Quality measurement was once a breakthrough. But today it’s too slow, too costly, and too disconnected from daily care. It’s time to reinvent it. 🆕 My Editor’s Page in JACC: www.jacc.org/doi/epdf/10.... @jaccjournals.bsky.social @yalemed.bsky.social

“Everyone thinks their genes are the cause for them getting an age-related disease, it’s actually your immune system.” - @erictopol.bsky.social the author of Super Agers on #HealthandVeritas podcast pod.link/1588414491/e... @thehowie.bsky.social @hmkyale.bsky.social

A conversation on Healthy Aging with @hmkyale.bsky.social and @thehowie.bsky.social @yaleschoolofmed.bsky.social insights.som.yale.edu/podcasts/hea...

New @JACCJournals: Guiding the AI Revolution in CV Medicine I lay out 5 operational principles—from rigorous validation to bias reduction—to make AI safe, equitable & impactful in cardiology. ➡️ www.jacc.org/doi/10.1016/... @jaccjournals.bsky.social @yalemed.bsky.social @yaleschoolofmed.bsky.social

Biology, not blame. That’s the message from #ESCCongress. Fat is not just storage, it’s an organ. Its signals may drive heart failure and more. Read my take: Fat, Reframed: A Turning Point in Heart Disease. substack.com/home/post/p-... @jaccjournals.bsky.social @yaleschoolofmed.bsky.social

1/4 Rehabilitation can ⬆️ Functional Independence and ⬇️ Long-term Cognitive Impairment among #ICU survivors. But how often do hospitals deliver it? Led by @yalemedicine.bsky.social resident Jose Victor, our paper bit.ly/41p9fPT in @accpchest.bsky.social provides insights

New @JACCJournals Editor’s Page: A Disquieting Plateau 🫀 Cardiovascular mortality progress has stalled 📉 In some areas, it’s reversing 💡 We must confront what’s happening on our watch—and what comes next 👉 authors.elsevier.com/a/1lfjn2d9GI... #CardioTwitter #HealthEquity @jaccjournals.bsky.social

In my new Substack post... Did you know air pollution can raise blood pressure? I break down a just-published JACC trial testing HEPA filters in homes near highways—and what it means for heart health. @jaccjournals.bsky.social 👉 neverdelegateunderstanding.substack.com/p/00314b6f-e...

Can a HEPA filter protect the heart? My latest JACC #DeepDive explores a new trial of in-home air filtration—what it found, why the effect size matters, and how it fits into decades of research on air pollution and CVD risk. 🎧 www.jacc.org/digital-cont... @jaccjournals.bsky.social

🎙️ New JACC This Week podcast! This issue features: 🔹 CSPACE RCT — CSP vs RV pacing in AV block 🔹 HEPA filtration & blood pressure 🔹 FLAVOUR 6-year follow-up—FFR vs IVUS 🔹 Editor’s Page: excess CV mortality in Black Americans 🎧 Listen: www.jacc.org/digital-cont... @jaccjournals.bsky.social

Did COVID-19 really age our arteries? A major new study says yes—esp in women. But is it true? I take a deeper look to see if the evidence matches the headlines. Read it here → neverdelegateunderstanding.substack.com/p/did-covid-... #COVID19 @virusesimmunity.bsky.social @yalemed.bsky.social

“Never delegate understanding.” That quote stuck with me—and it’s now the title of my new Substack. I’ll be writing about health, science, & how these things can be understandable. Subscribe here → neverdelegateunderstanding.substack.com/subscribe #health #science #medicine @yalemed.bsky.social

🎙️ New #JACC Deep Dive MASTER DAPT recurrent events analysis goes beyond the first event, revealing total burden of ischemia & bleeding in PCI patients. Why we published it, what we learned, & how it changes the view. 🎧 Listen: www.jacc.org/digital-cont... #CardioTwitter #DAPT #HBR #PCI

From device safety to novel valve design—the new JACC This Week podcast covers: 🔹 Clinician-led device safety 🔹 MASTER DAPT recurrent events 🔹 Drug-coated balloons for complex ISR 🔹 Polymer surgical mitral valve Listen: bit.ly/4ove0Bn #JACCPodcast #Cardiology @jaccjournals.bsky.social

🎙️ New JACC This Week: 🧬 Mini-Focus on Amyloid Heart Disease 🫀 Vutrisiran echo + biomarker insights ✍️ Editor’s Page on access + innovation 🩼 Bonus: VVS trial + DOACs in frailty Listen now ⤵️ 🔗 www.jacc.org/digital-cont... @jaccjournals.bsky.social #cardiotwitter #amyloidosis

We’re drowning in data, but are we helping patients? In this #JACC Editor’s Page, Dr. @hmkyale.bsky.social challenges us to ask better questions in #HeartFailure care. If you think you know HF, read this: www.jacc.org/doi/10.1016/... #CardioSky #MedSky

🎧 New JACC This Week podcast: • SOGALDI-PEF: Dual therapy in HFpEF—worth it? • HFimpEF: Big data, big risk • Finerenone withdrawal • LMNA stroke risk • DSP & sex-specific risk • Rethinking ICDs 🎙️ Listen: www.jacc.org/digital-cont... #CardioTwitter @jaccjournals.bsky.social

🎙️ New JACC Deep Dive: Why did ACURATE neo2 fail in the IDE trial? Post hoc analysis suggests valve underexpansion may be part of the answer. Even with normal gradients. Even with a good echo. We explore what happened—and what’s next. 🔗 www.jacc.org/digital-cont... @jaccjournals.bsky.social

🎧 New #JACC This Week podcast 🔬 Valve underexpansion & outcomes in ACURATE IDE 💉 Body composition & tirzepatide in HFpEF 🏥 Private equity & heart failure care 🫀 Multivalve disease challenges 🧾 Brief reports+more ▶️ Listen: www.jacc.org/digital-cont... #cardiotwitter @jaccjournals.bsky.social

🎙️New Health & Veritas: A Visit from Your Local Epidemiologist We talk w/@kkjetelina.bsky.social about: • Building trust in public health • Making science clear—not scary • What’s next for COVID, H5N1, measles & more @yalesph.bsky.social @yalesom.bsky.social @thehowie.bsky.social

New Health & Veritas drops tomorrow! We’re joined by the incredible @kkjetelina.bsky.social — epidemiologist, communicator, & author of Your Local Epidemiologist. We talk public health, trust, & translating science for millions. @thehowie.bsky.social @yalesph.bsky.social @yalesom.bsky.social

“CV Prevention is in reach but only w/ implementation that’s global, upstream, and grounded in data.” In this week’s #JACCThisWeek, I highlight Focus Issue on Prevention: polypills, syndemics, PREVENT, inclisiran, and more. @jaccjournals.bsky.social 🎧 Listen here: www.jacc.org/digital-cont...

#JACC’s Guideline Spotlight debuts with the 2025 ACS Guideline 🚨 Featuring insights from Drs. Eugene Braunwald, Valentin Fuster, Robert M. Califf, & more—bold perspectives that inform, challenge & inspire Start browsing 👉 jacc.org/toc/jacc/85/... #cvACS #ClinicalGuidelines @hmkyale.bsky.social

The new #JACC spotlight issue flips the script: guidelines take center stage. Not an afterthought—this is the main event. Read why it matters 👉🔗 www.jacc.org/doi/10.1016/... #cvACS #ClinicalGuidelines @hmkyale.bsky.social

Using administrative claims and EHR databases rates of benign tumors and thyroid #cancer were not different in 460,032 users of GLP-1RAs vs. Users of other glucose lowering agents #diabetes @hmkyale.bsky.social diabetesjournals.org/care/article...

Great episode of Health & Veritas with Dr. Dave Chokshi! @hmkyale.bsky.social talks about his trip to China. I talk about helping to save 1 Million cases of congenital rubella syndrome over the next 30 years! insights.som.yale.edu/podcasts/hea...

“permissive firearm laws contributed to thousands of excess firearm deaths among children living in states with permissive policies” - the study by @jeremyfaust.bsky.social @mirandayaver.bsky.social @bhrenton.bsky.social @hmkyale.bsky.social et al (more tags!) in @jama.com Peds

Excited that my JAMA Pediatrics article with @jeremyfaust.bsky.social @bhrenton.bsky.social @hmkyale.bsky.social and others is now published. It turns out that permissive firearm laws aren’t great if you want to reduce pediatric firearm deaths. jamanetwork.com/journals/jam...

Our paper: since SCOTUS McDonald v. Chicago decision, states w/permissive firearm laws have had thousands of excess pediatric firearm deaths. 📊 6,029 excess deaths in the most permissive states 📈 Especially sharp rise among Black children 🔗 jamanetwork.com/journals/jam... @jeremyfaust.bsky.social

Lessons from Celect: What One Medical Device Taught Us About the Need for Transparency @jaccjournals.bsky.social 1/ In 2007, Celect IVC filter marketed as a safe way to prevent PE. By 2024: lawsuits, safety concerns, & calls for reform. Here’s what we can learn 👇 www.jacc.org/doi/full/10....

Important early study of #NIH research cuts by @hmkyale.bsky.social & colleagues in @jama.com. No grants administered by NIH Clinical Center or NCCIH were terminated; cumulative terminated grant funding=$1.81 billion, 30% of which had not been expended at termination jamanetwork.com/journals/jam...

New from @hmkyale.bsky.social, radical transparency on canceled #NIH grants. Largest number of terminated grants administered by Nat Inst of Mental Health (128) and Nat Inst on Minority Health and Health Disparities. #MedSky #PsychSky #politics #science

In divided times, #HealthCare must be more than a bystander. 🩺 #JACC Editor-in-Chief Dr. Harlan Krumholz, @hmkyale.bsky.social, calls on medicine to become a bridge, not a wall. Read why the time for courage is NOW: www.jacc.org/doi/10.1016/... #CardioSky #MedSky

I wrote this @jaccjournals.bsky.social because medicine should transcend borders & unite communities through shared purpose, evidence, and compassion. Words alone won’t change the world, but they can inspire actions and bring people together. www.jacc.org/doi/10.1016/... @yalemed.bsky.social

How to Lead a Chronic Disease Revolution. Proud to co-author this @wsj.com opinion piece with the incomparable @VirusesImmunity; we suggest that to make a dent in chronic disease, we should focus on post-infectious syndromes. @yalemed.bsky.social www.wsj.com/opinion/how-...

Trying something new: 🎙️ JACC Deep Dive: ~10 min podcast exploring topic/paper. Kicking off w/Altshock-2 trial (IABP in HF-related cardiogenic shock) + commentary on how the review unfolded. 🔗 www.jacc.org/digital-cont... Would love your feedback—keep going? @jaccjournals.bsky.social #Cardiology

New on @jaccjournals.bsky.social Deep Dive: Pulsed Field Ablation (PFA) for persistent AF is growing. I look into ADVANTAGE-AF trial, examining progress & work to be done. jacc.org/doi/10.1016/... 🎧 Listen now. Stay curious. jacc.org/digital-cont... #PFA #AtrialFibrillation #Cardiology

In Jan 2023, Damar Hamlin collapsed during NFL game & survived thanks to immediate CPR & AED use. But what do survival outcomes look like for young athletes across the U.S.? www.jacc.org/doi/10.1016/... New @jaccjournals.bsky.social Deep Dive episode explores the data. www.jacc.org/digital-cont...

Trying something new: 🎙️ JACC Deep Dive: ~10 min podcast exploring topic/paper. Kicking off w/Altshock-2 trial (IABP in HF-related cardiogenic shock) + commentary on how the review unfolded. 🔗 www.jacc.org/digital-cont... Would love your feedback—keep going? @jaccjournals.bsky.social #Cardiology

New @JACCJournals Editor’s Page: Black Lives, Cardiovascular Deaths Cardiovascular disparities cost Black Americans 23.7 million years of life from 2000–2022. 📖 authors.elsevier.com/a/1kwz92d9GI... #HealthEquity @YaleMed #Juneteenth #Cardiology

We were so happy to partner with participants on this decentralized, technology-enabled trial. Innovative way to do trials. I just wish the result had been better for patients. @VirusesImmunity @YaleMed @yalediscovers @TheLancetInfDis medicine.yale.edu/news-article...

Just published @TheLancetInfDis: PAX LC trial shows 15d of Paxlovid doesn't improve #LongCovid symptoms—but sets a new benchmark in decentralized, participant-centric clinical trials. Revolutionizing research accessibility! @VirusesImmunity @YaleMed www.thelancet.com/journals/lan...

Check out our new paper in the AGU GeoHealth journal @agugeohealth.bsky.social on increased risk of heart attack associated with higher ambient ozone pollution. This could not have been possible without my excellent mentor @hmkyale.bsky.social! @cchyale.bsky.social @yalesph.bsky.social

openRxiv is here! Excited to serve as a Board member of this independent nonprofit, supporting @biorxivpreprint.bsky.social and @medrxivpreprint.bsky.social. Ensuring rapid, open science stays accessible and researcher-driven. Join us: openrxiv.org #openRxiv #Preprints #OpenScience

openRxiv has arrived! We’re thrilled to announce the launch of openRxiv as an independent, researcher-led nonprofit to oversee bioRxiv and medRxiv, the world’s leading preprint servers for life and health sciences. openrxiv.org/introducing-... #openRxiv #OpenScience #Preprints #bioRxiv #medRxiv

📢 Our study: Short-term exposure to ozone linked to incr risk of heart attacks in younger adults, w/stronger effects in non-Hispanic Black patients. 🌍❤️ #Virgostudy Led: Siqi Zhang & Kai Chen. 🔗 Read more: agupubs.onlinelibrary.wiley.com/doi/full/10.... w/ @yalesph.bsky.social @yalemed.bsky.social

🌍 Cardiovascular science for a changing world The JACC Journals reaffirm our core mission: advancing global cardiovascular health through science, integrity, and humanity. Read more: www.jacc.org/doi/10.1016/... #Cardiology @jaccjournals.bsky.social

"Whatever happens, it is crucial for the research community, policymakers, & the public to engage in an open dialogue about how to balance fiscal responsibility with the need to maintain a robust and thriving research ecosystem." @hmkyale.bsky.social @academyhealth.bsky.social tinyurl.com/mtayf73x

🚀 Big news @JACCJournals! We’re embracing preprints to accelerate cardiovascular research & enhance collaboration. Check out our updated policy & streamlined @medrxivpreprint integration for faster more transparent science. 🧬 🔗Read more: authors.elsevier.com/a/1kaqe2d9GH... #OpenScience