Michael Lustgarten, PhD
@conquer-aging-123y.bsky.social
š¤ 46
š„ 12
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Scientist
New YT video!
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Using Correlations To Improve Biomarkers (Test #7 In 2025)
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=cI5HQ7cHpWk&t=1s
2 days ago
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reposted by
Michael Lustgarten, PhD
Aging Science News
8 days ago
The inflammation-aging axis: Shared and distinct mechanisms in physiological gut aging and IBD-associated accelerated gut aging
www.jstage.jst.go.jp/article/bst/...
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The inflammation-aging axis: Shared and distinct mechanisms in physiological gut aging and IBD-associated accelerated gut aging
Inflammatory bowel disease (IBD) and physiological gut aging present with overlapping clinical features, including impaired barrier functioning, decre ā¦
https://www.jstage.jst.go.jp/article/bst/advpub/0/advpub_2025.01279/_article
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reposted by
Michael Lustgarten, PhD
Aging Science News
9 days ago
Reversing lysosomal dysfunction restores youthful state in aged hematopoietic stem cells
www.cell.com/cell-stem-ce...
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Reversing lysosomal dysfunction restores youthful state in aged hematopoietic stem cells
Arif et al. show that lysosomes in aged HSCs are hyperacidic and dysfunctional, and that lysosomal alterations are central to HSCsā decline with age. cGAS-STING signaling, driven by misprocessed mtDNA...
https://www.cell.com/cell-stem-cell/abstract/S1934-5909(25)00405-9?rss=yes&utm_medium=twitter&utm_source=dlvr.it
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New video!
www.youtube.com/watch?v=-MTm...
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Who's Really Winning At Longevity? (Featuring @Unaging.Crissman.Loomis)
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=-MTmYomgmes
9 days ago
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reposted by
Michael Lustgarten, PhD
Aging Science News
13 days ago
Mitochondrial Respiratory Supercomplex Assembly Factor COX7RP Contributes to Lifespan Extension in Mice
onlinelibrary.wiley.com/doi/10.1111/...
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Mitochondrial Respiratory Supercomplex Assembly Factor COX7RP Contributes to Lifespan Extension in Mice
Mitochondrial respiratory supercomplex assembly factor COX7RP improves metabolic homeostasis and contributes to lifespan extension in mice. The overexpression of COX7RP reduces white adipose tissue m...
https://onlinelibrary.wiley.com/doi/10.1111/acel.70294
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reposted by
Michael Lustgarten, PhD
Eric Topol
17 days ago
How a mattress sensor and smartwatch confirmation led to a patient's diagnosis of complete heart block and need for a pacemaker
@nejm.org
www.nejm.org/doi/full/10....
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New video!
www.youtube.com/watch?v=qKAj...
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If We Escape Age-Related Disease, Motor Unit Loss Will Shorten Lifespan
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=qKAjIbAzo5E&t=1s
16 days ago
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New YT video!
www.youtube.com/watch?v=poEP...
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If We Escape All Major Diseases, Neurodegeneration And Respiratory Failure Is Likely
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=poEP7cQBCn4
23 days ago
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reposted by
Michael Lustgarten, PhD
Conor Browne
25 days ago
As I've said before, the distinction drawn between acute infectious diseases and chronic diseases is, in many cases, artificial. This is the huge flaw in MAHA: infections can and often do cause chronic disease; vaccines can thus prevent some chronic diseases.
stanmed.stanford.edu/infections-l...
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Why acute infections can lead to neurodegeneration
Researchers are uncovering the mysteries of why early-in-life acute infections can lead to neurodegenerative diseases in later years.
https://stanmed.stanford.edu/infections-link-later-life-neurodegeneration/
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www.youtube.com/watch?v=yNbX...
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Carotenoids Are Associated With A Younger Biological Age
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=yNbXCzQB8hY
25 days ago
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Ner YT video!
www.youtube.com/watch?v=0zPc...
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The Waist-To-Hip RatioModifies LP(a)-Associated CVD Risk
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=0zPcCocwI5o
27 days ago
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New YouTube video!
www.youtube.com/watch?v=1N1w...
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Glucagon Signaling Is Required For The Lifespan Extending Effect Of Calorie Restriction
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=1N1wI1tTzwI
about 1 month ago
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New YT video!
www.youtube.com/watch?v=bUh7...
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Diet Composition That Corresponds To A 17y Younger Biological Age (Test #6 In 2025 Deep Dive)
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=bUh7icfos-E
about 1 month ago
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New YT video!
www.youtube.com/watch?v=hrVE...
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Optimizing Vitamin D, NAD, Homocysteine (Test #6 In 2025 Analysis)
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=hrVEWDySqA4
about 1 month ago
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Tracking Every Biomarker: Inside Dr. Lustgartenās Data-Driven Blueprint for Longevity
youtube.com/watch?v=agwn...
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http://youtube.com/watch?v=agwnE_Z6edk
about 2 months ago
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reposted by
Michael Lustgarten, PhD
Aging Science News
about 2 months ago
Glucagon receptor signaling is indispensable for the healthspan effects of caloric restriction in aging male mice
link.springer.com/article/10.1...
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Glucagon receptor signaling is indispensable for the healthspan effects of caloric restriction in aging male mice - GeroScience
Obesity and type 2 diabetes mellitus accelerate aging, shortening the duration of healthspan. Conversely, chronic calorie restriction (CR) extends healthspan. Research aimed at understanding the mecha...
https://link.springer.com/article/10.1007/s11357-025-01899-w
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New YT video!
www.youtube.com/watch?v=IuXT...
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Reducing Cardiovascular Disease Risk: Going Beyond ApoB
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=IuXTPRx6xQQ
about 2 months ago
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New YT video!
www.youtube.com/watch?v=tEaS...
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How To Track And Optimize Biomarkers: Blood Test #6 in 2025
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=tEaS6_7gnn4
about 2 months ago
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New YT video!
www.youtube.com/watch?v=2_qS...
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What's The Biochemistry Of Fitness In 80yr Olds?
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=2_qSZBMK478
2 months ago
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reposted by
Michael Lustgarten, PhD
Aging Science News
2 months ago
Roles of plasminogen activator inhibitor-1 in aging-related muscle and bone loss in mice
www.aging-us.com/article/2063...
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Roles of plasminogen activator inhibitor-1 in aging-related muscle and bone loss in mice | Aging
Aging | doi:10.18632/aging.206318. Takashi Ohira, Naoyuki Kawao, Yuya Mizukami, Kiyotaka Okada, Akihito Nishikawa, Hisatoshi Yamao, Ayaka Yamada, Hiroshi Kaji
https://www.aging-us.com/article/206318/text
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New video!
www.youtube.com/watch?v=zOi_...
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Fine Particulate (PM2.5) Exposure Negatively Impacts Hallmarks Of Aging: What's Optimal?
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=zOi_FjhZplY&t=1s
2 months ago
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New YT video!
www.youtube.com/watch?v=DjtG...
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Phosphatidylcholines Are Biomarkers Of The Omega-3 Index
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=DjtG9rODWLo&t=1s
3 months ago
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www.youtube.com/watch?v=end9...
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Nectandrin B (Found In Nutmeg) Extends Lifespan As Much As Rapamycin
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=end9J9P7dGw
3 months ago
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New YT video!
www.youtube.com/watch?v=99cO...
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Is Nicotinic Acid Bad For Longevity?
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=99cOA2SRNuc
3 months ago
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Blood Test #6 in 2025 Results Are In!
www.patreon.com/posts/blood-...
3 months ago
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Hot off the presses (note the author list)! METABOLOMIC SIGNATURES OF EXTREME OLD AGE: FINDINGS FROM THE NEW ENGLAND CENTENARIAN STUDY
www.biorxiv.org/content/10.1...
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METABOLOMIC SIGNATURES OF EXTREME OLD AGE: FINDINGS FROM THE NEW ENGLAND CENTENARIAN STUDY
The New England Centenarian Study (NECS) provides a unique resource for the study of extreme human longevity (EL). To gain insight into biological pathways related to EL, chronological age and surviva...
https://www.biorxiv.org/content/10.1101/2025.09.10.675341v1
3 months ago
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reposted by
Michael Lustgarten, PhD
Aging Science News
3 months ago
Japan sets record of nearly 100,000 people aged over 100
www.bbc.co.uk/news/article...
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Japan sets new record with nearly 100,000 people aged over 100
The number of Japanese centenarians rose to 99,763 in September, with women making up 88% of the total.
https://www.bbc.co.uk/news/articles/cd07nljlyv0o
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New YT video!
www.youtube.com/watch?v=M6t_...
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Higher HRV, Lower RHR: 2,577 Days Of Tracking
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=M6t_b6DuWIA
3 months ago
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New YT video!
www.youtube.com/watch?v=MoAT...
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Diet, Supplements Of A Longevity Scientist (Blood Test #5 In 2025)
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=MoATyohDHRU
3 months ago
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New YT video (clip)!
www.youtube.com/watch?v=P-Jf...
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Defining Immune Health: Whatās Optimal For CD4 And CD8 Cells?
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=P-JfVFV0T48&t=1s
4 months ago
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New YT video!
www.youtube.com/watch?v=OhR2...
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Cardiovascular Disease Risk Biomarker Analysis (70+ Tests Since 2005)
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=OhR2-Y743wE&t=1s
4 months ago
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New video (clip)!
www.youtube.com/watch?v=nvFz...
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The Top 10 Micronutrients For Aging Well (Featuring Emily Ho, PhD)
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=nvFzwOArZo8
4 months ago
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New YT video!
www.youtube.com/watch?v=7WMG...
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Attempting To Slow Aging By Optimizing Biomarkers
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=7WMGOnK99Hw
4 months ago
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New YT video!
www.youtube.com/watch?v=lyDg...
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Immune Resilience And The 15-Year Survival Advantage: Sunil Ahuja, M.D.
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=lyDgEFeUP0s
4 months ago
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New YT video!
www.youtube.com/watch?v=D1LV...
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Can Dietary Sodium Reduce Grey Hair?
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=D1LVLql2xZ4
5 months ago
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New YT video!
www.youtube.com/watch?v=Zm2K...
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Aging Well And Optimal Health: Role Of Nutrition (Featuring Emily Ho, PhD)
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=Zm2KgkdiOAA
5 months ago
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New YT video!
www.youtube.com/watch?v=8ewO...
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Reversing The Age-Related DHEA-S Decline: Cholesterol, Gut Bacteria
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=8ewO9IS8p0A
5 months ago
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reposted by
Michael Lustgarten, PhD
John F. Cryan
5 months ago
Some gut microbes can absorb and help expel āforever chemicalsā from the body, research shows
www.theguardian.com/environment/...
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Some gut microbes can absorb and help expel āforever chemicalsā from the body, research shows
Previously, the only way to reduce levels of Pfas was by bloodletting or a drug with unpleasant side effects
https://www.theguardian.com/environment/2025/jul/13/pfas-gut-microbes-forever-chemicals?utm_source=dlvr.it&utm_medium=bluesky&CMP=bsky_gu
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New YT video!
www.youtube.com/watch?v=HQxf...
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17y Younger Biological Age (Test #4 in 2025): Supplements, Diet
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=HQxfWGHU66Y&t=1s
5 months ago
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reposted by
Michael Lustgarten, PhD
Celtic Karla
5 months ago
#sciencejobs
add a skeleton here at some point
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reposted by
Michael Lustgarten, PhD
Eric Topol
5 months ago
Why happens when you put SARS-CoV-2 in with human neural (retinal) tissue in culture (organoid)? It induces Alzheimerās-like pathology.
www.science.org/doi/10.1126/...
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Does Nighttime CO2 Impact Sleep?
www.patreon.com/posts/does-n...
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Does Nighttime CO2 Impact Sleep? | Michael Lustgarten, PhD
Get more from Michael Lustgarten, PhD on Patreon
https://www.patreon.com/posts/does-nighttime-133502379?utm_medium=social&utm_source=twitter&utm_campaign=postshare_creator&utm_content=join_link
5 months ago
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New YT video!
www.youtube.com/watch?v=bAWM...
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Blood Test #62 Since 2015: Full Test Results, Interpretation
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=bAWMFFWCsbk
5 months ago
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www.youtube.com/watch?v=15eX...
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The Gut-Muscle Axis with Dr. Michael Lustgarten @conqueragingordietrying123
YouTube video by Longevity Roadmap
https://www.youtube.com/watch?v=15eXov16K-s
6 months ago
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June 2025 Biomarker Averages: HRV-RHR, BP, Body Weight, Sleep, Immune Activation
www.patreon.com/posts/june-2...
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June 2025 Biomarker Averages: HRV-RHR, BP, Body Weight, Sleep, Immune Activation | Michael Lustgarten, PhD
Get more from Michael Lustgarten, PhD on Patreon
https://www.patreon.com/posts/june-2025-hrv-bp-132983663?utm_medium=social&utm_source=twitter&utm_campaign=postshare_creator&utm_content=join_link
6 months ago
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New YT video!
www.youtube.com/watch?v=aYEu...
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Blood Test #4 in 2025: 17y Younger Biological Age
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=aYEuNS-RI5Q&t=1s
6 months ago
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reposted by
Michael Lustgarten, PhD
Aging Science News
6 months ago
CD38-Targeting Peptide Vaccine Ameliorates Aging-Associated Phenotypes in Mice
onlinelibrary.wiley.com/doi/full/10....
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https://onlinelibrary.wiley.com/doi/full/10.1111/acel.70147?campaign=wolearlyview
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New YT video!
www.youtube.com/watch?v=dWsM...
6 months ago
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New YT video!
www.youtube.com/watch?v=Iu_Y...
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Mushrooms Are Associated With A Younger Biological Age
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=Iu_Yr13fHUo
6 months ago
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New YT video!
www.youtube.com/watch?v=49SW...
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Low Uric Acid Is Associated With A Higher Odds Of Living To 100y
YouTube video by Conquer Aging Or Die Trying! Mike Lustgarten, PhD
https://www.youtube.com/watch?v=49SWt225dTY
6 months ago
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