We just posted a new preprint describing an anti-MRSA phage targeting the terminal β-GlcNAc on wall teichoic acid. The host becomes phage resistant, but methicillin susceptibility is the consequence in some pathways; cotreatment with methicillin is synergistic at achievable MICs. #phagesky #IDsky

Our latest video in our partnership with @glaucomflecken.bsky.social summarizes a new trial investigating the mass administration of ivermectin for reducing malaria transmission. Read the full results of the BOHEMIA trial for free: nej.md/DrG31

I started studying phages just over 4 years ago. The project that started it all is finally published. We isolated 6 closely related anti-Acinetobacter phages and showed that they are not capsule-specific and can reduce bacterial load in a rat model. More work still to come on this! #phagesky #IDsky

If there was any doubt at all that the CDC is fully destroyed, this page on autism and vaccines on its website confirms it. It's now just another vessel of dangerous health misinformation. I have no words. This is beyond sad.

@puzzlebetter.bsky.social www.youtube.com/shorts/Q8UGF...

Hoping this is the start of something great - Lassa is a scourge

@isv-news.bsky.social #ISV2025 Alec Freyn, Moderna presenting ISV Paper of the Year 2025 - quadrivalent mRNA vaccine against a broad spectrum of orthopoxviruses.

Glad to see someone is still trying this drug for the US! The FDA declined to approve a few years ago based on (if I remember right) some issues about prespecified endpoints on an otherwise solid trial. I have concerns about overuse, but this could keep people out of hospital and off OPAT. #IDSky

Speaking for all physicians and healthcare providers here. When we see patients in need of care especially in an emergency room we do not leave them for dead. We do not care about their immigration status, we treat them because that is what we took an oath to do and is also basic human decency.

There are lots of things I wish I knew - today I wish I knew how to use Python (or had the time to learn!). Right after that is my wish that someone would put Bacphlip on the phage.galaxy.eu UI so old fogies like me who learned chemistry instead of programming can use it 😭 #phage

"First do not harm" is not a suggestion it is a core feature of the job. If you can't check your biases at the door when you provide healthcare, find another job. Calling ICE on a patient is some disgusting behavior. www.washingtonpost.com/health/2025/...

Raw milk in the US has significant safety issues, no matter what some folks say. #IDSky

A must read

This is a nice report - goes along with anecdotal data as well as extrapolation from dalbavancin. What is wild, though, is that 9 of 27 patients in this study had PSSA. 33%!! I think I saw a PSSA isolate once... #IDSky

RFK Jr. spouted dangerous vaccine falsehoods on national TV. As a parent and infectious diseases doctor, I couldn't stay silent. Here's what the data actually shows. 🧵

New moment of “WTF”: -pt with rare infection (so rare will leave unnamed, as could reveal identity) -nl times: reach out to CDC for testing -now: “they confirmed they are not currently accepting specimens for serology…they suggested we could reach out to Canada National Reference Center” 😳😳😳

Short but accurate - firing the ACIP experts hurts everyone. #IDSky www.idsociety.org/news--public...

The ongoing tragedy of American withdrawal from aid programs: www.npr.org/sections/goa...

Another Recovery paper. I think this one is a victim to earlier success. Study numbers are low, most had vaccine, and most had other antivirals. I don't think you can make any conclusions here. My 2¢ - future studies need to focus on soft outcomes (hospital, ED, etc) or special populations. #IDSky

All 4 of my NIH research grants are terminated. These were grants on MDR-TB treatment & strategies for supporting adolescents living w/ HIV. This is a massive waste of resources. I am heartbroken for my Harvard team, my partners in Peru, the next generation of scientists & our country. Shame.

Inhaled bacteriophage therapy shows promise in cystic fibrosis patients In a small study, CF patients treated with the therapy saw a reduction in multidrug-resistant lung bacteria and improved lung function. www.cidrap.umn.edu/a...

🧵1/ With rising STI rates across the U.S., the very programs that protect us were slashed. Cuts to CDC’s Division of STD Prevention gut a system built to stop syphilis, gonorrhea, HIV, and more. Here’s what we’re losing and why it matters to everyone. #IDSky #PublicHealthSky

Where does TrumpElon think innovation for all their favorite biotech corporations comes from? PCR only exists because somebody was looking for bacteria in hot springs at Yellowstone. I’m just a private practice ophthalmologist who barely understands p values but even I know this shit is important.

A labor of love, finally in peer review, is up as a preprint. This manuscript describes the first group of phages I isolated and characterized after starting what has become my career research focus. 2+ years of work (during ID fellowship mid-COVID!) in one very long document 😬 #phagesky #IDSky

My former co-fellow knocking it out of the park talking about AI in Peds ID! #IDSky #PedsIDSky

Rubio terminated 5800 USAID contracts – more than 90% of its foreign aid programs – in defiance of the courts. Here’s a list of just some of the lifesaving awards that were terminated. Nearly all were Congressionally mandated. They’ve saved millions of lives. 🧵

Late yesterday, we received award termination notices for three of our primary USAID agreements. Read our full statement. pedaids.org/press-releas...

Although we are not federally funded for this summer, WE WILL STILL RUN The National Summer Undergraduate Research Project (NSURP) in 2025. We remain committed to the work that needs to be done and will continue to meet people where they are. 1/4 nsurp.org

Looks like they came for the flu vaccine first. No words for any of this. #IDSky

History taking for the win - and when was the last time you changed/filled your window washer fluid? #IDSky

Apparently I'm not the only one having this problem... NCBI/NLM with outages. Pubmed working so far at least for me... Definition of insanity.

Speechless. Currently in the hospital as the Pediatric Infectious Disease Attending & access to vital info is limited. My duty to each child that I take care of is to have to most up to date information - in order to provide the best possible care. This is unacceptable www.npr.org/sections/sho...

Go to the CDC website now enter any of these words: - lgbtq - transgender - diversity - equity Most of the links w important resources which we use daily to guide care and prioritize interventions for vulnerable populations are currently broken or removed. This erasure will harm. Do not look away.

The National HIV Curriculum, a free educational website from the University of Washington funded by the Health Resources and Services, is currently “temporarily unavailable”. Another great teaching resource for practitioners down 😡 www.hiv.uw.edu

Go Bills!

I get a lot of "lessons learned" questions. My answer is "none." We didn't learn anything. In Jon Cohen's great piece on a recent CoV pandemic meeting @science.org, Maria Van Kerkhove said "everyone is acting as though this pandemic didn’t really happen." That feels more true every day.

Finally out! Phage therapy for diabetic foot ulcers www.sciencedirect.com/science/arti...

I seem to remember there was a somewhat recent paper that showed that, for febrile neutropenia with a known source, narrowing spectrum of therapy for that source is feasible. Am I making this up? @absteward.bsky.social #IDSky

Amazing thread below #IDSky

Children's hospitals have all the fun #Medsky

I think I know the answer, but has anyone done work with phage and Finegoldia magna? I can't find anything in Pubmed, which is pretty suggestive in itself. #phage #phagetherapy

UB School of Pharmacy students work in a variety of settings, including internationally. In January, I was privileged to work with students while collaborating with physicians in Ghana. They are raising money to go again and would benefit from your help! #IDSky crowdfunding.buffalo.edu/project/44965

The joys and trials of MALDI-ToF in the micro lab. It's great to know that we're treating Kocuria spp. bacteremia rather than some unidentified GPC, but the granularity of that data makes finding historical data for antimicrobial selection that much more difficult. #IDSky

My 12 year old texted this to me today when I tried to be funny. I think I'm in trouble.

Welp, ID boards are done (adult at least), here's hoping that I only have to worry about Peds next year. Also, my brains feels run over 😩

Some phage showing up in new wastewater samples is always exciting! #phage #IDsky

Welp, I'll still be on the old bluebird at least till phage and ID content is as good here or elsewhere, but it's hard to be there with the politicization. So, here I am, with some phage along for the ride. #IDsky