Twas the night before Christmas, and throughout the land The sleeping arrangements were carefully planned Down in the kitchen, a picturesque scene A mattress, a pillow, a washing machine

This remains one of the BEST social media threads of the year. If you've never seen it, check it out (and if you're a long-time duvet-er, enjoy!) 😁

Sad news about #ChrisRea. Was a bit of a fan when I was growing up. Predictable focus on 'Driving home for Christmas'. But it's not even his best Christmas song lol. If you've not heard it, check this. The Intro is 🔥, and the lyrics are top drawer Thanks, Chris. RiP youtu.be/nYz21xcJxTs?...

Just a gentle reminder to anyone who needs this... Please share with your followers. You might be surprised who it could help...

Dear the entire USA. You guys know that this is not normal, right? 🤦‍♂️😬

I have a PhD position available with start date September 2026 at the University of Manchester. Proteomics analysis of flow cytometry-based isolated pathogen-containing phagosomes Due to funding requirements, this position is for UK home students only. www.findaphd.com/phds/project...

2 adjacent papers in my timeline with new AD biomarkers. First claims 'accurate prediction'. Second claims 'prognosic value'. First has an AUC of 0.769. Second has AUC 0.71 [95%CI 0.57–0.85]. Both values from the discovery cohort only. Is it just me, or are these neither accurate or valuable?

This is one of the funniest things I've read in ages... 🤣🤣👏👏

I am looking for a PostDoc to join my group at Genentech to drive the development of proteomics technologies to fuel target and therapeutic discovery and development. Check out the link below! careers.gene.com/us/en/job/20...

The parents of a three-year-old boy born with a devastating, life-limiting genetic condition say they are now excited for his future after he received a revolutionary stem cell gene therapy treatment developed by researchers at the University of Manchester. www.bbc.co.uk/news/article...

Registration for the Round 6 of Mentorship Pods is now OPEN! More info👉 femalesinms.com/mentorship-p... Registration 👉 femalesinms.com/mentorship-p...

This is an outstanding thread, and is spot on... The drive towards open access/data sharing has been driven by funders. They're important, sure, but as an author I consider these more because my funder and employers expect it. The same people can lead to not-for-profit and quality over quantity.

Love being reminded to do this every year. It's a win/win all round

Whinge of the week: So far this week I've read THREE papers where the title claims to have identified and validated novel biomarkers for disease X. Of the three, one is in mice, one is based on a 10 v 10 cohort, and the third has an AUROC of 0.65, falling to below 0.6 in a second cohort.

Daniel Hannan has a self-awareness problem

Well this was kind of inevitable but it still makes for horrible reading. Should mean the back of Chansiri and fresh start, though, if we can find a sale. 🤞🤞😢 🦉🦉🦉 #wawaw #swfc www.bbc.co.uk/sport/footba...

This is accurate. There's a valley of death between 'good academic research' and 'ready for investment'. Every project at that stage is risky, and because there's not much money instututions cherry pick and become risk averse. If you wanna win the lottery, buy more tickets.

🤣🤣🤣 Yup 🎯

Anyone see the attendance tonight? #SHWMID #swfc.

From Manchester for the world. We are proud to launch our bold strategy to 2035. Together, we're redefining what a great civic University looks like for the 21st century. Visit our webpage to explore our ambition in full: www.manchester.ac.uk/about/manche...

ECR with <3yrs postdoc experience? The University of Manchester @officialuom.bsky.social is offering THREE Bicentenary Fellowships. 3yrs salary + £30k pa funding If you have a project involving mass spec, biomarkers and human disease, get in touch! www.bmh.manchester.ac.uk/research/sup...

📣 New MRC DTP PhD project is available with David Brough, Kevin Couper, Roy Ng and Chris Hoyle looking at the NLRP3 inflammasome in the brain and brain disease findaphd.com/phds/project.... Please get in touch if you are interested! 🧠

There is a position open in our lab, within this network. Our project deals with assessing identification and quantification errors for MS-based proteomics. www.protaiomics.eu/project/dc13... Please check out all the project descriptions at the site below:

Holy moly

Interested in establishing your own research group? Our support package for new Group Leaders includes: 🥼2 #Postdocs, a technician & 2 PhD students + lab costs 🔬Full access to core facilities 🧪Access to the MCRC #Biobank ✔️Mentorship, #grant advice & more www.cruk.manchester.ac.uk/career/new-g...

Well this is exciting. From a basic science collaboration with @prof-clark.bsky.social and Paul Bishop, to a spin-out, and now into the clinic. Been some journey. Congratulations to everyone at Complement Therapeutics. This is an outstanding achievement. bit.ly/42w1YhT

🤦‍♂️🤦‍♂️

Finally, we're looking for someone to join our #MassSpec Core Facility to support all the protein/peptide MS & development needs of our research groups utilising: 🧪Protein chemistry 📈Liquid chromatography ⚛️Tandem mass spectrometry 🖥️Data analysis More at: www.cruk.manchester.ac.uk/career/mi-25...

🥳 We have been recognised as one of the best universities in England for intellectual property and commercialisation performance. The Innovation Factory (@uomif.bsky.social) achieved the highest possible rating for IP and Commercialisation.

As someone who relied on a maintenance grant (and no tuition fees) to go to Uni and is now a University Professor, I 100% support this. I hope that the grant is enough to make a difference. I also hope this is one step in a wider programme to support students to fulfil their potential.

We are looking for visionary scientists ready to establish an independent, world-leading research programme & take full advantage of the extraordinary collaborative ecosystem including @mcrcnews.bsky.social @manchester.ac.uk, The Christie NHS Foundation Trust & @cruknbc.bsky.social #OncoSky

Despite repeated attacks on science over the past few days/weeks/months/years from Dumb and Dumber (you know who I mean), this an outstanding example to show that science works - and can do genuinely incredible things... www.bbc.co.uk/news/article...

Postdoc Research Associate vacancy at Imperial College, @ukdri.ac.uk with Dr Samuel Barnes, using multiplexed synaptic proteomics and imaging to study early Alzheimer. Closing date: 1st October www.dementiaresearcher.nihr.ac.uk/job/research...

Oh Dickie Bird. Barnsley Legend. Superstar. Met him once in tarn - lovely man who had time for everyone. May there be no bad light wherever you've gone. RIP.

Guys, we've been doing this all wrong! My next grant application: Dear Donald and Jay, Here's a random idea that I have no actual evidence for whatsoever. BUT this is based on what I feel. Please send $10m forthwith to help with my 'research'. Best A Scientist 🤦‍♂️🤪

Really excited to be part of this project, funded by @parkinsons.org.uk www.parkinsons.org.uk/news/further...

The best time to have done this was a couple of years ago. The next best time is now...

Postdoc position on top glyco-immuno-neuro-biology lab @douglaspdyer.bsky.social Can’t recommend highly enough www.jobs.manchester.ac.uk/Job/JobDetai...

PTI is growing and we are looking for more scientists to join our team! Neurodegenerative Disease Senior Scientist: jobs.lever.co/convergentre... Computational Biologist: jobs.lever.co/convergentre... Research Chemist: jobs.lever.co/convergentre...

It's been bugging me who Trump reminds me of but I've just realised... He writes/speaks like the villian in a Roald Dahl book. Boggis, Bunce, Bean (greedy) Veruca Salt (spoilt) Trunchbull (bully) Sponge and Spiker (cruel) Grand High Witch (power-hungry) Mr and Mrs Twit (petty) I could go on...

A key attack line in the next few years coming from Trump/MAGA and Reform is that university teachers (lecturers/professors) are poisoning the minds of young people, brainwashing them into leftist thinking. Make no mistake, this is a pretext to defund the sector. 1/n

We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...

Boris Johnson's a bit dodgy shock... 🤦‍♂️🤦‍♂️

We are recruiting two biomedical data scientists as part of a new Centre of Research Excellence (MRC CoRE) in Exposome Immunology hosted jointly by @fbmh-uom.bsky.social and @ox.ac.uk. www.jobs.manchester.ac.uk/Job/JobDetai... www.jobs.manchester.ac.uk/Job/JobDetai...

This is completely nuts and people are going to die as a result. What on earth do they hope to gain from this? Horrific.

Nigel Farage looks uncomfortable as Jamie Raskin uses his opening statement to absolutely demolish him

Are you a postdoc interested in the mechanisms of disease? Do you have a great record and an exciting vision? Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships. Deadline 30th September...pass it on! www.path.ox.ac.uk/work-with-us...

This is through the looking glass stuff... 🤦‍♂️