New preprint out! We present a global optimization metaheuristic that performs exceptionally well on tough model calibration problems in systems biology.

Host-aware Identification of Intrinsic Gene Expression Biopart Parameters from Combinatorial Libraries doi.org/10.64898/202...

Interested in microbial ecology? Our latest paper, “Identification of dynamic models of microbial communities: A workflow addressing identifiability and modeling pitfalls,” is now out in PLOS Computational Biology journals.plos.org/ploscompbiol... .

every company in 2025

The guy who got famous betting against the housing market in 2007 just before that bubble burst - played by Christian Bale jn “The Big Short” - just wagered $1 billion on the collapse of the AI boom. www.wsj.com/livecoverage...

👉 New paper out: "Generalized Inverse Optimal Control and Its Application in Biology" Joint work with Sebastian Sager — www.mathopt.de/people/sager/ Just published in 𝗔𝗡𝗡𝗨𝗔𝗟 𝗥𝗘𝗩𝗜𝗘𝗪𝗦 𝗜𝗡 𝗖𝗢𝗡𝗧𝗥𝗢𝗟 👉 Link: authors.elsevier.com/sd/article/S... Optimality principles directly from observations!

Free access to this article at authors.elsevier.com/a/1lVrl8jbph...

🚀 New Paper Published! 📄 Title: "Mechanistic dynamic modelling of biological systems: the road ahead" 📄 Journal: Current Opinion in Systems Biology 🔗 doi.org/10.1016/j.co... This is review/opinion paper co-authored with Alejandro F. Villaverde afvillaverde.webs.uvigo.gal

🚨 New preprint out! 🚨 Our latest work discusses the complexities of mathematically modelling microbial communities. Joint work with Ana Paredes and @balsacanto.bsky.social 🔬 doi.org/10.1101/2025... #Microbiome #Ecology #Modeling

🚨 New paper out! Novel algorithms for uncertainty quantification in systems biology using conformal inference. Joint work with Alberto Portela and Marcos Matabuena www.marcosmatabuena.com 📄 Read more: doi.org/10.1371/jour... #SystemsBiology #UQ

🚀 @bcbhubcsic.bsky.social l is pleased to share the recorded seminars from April 2! 🎥 Watch the presentation of the tool pyDock by juanfdezrecio.bsky.social (ICVV) & MEIGO by @julio-r-banga.bsky.social @mbgcsic.bsky.social 📺 Available now 👉 pyDock youtu.be/yvH8-1kg94Y 👉MEIGO youtu.be/T68sGGf2N9c

Fully-funded PhD opportunity in mathematical biology and applied mathematics with Pascal Buenzli and me at Queensland University of Technology in Brisbane, Australia. Details at smb.org/Member-Forum... @smbmathbiology.bsky.social

Lungfish xkcd.com/3064

I shared a controversial take the other day at an event and I decided to write it down in a longer format: I’m afraid AI won't give us a "compressed 21st century" Here: thomwolf.io/blog/scienti... It's an extension of this interview discussion from the AI summit: youtu.be/AxBd3G0lFLs?...

Today marks the beginning of OpenRxiv, which replaces bioRxiv and medRxiv, the world's largest preprint platform for life and medical science openrxiv.org/introducing-... @openrxiv.bsky.social

How gut microbiome research needs to move forward. Going multi-omics, getting to causality, rigorous clinical studies www.cell.com/cell/fulltex... @cellpress.bsky.social

RNA xkcd.com/3056

You first.

Sputnik moment?

"A call for research to address the threat of paper mills" Paper mills are an increasing threat to the integrity of the scientific record. This Perspective discusses 5 key questions that need resourcing & support #PLOSBiology journals.plos.org/plosbiology/...

Wordcloud of our research interests

If your profile says invalid handle, here is how you fix it

Over at her blog, @pawlean.com talks about why she is using BlueSky and I find that so many of her reasons resonate with me www.pawlean.com/posts/why-im...

Librarians moving dystopian novels to the nonfiction shelves.

Hello everyone! 🌟 I am a researcher in computational systems biology. I look forward to sharing thoughts, ideas, and keeping in touch with all of you in this fresh space. Let’s keep the conversation going!