🚨🚨New paper out in @natcomms.nature.com!! Come for the first large-scale analysis of plasmid copy number across species, stay for one of the most intriguing results of my lab: universal scaling laws in plasmid biology! 📈🧬 👉 www.nature.com/articles/s41...

Johannes Stein @jmstein.bsky.social from Harvard/Wyss reports impressive work on imaging the nuclear ultrastructure of cells using cryosections and DNA-PAINT #SMLMS2025

Ever wondered where cargo travels through the central channel of the NPC? Siegfried Musser lab @musser-lab.bsky.social measured that in living cells using MINFLUX. Fascinating data! #SMLMS2025

I'm excited to share the preprint of my PhD work from @musser-lab.bsky.social on understanding the structure and dynamics of FUS condensates at the nanoscale. We’ve used different single-molecule microscopy techniques, including MINFLUX, to understand FUS condensate behavior.

There is still time to apply to become part of our team at Nature Biomedical Engineering! Please share! springernature.wd3.myworkdayjobs.com/SpringerNatu...

🚨New preprint from the lab🚨 🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK. www.biorxiv.org/content/10.1...

Cool new technique from @jmstein.bsky.social ! Great way to get the precision of DNA-PAINT away from the coverslip!!

(1/n) DNA-PAINT imaging inside the nucleus at single antibody resolution using TIRF? Ultrathin sectioning makes it happen! Grateful to share my postdoctoral work introducing “tomographic & kinetically-enhanced DNA-PAINT” or in brief: tkPAINT. Out in @pnas.org! doi.org/10.1073/pnas... 👇🧵

Looking forward to sharing our research with the IDP community tomorrow!

Paper visualizing traffic through nuclear pores unlocks the full potential of #MINFLUX: 2-color 3D tracking with sub-ms time resolution and single-digit nm localization precision 💪 Congrats @abhishek-sau.bsky.social, @musser-lab.bsky.social, @thebioguy.bsky.social, @EMBL, et al! #SMLM #nuclearpore

Our work on resolving nuclear transport using MINFLUX is finally out! Great work from Sig, Abhishek and all the coauthors. Thrilled to have had the opportunity to be a part of it!