Engineered β cells with a mutant CD155 help evade immune attack, offering a promising therapeutic approach for type 1 diabetes @bruskolab.bsky.social www.science.org/doi/10.1126/...

@biorxivpreprint.bsky.social High-affinity CD155 expression enhances immune evasion of Stem cell-derived β-cells, improving their potential for restorative therapy in type 1 diabetes @bruskolab.bsky.social ‪@mebrown4.bsky.social‬ www.biorxiv.org/content/10.1...

Early identification of pre-clinical type 1 #diabetes combining autoantibody screening and metabolic monitoring at a single centre fully prevented #DKA at disease onset in relatives of affected patients. #T1D #DiabetesResearch link.springer.com/article/10.1... 🔓

Our latest preprint on cellular and molecular phenotypes in T1D is out now. www.biorxiv.org/content/10.1...

🚨New work from our lab with important clinical implications. Thanks to our collaborators in @TheHPAP. Spatial transcriptomics from pancreas and local draining lymph node tissue reveals a lymphotoxin-β signature in human type 1 diabetes | bioRxiv www.biorxiv.org/content/10.1...

Happening today!

This paper from cancer should be read by all as a challenge to conventional dogmas. journals.plos.org/plosbiology/...

Science, folks. Science. This is wonderful news.

🎉FOCIS is celebrating 25 years of innovation and impact! 🎉 This June, we’re marking a milestone in our journey of embracing diverse perspectives and fostering global collaboration. 🌍✨ Learn more about what’s coming 👉 zurl.co/iFu1c #FOCIS2025 #Celebrating25Years

If I did not worry about future prospects for my trainees, I don’t think I would ever publish beyond pre-prints unless there were free open-access society journals.

Extremely pleased to share our new work in collaboration with the @bruskolab.bsky.social lab, where we leveraged one of the largest TCRbeta sequencing datasets to identify T1D-associated TCR-based signatures. Paper link and 🧵 are below. Incredible work led by @puneet021192.bsky.social.

Therapeutic targeting of the T1D-associated costimulatory molecule CD226. rdcu.be/d2A3k

I clearly feel more comfortable on the water than in the Arizona desert but it was a fun Thanksgiving in both places.

I was honored to talk to @evartesfaye.bsky.social about one community’s effort to stay put in the face of climate change. “The oyster reef is a living thing. … When the sea level rises, because oysters are growing on it, it will grow vertically as well, so it will continue to add protection.” — me

Please join us for this amazing event. Looking forward to seeing these talks. @ufdiabetes @breakthrought1d.bsky.social

Cedar Key

Looking forward to seeing more science, less garbage.