination list although some folks clearly got termination notices. I am actively checking into this every way I can. 1/2

This is atrocious!

Very interesting paper on a potential role for proprioceptors in sensing muscle acidosis and driving the perception of soreness. "Sng" is a Taiwanese word for both sour taste and muscle soreness. It also imitates the natural vocalization of humans feeling sore. www.science.org/doi/10.1126/...

(1/30) New preprint! "Symmetries and continuous attractors in disordered neural circuits" with Larry Abbott and Haim Sompolinsky bioRxiv: www.biorxiv.org/content/10.1...

Two papers out showing that thalamic inputs determine how cortex responds to a hierarchical task with rule switching: www.nature.com/articles/s41... journals.plos.org/plosbiology/... 🧠📈 🧪

These essays offer the neuroscience community a place to explore the culture and practice of the field; to debate major questions; to examine the craft of neuroscience; and to trace its evolution over time. Download the book now: www.thetransmitter.org/transmitter-...

Our preprint of my PhD’s work in @gisellavetere.bsky.social lab is finally out on BiorXiv: doi.org/10.1101/2024..., and I’m so excited to share it! If you’ve ever wondered about reconciling engram manipulation experiments and neuronal activity during encoding, you’re on the right thread! 1/14

Neuroscience students asked us to teach a PRACTICAL course on experimental methods, and it is now on YouTube! Please like and repost to help us get the word out! www.youtube.com/playlist?lis... Lecture 1: Signals and data acquisition Focusing on hardware, digital/analog I/O, synchronization 🧵

Really elegant work by @behrenstimb.bsky.social group. The idea of structured memory buffers provides a nice framework to understand 'goal-progress cells’ activity in the mPFC while mice learn a common task structure across many tasks. Not the easiest paper to read but really worthwhile!

Thrilled to present our latest BioRXiv on brain/body interactions during defensive freezing behaviour! (www.biorxiv.org/content/10.1...). You might think that a frozen animal has, well, frozen muscle activity, right? Wrong! Underneath the still surface of a fly, something in the legs is beating… 🧵

Thanks Kevin! And thanks to my collaborators @alexkoulakov.bsky.social Sergey Shuvaev and Divyansha Lachi ! (S & D -- have you joined the party here yet?)

Another huge influx of colleagues to BlueSky this week, so let me attach the fully updated Neurophysiology starter pack for anyone interested. go.bsky.app/9FY1ReG

OpenScholar: AI for scientific paper research - Finds papers & summarizes content for user queries - Trained on 45M+ Semantic Scholar papers - 8B parameters GitHub: github.com/AkariAsai/Op...

Just immigrated to Bsky. Really like the atmosphere and discussions here and reminded me of why I loved science twitter. Starter packs are very helpful and there are tools to convert starter packs into lists like this one: nws-bot.us/bskyStarterP...

Huge influx of neuroscientists migrates to Bluesky www.thetransmitter.org/community/hu... #Neuroscience

Just put together the beginnings of a systems & behavior neuro starter pack (focus on rodent work) - obviously a lot of people missing, and most included are in my own little bubble, so if you want to be added do reply here! go.bsky.app/Hxpe53o

I made a systems neuroscience starter pack, focused on experimentalists who study the brain at the level of populations of neurons! Also want to be on the list? Reply or DM me a picture of your ephys rig or 2p setup and I'll add you 🤭 go.bsky.app/UiqX7ry