Could folding systems in Clostridia bacteria make ideal drug targets? Cristina Landeta @cris-s.bsky.social takes us behind the scenes of their #Microbiology paper on investigating the machinery that build crucial disulphide bonds in bacterial cells microb.io/4oba348

Our latest work is now published! Please check it out. Congratulations to Adrian, Rebecca and @fireinlab.bsky.social for their hard work. I’m very proud of this piece, we found proteins that require oxidative protein folding in mycobacteria. journals.asm.org/doi/10.1128/...

Great collaboration with my Bloomington colleague @cris-s.bsky.social out now in #mbio #teammassspec journals.asm.org/doi/10.1128/...

Congratulations Manuel and Baizabal lab for this 2025 seed grant from the Brain Research Foundation! 👏🏽🥳 www.thebrf.org/seed-grants/ @iubiology.bsky.social #iu #heterochromatin

Very VERY excited to see this addition to the SCIMaP project. @joshuasweitz.bsky.social @asinclair.bsky.social BOTTOM LINE: Proposed NIH cuts are estimated to result in ~50b in economic losses and over 200k job losses. But hey! How are those egg prices?? scienceimpacts.org/fy26

For non-scientists: the funding rate is somewhere between 7% to ~25% (rare) for NIH or NSF grants, depending on where you are applying. Grants are reviewed by a panel of peers who read the grants, score them, then debate the ratings for 1-2 days to rank them. It is INCREDIBLY competitive already.

I urge others to similarly support our patriots at NIH who use their training and talents to improve human health and position the US as the world’s leader in biomedical discovery, innovation and technology development 🙏

Trump’s NIH cuts aren’t just numbers. They are delayed cures, abandoned treatments, futures stolen, lives that will be lost. This is why we Stand Up For Science. #StandUpForScience #SummerFightForScience

My lab and I attended the VIII Beckwith reunion at Hyannis, MA. Supper happy to see old time friends. It was great to catch up and discuss science, social issues in biology and talk about life!

HAPPY 75th, NSF! We’re celebrating this milestone by highlighting some of NSF’s most transformative accomplishments—innovations that have shaped our world and continue to drive progress in health, technology, the environment, and beyond. Read on 🧵(1/11):

As markets plummet again today from Trump's chaotic economic policies, ask yourself: Why would billionaires back policies that tank their own stock values? It’s the taxes. I wrote a step-by-step explainer of how billionaires avoid paying taxes. People are often surprised when I explain it.🧵

Thanks @standupforscience.bsky.social for organizing! @nytimes.com please report on this, the public deserves to understand how decreasing DEIA and funding in Science will impact them. Thanks @nature.com for live reporting! @goodtroublein.bsky.social @indivisible.org @iubiology.bsky.social

Breaking news: Thousands of researchers and their supporters, including recently fired federal workers, have gathered across the U.S. in response to layoffs and funding cuts ordered by the Trump administration. scim.ag/41zlPv4

Stand up for Science Indianapolis. We need science not trillionaires!

It’s tomorrow!!! we will be in Indianapolis… que se oiga con fuerza: Fund science, not billionaires!

WHERE WILL YOU BE ON MARCH 7TH!? Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one! #standupforscience2025

Spending isn't a “conspiracy” just because Musk doesn’t know how to read usaspending.gov. A program isn't waste just because it doesn’t help the richest man in the world. It isn't fraud just because he doesn’t like it. A law is not illegal just because he disagrees with it.

Love national parks? I'm lucky enough to live in one of the best parks in the world, and on Saturday we held a demonstration to protest the mass & indiscriminate firing of our friends and coworkers. #nationalparks #rangers #publicland #Yosemite #Firefall #fedworkers #massfiring #NPS #ProtectourParks

🚨 WANT TO HELP US STAND UP FOR SCIENCE? 🚨 Here's a little update on where we're currently at with the planning process! Is your state red or grey & you want to see an event happen? Fill out our volunteer form or share with a friend! airtable.com/app4h5wUssMG... #standupforscience2025

Stand up for Science: March 7 🧪 standupforscience2025.org

📢 “He’s trying to steal Medicaid to enrich himself. He’s gutting NASA to line his pockets with SpaceX. He’s looting everything good in America for private profit.” - @aoc.bsky.social at today’s #SaveOurServices NYC rally. The fight isn’t over. Join us: go.savepublicservices.com

This is Oligarchy. The three richest men in the world have become $196 BILLION richer since Donald Trump was elected. $196 billion for three men in 99 days. Meanwhile, 60% of Americans live paycheck to paycheck.

Make sure you, your trainees, and anyone else who might listen to you understands what "indirects" actually are, how they are established, and what Universities contribute. H/T @rodallab.bsky.social Please share widely! www.youtube.com/watch?v=yxTD...

At least $12 *trillion* from global oligarchs is hidden offshore in secret tax havens worldwide. And it is headquartered right here in the USA. Instead of cutting lifesaving programs like the VA, Medicaid, and food stamps, we should be cracking down on tax havens for the ultra-rich.

Our preprint is live now! We identified substrates of oxidative protein folding in mycobacteria… myco is interesting, so many essential proteins.