For 47 years, Iranians have risen up thousands of times to reclaim the greatness they lost. In these final moments of their fight, stand with them as they take back their country's freedom. #IranRevolution #KingRezaPahlavi #IranRevolution2026 #DigitalBlackoutIran

Structural basis of modified ligand selectivity from N-terminal PAC1R alternative splicing pubmed.ncbi.nlm.nih.gov/41264251/ #cryoem

Yay! Our findings on the antidepressant drug vilazodone binding to the serotonin transporter (SERT) are out! We used cryo-electron microscopy and other advanced biophysics to provide data suggesting two high affinity binding poses. www.nature.com/articles/s41...

At some point, Doppio will replace relion's gui. Already you can do more in Doppio than in relion! 🤩

Frequent user of epitope tags? Try ours! IPI epitope tag antibodies & plasmids are now available through our partner @addgene.bsky.social! buff.ly/YEuZDIp

Our paper on SLC45A4 is out now in @nature.com! The orphan SLC45A4 transporter is a polyamine transporter involved in chronic pain signalling!

I am excited to share our latest preprint presenting the structure of human NHE6, a key endosomal Na⁺/H⁺ exchanger involved in Christianson syndrome. We bring together #cryo-EM, NMR, SAXS, lipidomics, and functional assays for an integrative analysis of NHE6 architecture, function, and regulation.

Check out this fascinating study on a fungal multipass translocon! What's really neat is how they did it: cryo-EM structure from the endogenously tagged and purified SND3 complex. It will be exciting to see if there is any potential for SBDD against fungi, Trypanosoma, and Leishmania (?).

We are excited to present the first #cryoEM structures of human GABA transporter 3 – GAT3 – bound to an in-house selective inhibitor, SR-THAP, to substrate GABA, and in the substrate-free state! @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

Yes, please. I go with Nemesis drones and like their motto "to see means to win": www.dronynemesis.cz/en.

Oh yeah, P-types ❤️💙💛 and the copper one, ATP7B! It was a great day full of science. Thank you so much everyone for being involved!

Thank you so much for guiding me on this amazing journey, @poulnissen.bsky.social, @charlottstock.bsky.social, and @tdieudonne.bsky.social. So great and thorough discussion with @melaniemcdowell.bsky.social, @henrietteautzen.bsky.social and Daan van Aalten. I highly appreciate your involvement.