Never been a fan of the so-called number game.. However, it is indeed exciting when you get to see 100 precursors identified per second from biological samples, not just from a std digest.. Pretty stoked by having a front raw seat to witness the technology evolution through ages..😊😊 #MassSpecMusings

The EMBL #ARISE2 Fellowship Programme, funded by MSCA, opens for applications 30 June. This unique opportunity trains researchers to lead #ResearchInfrastructures & innovate in #LifeSciences. 🧪 🗓️ Join our webinar on Thursday, 2 July at 09:30 CET: embl-org.zoom.us/webinar/regi... #careers

#TeamMassSpec, may I please check if there is a lab where Thermo #Ardia is seamlessly connected to multiple mass specs and process proteomics data processing and management on the server itself?? If yes, can I please have a brief chat?? I am interested in hearing more about it.. Thanks very much..

What is the magic soup in the PreOmics iST kit, I wonder.. It is getting me 6000 proteins from tiny FFPE samples!! Whereas the conventional workflow is hardly touching 1000 proteins!!

Another UK chemistry department in trouble - this time Sheffield. savesheffieldchemistry.netlify.app

Is there any option to remove the contaminant proteins prior to normalisation in #Spectronaut?? Essentially, I would like to identify them, but don't want to include their abundance values for cross run normalisation.. is there a possibility?? Thanks very much..

Hello #Spectronaut users and manufacturers.. Is there any option to export both the raw and normalized PG.Quantity values?? Is it not possible at all or am I missing something here?? Thanks very much..

A nature-inspired ion trap for parallel manipulation of ions on a massive scale www.science.org/doi/... --- #proteomics #prot-paper

Wow! www.nature.com/articles/s41... Here we report all five canonical nucleobases—purines (adenine and guanine) and pyrimidines (cytosine, thymine and uracil)—in samples returned from the C-type asteroid (162173) Ryugu

Setting up a decent DDA method on Astral is so mentally taxing.. It isn't meant to follow any of the data dependency criteria.. Enforcing it to follow the criteria is where it gets taxing.. Wonder how it is working for those MS2-TMT workflows.. 🤔🤔

It is an incredible honour to be featured in the Faces of Mass Spectrometry series of JASMS and share the story of a nerdy mass spectrometrist.. who despite being an introvert, always love to talk about how wonderful mass spectrometry is.. ☺️☺️ Proud to be a part of #TeamMassSpec and #FeMS.. Thanks..

Today at 13:50, on the dot, the sequences running on both Ascend and Eclipse came to an abrupt stop.. Just at random.. In the middle of a run.. Neo kept running but no MS acquisition.. Had to restart Xcalibur and reconnect LC to resume the sequence.. Very spooky!!! #MassSpecMusings

Anybody doing proteomics on FACS sorted cells? People are using BSA coated tubes to avoid cell adhesion onto the walls. BSA is all over the protein extract. How to avoid this BSA? Saw Polyvinyl alcohol (PVA) can be used in place of BSA. Any experience with its compatibility for downstream MS? Thanks

"This work provides insight to help future proteomics study designers make more informed decisions on whether physical normalization is necessary for their experiments" Guess I am that old rigid mass spectrometrist now who finds it hard to keep an open mind to new concepts.. 😉😉

I have all these glycan specific fragments from a glycopeptide analysis.. Any software suggestions for identifying both the peptide and the attached glycan composition from such spectra?? Thanks very much.. #glycotime #TeamMassSpec

#TeamMassSpec Question for XL-MS practitioners.. Looking for a suitable crosslinker to stabilise a protein complex in vitro.. What are the pros and cons for MS-cleavable vs non-cleavable cross-linkers?? Is PhoX a good choice?? Any recommendations for MS-cleavable cross-linkers?? Thanks very much..

The Spatial Omics Summer School offers a structured, hands-on introduction to spatially resolved targeted transcriptomics, proteomics, and metabolomics. If you want to join, submit your application by 2 February 2026. https://www.vibconferences.be/events/spatial-omics-summer-school

(J Proteom) Two-dimensional electrophoresis-based proteomics reveals soybean seed hypocotyl proteoforms: Publication date: Available online 17 January 2026 Source: Journal of Proteomics Author(s): Jian-Zhong Tan, Hiroyuki Kagawa, Keiko Kizawa, Hisashi Hirano #MassSpecRSS

Big evaluation of our Orbitrap Astral Zoom mass spectrometer by the Olsen group, now peer reviewed, published and open access. www.sciencedirect.com/science/arti...

(JASMS) [ASAP] Faces of Mass Spectrometry/Khatereh Motamedchaboki: Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00430 (RSS) #MassSpecRSS #JASMS

Vanquish Duo as Neo Mono with EasySpray column setup.. Works quite alright.. Guess have to get uPAC to test the dual column setup at nano flow rate..

A slide from a presentation I gave in 2013 on mass spectrometry proteomics.. Ironically, still a relevant topic to include this slide as such in a talk I am preparing to give after the new year..

Holidays started.. And the festive decor is on.. 🎉🎉#MassSpecHolidayDecor

Post-doc positions: "Academic freedom is under pressure today. This requires rescue havens of free research. ... [we] invite early career researchers, whose work is restricted due to political pressure in the USA..." uni-freiburg.de/frias/call-f...

Guess at which point I realized that the column heater is not connected.. I am very glad that this is the only boss-back-on-bench catastrophe so far.. The muscle memory from years of proteomics works still.. Thankfully, nothing got blown up.. yet.. 😂😂

Damn.. Neo firmware update 2.51 locks you out of the autosampler and prevents you from opening the door once the sequence is started.. Damn..

#TeamMassSpec Can someone please help me remember whether the Vanquish Duo launched at ASMS2024 was meant for nanoLC applications?? Somehow, I remember it as the potential high speed solution from Thermo for Astral high SPD applications.. However, the Duo I got hold of here is a microflow version!!

TMT-MS2 Quan with 0.6Th ultra narrow window DIA.. 🤯

Proteomics Specialist - DTU Biosustain | JobTeaser www.jobteaser.com/fr... --- #proteomics #prot-jobs

We are thrilled to announce our 2026 election results. Olga Vitek has been elected to serve as US HUPO's President-Elect, Devin Schweppe as Secretary, and Sasha Singh and Hanno Steen were elected to serve as Members-At-Large on our Board of Directors. Congratulations to all! 🌟 #USHUPO

#Glyco people?? Just like PNGase F, is there a glycosidase that can cleave off O-glycan from S/T and leave a mass signature when the reaction is carried out in heavy water?? Thanks very much..

Even when the 96% of study sample contributors were females, the 4% males are the ones who get the mention!!! Wonder why can't the demography of the sample population be mentioned as 96% female or for better clarity as 96:4 female:male in the abstract.. Another instance of scientific gender bias??

Quick heads up - there will soon be a job posting for a Staff Scientist / Senior Staff Scientist in our lab in Copenhagen to support all our mass spec proteomics adventures! Great colleagues, lots of cool projects… and you’ll get to work with me 😅 Please DM if you’re interested!

Registration for the Round 6 of Mentorship Pods is now OPEN! More info👉 femalesinms.com/mentorship-p... Registration 👉 femalesinms.com/mentorship-p...

Changes to UniProt proteomes www.ebi.ac.uk/about/... --- #proteomics #prot-other

Hello #Proteomics folks from core labs, Have you all moved over to IonOptiks columns?? Am I the only one left?? I know these columns give awesome chromatograms. How is the longevity of these columns in core labs??? May I ask what's your best and worst column life stats?? Thanks very much..

📢 FeMS Q4 2025 Empowerment Award applications are now open! More info here 👉https://femalesinms.com/empowerment/ Apply here👉https://airtable.com/applvoZXoHURMcSCq/shrQlJoZ6f2P5yWqc #FeMS #TeamMassSpec #WomenEmpowerment

🌟 We are excited to announce that applications are now open for the Rising Star in Computational Mass Spectrometry Award! 🌟 Go to: lnkd.in/gzDuppnb to see the details and to apply! Thanks to our sponsors @chanzuckerberg.bsky.social and Open MS!

Hey @asms.org peeps. I’m running for VP for programs and I’d like your vote. Check out the asms web site for details and you will see an email with voting instructions in the near future. I approach this position with lots of experience organizing scientific conferences & I ❤️ asms. Please re-sky.

Need to do some cutting edge Proteomics Differential expression? Maybe give Limpa a try! Guaranteed to rise to the occasion ...despite its name ! youtu.be/vqeOT8xcycc

We are delighted to inform you that BSPR 2026 will be held at the @ebi.embl.org campus in Cambridge from the 13th to the 15th of July. Make sure to save the data and join us for the a meeting full of great science focused on British & Irish Proteomics. #proteomics #BSPR2026 #massspectrometry

Would you do tissue proteomics with an old sample fixed in formalin, not embedded in paraffin, and stored for quite a while immersed in formalin?? Can the proteins be extracted after subjecting to decrosslinking?? Are there any insights to share from the #paleoproteomics practitioners?? Thanks..

The biggest plus point of getting back to academia is getting to access journal articles easily.. 😊😊

ECR with <3yrs postdoc experience? The University of Manchester @officialuom.bsky.social is offering THREE Bicentenary Fellowships. 3yrs salary + £30k pa funding If you have a project involving mass spec, biomarkers and human disease, get in touch! www.bmh.manchester.ac.uk/research/sup...

The @crick.ac.uk is recruiting Early Career Group Leaders - Lab set-up, research costs, salaries for up to 5 researchers - Support for up to 12 years - Access to our core facilities - Competitive salary - Fantastic colleagues - All areas of biology Deadline 27 Nov www.crick.ac.uk/careers-stud...

There is a position open in our lab, within this network. Our project deals with assessing identification and quantification errors for MS-based proteomics. www.protaiomics.eu/project/dc13... Please check out all the project descriptions at the site below:

An international relocation doesn't mean packing up your entire life in a few bags to carry along with you anymore once you set up a base camp for yourself.. 😉😉

Postdoc Research Associate vacancy at Imperial College, @ukdri.ac.uk with Dr Samuel Barnes, using multiplexed synaptic proteomics and imaging to study early Alzheimer. Closing date: 1st October www.dementiaresearcher.nihr.ac.uk/job/research...

With IonOpticks' rapid growth come exciting opportunities to join our expanding global team. We’re looking for passionate people who want to push the boundaries of LC-MS-based research. Ready to be part of an impact-driven company making a real difference in life sciences? Visit bit.ly/4nByJSI

Join us for the guest lecture of Prof. Olga Vitek olgavitek.bsky.social, leading computational mass spec expert, for cutting-edge Stats & AI insights on Sep 24, 10am, in person or zoom. Registration: ucdavis.zoom.us/meeting/regi... #Metabolomics #AI #Massspectrometry @mikelangelipid.bsky.social