At SCIEX's #USHUPO2026 Seminar, Dr Tim Heymann showed how the ZenoTOF 8600 + Evosep Eno + Aurora XS columns deliver robust, high-quality data across single-cell, global & targeted proteomics, without rebuilding workflows. Up to 4,700 proteins from a single cell with low CVs using 1400ms ZT Scan DIA.

Wang et al. shed light on the proteomic landscape of PMS, potential implications for biomarker discovery and future therapeutic targeting of neuroinflammatory pathways. Data acquired on Orbitrap Fusion Lumos + EASY-nLC 1200, peptides separated on Aurora Ultimate 25x75 column. go.nature.com/46lY3Gd

With day 2 about to kick off, #USHUPO2026 is in full swing. Still building your agenda? With so many excellent poster presentations, here are some that we think are worth checking out today - all in the Regency Ballroom from 4:30pm - 6:30pm. See the full list: bit.ly/3NZ3IMa

Day 1 of #USHUPO2026 is underway with strong interest in our Nanoshield™ trap columns and Aurora 150 µm analytical range for robust, high-throughput workflows. Dr. TJ Blackburn’s trap comparison poster engaged valuable discussion. Visit Booth 7 to meet our team and discuss your separations needs.

Join SCIEX’s #USHUPO2026 lunch seminar to hear Tim Heymann present how pairing the ZenoTOF 8600 with Aurora XS columns delivers high-sensitivity, stable, and reproducible proteomics workflows, powering applications from single-cell analysis to large-scale discovery studies.

Are you at #USHUPO2026? Catch Dr. TJ Blackburn's lightning talk from 3:15pm to 4:30pm (Grand DE). Can’t make it? TJ will also share this work as a poster presentation P10.03 in the Regency Ballroom from 4:30pm - 6:30pm. Learn about our full scientific presence at US HUPO: bit.ly/3NZ3IMa

"If you know your sample well, you can do meaningful spatial proteomics with just your hands and a microscope, basically." @lgamon.bsky.social is proving that breakthrough science doesn't always need expensive automation. Read about his accessible approach to heart disease research: bit.ly/3MDkjVc

Not long until #USHUPO2026 - check out Dr. TJ Blackburn’s lightning talk & poster presentation P10.03 on Mon, Feb 23 from 3:15pm. Learn the science behind NanoShield™ trap columns, how they perform in real workflows, and what that means for your robustness and consistency. Learn more: bit.ly/3NZ3IMa

Today we recognise and celebrate the women of IonOpticks on the UN's International Day of Women & Girls in Science. This year's theme reflects the importance of inclusion, opportunity & progress. Thank you for the talent, care & impact you bring to our team & the scientific community every day.

IonOpticks was proud to attend the @ubuntuproteomix.bsky.social Summer School for 2026. Dr @jsandow.bsky.social presented on chromatography fundamentals, we sponsored three students & provided our popular IO hats for all. Thanks to the organisers for another great event & we look forward to 2027.

Heard the hype about NanoShield™? Join Greta Briedytė at #LorneProteomics poster #105 to see how our new trap column improves sample cleanliness, extends analytical column life, reduces loading time, and delivers near direct-injection performance. Grab the application note at our booth.

After a great day of talks and posters at #LorneProteomics 2026, it was fantastic to host our IonOpticks Peaks and Pints event at the Lorne Hotel. Thanks to the 68 guests who joined us for a relaxed evening of conversation and catching up. Looking forward to another great day ahead.

Poster Spotlight: Emery-Corbin et al, #LorneProteomics poster #34, benchmark plasma proteomics workflows using Aurora® Ultimate™ 25×75 and Elite™ 15×75 columns. Their study shows workflow selection must be cohort-specific, revealing distinct sub-proteomes across clinical and translational settings.

Poster Spotlight: Multari et al’s #LorneProteomics poster #3 explores single-cell proteomics in Diffuse Midline Glioma (DMG). Using IonOpticks Aurora Rapid 8×75 column, it reveals radiation response heterogeneity and early resistance mechanisms, supporting discovery of future therapeutic targets.

Day one, #LorneProteomics ready. Our full delegation is on the ground and ready to connect, answer your questions, and explore how IonOpticks can help you get the most out of your LC-MS workflows. Stop by the booth during the breaks today for a chat. Better columns. Better data. Better research.

IonOpticks is at APS’s 31st Lorne Symposium (Booth 14). Discover Gen 4 Aurora Series® 75 & 150 µm columns, NanoShield™ C18 trap columns, and HeatSync™ heating. Meet our team and CCO Darren Sher, and join ‘Peaks and Pints’ at the Lorne Hotel: lnkd.in/gCEFyRiM

Shout out to our sponsors who put a little #SwagInTheBag! @evosep.bsky.social #DCYPHR @diplomics.bsky.social @ionopticks.bsky.social @resynbio.bsky.social

Register now: bit.ly/LornePeaksan... Heading to next week’s Lorne Proteomics Symposium 2026 at Mantra Lorne? With just 2 days left to register, now’s the time to lock in your spot at IonOpticks’ 'Peaks and Pints' user event on Friday 6 February, 6-10pm.

IonOpticks is pleased to announce the appointment of Darren Sher as Chief Commercial Officer: a strategic executive role providing coordinated leadership across global sales, marketing, customer support + customer processes as the company continues to scale internationally. Read the full release.

IonOpticks is proud to sponsor the 2026 @ubuntuproteomix.bsky.social in George, South Africa. Join IonOpticks' CPO @jsandow.bsky.social, on site all week and catch his sponsor presentation “Chromatography Fundamentals for Proteomic Analysis” Thursday 5 Feb, 10:30am - 12:30pm.

IonOpticks Aurora® Elite™ 15x75 XS columns with the @sciex.bsky.social ZenoTOF 8600 deliver standout low-input proteomics. SCIEX's latest app note shows ZT Scan DIA 2.0 identifying 4,000+ proteins from just 62.5 pg, with up to 94% more quantifiable proteins and CVs below 20%. Read online:

With Lorne Proteomics just a week away, join the IonOpticks team next Friday (6–9pm) at the Lorne Hotel for Peaks & Pints: an informal meetup where proteomics meets pints. Cold drinks, sharp peaks, great company. Registration essential: bit.ly/LornePeaksan...

QuantSelect: Mann lab's new deep learning framework improves DIA proteomics quantification by 12-15%. Validated on Orbitrap Astral + Evosep One with Aurora Rapid 5x75 columns. Up to 4× better sensitivity in differential expression analysis. Learn more: bit.ly/3NyqqKG @mpibiochem.bsky.social

We’re proud to support the Queensland Mass Spectrometry Symposium 2026, which kicks off next week at the Global Change Institute. Fabrice, our Distribution Channel Manager - APACI, will attend on both days, January 28-29. If you’ll be there, see if you can spot Fabrice - he'd love to connect

With February fast approaching, we’re looking forward to being part of the Fourth Ubuntu Proteomics Summer School in George, South Africa. Join Dr. @jsandow.bsky.social Jarrod Sandow to learn all about chromatography and its crucial applications in proteomics.

Dr. Xiang Zheng, Asst. Prof. at Aarhus University, extracts 1,000s of proteins from individual cell types to map cancer's complex ecosystem. Working with precious clinical samples where material is limited, he shared how column reliability enables his spatial proteomics breakthroughs. bit.ly/42jl7Ux

Three weeks left until the 31st Annual Lorne Proteomics Symposium 2026 at Mantra Lorne in Victoria. We’re at booth 14 so swing by and chat to us about how our product pipeline can elevate your research, including a closer look at our new NanoShield™ reversed-flush C18 trap columns. See you in Lorne.

New globally representative vaccine screening method from the Foster lab uses 30 diverse cell lines + LC-MS/MS to identify broadly protective antigens. Analysis via EASY-nLC 1000 + timsTOF Pro with Aurora Ultimate 25x75 CSI column, identified 18 common binding motifs. bit.ly/4qQruIe

During his graduate studies, Mahlon Collins worked with ALS patients who underwent painful spinal taps to donate CSF for his biomarker research. Now, he leads neurodegenerative disease research at @parallelsq.bsky.social. Learn more about Mahlon's journey: bit.ly/3NoKX4g

Hwang et al. develop HLA-Shuttle, a system using engineered components of the HLA-I processing machinery to restore and stabilise HLA-I complexes on tumour cell surfaces. Immunopeptidomic samples separated on Aurora Ultimate 25x75, data acquired on nanoElute 2 + timsTOF Ultra 2. bit.ly/49tdq0m

IonOpticks columns were cited over 1,000 times in 2025. That’s over 1,000 different ways in which our columns powered breakthrough research. Less than eight years ago, we were celebrating our first 10. Thank you to everyone who supported us on this journey. Explore all publications: bit.ly/4spHNgF

New year. New budget. New possibilities. Elevate your proteomics workflows in 2026 - whether that means complete LC-MS setup, stocked replacement columns, or adding trap column protection to extend analytical column life. Start the year equipped: bit.ly/4preV4S

Chemla et al. reveal how melanoma evades the immune system through an unexpected mechanism: melanosomes acting as molecular decoys. LC-MS/MS used an Aurora Ultimate 25x75 CSI column with a timsTOF Ultra and nanoElute 2. Learn more: bit.ly/4qcP426

2025 was a remarkable year. Two themes that define it for IO are recognition and reach. Awards and industry recognition validated what our community knew for years, while our team expanded across continents, bringing us closer to the researchers and partners we serve. 2025 in review: bit.ly/3MQpEIG

Wrapping up an unforgettable PSI-2025. It’s not every day we're at a conference where we can barely sit - the interest in our leading chromatography solutions was truly non-stop. And where else do you get to exhibit outdoors in beautiful Hyderabad? Thank you to the organisers for a great event.

A big year for us at IonOpticks! It's always nice to look back on a recap like this to see all we've achieved. Hats off to #teamIO who never fail to impress. Your dedication and unrelenting commitment have resulted in a mammoth year of monumental steps forward!

What a year it’s been - time to recharge and enjoy a well-earned break. Our office will be closed from December 25th to January 4th and we’ll be back online from Monday, January 5th. We wish you a safe and festive holiday break. See you in 2026!

The ZenoTOF 8600 paired with Aurora Series columns: a powerful combination showcased by @sciex.bsky.social’s Jean-Baptiste Vincendet at PSI-2025. >10,000 protein group IDs from 250 ng K562 cell line. Eager to see what else researchers achieve as adoption of the ZenoTOF 8600 system continues to grow.

12-lab study shows that DIA methods ID 1.8× more proteins than traditional DDA approaches in plasma analysis, with significantly better reproducibility (5.9% vs 15.4% CV). Distler et al.'s standardised approach brings clinical proteomics closer to accredited diagnostics. bit.ly/492ZhXk

TWO WEEKS LEFT: Say yes to every sample with a complimentary 3-pack of NEW NanoShield™ reversed-flush C18 trap columns with every HeatSync™ Starter Pack, and Aurora Series® 5 and 10-pack through December! Shop online or request a quote: bit.ly/4pPMP44 Promotion ends 11:59pm AEDT December 31, 2025

Zhang et al. develop SPIDR (Single-cell Protein Immobilisation and Digestion tube Reactor), an accessible, high-throughput approach that simplifies single-cell proteomics for resource-limited labs. LC-MS/MS used Aurora Ultimate 25x75 CSI column on nanoElute coupled to timsTOF Pro 2. bit.ly/44iDR7e

Please welcome Haley Oller as Field Application Specialist - North America. With over a decade of experience in MS and proteomics, Haley brings technical expertise and a passion for collaborative science. She's excited to support proteomic scientists and help facilitate the next wave of discoveries.

Anyone who’s been to our User Appreciation Events knows how important events are to us, which is why we're thrilled to welcome Annie Ward as our Global Events Manager. Our User Event in Toronto was all Annie - we can’t wait to see how she shapes our upcoming events into unforgettable experiences.

NOW PUBLISHED: An open-source framework, alphaDIA, uses a feature-free approach to process complex spectral data, outperforming existing methods across various platforms. Samples separated on Aurora Elite 15x75 by Whisper 40SPD method & on Aurora Rapid 8x150 by Whisper 60SPD. bit.ly/48Go0R9

Callahan et al. suggest the kinase Itk as a potential target for reducing unwanted CAR activity. Phosphotyrosine-enriched peptides separated with Vanquish Neo & Aurora Ultimate 25x75 column. MS performed on an Orbitrap Ascend. bit.ly/3Mn9Ugc

Get a complimentary 3-pack of NEW NanoShield™ trap columns with every Aurora Series starter pack, 5-pack, or 10-pack. Run every sample confidently, knowing your analytical columns are safeguarded. Start 2026 fully stocked AND protected. Stock up before December 31, 11:59pm AEST: bit.ly/4pPMP44

It’s been a great start to ITPA 2025 - talking to local customers, getting to know the Italian proteomics community, and the challenges they're facing. Stop by our exhibition booth and chat to Britta to learn more, share your challenges, and explore NanoShield™ with a dedicated new application note.

Recognition is most impactful when it’s consistent and done in a variety of ways. On Friday, we added a whole new way of recognising our people, incorporating IonOpticks' Employee Values Awards into our EOY staff event. Thank you to everyone in the team for making every day at IonOpticks a pleasure.

We kicked off our first user networking event in Montréal, bringing together new and familiar faces from the mass spec community over curated Canadian craft beers. A great turnout, great conversations, and plenty of collaborative energy. We can’t wait to host more events globally.

Yesterday, IonOpticks and SCIEX hosted a hands-on Proteomics in Practice workshop at SCIEX’s Toronto R&D site, giving attendees real-world experience with IonOpticks columns and ZenoTOF systems. Thanks to Tim Heymann, Shelley Jager, Reza Dorvash, Patrick Pribil, Katherine Tran and Jarrod Sandow.