1/n #football #thfc I am always intrigued by the timing etc of the sacking of English Premier League football managers. Thomas Frank was sacked today presumably for severely under performing. I would say his squad is no better than the squad from last year.

A pardon does not change a guilty verdict to a not guilty verdict.

Listening to a talk about digital biomarkers and the concept of screening for pre-diabetes is being discussed!

What an odious racist.

I have heard about Claude Code. My first Q; what does it do? The 'overview' website seems an obvious starting place. Apparently it "is an agentic coding tool that reads your codebase, edits files, runs commands, and integrates with your development tools". I am none the wiser.

He's not bright enough to work out that that is how the stock market works today. Everything he does is bad news.

#WinterOlympics These team events like team ski jumping should be taken from the schedule. Ski jumping is not a team sport.

1/2 The one publication reporting sensitivity was based on just 200 (approx) stage 1 cases from multiple cancer types, so the sensitivity for any given type is poorly estimated. Overall just 40% sensitivity for stage 1 (based on cross-valdation as no independent data set).

I find drug advertising on US TV distasteful enough. But advertising a 'screening' test for which there is no evidence of benefit is even worse. Encapsulates the driving force behind all our current problems, i.e. the primacy of commercial interests above all else.

💯 percent

I have thought for years that a computer ought to be very good at taking a medical history and, on that basis, make a differential diagnosis and order relevant tests. The medical exam is overrated. (Hands on healing does have a role).

www.theguardian.com/us-news/2026... Inveterate liar seems to be a required characteristic of the key individuals running this authoritarian ship. They lie in order to enable their actions to harm the population economically and physically.

www.theguardian.com/commentisfre... "What has really gone too far is these people's immunity".

Absolutely

I wanted to marry my English teacher when she got out of jail.. But apparently you can’t end a sentence with a proposition.

Ludicrously inadequate response from the publishers @wolterskluwer.com A paper such as this should a) never get close to being published and b) when its problems are pointed out it should be retracted immediately.

Yeah, but, the economy.

Simply wonderful.

Genius

Shameful.

www.theguardian.com/commentisfre... Powerful stuff, cogently argued.

The USA Team from the cricket T20 World Cup. Diversity rules.

www.bbc.com/news/article... Another day and another action that ten years ago would have cost the President his job. (The excuse that it was a WH staffer does not hold water).

I wish the media would stop describing these shitheads as elites. The word implies superior in some way - they are not superior, they are inferior in most ways that matter, they are simply entitled privilege because they have money.

Want to hear a bluegrass cover of Dire Straits' Money for Nothing? Of course you do.

Die, Dichotomy. www.linkedin.com/pulse/die-di... A brief post encouraging you to read the original paper with @erik-van-zwet.bsky.social and @f2harrell.bsky.social . onlinelibrary.wiley.com/doi/epdf/10....

WTAF www.bbc.com/sport/articl...

My locale, but I only scored 83%

At lunch in a pub in Suffolk (eat out to help out) and a loud Griff Rhys Jones was at the next table name dropping to his companions. My wife said to me (also loudly) "I expect next week he'll be telling his friends about the time he sat next to a famous lawyer and genetic epidemiologist".

I'm reasonably certain someone in the US hierarchies of power will express some odious opinion.

The first "taster" quiz under Brazil is up birdbrainer.app ! I'm hoping to get a couple more done today 🤞 #birdbrainerapp #birdsoftheworld #birds

📻 Bumper show tomorrow, 4-6pm, wxdu.org or 88.7FM locally, with so much new music, old, new, & archival! I'll spin Jane Weaver's The Fallen By Watch Bird (15th anniversary edition), electrifying post-punk from Dry Cleaning, retro UK library music from Lee Mason, claire rousay's 3rd album, & more!

Extensive quantitative information of the side effects of various treatment options also available at side-effects.breast.predict.cam based on work a by @alexandrafreeman.bsky.social and colleagues.

So what music genres do different scientific fields map to.

@gavinyamey.bsky.social I think you might give it a go. Global PH the jazz-funk of academia.

www.theguardian.com/commentisfre... Well worth a read.

Brilliant novel.

I have wondered whether the extent of the ties between Epstein and academia are due, in part, to the funding system in the USA. Academics salaries are directly linked to their ability to raise funding and so academics will explore all possible options and may turn a blind eye to any problems.

1/2 Our paper on immune infiltration and breast cancer prognosis is finally published www.cell.com/iscience/ful... We used immunohistochemistry to profile >12,000 breast tumours. Too many collaborators to mention. The work was part of the EU Horizon 2020 funded B-CAST project.

This week's bird photo offering; a southern yellow-billed hornbill. #birds #birdsoftheworld #nature

Has the USA ever had a culture of shame? It seems to me that (apparent) success in the world of business/money making has always excused all sorts of undesirable character traits. Trump being the poster child.

Please play tug-of-war/fight-to-the death

Why does it seem wrong to wash tablets down with an alcoholic drink? (Metformin for the record).

Proud to have been involved in the design of Predict (Breast & Prostate) to make sure that its results are clear and easy for patients and professionals to understand. Fantastic to see how many people it has helped.

If you see people with breast cancer, into evidence based healthcare and shared decision making, this tool is for you.

And this is the map of web sessions by country.

I've finally been published in Nature...sort of! Amazing review of my book "Bad Influence". "Her deeply reported, compelling analysis lays bare how social-media influencers, apps, algorithms and the rest of the digital ecosystem are transforming our health" www.nature.com/articles/d41...

Condolences to nearly everyone in ecology and evolution today on your grant rejection!

The term "the elite" has been high-jacked. Elite means superior in abilities/qualities and should only be domain specific; elite athletes, elite academics etc. Calling rich people "the elite" just because they are rich seems inappropriate - they are no necessarily superior in terms of any ability.

The PREDICT breast web tool is now fifteen years old. breast.v3.predict.cam It is free to use. The tool has been used over 4 million times. If you'd like to sponsor the costs of web site maintenance or ongoing development send me a DM. #breastcancer