Ruxandra Teslo
@ruxandrabio.bsky.social
đ€ 1592
đ„ 80
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Biologist
reposted by
Ruxandra Teslo
Saloni
3 days ago
New post! It may seem ambitious to ask for individual patient data from clinical trials to be shared, anonymized, for use by other researchers. But the history of medicine shows us that clinical trials have already undergone a series of transformations that once seemed equally bold:
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Clinical trial reforms that once seemed radical
How randomized controlled trials, preregistration, and results reporting became standard practice.
https://www.clinicaltrialsabundance.blog/p/clinical-trial-reforms-that-once
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My new essay on why the modern world is so preoccupied with equality and oppression. In a secular age, they often function as a form of consolation. When transcendence recedes, the "non-winners" lose the dignity once grounded in a divine, cosmic order.
www.writingruxandrabio.com/p/equality-a...
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Equality as a Consolation Prize
In a secular world, equality is a last attempt to offer some dignity to the weak
https://www.writingruxandrabio.com/p/equality-as-a-consolation-prize
3 days ago
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reposted by
Ruxandra Teslo
Frank Harrell
4 days ago
Amazingly thought provoking from
@ruxandrabio.bsky.social
:
substack.com/home/post/p-...
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Equality as a Consolation Prize
In a secular world, equality is a last attempt to offer some dignity to the weak
https://substack.com/home/post/p-189746201
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reposted by
Ruxandra Teslo
Everybody Gets Pie
11 days ago
Abundance, but for research? New drugs are taking a long time to reach the market, in part because of how long clinical trials take.
@ruxandrabio.bsky.social
explains Australia's model, which makes early clinical trials easier and how it's leading everyone to move their trials there.
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Abundance, But Make It ~Science~
YouTube video by Everybody Gets Pie
https://www.youtube.com/shorts/QJfGg35KEo4
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reposted by
Ruxandra Teslo
Saloni
19 days ago
The FDA recently published guidance on Bayesian statistics in clinical trials. If there's one thing you read about it, let it be this great post by Adam Kroetsch:
www.clinicaltrialsabundance.blog/p/will-bayes...
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reposted by
Ruxandra Teslo
Saloni
26 days ago
NEW BLOG! Ruxandra Teslo
@ruxandrabio.bsky.social
, Adam Kroetsch, Manjari Narayan
@neurostats.org
, Witold WiÄcek and I have started a joint blog on clinical trial reform. We'll aim to publish weekly on how to make clinical trials more efficient. Subscribe:
clinicaltrialsabundance.blog
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Ruxandra Teslo
hilzoy
24 days ago
This is a really good post. Itâs worth reading even if youâre not a health research geek. I find it incredibly useful when someone gives me a sense of how stuff works in a field I am not familiar with, at least not on a suitably granular level, and this post does that.
add a skeleton here at some point
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reposted by
Ruxandra Teslo
Saloni
24 days ago
Great post
@ruxandrabio.bsky.social
on FDAâs refusal to review Modernaâs flu vaccine, changing its position on what trial design was acceptable. Regulatory uncertainty doesnât just mean missing out on this vaccine, but also reduces future R&D investment:
clinicaltrialsabundance.blog/p/the-modern...
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In 2023, papers denying motherhoodâs role in the gender wage gap went viral. I called out their flawed assumptions then, and newer results have proven me right.
www.writingruxandrabio.com/p/of-course-...
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Of course motherhood drives the gender wage gap
Discussions around the motherhood wage gap reveal the limits of autism and the benefits of female intuition
https://www.writingruxandrabio.com/p/of-course-motherhood-drive-the-gender
3 months ago
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reposted by
Ruxandra Teslo
Anne with an âeâ
12 months ago
Plus remote or hybrid work. Itâs a game changer for us mums who also work outside the home.
add a skeleton here at some point
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Many women face a choice between career advancement and motherhood. But emerging technologies could allow women to have it all. All in this piece on how the gender pay gap arises & fertility tech đ§”
worksinprogress.co/issue/fertil...
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Fertility on demand - Works in Progress
Many women face a choice between career advancement or motherhood. But emerging fertility technologies could allow women to have it all.
https://worksinprogress.co/issue/fertility-on-demand/
12 months ago
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reposted by
Ruxandra Teslo
Frank S. David
12 months ago
A+ piece by
@ruxandrabio.bsky.social
. IMHO she is one of the sharpest writers about bio today!
worksinprogress.co/issue/fertil...
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Fertility on demand - Works in Progress
Many women face a choice between career advancement or motherhood. But emerging fertility technologies could allow women to have it all.
https://worksinprogress.co/issue/fertility-on-demand/
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reposted by
Ruxandra Teslo
Kumar Garg
about 1 year ago
Worth a read. I was excited to support this workshop by
@ruxandrabio.bsky.social
and Willy alongside
@ifp.bsky.social
, and eager to help more of these reform ideas get traction in 2025.
add a skeleton here at some point
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reposted by
Ruxandra Teslo
Frank S. David
about 1 year ago
Balanced piece by David Wallace-Wells in NYT on the discovery of Ozempic, etc., based on Jeff Flierâs oral history from over the summer. (And as a bonus, it cites
@ruxandrabio.bsky.social
& Willy Chertmanâs great new piece on âclinical trial abundanceâ too!).
www.nytimes.com/2024/12/25/o...
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Opinion | We Could Have Had Ozempic Nearly 40 Years Ago (Gift Article)
Researchers identified one key breakthrough for GLP-1 drugs in the 1980s, but Pfizer walked away.
https://www.nytimes.com/2024/12/25/opinion/ozempic-weight-loss-pfizer-diabetes.html?unlocked_article_code=1.kE4.brH7.1yVL9hyzlDsx&smid=nytcore-ios-share&referringSource=articleShare
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Can preset rules inoculate us against misinformation? Contrary to some, I believe not. I discuss this & the risks of using 'scientific evidence' for top-down information control in my post "Misinformation studies &The Road to Mental Serfdom"
www.writingruxandrabio.com/p/the-road-t...
about 2 years ago
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Is egg freezing the future when it comes to extending the female reproductive window? In this piece, I look at the scientific evidence for the potential of this procedure in the preservation of female fertility:
www.writingruxandrabio.com/p/is-egg-fre...
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Is egg freezing the future? A cold look at the data
I perceive the extension of female reproductive lifespan as one of the most significant and potentially rewarding pursuits in biomedical research. Is oocyte cryopreservation a viable strategy?
https://www.writingruxandrabio.com/p/is-egg-freezing-the-future-a-cold
over 2 years ago
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reposted by
Ruxandra Teslo
Ted Underwood
over 2 years ago
It's not quite Follow Friday yet, but what the hell, here's a short list of people who joined bsky recently and who tend to discover interesting things. Follow them â connect the nodes!
@marcwatkins.bsky.social
@ruxandrabio.bsky.social
@dasmiq.bsky.social
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Did aristocratic women play an outsized role in the spread of Christianity in the Late Roman Empire? The consensus view is Yes. But Michele Salzman says No. I had fun writing this piece analysing her arguments:
www.writingruxandrabio.com/p/did-aristo...
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Did aristocratic women drive the rise of Christianity? Michele Salzman says No
Summary of arguments against the consensus view that aristocratic women were key to the rise of Christianity in the Late Roman Empire. Based on "The Making of a Christian Aristocracy" by M. Salzman
https://www.writingruxandrabio.com/p/did-aristocratic-women-drive-the
over 2 years ago
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Some things are cultural: female babies were left to die of exposure in Ancient Roman times. This would be unconceivable today! In this piece I reply to comments on my previous post abt the role of aristocratic women in the spread of Christianity
open.substack.com/pub/ruxandra...
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Some things are cultural: A response to comments on my last piece
This is a short post where I respond to some of the people who were not convinced by my previous piece. The gist of that piece is that the role of aristocratic women in the rise of Christianity in the...
https://open.substack.com/pub/ruxandrabio/p/some-things-are-cultural-a-response?r=b0xdg&utm_medium=ios&utm_campaign=post
over 2 years ago
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Did aristocratic women play an outsized role in the spread of Christianity in the Late Roman Empire? The consensus view is Yes. But Michele Salzman says No. I had fun writing this piece analysing her arguments:
open.substack.com/pub/ruxandra...
over 2 years ago
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I can post selfies here without feeling cringe
almost 3 years ago
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We need to get bowser on BlueSky
almost 3 years ago
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Has this person lived in the real world ? đ
almost 3 years ago
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Maybe I can use Bluesky for shitposting and twitter for interacting with professional ppl. I hope the 2 worlds donât merge
almost 3 years ago
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Countries that use ârecriprocal kinshipâ (mother calling her kid âmomâ). To be clear, in Romania this can only be done in a specific noun case (vocative), which is used to address ppl. Eg âplease mom, do thisâ
almost 3 years ago
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