Important paper rebutting prior findings. "Thymectomy in adults with small or localized thymomas was not associated with increased 5-year mortality or cancer death." from @yalecancer.bsky.social in @iaslc.bsky.social JTO www.jto.org/article/S155...

Read the Dekleptocracy substack: "When a phantom foundation with no address, no registration and a founder who might not exist, wires $100 million to the president's crypto company, America has a problem" dekleptocracy.substack.com/p/trumps-she...

Appropriately critical commentary on cochrane reviews as the apply to matched targeted therapy by @viveksubbiah.bsky.social Journal of Clinical Oncology ascopubs.org/doi/full/10....

Just a reminder that the head of the NIH was up on stage today as Trump spewed item after item that science has already convincingly demonstrated are false. And he has done nothing to get the American public more accurate information.

Things today's White House autism announcement did not do: -Discuss strategies to increase supports and services for autistic people/families -Highlight why autistic people and families deserve respect, not pity or fear -Endorse one speck of autism research that is not dangerous pseudoscience

in retrospect, it was a mistake to teach algebra and geometry but not "statistics for everyone" in high school we are drowning in lies, partly because we never learned to swim

Brief Report: Critical Role for DNA-Based Sequencing in Discriminating Distinct Primary Lung Cancers with Different MET Exon 14 Skipping Mutations. www.jto.org/article/S155... This study evaluated NSCLC cases with MET exon 14 skipping (METex14) mutations

Paracetamol remains an important option to treat pain or fever in pregnant women. Following rigorous assessment of the available scientific data, we find no evidence that taking paracetamol during pregnancy causes autism in children. Read more 👉 www.ema.europa.eu/en/news/use-...

Realized the link above didn't work: public-inspection.federalregister.gov/2025-18510.pdf

This is bonkers. FDA is going to change leucovorin's label based on a lit review with data on 40 patients w/ cerebral folate deficiency and comparisons to "known natural history." www.statnews.com/2025/09/22/f...

Medical ethicist Arthur Kaplan, quoted in the NYT: “The announcement on autism was the saddest display of a lack of evidence, rumors, recyling old myths, lousy advice, outright lies & dangerous advice I have ever witnessed by anyone in authority in the world claiming to know anything about science”

I didn’t watch and won’t, but today’s acetaminophen farce is exponentially worse than that infamous press conference about bleach and UV light, because of those who stand next to him they are destroying the institutions that made American science and medicine worthy of our hopes and trust

Appropriate policy by JTO to fight the flood of AI-driven letters to the editor. Artificial Intelligence, Ghost Writers, and Scientific Integrity - Journal of Thoracic Oncology www.jto.org/article/S155...

Useful trial shows value of supportive measures for amivantamab tolerance (doxycycline or minocycline, clindamycin, chlorhexidine (on nails), and ceramide-based moisturizer www.jto.org/article/S155...

nice review covering the topic of synthetic lethal approaches to cancer therapeutics in @natrevdrugdiscov.nature.com rdcu.be/eHDAK

Moving story by @drsgraff.bsky.social Brown Paper Bags | Journal of Clinical Oncology ascopubs.org/doi/full/10....

Paper on sunvozertinib in EGFR exon 20 insertions out in @ASCO JCO. 46% response rate for 200 mg dose. Now FDA approved, but can't seem to get the drug for patients ascopubs.org/doi/full/10....

Appropriately critical commentary on cochrane reviews as the apply to matched targeted therapy by @viveksubbiah.bsky.social Journal of Clinical Oncology ascopubs.org/doi/full/10....

First person perspective from a Head/Neck surgeon who thinks his professional society should not have endorsed gun silencers. www.statnews.com/2025/09/22/e... via @statnews.com

This is a CR that (1) prevents health premiums from going way up; and (2) assures Trump actually implements the budget. So if Republicans are against it, it’s bc they will only support a spending bill that increases premiums and allows Trump’s lawlessness? Yes. True story.

MSK pediatric hematologist-oncologist Dr. Neerav Shukla, who led the research, shares that the testing provides real-time diagnostic, prognostic, and therapeutic information to local physicians and their patients. Learn more ⬇️

New research from MSK shows the Make-an-IMPACT program, a tumor test developed at MSK, improves global access to #genomic testing in #pediatric cancer patients.

“ABC and CBS are making a serious miscalculation. Their servility to Trump will not earn them peace, only greater pressure.” That’s the German professional association of journalists, @djv.de, calling on major US media to support their journalists instead of preemptively silencing them.

Super pleased to announce our latest suggesting the cell of origin for #SCLC is most likely the basal cell @nature.com, not the accepted neuroendocrine cell. Implications for the earliest events in cancer, & providing new models of tuft-like cancer. rdcu.be/eGUtj

Today, we released the results of a national survey measuring voters’ attitudes about federal funding for medical research, which found 89% of voters support using federal funds for medical research, and 83% want increased funding for cancer research. Learn more: buff.ly/bBaDDVJ

A normal Tuesday with Fox31 local news in my office…

Trump's first-term surgeon general cites misinformation, failed leadership, and lying to Congress as the reasons 'RFK has got to go' in Q&A with STAT. www.statnews.com/2025/09/15/j...

FDA's draft guidance on the assessment of overall survival in oncology trials www.fda.gov/regulatory-i...

Interesting evidence for genetics explaining disparities in T2D. Previous work identified a Neanderthal introgressed haplotype common to Native American ancestry with a large effect on T2D (pmc.ncbi.nlm.nih.gov/articles/PMC...). Wonder if there's power to look at archaic admixture here.

A PSA on PSA from @glaucomflecken.bsky.social... www.youtube.com/shorts/_u0CW...

After three years I feel ready to enter a new phase of patient empowerment by publicly disclosing my own disgnosis. This went live today and all good. news.cuanschutz.edu/cancer-cente...

Coming up at #WCLC25: @mskcancercenter.bsky.social's Helena Yu will highlight diagnostic and treatment opportunities for #leptomeningealdisease in oncogene-driven non-small cell #lungcancer. #LCSM @iaslc.bsky.social September 7 | 3:53 p.m. CEST ➡️ bit.ly/4mOHBnV

Don't miss an opportunity to learn from the Chief of the Thoracic Oncology Service at @mskcancercenter.bsky.social! At #WCLC25, Mark Awad will share lessons about work-life balance in high-stress medical careers. #LCSM @iaslc.bsky.social September 7 | 1:45 p.m. CEST ➡️ bit.ly/3HTNpxr

Tomorrow morning, #lungcancer expert Mark Kris will discuss clinicopathologic features of TP53/RB1-mutant squamous cell lung cancers at #WCLC25. #LCSM @iaslc.bsky.social @mskcancercenter.bsky.social September 8 | 10:30 a.m.. CEST ➡️ bit.ly/41EZM7b

Clearly stated by the Lancet www.thelancet.com/journals/lan...

MARIPOSA phase 3 trial: In advanced non–small-cell lung cancer with EGFR mutations, amivantamab–lazertinib led to longer overall survival than osimertinib but was associated with an increased risk of adverse events of grade 3 or higher. nej.md/4p6j53k #WCLC25 | @iaslc.bsky.social

The mass is roughly equal to a million suns. It would take over the sky if you could see it. But you can't, because it's dark matter, like 85% of the mass in the universe. "There are more things in heaven and earth, Horatio, than are dreamt of in your philosophy." www.science.org/content/arti...

Looking forward to playing with @drsanjaypopat.bsky.social - a lot of fun rehearsing covers and @mayhemtomi tracks. Check us out tonight @iaslc.bsky.social #wclc2025

Fun debate between @stephenvliu.bsky.social and Mara Antonoff on value of social medicine in oncology today. #WCLC2025

Happening tomorrow at #WCLC25: @mskcancercenter.bsky.social's @charlesrudin.bsky.social will highlight future directions in small cell #lungcancer research. Follow along for coverage of the latest advances. #LCSM #SCLC @iaslc.bsky.social September 6 | 10:30 a.m. CEST ➡️ bit.ly/3HJJmnp

Happening Monday, 9/8 at #WCLC25: MSK pathologist Dr. Natasha Rekhtman will discuss optimizing front-line treatment for small cell #lung cancer. Follow along for coverage of the latest advances. #LCSM #SCLC @iaslc.bsky.social 📆: September 8 at 5 p.m. CEST Learn more: bit.ly/4mXBiig

For those of you wondering why newer antibodies are now called -tugs -barts -migs and -ments not -mabs, this is the official @who.int INN explainer tinyurl.com/49bxfn4t

we can do amazing things, so long as our hands aren’t tied behind our back

PRO PUBLICA: “.. at least three of Trump’s Cabinet members call multiple homes their primary residences on mortgages. * Labor Secretary Lori Chavez-DeRemer .. * Transportation Secretary Sean Duffy .. * EPA administrator Lee Zeldin @propublica.org www.propublica.org/article/trum...

I guess “gold standard science” means “trade ya this pile of iron pyrite (fool’s gold) for all the gold in Fort Knox” these are charlatans and swindlers

That is a pretty accurate description of what is happening here.

New: Trump Is Accusing Foes With Multiple Mortgages of Fraud. Records Show 3 of His Cabinet Members Have Them. www.propublica.org/article/trum... w/ @robert-faturechi.bsky.social @amierjeski.bsky.social

The Posse Comitatus Act makes it illegal to use federal troops for domestic policing under normal circumstances. On Tuesday a Federal District Court in San Francisco held that the administration has been using those troops too expansively in Los Angeles.

Cancer cells are notoriously plastic, but what triggers the changes in cell state? In our new Nature (@nature.com)‬ paper, Miranda Hunter (@mrndhntr.bsky.social‬) found that mechanical pressure is a key to this switch. Check it out here: go.nature.com/47iwDm2