Michael Sinden
@mdsinden.bsky.social
📤 304
📥 1116
📝 35
Global Marketing Director at
@ionopticks.bsky.social
LC-MS. Chromatography. Tech. Brand. Design.
reposted by
Michael Sinden
IonOpticks
about 1 month ago
Luke Gamon, Asst Prof at
@ucph.bsky.social
, built a spatial proteomics workflow from standard lab equipment: PCR tubes, centrifuges, basic plastics. When a single Aurora column can handle 2,500 injections and still perform, that kind of longevity changes what's feasible. Learn more:
bit.ly/4ulX2XL
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reposted by
Michael Sinden
IonOpticks
about 1 month ago
Rebeca Kawahara was waiting on a competitive fellowship outcome, settled in Australia with two young children. An unexpected offer arrived: to establish a Glycoproteomics Lab in Japan. She took it. 'Sometimes the biggest growth comes from stepping into the unknown.' Read her story:
bit.ly/4oiKhM4
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Written in sugar: Dr Rebeca Kawahara on bringing the glycan code into medicine
Dr Rebeca Kawahara, a glycoproteomics researcher with dual affiliations at Griffith University’s Institute for Biomedicine and Glycomics and the Institute for Glyco-core Research (iGCORE) at Nagoya Un...
https://bit.ly/4oiKhM4
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reposted by
Michael Sinden
IonOpticks
about 1 month ago
Under the warm glow of the San Diego skyline, we welcomed over 230 of you to Deck655 for IonOpticks' annual
#ASMS2026
User Event to close out a massive week of science and innovation. We look forward to inviting you to our next one at
#HUPO2026
in Singapore. Photos from the night:
bit.ly/4afec23
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reposted by
Michael Sinden
IonOpticks
about 1 month ago
NoPro-clipping: a new
@komanderlab.bsky.social
nanoflow LC-MS/MS workflow from
@marcojochem.bsky.social
et al. using an Aurora® Elite™ 15×75 column + Orbitrap Eclipse, Vanquish Neo detects ubiquitination of glycogen, glycerol & spermine in cells & tissues via targeted PRM. Learn more:
bit.ly/3PYs222
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reposted by
Michael Sinden
IonOpticks
about 1 month ago
Next week, Fabrice heads to Yokohama for the 74th MSSJ Annual Conference on Mass Spectrometry, co-exhibiting with our Japanese distribution partner AMR at Stand 17. We're also hosting a Sweets Seminar on Friday 12 June at 02:00pm - a great chance to hear from an expert speaker and enjoy some treats.
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reposted by
Michael Sinden
IonOpticks
about 1 month ago
Please join us in welcoming Mike Baynham to the IonOpticks team as our new Global Product Manager, joining our Global Commercial team. We look forward to the insight, expertise and customer focus Mike will bring as we continue enhancing our product portfolio for researchers around the world.
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
What a way to start this morning. We were pleased to see the room being full, the curiosity palpable, and the discussion lively at our
#ASMS2026
breakfast seminar. If your question wasn't answered, join us at the IonOpticks booth, and hopefully you'll cross paths with the speakers on the floor too.
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
Grateful to everyone who stopped by Haley and Greta’s NanoShield® poster this morning at
#ASMS2026
- the conversations were fantastic. Swing by booth 623 and we'd love to walk you through how NanoShield® delivers near-direct-injection performance while keeping your workflow healthy long-term.
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I’m hiring a Scientific Marketing Lead, LC-MS Proteomics, based in Melbourne. A rare blended role for someone who sits between science and marketing, ideal for a PhD candidate or researcher looking to move from the lab bench to industry. Details:
lnkd.in/e5ZTAFew
about 2 months ago
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
PRESS RELEASE: IonOpticks and
@sciex.bsky.social
announce details of a proposed reseller and co-marketing agreement to unify Aurora Series® XS columns, HeatSync™ temperature control, and SCIEX ZenoTOF systems into performance-aligned proteomics workflows.
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IonOpticks and SCIEX announce future collaboration to deliver complete, high-performance LC-MS proteomics workflows - IonOpticks
The Agreement will bring Aurora Series® XS columns and the HeatSync™ ecosystem to SCIEX’s global commercial channels for ZenoTOF 7600, 7600+, and 8600 systems. FOR IMMEDIATE RELEASE San Diego, CA … Co...
https://ionopticks.com/2026/06/03/ionopticks-and-sciex-announce-future-collaboration-to-deliver-complete-high-performance-lc-ms-proteomics-workflows/
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
A great moment at the Thermo
#ASMS2026
user meeting as Mark Larance from
@sydney.edu.au
highlighted the performance of Aurora® Elite™ 15x75 XT columns in his SCP workflow. Great to see this workflow pushing what's possible in high-throughput single-cell analysis.
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
What a start to
#ASMS2026
! The welcome reception brought a lively crowd to the IonOpticks booth, with strong interest from night one. Our team loved seeing familiar faces and new connections, and we’re keen to keep the conversations going as the week progresses.
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
Kicking off the week of
#ASMS2026
, Haley and Zac joined the Bruker eXceed Symposium, a brilliant one-day deep dive into cutting-edge MS innovation ahead of the main conference. During the breaks, it was great to see our NanoShield® trap column drawing plenty of curious eyes.
#MassSpectrometry
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
And we're off!
#ASMS2026
begins tonight, and we’re excited to be back in San Diego for the biggest mass spec event of the year. Visit
#teamIO
at booth 623, welcome Mike Baynham, see our new NanoShield C18 trap column, grab some signature swag and register for our Wednesday breakfast seminar.
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
Thank you to everyone who joined Dr
@brendonseale.bsky.social
's IonOpticks Insights webinar on scaling core facility proteomics. You can still register to watch it on demand, along with helpful bonus materials, which you can find under "Additional Resources":
bit.ly/3QRnp9T
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
This Thermo Scientific tech note tackles one of immunopeptidomics' toughest challenges: getting meaningful depth from low-level, precious clinical material. The Orbitrap Astral Zoom was paired with a Vanquish Neo and an Aurora® Ultimate™ 25×75 XT column. Read the full tech note:
bit.ly/4xeEdZt
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
We're delighted to welcome
@amandalsmythers.bsky.social
from the Gygi Lab at Harvard Medical School and Dana-Farber Cancer Institute to our
#ASMS2026
breakfast seminar. She'll bring her expertise in phospho DIA on the Astral. Wednesday June 3, 7:00am Breakfast provided Register now:
bit.ly/4dvarXl
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
We're pleased to welcome Denys Oliinyk from the Mann Lab to our
#ASMS2026
breakfast seminar. He'll join a panel discussion spanning single-cell, phospho, and DVP - and what good separation unlocks across these fields. Wednesday, 3 June, 07:00am. Breakfast provided. Register now:
bit.ly/4dvarXl
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
Excited to have
@slavov-n.bsky.social
as a speaker at our
#ASMS2026
Breakfast Seminar. He'll bring his single-cell perspective to a broader conversation about what good separation enables across modern proteomics workflows. Wednesday June 3, 07:00am Breakfast provided Register now:
bit.ly/4dvarXl
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
Traps have long been seen as a trade-off: more robustness, less performance. But what if that compromise was never inevitable? In this opinion piece, Dr Jarrod Sandow explores how NanoShield® C18 trap columns are helping proteomics workflows become both resilient and high-performing:
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Traps: The column companion we misunderstood
Proteomics is evolving rapidly, and as we push toward deeper coverage, higher throughput, and more demanding applications, the expectations placed on our workflows will only increase. Meeting those ex...
https://ionopticks.com/2026/05/25/traps-the-column-companion-we-misunderstood/
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
In highly sensitive immunopeptidomics, confidence in your column matters. Professor Tony Purcell shares how Aurora Series columns support demanding LC-MS workflows with the robustness, sensitivity, longevity and reproducibility researchers need, across Bruker timsTOF and SCIEX ZenoTOF systems.
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IonOpticks and The Purcell Lab: From collaboration to innovation.
YouTube video by IonOpticks
https://www.youtube.com/watch?v=9kQD5qDJ9lI
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
At
#ProteoVilamoura2026
,
@sciex.bsky.social
's Mario Armelao delivered an impressive talk showcasing the low-input capabilities of the ZenoTOF 8600 system, when combined with the Evosep Eno paired with Aurora® Elite™ XS columns.
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
New multi-consortium study developed a framework to classify small proteins ("microproteins"), introducing the term "peptidein" for confirmed translation products whose biological role remains unclear. LC–MS system comprised an Aurora Elite 15×75 XS column + SCIEX ZenoTOF 8600.
bit.ly/3RaIYTj
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
The countdown to
#ASMS2026
has well and truly begun. This year, there’s plenty to discover, from our Wednesday Breakfast Seminar to our poster presentations, seven oral presentation mentions, and more. See everything we're bringing to San Diego:
bit.ly/4urDEtq
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IonOpticks at ASMS 2026: Everything you need to know.
IonOpticks is back for the biggest event on the mass spectrometry calendar: the 74th Annual ASMS Conference in San Diego, California. After another year of product development, customer collaboration,...
https://bit.ly/4urDEtq
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
What a wonderful few days at
#ProteoVilamoura2026
. It was a pleasure for Britta & Joris to represent IonOpticks at this joint meeting, a tightly-knit community of proteomics researchers from Portugal, Spain, and France. It's hard to imagine a better setting for scientific exchange and reconnection.
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
For Dr Aniel Sanchez, proteomics is a way of thinking - one that demands constant reinvention as the science evolves. Now part of the Neil Kelleher group at Northwestern University, Aniel is helping make proteoform-level analysis accessible at a scale that could change how we understand disease.
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How Dr Aniel Sanchez is finding rigour, curiosity, and proteoforms at the frontier of plasma proteomics
Dr Aniel Sanchez has spent his career following the science wherever it leads, rebuilding his thinking each time it takes him somewhere new. From a chemistry lab in Havana to a postdoctoral position i...
https://bit.ly/4uqakDF
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reposted by
Michael Sinden
IonOpticks
about 2 months ago
Five years ago, Francis joined IonOpticks and bumped our Production team from "one and a half" to "two and a half" technicians. With a team that has since expanded ten-fold, Francis has been along for some major growth. Thank you for five years of helping build something we're all proud of.
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reposted by
Michael Sinden
IonOpticks
2 months ago
Fast, sharp, and packed with insight - all before 9am. We're hosting a breakfast seminar at
#ASMS2026
and we're excited to have
@slavov-n.bsky.social
,
@amandalsmythers.bsky.social
, and Denys Oliinyk as our guest speakers. Complimentary breakfast provided Register now:
bit.ly/4dvarXl
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reposted by
Michael Sinden
IonOpticks
2 months ago
@jtrend.bsky.social
et al. demonstrate that UVEN accelerates photo-crosslinking by up to 500-fold compared to conventional UV bulbs. For protein–RNA interactome profiling, the team paired Aurora Ultimate 25x75 columns on a Vanquish Neo with a timsTOF HT. Learn more:
bit.ly/3PFpNQY
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reposted by
Michael Sinden
IonOpticks
2 months ago
We’re back for the biggest event of the year: the 74th
#ASMS2026
Conference - now in San Diego. With two poster presentations, a Breakfast Seminar, a User Appreciation Event, and more, learn more about our presence:
bit.ly/4dvarXl
@asms.org
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reposted by
Michael Sinden
IonOpticks
2 months ago
Introducing our new Troubleshooting Guide, available 24/7. Designed for Aurora Series®, it provides step-by-step diagnostic support tailored to your setup, helping you resolve issues quickly and confidently using workflows built for IonOpticks technology.
www.ionopticks.com/troubleshooting-guide
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reposted by
Michael Sinden
IonOpticks
2 months ago
Register now for IonOpticks’ invite-only ASMS 2026 rooftop celebration at Deck 655, San Diego. Join us Thursday, June 4 from 9:00pm for live entertainment, food, drinks, and music from renowned DJ & saxophonist Tim Lacatena. Spaces are limited. Secure your place today. Link in comments.
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reposted by
Michael Sinden
IonOpticks
2 months ago
Heading to
#ASMS2026
? Don't miss Greta Briedytė's poster TP 400 “Cyclical High-Organic Wash strategies minimise carry-over between LC-MS samples” in Hall ABC on Tuesday 2 June. Stop by and chat to Greta about how smarter wash strategies can keep your high-throughput workflows clean and efficient.
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reposted by
Michael Sinden
IonOpticks
2 months ago
Catch Haley Oller at
#ASMS2026
presenting poster TP 401 'Optimising Trap Column Design for High-Throughput UHPLC–MS Proteomics' on Tuesday 2 June, from 10:30 am – 2:30 pm in Hall ABC. Robust, scalable, and built for the long run. Explore our full scientific presence at ASMS 2026:
bit.ly/4dvarXl
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reposted by
Michael Sinden
IonOpticks
2 months ago
Days left until
#ProteoVilamoura2026
! Stop by our booth and chat to Britta and Joris about how our chromatography, including our newly released NanoShield® C18 trap columns, can enhance your research. We’re proud to support this joint meeting and look forward to connecting with you in Algarve.
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reposted by
Michael Sinden
IonOpticks
2 months ago
El-Baba et al. reveals assembly state of glutamate receptors, over how much a receptor is present, tracks with severe depression in human brain tissue. For crosslinking, peptides were separated on an Aurora Ultimate 25Ă—75 CSI column coupled to a nanoElute 2 and timsTOF Ultra 2. Read:
bit.ly/43fcqdf
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reposted by
Michael Sinden
IonOpticks
2 months ago
NOW PUBLISHED: Hoch et al. research using Aurora Rapid® 8×75 XT columns shows lowering FAIMS resolution on the Orbitrap Astral boosts peptide IDs by 6–18% across 250 pg–16 ng samples, enhancing sensitivity for single-cell proteomics without hardware changes. Read more:
bit.ly/4s0GzHv
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reposted by
Michael Sinden
IonOpticks
3 months ago
Still running strong at injection 4,000 with stable backpressures and consistent retention times across 63 QC runs. This is what column longevity looks like under optimised conditions. Read the app note to see how Aurora Series columns hold up under demanding analytical conditions:
bit.ly/4dRSZxU
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reposted by
Michael Sinden
IonOpticks
3 months ago
Wonderful to be back at Academia Sinica in Taipei, where it’s great to see the proteomics community growing and more researchers working with IonOpticks columns since our visit last year. Thanks to Dr. Shuyu Lin for hosting, and to Mass Solutions Technology for helping to bring these events together
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reposted by
Michael Sinden
IonOpticks
3 months ago
We're proud to have sponsored the 3rd
@ypic.bsky.social
Annual Proteomics Gathering, held last week in Madrid. It was a fantastic opportunity for EC researchers to connect with the wider European proteomics community. Joris was delighted to champion the next generation of proteomics researchers.
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reposted by
Michael Sinden
IonOpticks
3 months ago
Perciaccante et al. develop an integrated LC-MS multi-omics workflow that profiles proteins, lipids, and metabolites from a single sEV sample. Average of 5,623 protein groups IDs from 10 million sEVs with timsTOF Pro, nanoElute 2, & Aurora Ultimate 25x75 CSI column, Learn more:
bit.ly/3QP0CLP
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Preprint: Integrated multi-omics enabled by sequential extraction for comprehensive molecular profiling of small extracellular vesicles - IonOpticks
Perciaccante et al.'s preprint on the molecular profiling of small extracellular vesicles used an Aurora Ultimate 25Ă—75 CSI UHPLC column.
https://bit.ly/3QP0CLP
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reposted by
Michael Sinden
IonOpticks
3 months ago
Analytical column robustness and longevity matter as much as performance. NanoShield® was built for this new reality: trap columns that protect Aurora Series® lifetime while maintaining direct-injection-level performance. Available in 3 packs, explore superior protection:
bit.ly/4tTi68j
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reposted by
Michael Sinden
IonOpticks
3 months ago
Fantastic to be in Korea - Fabrice, our Sales Director, APACI & MEA met with clients of our distribution partner SIG for an intro seminar on Aurora columns. Great to reconnect with familiar faces and welcome new ones at Asan Medical Center, one of Korea's leading academic medical institutions.
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reposted by
Michael Sinden
IonOpticks
3 months ago
Thank you for attending our recent webinar with
@mpibiochem.bsky.social
's Dr Tim Heymann. Didn't get a chance to catch it live? Watch it on demand, along with helpful bonus materials:
bit.ly/4lPxNe1
Next scientific webinar with Dr Brendon Seale on Wednesday, April 29. More details to follow.
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reposted by
Michael Sinden
IonOpticks
3 months ago
We just wrapped up our end-of-Q1 staff showcase. With lots happening, it was great to step back and look at what’s ahead. A highlight was celebrating IonOpticks becoming Great Place to Work® Certified™. More importantly, we spent time reflecting on what got us there, and how we keep building on it.
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reposted by
Michael Sinden
IonOpticks
3 months ago
Kawahara et al. profile the sex-specific N-glycoproteome across 19 mouse tissues using TMT-based quantitative glycoproteomics. 26,800+ glycoforms quantified across ~1,500 glycoproteins using Aurora Ultimate 25x75 column + Vanquish Neo + Orbitrap Exploris 240. Learn more:
bit.ly/4so1FzJ
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Preprint: Multi-omics definition of the sex-specific glycoproteome of murine tissues - IonOpticks
Kawahara et al.'s preprint on the sex-specific glycoproteome of murine tissues used an Aurora Ultimate 25Ă—75 UHPLC column.
https://bit.ly/4so1FzJ
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reposted by
Michael Sinden
IonOpticks
4 months ago
NOW PUBLISHED: Lowering FAIMS resolution on the Orbitrap Astral increases peptide identifications by 6-18% across sample loads from 250 pg to 16 ng, as demonstrated in new research from the Mechtler lab using Aurora Rapid 8Ă—75 XT columns:
bit.ly/4s0GELj
@matzingerm.bsky.social
@impvienna.bsky.social
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reposted by
Michael Sinden
IonOpticks
4 months ago
The
@aktast.bsky.social
lab dismantled nuclear speckles for the first time to probe their role in genome organisation and RNA processing. In global quantitative proteome profiling, peptides were separated on an Evosep One coupled to a timsTOF SCP with Aurora Elite 15x75 CSI columns.
bit.ly/3PTia97
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Nuclear speckles enable processing of RNA from GC-rich isochores
Nuclear speckles are key subnuclear structures that regulate gene expression in GC-rich regions. This work shows that the evolution and expansion of core speckle proteins were crucial for the increase...
https://bit.ly/3PTia97
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reposted by
Michael Sinden
IonOpticks
4 months ago
It's great to see Aurora Series columns featured in Heymann et al.'s new BioRxiv preprint in collaboration with SCIEX - and the results speak for themselves. Congrats to all involved on this milestone.
lnkd.in/gv_9Y3Kc
Want to hear more from Dr. Heymann? Register for our webinar:
bit.ly/4lPxNe1
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