Fantastic time at #HUPO2025 in Toronto! Congratulations to our talented Early Career researchers! Proud winners: Oeller Marc Oeller🥇 1st Place Poster, Kathrin Korff 🥈 Runner-up Poster, and @carolineweiss.bsky.social 🎤 3-Minute Thesis award! The future of #proteomics research is bright!

Scaling plasma proteomics to 6400 patients? Hear Lili Niu at our #HUPO2025 breakfast on how 1152 samples/day and a 200 SPD Evosep Eno + Orbitrap Astral workflow quantified >400 proteins per sample. Register: www.evosep.com/hupo2025/

This #hupo2025 marks the first HUPO since I became a group leader last month at Shenzhen Bay Laboratory in Shenzhen, China. I will be presenting a talk and a poster👇 Looking very much forward to connecting with old friends and meeting new ones!

If you are at HUPO 2025, catch up with our team @mannlab.bsky.social to hear about our exciting work in single-cell proteomics, immunopeptidomics, spatial proteomics, and the latest advances in mass spectrometry technology!

🎉 Congratulations to Matthias Mann on 20 years leading Proteomics & Signal Transduction at MPI of Biochemistry! Two decades of groundbreaking mass spectrometry research and training excellent future scientists. #MS #Proteomics #Science @mannlab.bsky.social

Very excited that our work describing hu.MAP3.0 is published in @molsystbiol.org. Here we use machine learning to integrate >25k mass spectrometry experiments to place ~70% of human proteins into 15k protein complexes. www.embopress.org/doi/full/10....

New from @mannlab.bsky.social Champions of Europe! 1200+ proteins from plasma. More of this please. bsky.app/profile/mann...

Neat plasma from yielding 1200+ proteins from a >3000 samples study is phenomenal.. Even more phenomenal is demonstrating the feasibility of linear comparisons across samples acquired over 2.5 months of instrument time.. Awesome..

Out today in Nature Genetics: Using MS-based proteomics, we mapped 1,200+ plasma proteins in 2,100+ children, showing how genetics & development shape blood protein levels during childhood. nature.com/articles/s41588-025-02089-2 #PediatricProteomics #pQTL First author @liliniu.bsky.social explains ⬇️

A perturbation proteomics-based foundation model for virtual cell construction https://www.biorxiv.org/content/10.1101/2025.02.07.637070v1

Not every analysis of multiple (<whatever>) requires multiplicity adjustments (correcting p-values for multiple testing): www.sciencedirect.com/science/arti...

A Chinese-built large language model called DeepSeek-R1 is thrilling scientists as an affordable and open rival to ‘reasoning’ models such as OpenAI’s o1 https://go.nature.com/3WroTb1

Nice review of plasma proteomics methods by Josh Coon and his group . However the perchloric acid treatment of plasma will lead to the formation of cysteic acid and methionine sulphone which is not mentioned for the DIA search. .https://www.biorxiv.org/content/10.1101/2025.01.08.632035v1