Great to be at #BSPR2026 in Hinxton this week, supporting the UK's key proteomics gathering. On Monday, conference conversations continued at our Peaks & Pints event - it's been a pleasure connecting with so many of you. If you're still here today, stop by - we'd love to hear what you're working on.

We're excited to welcome Dr Anuar Makhmut to IonOpticks as a Field Application Specialist, supporting researchers across Europe. He'll be working directly with research teams to design, optimise, and implement proteomics workflows suited to their goals. It’s fantastic to have him on board.

As a mass spec lab manager at @hhmi-science.bsky.social Howard Hughes Medical Institute, Dr Juan Liu's focus is on pushing proteome coverage deeper. After switching to the Aurora® Ultimate™ 25x150 XT for both general proteomics and phosphoproteomics workflows, the results speak for themselves:

De novo antibody sequencing typically demands 4–6 parallel protease digestions to adequately cover hypervariable CDR regions. Pañeda et al. challenge that paradigm entirely. LC-MS/MS used an Aurora® Elite™ 15×75 XS column, an UltiMate 3000, and a SCIEX ZenoTOF 7600. Learn more: bit.ly/4eshTEd

Janssens et al. benchmark the timsUltra AIP for SCP: using an Aurora® Elite™ 15×75 CSI column + nanoElute 2, the team achieved a >2× increase in protein IDs at the single-cell level, with ~50% of the detected proteome identified exclusively on the new instrument. Learn more: bit.ly/4gF6Tog

The 9th Annual Single-Cell Proteomics Conference kicks off at @northeasternu.bsky.social in Boston next week and we’re proud to be supporting as a Gold Sponsor. Jarrod, Zac, and Haley are all behind the booth. Stop by to see how we can support your workflows - or to say hi! We’d love to connect.

Few spots left for Peaks & Pints, Hinxton edition. If you'll be at BSPR, stick around on Monday, July 13 for an evening of conversation and connection at The Red Lion Inn, just a 6-minute walk from Hinxton Hall Conference Centre. Secure your complimentary, catered spot: bit.ly/4opQJRz

When your research involves thousands of glycoproteoforms, you need columns you can count on. To Dr. Tim Veth, postdoctoral researcher at the University of Washington, one Aurora column lasting several months of high performance was all the evidence he needed. Learn more: bit.ly/4nrMzad

Day 1 of the SEMM Workshop "The Proteomics Revolution: Advancing Science and Society" is wrapped up, and it's been a brilliant start to what promises to be a memorable few days in Milan. If you're here, come find us - Britta and Darren would love to connect.

Zhemkov et al. applied an exploratory, global protein identification approach across a 60-day iPSC-to-motor neuron differentiation protocol, using Aurora® Rapid™ 5x75 CSI columns on a timsTOF Ultra 2 to achieve ~20% greater sensitivity and ~175% more low-abundance protein detections. bit.ly/4aJKPFi

We're thrilled to welcome Dr Yana Demyanenko to the IonOpticks team as an Application Scientist, based in the UK. She'll help researchers get the most out of their LC-MS proteomics workflows. Outside the lab, Yana is an avid DIYer, making things from cakes to dresses to garden landscapes.

What happens to a neuron as it develops an Alzheimer's tangle? Single-cell proteomics has answers in the June 2026 Publication Digest | Plus glycogen ubiquitination, stress granule proteomics in single cells, and plasma workflow benchmarking with Aurora Series® columns Learn more: bit.ly/4oMipQV

Most virtual cell models tell you what a cell is instructed to do, not what it really does. That's the gap Dr Zilu Ye is working to close. In our spotlight, Zilu talks single-cell proteomics, the result nobody believed, & why the biggest breakthroughs may arrive sooner than expected. bit.ly/4b8dOCS

Foiani et al. from the @ukdri.ac.uk shed light on Alzheimer's disease brain tissue using single-neuron proteomics, pairing an Aurora® Elite™ 15×75 CSI column with an Evosep One and timsTOF Ultra 2. Learn more: bit.ly/4xvASoJ

A recent @sciex.bsky.social technical note benchmarks the ZenoTOF 8600 system for short-gradient, high-throughput label-free quantitative (LFQ) proteomics. Chromatography performed on an ACQUITY UPLC M-Class paired with an Aurora® Ultimate™ 25x75 XS column for nanoflow analyses. bit.ly/4vZajqn

Dr @mari-mardamshin.bsky.social, postdoctoral fellow in Assoc Prof Emma Lundberg's lab at Stanford, works at the frontier of spatial proteomics, where column robustness is crucial - especially with low-input samples. Aurora Series® columns help make that work possible. Learn more: bit.ly/3IELayn

A new @sciex.bsky.social technical note demonstrates significant improvements in label-free quantitation (LFQ) proteomics using ZT Scan DIA 3.0 on the ZenoTOF 8600 system, which was paired with an ACQUITY UPLC M-Class System and an Aurora® Ultimate™ 25x75 XS column. Learn more: bit.ly/4oAy45V

On the final afternoon of the 74th MSSJ Annual Conference on Mass Spectrometry in Yokohama, our Sweets Seminar wrapped up with 80 attendees - a wonderful turnout, and a great energy to end the conference on. Even if it was testing the limits of Fabrice’s conversational Japanese!

Davison et al. coupled nanocapillary sampling with LC-MS for the first time to profile stress granule proteins from individual live cells, bypassing the limitations of bulk purification. Used Vanquish Neo, Aurora® Rapid™ 8×75 XT column, & Orbitrap Astral. Learn more: bit.ly/3PYy6HQ

We’re proud to support the @ukbspr.bsky.social BSPR Annual Scientific Meeting in Hinxton next month. Attending? We'd love to see you at Peaks + Pints on Monday, July 13 at The Red Lion Inn from 07:30pm, a short walk from the conference venue: bit.ly/4ose7xT

Last week, our UK team had the pleasure of hosting Fintiede Solutions Solutions, IonOpticks' local distribution partner, in person at our new facility. Of course, no meeting is complete without a proper spread, including the cultural exchange that is sharing a jar of Vegemite. Or is it Marmite?

Luke Gamon, Asst Prof at @ucph.bsky.social, built a spatial proteomics workflow from standard lab equipment: PCR tubes, centrifuges, basic plastics. When a single Aurora column can handle 2,500 injections and still perform, that kind of longevity changes what's feasible. Learn more: bit.ly/4ulX2XL

Rebeca Kawahara was waiting on a competitive fellowship outcome, settled in Australia with two young children. An unexpected offer arrived: to establish a Glycoproteomics Lab in Japan. She took it. 'Sometimes the biggest growth comes from stepping into the unknown.' Read her story: bit.ly/4oiKhM4

Under the warm glow of the San Diego skyline, we welcomed over 230 of you to Deck655 for IonOpticks' annual #ASMS2026 User Event to close out a massive week of science and innovation. We look forward to inviting you to our next one at #HUPO2026 in Singapore. Photos from the night: bit.ly/4afec23

NoPro-clipping: a new @komanderlab.bsky.social nanoflow LC-MS/MS workflow from @marcojochem.bsky.social et al. using an Aurora® Elite™ 15×75 column + Orbitrap Eclipse, Vanquish Neo detects ubiquitination of glycogen, glycerol & spermine in cells & tissues via targeted PRM. Learn more: bit.ly/3PYs222

Next week, Fabrice heads to Yokohama for the 74th MSSJ Annual Conference on Mass Spectrometry, co-exhibiting with our Japanese distribution partner AMR at Stand 17. We're also hosting a Sweets Seminar on Friday 12 June at 02:00pm - a great chance to hear from an expert speaker and enjoy some treats.

Please join us in welcoming Mike Baynham to the IonOpticks team as our new Global Product Manager, joining our Global Commercial team. We look forward to the insight, expertise and customer focus Mike will bring as we continue enhancing our product portfolio for researchers around the world.

What a way to start this morning. We were pleased to see the room being full, the curiosity palpable, and the discussion lively at our #ASMS2026 breakfast seminar. If your question wasn't answered, join us at the IonOpticks booth, and hopefully you'll cross paths with the speakers on the floor too.

Grateful to everyone who stopped by Haley and Greta’s NanoShield® poster this morning at #ASMS2026 - the conversations were fantastic. Swing by booth 623 and we'd love to walk you through how NanoShield® delivers near-direct-injection performance while keeping your workflow healthy long-term.

Spots are vanishing for our #ASMS2026 breakfast seminar. It's shaping up to be a great hour before the convention floor opens. @slavov-n.bsky.social, @amandalsmythers.bsky.social, & Denys Oliinyk will join us for a conversation spanning what good separation enables. Pre-register now: bit.ly/4dvarXl

I’m hiring a Scientific Marketing Lead, LC-MS Proteomics, based in Melbourne. A rare blended role for someone who sits between science and marketing, ideal for a PhD candidate or researcher looking to move from the lab bench to industry. Details: lnkd.in/e5ZTAFew

Did you spot IonOpticks in the @sciex.bsky.social #ASMS2026 Hospitality Suite last night? We’re paired with the ZenoTOF 8600 and Evosep Eno LC for fast, precise proteomics. Stop by any night this week for a drink and to learn more about our developing SCIEX commercial partnership.

New benchmarking study compares 6 plasma proteomics workflows via DIA on an Orbitrap Astral. P2 topped the field at 4,636 protein groups vs 584 for Neat plasma. Peptide sep on an IonOpticks Aurora Series C18 column + Vanquish Neo UHPLC. Learn more: bit.ly/49amyaK #Proteomics #UHPLC

A great moment at the Thermo #ASMS2026 user meeting as Mark Larance from @sydney.edu.au highlighted the performance of Aurora® Elite™ 15x75 XT columns in his SCP workflow. Great to see this workflow pushing what's possible in high-throughput single-cell analysis.

PRESS RELEASE: IonOpticks and @sciex.bsky.social announce details of a proposed reseller and co-marketing agreement to unify Aurora Series® XS columns, HeatSync™ temperature control, and SCIEX ZenoTOF systems into performance-aligned proteomics workflows.

What a start to #ASMS2026! The welcome reception brought a lively crowd to the IonOpticks booth, with strong interest from night one. Our team loved seeing familiar faces and new connections, and we’re keen to keep the conversations going as the week progresses.

Kicking off the week of #ASMS2026, Haley and Zac joined the Bruker eXceed Symposium, a brilliant one-day deep dive into cutting-edge MS innovation ahead of the main conference. During the breaks, it was great to see our NanoShield® trap column drawing plenty of curious eyes. #MassSpectrometry

And we're off! #ASMS2026 begins tonight, and we’re excited to be back in San Diego for the biggest mass spec event of the year. Visit #teamIO at booth 623, welcome Mike Baynham, see our new NanoShield C18 trap column, grab some signature swag and register for our Wednesday breakfast seminar.

Thank you to everyone who joined Dr @brendonseale.bsky.social's IonOpticks Insights webinar on scaling core facility proteomics. You can still register to watch it on demand, along with helpful bonus materials, which you can find under "Additional Resources": bit.ly/3QRnp9T

We're delighted to welcome @amandalsmythers.bsky.social from the Gygi Lab at Harvard Medical School and Dana-Farber Cancer Institute to our #ASMS2026 breakfast seminar. She'll bring her expertise in phospho DIA on the Astral. Wednesday June 3, 7:00am Breakfast provided Register now: bit.ly/4dvarXl

This Thermo Scientific tech note tackles one of immunopeptidomics' toughest challenges: getting meaningful depth from low-level, precious clinical material. The Orbitrap Astral Zoom was paired with a Vanquish Neo and an Aurora® Ultimate™ 25×75 XT column. Read the full tech note: bit.ly/4xeEdZt

We're pleased to welcome Denys Oliinyk from the Mann Lab to our #ASMS2026 breakfast seminar. He'll join a panel discussion spanning single-cell, phospho, and DVP - and what good separation unlocks across these fields. Wednesday, 3 June, 07:00am. Breakfast provided. Register now: bit.ly/4dvarXl

Fast, sharp, and packed with insight - all before 9am. We're hosting a breakfast seminar at #ASMS2026 and we're excited to have @slavov-n.bsky.social, @amandalsmythers.bsky.social, and Denys Oliinyk as our guest speakers. Complimentary breakfast provided Register now: bit.ly/4dvarXl

Excited to have @slavov-n.bsky.social as a speaker at our #ASMS2026 Breakfast Seminar. He'll bring his single-cell perspective to a broader conversation about what good separation enables across modern proteomics workflows. Wednesday June 3, 07:00am Breakfast provided Register now: bit.ly/4dvarXl

New multi-consortium study developed a framework to classify small proteins ("microproteins"), introducing the term "peptidein" for confirmed translation products whose biological role remains unclear. LC–MS system comprised an Aurora Elite 15×75 XS column + SCIEX ZenoTOF 8600. bit.ly/3RaIYTj

Traps have long been seen as a trade-off: more robustness, less performance. But what if that compromise was never inevitable? In this opinion piece, Dr Jarrod Sandow explores how NanoShield® C18 trap columns are helping proteomics workflows become both resilient and high-performing:

At #ProteoVilamoura2026, @sciex.bsky.social's Mario Armelao delivered an impressive talk showcasing the low-input capabilities of the ZenoTOF 8600 system, when combined with the Evosep Eno paired with Aurora® Elite™ XS columns.

In highly sensitive immunopeptidomics, confidence in your column matters. Professor Tony Purcell shares how Aurora Series columns support demanding LC-MS workflows with the robustness, sensitivity, longevity and reproducibility researchers need, across Bruker timsTOF and SCIEX ZenoTOF systems.

The countdown to #ASMS2026 has well and truly begun. This year, there’s plenty to discover, from our Wednesday Breakfast Seminar to our poster presentations, seven oral presentation mentions, and more. See everything we're bringing to San Diego: bit.ly/4urDEtq

What a wonderful few days at #ProteoVilamoura2026. It was a pleasure for Britta & Joris to represent IonOpticks at this joint meeting, a tightly-knit community of proteomics researchers from Portugal, Spain, and France. It's hard to imagine a better setting for scientific exchange and reconnection.