An intracellular meteor shower. EB3 comets tracking growing microtubule plus-ends in a cultured cell.

Our latest paper is out! It's led by my first MSc graduate, Andrew Rideout, who did a terrific job with this project. We report some fun and confusing results about mGluR6 trafficking. www.sciencedirect.com/science/arti...

As 2025 comes to a close, my university (Dalhousie U in Halifax, Canada) is recruiting faculty, including outstanding early career researchers, and Canada Research Chairs. Applications are due January 19 2026 (was just notified today!). Please repost.

Every machine in a Hospital that diagnoses your body without cutting you open is based on a principle of Physics, discovered by a Physicist who had no interest in Medicine. If you think the world doesn’t need Basic Science, or that somehow Science has failed you, think again. #sciencematters

Application review launches on December 1, 2025. We want to read *your* application outlining a vision for a research program deciphering how membrane proteins collaborate to enable cell function, their biosynthesis, and the biophysics and structure of how membrane proteins change shape.

Dear #Neuroscience researchers, I am Guest Editing an issue in @devdynamics.bsky.social on NEURAL MIGRATION. Due date: March 31, 2026. Great opportunity to showcase your findings on neural migration. #DevBio Please reskeet 🙏 anatomypubs.onlinelibrary.wiley.com/journal/1097...

Ending my #FluorescenceFriday with this beautiful avian retina image depicting the beautiful stratification in the avian eyes. This is where complexity meets art. #retina #avian #bird #plexiformlayer

We replaced the gaskets on the gel pouring rigs with foam weatherstrip a few months ago. No leaks yet!

My department at Emory is a hiring a tenure-track neuroscientist! Anyone who's talked to me in the last 4 years knows I cannot say enough good things about my dept and the neuroscience community here. My colleagues are so wonderfully supportive. Postdocs, please apply! apply.interfolio.com/174371

WE ARE... hiring! Penn State Biology & the Huck Institutes of the Life Sciences is recruiting a tenure track or tenured neurobiologist (Assistant or Associate Professor rank), and the committee is open to a broad scope of scientific questions. psu.wd1.myworkdayjobs.com/PSU_Academic...

Be our new colleague! 🎉 The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor. 👉 More details here: lnkd.in/e8Z9eAm4 👉 Our department: mocel.unige.ch Please feel free to share this opportunity with your network.

New paper! Kudos to first author Jaeeun Lee, who is a fantastic and hard working student. We showed that at photoreceptor presynapses, ELFN1 enrichment depends on postsynaptic mGluR6. www.jneurosci.org/content/earl...

The mysterious non-PSD localization of PSD95 🟣 in the retina outer plexiform layer... co-stained for postsynaptic TRPM1 🟢 #FluorescenceFriday

Dalhousie University invites applications for the position of Dean, Faculty of Medicine. This is a pivotal leadership opportunity to shape the future of medical education, research, and healthcare across the Maritime provinces in Canada. 5 yr renewable appointment dal.peopleadmin.ca/postings/19319

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages. ki.se/en/about-ki/...

New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...

I updated my funding curves last night. Here are the results for new and competitive renewal grants. The rate of investment has dropped substantially. This is apparently due to a requirement for DOGE review. I am calling this effect the "Downward DOGE" 1/2

Funding freeze at Northwestern from Emma Mairson at grant-watch.us. Data from USAspending. Normally, ~$70 M per month. Now, bupkis. Northwestern is keeping research moving and must be spending ~$40 M per month. Clearly not sustainable for too long.

Posted by @mit.edu on another platform

Wonder doesn’t flinch. It’s our compass pulling us toward curiosity, creativity It reminds us: #science & #discovery are good. Here’s a moment that stirred mine: a new PI(3,4)P₂ probe illuminating the cell membrane & endosomes. Marvel with me. Captured on #FluorescenceFriday for #MicroscopyMonday

An elegant ON bipolar cell expressing ER marker mEmerald-Sec61 🟦 and co-stained with mGluR6 antibody 🟥. #FluorescenceFriday More info in this old paper: www.eneuro.org/content/5/3/...

Have you ever seen the black box that is the inside of a microscope objective? Today Dr. Stephen Ross of Nikon gave a fascinating lecture on what goes into the design and manufacturing of an objective.

Lab lunch 😀

www.nature.com/naturecareer... UBC LSI Job!!

FACULTY JOB ALERT! The Albert Einstein Dept of Neuroscience is hiring a new assistant professor in any area of neuroscience! We have funds specifically earmarked for this search. #Neuroscience #AcademicJobs #NeuroSky Job just posted: faculty-einstein.icims.com/jobs/17175/f... Please share widely!!

as I tell my Genetics class every year, this breakthrough is based on 70 years of NIH-funded, basic research, commercialized by biotech bsky.app/profile/need...

🧪🚨 NSF's Directorate for STEM Education (EDU) has halted making nearly all new awards since inauguration day. Among *many* other things, EDU runs the Graduate Research Fellowship Program (GRFP). We need to protect the education & training of the next gen of scientists #StandUpForScience Thread👇🧵

An excellent opportunity! And I'm not just saying that because I'll be teaching an imaging and comparative retinal anatomy workshop during this course 😁 👀 Financial aid is available!

Submitted a new CIHR grant today. I don't suppose it will be funded, but I'm grateful to at least have a functional federal agency to submit it to. Also - sunset in the retina lab kitchen:

Extending my grant update this morning. Here are data limited to new and competitive renewal applications. The Pause is dead, Long live the Pause...

Some good-ish news from NIH “Federal Register notices for study sections run by CSR (but not those by ICs) will start being permitted again” As far as I know, the timing for this is not clear, but I will be checking the Federal Register.

Guardian article on NIH www.theguardian.com/us-news/2025...

Study sections scheduled for this past week that were canceled:

We all owe @jeremymberg.bsky.social a debt of gratitude for his work in clarifying, connecting, and advocating for science in this chaotic time. 🙏🏼

NEW: NSF confirmed that they fired 168 employees today, out of their staff of ~1,500 feds. This includes some people who'd finished their 1-year probationary periods, which were extended to 2-years last month without explanation. More to come.

President Donald Trump’s administration today moved to fire 5200 workers at the Department of Health and Human Services, using supervisors across the vast agency to warn probationary employees that they would soon receive termination notices. scim.ag/4jYmcYA

The damage today (actually yesterday) to the intramural program appears to especially bad. It also appears (although I need more confirmation) that most or all of the tenure track investigators in their first 2 years in several, and perhaps all, institutes were terminated. 7/n

I have an open position for a postdoc to study neurodevelopmental disorders in the retina using two-photon imaging and electrophysiology!

New job ad posted: Tenure track position in comparative physiology – Assistant Professor at the University of Ottawa https://buff.ly/40RUCn4 #neurojobs

BREAKING On Monday, Popular Information broke the news that the NIH had frozen virtually all grant funding in violation of 2 federal court orders On Wednesday, NIH leadership distributed a memo, acknowledging that its funding freeze was illegal and directing staff to resume issuing grants.

A coalition of attorneys general from 22 states announced Monday they are suing the Trump administration to stop steep cuts to how medical research grants are funded by the National Institutes of Health. www.mass.gov/news/ag-camp...

Some numbers here.

If this stands science will be destroyed in our country.

Wow. They went for the 3rd rail. This will get the universities off the sidelines.

The new NIH policy for indirect costs going forward is capped at 15%. This is forever going to alter the science ecosystem, upending and destroying a number of programs at universities across the country. grants.nih.gov/grants/guide...

My students give me hope for the future!

The NSF is the US engine of basic science discovery and technology innovation. This decision is a gift to our overseas competitors.

BREAKING NEWS: CDC orders mass retraction and revision of submitted research across all science and medicine journals. Banned terms must be scrubbed. Goes beyond MMWR +other CDC pubs. Applies to research already submitted to top medical journals. Take a look. open.substack.com/pub/insideme...