Vlad Vyazovskiy
@vyazovskiy.bsky.social
π€ 255
π₯ 117
π 12
Sleep scientist
pinned post!
aeon.co/essays/how-a...
12 months ago
0
1
0
www.biorxiv.org/content/10.1...
loading . . .
Convergent Control of NREM Sleep and Anesthesia by Prefrontal Layer 5 Extratelencephalic Neurons
The cortical mechanisms governing the transition from consciousness to unconsciousness remain poorly understood. While most cortical neurons are suppressed during NREM sleep and anesthesia, we identif...
https://www.biorxiv.org/content/10.1101/2025.10.10.681639v1
30 days ago
0
3
1
reposted by
Vlad Vyazovskiy
Giulio Bernardi
about 1 month ago
Colombo et al., Plos Biology, "Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans"
journals.plos.org/plosbiology/...
loading . . .
Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans
Hemispherotomy is a neurosurgical procedure for treating refractory epilepsy by disconnecting a significant portion of the cortex. This study shows that the isolated cortex exhibits EEG patterns resem...
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3003060
0
11
6
reposted by
Vlad Vyazovskiy
Nigel Warburton
about 1 month ago
Sleep is very strangeβ¦
@aeon.co
aeon.co/essays/two-b...
loading . . .
Two billion humans are doing something bizarre right now: sleeping | Aeon Essays
It is our biggest blind spot, a bizarre experience that befalls us every day, and canβt be explained by our need for rest
https://aeon.co/essays/two-billion-humans-are-doing-something-bizarre-right-now-sleeping
2
17
4
aeon.co/essays/two-b...
loading . . .
Two billion humans are doing something bizarre right now: sleeping | Aeon Essays
It is our biggest blind spot, a bizarre experience that befalls us every day, and canβt be explained by our need for rest
https://aeon.co/essays/two-billion-humans-are-doing-something-bizarre-right-now-sleeping
about 1 month ago
0
1
0
reposted by
Vlad Vyazovskiy
Carissa VΓ©liz
about 1 month ago
Very nice to see my TEDx Porto talk is out! How
#privacy
can save your life. For more on privacy, get the
#book
- Privacy Is Power.
#AIEthics
www.youtube.com/watch?v=xSPR...
loading . . .
How privacy can saveΒ yourΒ life | Carissa VΓ©liz | TEDxPorto
YouTube video by TEDx Talks
https://www.youtube.com/watch?v=xSPRouBvgFE
3
65
43
pubmed.ncbi.nlm.nih.gov/41055995/
loading . . .
The locus coeruleus maintains core body temperature and protects against hypothermia during dexmedetomidine-induced sedation - PubMed
Activating the <i>adra2a</i> receptors of the brain's norepinephrine (NE) system produces NREM-like sleep and hypothermia. Dexmedetomidine (DEX), a selective Ξ±2 receptor (<i>adra2a</i>) agonist, is an...
https://pubmed.ncbi.nlm.nih.gov/41055995/
about 1 month ago
0
3
2
www.nature.com/articles/s41...
loading . . .
Psychedelic compounds directly excite 5-HT2A layer V medial prefrontal cortex neurons through 5-HT2A Gq activation - Translational Psychiatry
Translational Psychiatry - Psychedelic compounds directly excite 5-HT2A layer V medial prefrontal cortex neurons through 5-HT2A Gq activation
https://www.nature.com/articles/s41398-025-03611-0
about 1 month ago
0
2
1
reposted by
Vlad Vyazovskiy
ESRS
about 1 month ago
πππππ₯π’π§π ππ±πππ§πππ! Due to the high volume of requests, the deadline for Sleep Europe 2026 symposia submissions has been extended to 15 Oct 2025. This is your opportunity! Submit here:
https://esrs.eu/sleep-congress/symposia/
#ESRS
#SleepEurope2026
0
1
2
www.biorxiv.org/content/10.1...
loading . . .
Smartphone behavior is suppressed during bursts of wake slow wave
Real-world behavior unfolds as a continuous flow of actions over time. One possibility is that this continuous flow is enabled by a seamless stream of cortical activity. However, emerging evidence sug...
https://www.biorxiv.org/content/10.1101/2025.10.06.680725v2
about 1 month ago
0
1
0
reposted by
Vlad Vyazovskiy
Zoltan Molnar
about 2 months ago
The search for the mechanisms cortical regulation of sleep continues. Latest collaborative work suggests that part of the answer lies in the cortex. By switching cortical neurons on and off, we could change how much sleep animals got β and even the quality of that sleep.
doi.org/10.1101/2025...
add a skeleton here at some point
0
14
4
www.biorxiv.org/content/10.1...
loading . . .
Bidirectional modulation of sleep and wakefulness via prefrontal cortical chemogenetics
The drive to sleep is inescapable but its biological substrate remains largely elusive. Until recently, the search for sleep centres in the mammalian brain focussed on subcortical neurons that promote...
https://www.biorxiv.org/content/10.1101/2025.09.07.673922v1
2 months ago
0
8
6
reposted by
Vlad Vyazovskiy
Adriana Michalak, PhD
2 months ago
π ππΏπ²ππ΅ πΌπ³π³ ππ΅π² π£πΏπ²ππ: A comprehensive analysis examining the phenomenological boundaries between
#OutOfBodyExperience
and
#LucidDreams
has been published in our research topic "ππ―π₯π¦π³π΄π΅π’π―π₯πͺπ―π¨ ππ°π―π΄π€πͺπ°πΆπ΄ ππΉπ±π¦π³πͺπ¦π―π€π¦ π₯πΆπ³πͺπ―π¨ πππ¦π¦π±". π§
#ConsciousnessResearch
www.frontiersin.org/journals/psy...
loading . . .
Frontiers | Distinguishing out-of-body experiences from lucid dreaming: a phenomenological analysis
Despite extensive discussions, a consensus is lacking on whether out-of-body experiences (OBEs) and lucid dreams (LDs) should be considered as distinct categ...
https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2025.1600707/full
0
2
1
reposted by
Vlad Vyazovskiy
SPACE Lab
2 months ago
π§ The official website of the Neuroscience of Dreaming Summer School (4β8 May 2026, IMT School, Lucca, Italy) is now live:
nodsummerschool.imtlucca.it
π Check out the confirmed speakers + our program overview. Detailed schedule and registration coming soon!
0
12
6
reposted by
Vlad Vyazovskiy
Bryan Roth
4 months ago
in the spirit of the recent
#psychedelic
GRC which is heretofore known as the 'WOODSTOCK OF PSYCHEDELIC SCIENCE' I propose a new definition in which every psychedelic is 'classical'!!
open.substack.com/pub/zendudes...
loading . . .
A proposed classification of psychedelics
"Move over Beethoven"
https://open.substack.com/pub/zendudest/p/a-proposed-classification-of-psychedelics?r=g3vpk&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
2
10
7
reposted by
Vlad Vyazovskiy
Devin Effinger, Ph.D
4 months ago
The inaugural
#GRCPsychedelics
was a success! I am honored to have been one of a few chosen to receive a travel award and be able to share the stage with the leaders in the field. π to the organizers!
@alexkwan.bsky.social
@vyazovskiy.bsky.social
@melissaherman.bsky.social
@viditavaidya.bsky.social
3
34
9
reposted by
Vlad Vyazovskiy
Alex Kwan
4 months ago
We worked so well as a team for the
#GRCPsychedelics
@vyazovskiy.bsky.social
@viditavaidya.bsky.social
@melissaherman.bsky.social
and congrats to
@theborislab.bsky.social
and
@mikaelpalner.bsky.social
, who will be the future vice-chairs!
1
31
10
reposted by
Vlad Vyazovskiy
Scott Thompson, PhD
4 months ago
Thank you
@alexkwan.bsky.social
@melissaherman.bsky.social
@vyazovskiy.bsky.social
add a skeleton here at some point
0
0
1
reposted by
Vlad Vyazovskiy
Alex Kwan
5 months ago
Canβt believe
#GRCPsychedelics
is happening in two weeks! We reached capacity attendance β sorry we could not accommodate everyone. We look forward to seeing many of you at the meeting. w/
@vyazovskiy.bsky.social
@viditavaidya.bsky.social
@melissaherman.bsky.social
2
32
19
reposted by
Vlad Vyazovskiy
Charlotte Boccara
5 months ago
also see here:
esrs.eu/event/frm-20...
loading . . .
FRM 2025 satellite workshop on Integrative Sleep Research β OSLO | ESRS
A workshop satellite to the FENS regional meeting in Oslo to foster collaborations and tools development from system/molecular neuroscience to sleep researchers
https://esrs.eu/event/frm-2025-satellite-workshop-on-integrative-sleep-research-oslo/
0
0
1
reposted by
Vlad Vyazovskiy
Charlotte Boccara
5 months ago
ππ§ π€Join us on June 20th, 2025, in Oslo for a workshop that bridges System Neuroscience and Sleep Research in partnership with
@esrs.bsky.social
@ncmbm.bsky.social
@sainsburywellcome.bsky.social
@uio.no
@KU A satellite of the FENS regional meeting, register here:
frm2025oslo.no/basic-sleep-...
3
13
10
reposted by
Vlad Vyazovskiy
Giulio Bernardi
6 months ago
One month left to apply!
#phdpositions
,
#phdopportunities
,
#sleep
,
#dreams
,
#brain
,
#neuroscience
0
1
1
reposted by
Vlad Vyazovskiy
Heart Rhythm Club
8 months ago
The Heart Rhythm Club is a student-run society providing a platform for students to explore the various aspects of cardiovascular sciences through seminars and discussions with world-leading scientists.
0
0
1
Deficient synaptic neurotransmission results in a persistent sleep-like cortical activity across vigilance states in mice: Current Biology
www.cell.com/current-biol...
loading . . .
Deficient synaptic neurotransmission results in a persistent sleep-like cortical activity across vigilance states in mice
Using a mouse model of altered neurotransmission (Vamp2rlss), Guillaumin etΒ al. show that differences typically observed between vigilance states in neural dynamics and spectral signatures can be mark...
https://www.cell.com/current-biology/fulltext/S0960-9822%2825%2900267-2
8 months ago
1
10
2
reposted by
Vlad Vyazovskiy
Natalie hauglund
10 months ago
New preprint now online!
www.biorxiv.org/content/10.1...
We created an algorithm to detect NREM sleep micro-arousals and used it to re-analyze LFP data from the motor cortex of sleeping mice π€ This is what we found:
loading . . .
https://www.biorxiv.org/content/10.1101/2025.01.29.635246v1.full.pdf
1
5
4
reposted by
Vlad Vyazovskiy
Matt Wall
10 months ago
We lost one of the absolute all-time greats. π’
add a skeleton here at some point
1
12
2
reposted by
Vlad Vyazovskiy
Thomas Andrillon
11 months ago
I co-edited a special issue on dreaming and mind wandering for
@phimisci.bsky.social
The first papers are now online. Check them out! And don't hesitate to follow/read this amazing, free & open access journal! π¬π§ π€π
add a skeleton here at some point
1
29
15
reposted by
Vlad Vyazovskiy
Ben BrΓ©ant
12 months ago
"Paradoxical wake" archive paper update, with new content & new prospects π§ͺπ§ We show global slow waves after psychedelic administration + eye monitoring of freely-moving mice! A thrilling project with
@vyazovskiy.bsky.social
&
@oxforddpag.bsky.social
#EEG
#sleep
www.biorxiv.org/content/10.1...
loading . . .
Sleep-like state during wakefulness induced by psychedelic 5-MeO-DMT in mice
Psychedelics lead to profound changes in subjective experience and behaviour, which are typically conceptualised in psychological terms rather than corresponding to an altered brain state or a distinc...
https://www.biorxiv.org/content/10.1101/2022.12.11.519886v2
0
9
1
Sleep-like state during wakefulness induced by psychedelic 5-MeO-DMT in mice:
www.biorxiv.org/content/10.1...
loading . . .
Sleep-like state during wakefulness induced by psychedelic 5-MeO-DMT in mice
Psychedelics lead to profound changes in subjective experience and behaviour, which are typically conceptualised in psychological terms rather than corresponding to an altered brain state or a distinc...
https://www.biorxiv.org/content/10.1101/2022.12.11.519886v2
12 months ago
1
14
2
www.jobs.ac.uk/job/DKV641/p...
12 months ago
0
0
0
wpi-iiis.tsukuba.ac.jp/news/2757/
12 months ago
0
0
0
reposted by
Vlad Vyazovskiy
Alex Kwan
12 months ago
How to get your psychedelic research proposal funded? π
@sofiyahupalo.bsky.social
(NIMH) and Tanya Ramey (NIDA) will hold an informal panel to discuss institute goals and funding priorities at the
#GRCPsychedelics
7/13-7/18/2025 Registration for the meeting is open -
www.grc.org/neurobiology...
2
44
12
reposted by
Vlad Vyazovskiy
Anil Seth
12 months ago
Very impressive βImaginariumβ venue for XPANSE 2024. Iβm excited to be on stage there later (~12:45pm local time) to talk about consciousness and AI. And there are some (signed, of course) books for sale too :).
www.xpanse.world
0
15
1
reposted by
Vlad Vyazovskiy
josh hardman
12 months ago
Effects of different psychoactive drugs on apical dendritic spines of cortical pyramidal neurons in mice. From
@claraliao.bsky.social
,
@alexkwan.bsky.social
, et al.
www.nature.com/articles/s41...
0
8
3
reposted by
Vlad Vyazovskiy
Ben BrΓ©ant
12 months ago
An excellent read on hibernation from Vlad Vyazovskiy, and thoughts provoking as per usual!
aeon.co/essays/how-a...
loading . . .
How animals learned to hibernate and why we canβt do it (yet) | Aeon Essays
Hibernation allows many animals to time-travel from difficult times to plenty. Could humans learn how to do it too?
https://aeon.co/essays/how-animals-learned-to-hibernate-and-why-we-cant-do-it-yet
3
8
7
aeon.co/essays/how-a...
12 months ago
0
1
0
www.pnas.org/doi/10.1073/...
about 1 year ago
0
0
0
you reached the end!!
feeds!
log in