New degrader paper using the immunoproteasome. Congrats Cody Loy and Tim Harris! pubs.acs.org/doi/full/10....

Paper Drop! Rpn-13 is the best protein :) pubs.acs.org/doi/10.1021/...

ByeTACs is finally out in J. Med Chem. Congrats team! Can't wait to see how else we can use this degradation technology. @codyloy.bsky.social pubs.acs.org/doi/10.1021/...

So happy to finally see this out! Check out our paper on identification of a small molecule inhibitor of RGS2 protein degradation! Thanks to all the authors for your hard work! www.sciencedirect.com/science/arti...

A friend drove two hours today for her breast cancer chemotherapy only to learn it was canceled due to NIH cuts. Clinical trial ended midstream. No treatment, no restart, no plan, no information. Her bro-in-law's chemo was also canceled.

Congratulations Breanna Zerfas and teams at DFCI on this linkerless PROTAC degrading and ER-stress transmembrane protein IRE1α with CRBN! pubs.rsc.org/en/content/a...

Really proud to have this out in J Med Chem! Congrats to Christine and @codyloy.bsky.social pubs.acs.org/doi/10.1021/...

Can it be done?!??!?!

New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024. That's not to mention the countless lives that biomedical research has saved. Show me a better investment than that. www.forbes.com/sites/michae...

UC Irvine

I got laid off today, with the rest of 18F. 18F was an elite federal software shop. We made gov't websites work better, more efficiently for the American people. We saved taxpayers from getting screwed over by contractors. And were fired for it. We made this website to tell our story: 18f.org

Host and pathogen aficionados: Join us in Blois!- registration deadline 1st March- Please RP- meetings.embo.org/event/24-hos...

Trump's illegal NIH cuts mean cancer researchers would be laid off, sick kids going without treatment, and more. These cuts would be DEVASTATING for lifesaving research. Some Republicans have said they agree—but they just blocked my amendment to reverse Trump's NIH cuts anyway.

Some good news: applications are open for the Weill Institute Emerging Scholars Symposium @ Cornell! Senior PhD students and, now, postdocs interested in networking & presenting their work in cell & molecular biology at Cornell should apply by Apr 14. Please repost! wicmb.cornell.edu/emerging-sch...

The Democrats on the House Science Committee have set up a website to collect stories from fired federal employees, anonymously if desired democrats-science.house.gov/sciencefirings

Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence

Black chemists you should know about: These inventors, educators, and unsung heroes changed lives through their work in chemistry. cen.acs.org/people/profi... #BlackinChem #BlackHistoryMonth #chemsky🧪

Donald Trump and Elon Musk’s idea of efficiency is stopping research on curing cancer.

The Arthur C. Cope Postdoctoral Fellowship is a 2 year program designed to recognize outstanding achievements and foster innovative research in organic chemistry in the U.S. Fellows will receive $85,000 annually. Nominations are open until April 1. zurl.co/81b5j

If you would like to see how much economic activity and grants and how many people are employed through NIH in your state, just use this handy website. And then contact your Congressional Rep and tell them to prioritize NIH. www.unitedformedicalresearch.org/nih-in-your-...

Hello Bluesky friends! I am a #newPI starting at UC Irvine in April, interested in gene regulation and functional genomics in stem cell models of development (esp neural crest). We are hiring at all levels – please reach out/spread the word! sskimlab.org

The DOC Graduate Research Symposium (GRS) will take place at the San Diego State University July 17-20, 2025. Graduate students get to interact with leaders from academia, industry, funding agencies and publishers. Applications are due on March 11th zurl.co/rBH7y

Starting 2025 off with a review about degrons in @rscmedchem.bsky.social. Congrats Tim! pubs.rsc.org/en/content/a...

Save the Date for the Inaugural DOC-EWOC Virtual Symposium on January 8th, 2025 @3pm EST featuring Professor Seunghyun Sim! @organicdivision.org Watch for free at: YouTube: orgn.link/watch Zoom: orgn.link/vs-zoom Thank you to @BeyondCCHF for hosting #ChemSky

New #ChemBioChem paper by the @traderlab.bsky.social: "Synthesis and Application of a Versatile Immunoproteasome Activity Probe" chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

Can colleagues amplify this appeal to journals and journal editors to open accounts on Bluesky, please? @MicrobioSoc @TrendsMicrobiol @CellCellPress @JBacteriology @jbiolchem @Nature @ScienceMagazine @PNASNews @MolMicroEditors @NAR_Open @NatureMicrobiol @NatureComms @ASMicrobiology 🙏 🦠🧪🧫🧬

Thanks @blakerpeterson.bsky.social for giving an awesome seminar today #UCIPharmSci. Pacific blue dye for the win!