And here is my story: ‘Absolute hell’: Irishman with valid US work permit held by Ice since September www.irishtimes.com/world/us/202...

Amongst other things, this again highlights the core point about due process. It’s bad enough to be in a “show me your papers” situation, but your precious citizen/non-citizen, “legal”/“illegal” distinctions are meaningless when you can’t prove anything to authorities because they don’t give a shit.

Highly recommend this one if you're interested in where AI in the practice of medicine is headed. www.youtube.com/watch?v=_eDH...

Lesson one: You don't know shit and you need everyone else involved way more than they need you. 😜

This new article comes at things from a different perspective. And yes, that letter is written. www.astro.org/news-and-pub...

Robodoc, #PCP of the future with #AI may still need work in reading patients’ #Emotions. #GraphicMedicine

Did you know that OpenAI buys stock in AMD, announces it will buy a crapton of chips, then sells the stock to use the proceeds to buy said chips? Crazytown

My top 10 books for 2025

At the @theaacr.bsky.social special conference on the rise of early-onset #cancers, Dr. Luis Diaz will present in a session about opportunities for early interception. Andrea Cercek is the conference co-chair. @mskcancercenter.bsky.social #AACRearlyonset25 TODAY | 11:10 a.m. ET bit.ly/4qlOXB1

Dr. Quynh Long Khuong from UPenn presents on possible use of BB/ACEi to reduce cardiotoxicity in pediatric pts w/ AML receiving anthracycline-based induction using multicenter cohort. 908 pts studied; modest but significant reduction in LVEF reduction and mortality w/ BB. (1/2) #ASH25

Great work by super talented @mskcancercenter.bsky.social BMT Lab Faculty Jennifer Tsai @mskdeptofmed.bsky.social #ash25

In a new story, @mariojoze.bsky.social and I look at the new studies and reasons for this gap: www.statnews.com/2025/12/03/a...

Conservative columnist George Will gets it. In a piece titled "A sickening moral slum of an administration," Will writes: "Defense Secretary Pete Hegseth seems to be a war criminal. Without a war. An interesting achievement." www.washingtonpost.com/opinions/202...

Other countries don't necessarily condone overt bribery even our present administration actively encourages (even solicits) it. www.reuters.com/business/swi...

Senator Kelly is correct. Plus a Public Service Announcement: KEY section of Department of Defense's Law of War Manual is 18.3.2.1. The VERY rule on the "requirement" to refuse illegal orders gives as its paradigmatic example of what is "clearly illegal: "orders to fire upon the shipwrecked."

I am thinking that the past is prologue as they say. Whatever future I have is what I want to add value through

thepatientstory.com/patient-stor... The patient story went deep with me. Perhaps the whole voiceover and stock video (it’s obviously not me fondling their shoulder in the video, for example) isn’t the format I was expecting but Stephanie knows her audience way better than me.

“You are taking the decision away from the reviewers, and you’re putting it in the hands of the political leaders of FDA,” Fernandez Lynch said. It doesn't take an expert to understand how bad this is. More great reporting from @lizzylawrence.bsky.social www.statnews.com/2025/11/21/t...

The number of ways this is disgraceful behavior from the Secretary of Defense is...a lot. Service members do have a duty to refuse illegal orders All Americans have a 1st Amendment right to say that out loud.

Translation from Swedish to English Director Bhattacharya: As a scientist, when you see negative excess deaths starting during a serious disease outbreak, does that cause you to question the assumptions of your model?

We are looking for a new Chair of our Department of Imaging. Please RP! www.nejmcareercenter.org/job/940419/c... #imaging #radiology

Discussion of FDAs new super-rapid review process and criteria to get such rapid reviews. www.statnews.com/2025/11/21/f... via @statnews.com

Editorial in @jama.com : jamanetwork.com/journals/jam... @sequistud.bsky.social Letter with data: jamanetwork.com/journals/jam...

Trump has murdered at least 83 people with extrajudicial military strikes on alleged drug-trafficking boats. He needs to face consequences for this. His secretary of DHHS, RFK Jr., will kill several orders of magnitude more with this disinformation.

In this season of performance evaluations, let’s keep the focus and the feedback flowing to those who are there to receive it...and not bask in the glory of one’s own reflections. #leadership #worklife

The official CDC website on autism and vaccines is now a screed of cherry-picked data and conspiratorial thinking claiming that actually vaccines *might* cause autism. This is where we’re at folks… 🧪

Nice to see online from @kcarbourmd.bsky.social @jessieross.bsky.social and colleagues. Shows overlap of MTAP del and EGFR mut at baseline and resistance. Evidence of potential treatment option www.jto.org/article/S155... @mskcancercenter.bsky.social @iaslc.bsky.social @jtoonline.bsky.social

At New York Lung, Charlie Rudin @mskdeptofmed.bsky.social showing trials and investigators representing future approaches in small cell lung cancer @jessieross.bsky.social

More mechanisms of resistance to anti-HER2 ADCs, this time with a focus on loss of target interaction!

ADC resistance is likely heterogeneous, and the phenomena above may explain only a portion of cases. But these early clues can inform prospective trail efforts, as well as ADC sequencing strategies. There is much more to come!

In this manuscript, online today in Cancer Discovery, we investigate target-mediated resistance to ADCs, and propose ways to overcome it. aacrjournals.org/cancerdiscov...

Now online in Cancer Discovery @aacrjournals.bsky.social: Trastuzumab Deruxtecan (T-DXd) Resistance via Loss of HER2 Expression and Binding - by Wanyi Chen, @joshdragomd.bsky.social, @saratchandarlapaty.bsky.social, and colleagues doi.org/10.1158/2159... @mskcancercenter.bsky.social

Interesting article out this week from Dr. Bishal Gyawali, arguing that we should use more superiority designs for treatment de-escalation studies in cancer. "The burden of proof in medicine lies on more treatment." academic.oup.com/jnci/advance...

This Congress will be in session tomorrow. Join us live or online! Great speakers with a multidisciplinary agenda. web.cvent.com/event/35cf07...

I cancelled a full day of clinic 4 months ago for my study section meeting that was supposed to happen this week. Clearing our schedules to reschedule these cancelled grant review panels is not so easy…

Well reported story on the PBS News Hour about science cuts and the ongoing and potential brain drain. www.youtube.com/watch?v=yLvO... Thanks to Terrance Tao and other scientists at various career stages for having the courage to speak out. Watch and share! 1/7

Clinic Me: Ok, middle school already! Kiddo, 12: Yep. Me: You must be in 6 or 7th gra...Oh no. 12: SIX SEVEN SIX SEVEN SIX SEVEN-HahahahHA! Me: The weird thing is, I know what that is, but I still don't understand it 12: Exactly! It's not for grownups Me: Oh, well I'm fine with THAT. #Pediatrics.

I have a number of colleagues who think that LLMs will be very useful as individualized tutors. One of their arguments is that unlike previous generations of AI tutors, LLMs have the full context window of the conversation and that’s better understand what a student knows and doesn’t know.

My quote of the day Leadership is solving problems. The day soldiers stop bringing you their problems is the day you have stopped leading them. They have either lost confidence that you can help or concluded you do not care. Either case is a failure of leadership. Colin Powell

#Teen #Parent Milestone When you discover that imitation is the sincerest form of flattery….right?

In a way, every exam room is like a theater. Kids seem to know this and not know this. #pedsky

Seasonal diagnosis dept. Potential presentation of #Halloween sugar rush.

Medicaid cuts. Shutdowns... US #healthcare has its work cut out for it—to cut costs. However, as we care for our patients, we need not be pennywise and poundfoolish. #medsky #graphicmedicine

The worst thing about all the automated accounts flooding social media is that there is no point in trolling them.

Love this. Free link: www.nytimes.com/2025/10/28/a...

Excited to announce a new publication from our @mskcancercenter.bsky.social Histiocytosis group identifying a predictor for impaired response to MEK inhibition in histiocytosis patients and potential for ERK inhibition. Out today in @Cancer_Cell. www.sciencedirect.com/science/arti...

Here, Dr. Pedram Razavi explains MSK's efforts to prevent drug resistance from developing in #breastcancer patients. A new study seeks to anticipate the malignant cells' next move, like playing poker with cancer and being able to see most of its cards. Learn more: bit.ly/47cxyDZ