Aoife O'Farrell
@aofarrell.bsky.social
📤 45
📥 99
📝 2
BioE PhD at UPenn 🏳️🌈🇮🇪
reposted by
Aoife O'Farrell
PennMedCSO
5 days ago
A new paper out in
@natmethods.nature.com
introduces NimbusImage, a cloud-computing platform for image analysis ft. William Niu (SAS), Jingxin Li (
@cambupenn.bsky.social
),
@aofarrell.bsky.social
(Bioengineering) &
@arjunraj.bsky.social
(
@penngenetics.bsky.social
)
www.nature.com/articles/s41...
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Aoife O'Farrell
Nature Microbiology
about 1 month ago
#Review
Bacteria can “remember” past environments through genetic & biochemical imprints helping them adapt and thrive! 🦠🧠
#MicroSky
www.nature.com/articles/s41...
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Exploring the concept of bacterial memory - Nature Microbiology
This Perspective discusses the concept, mechanisms and evidence for memory in bacteria at individual and community levels.
https://www.nature.com/articles/s41564-025-02185-3?utm_source=bluesky&utm_medium=social&utm_campaign=nmicrobiol
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reposted by
Aoife O'Farrell
Beyond X&Y
3 months ago
It's the scientific community's duty to fight misinformation, bioessentialism, and eugenics That's why we're launching Beyond X&Y, an educational campaign combating the rise of unscientific political propaganda used to attack trans and intersex people Subscribe to our newsletter at
beyondxandy.org
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reposted by
Aoife O'Farrell
Arjun Raj
4 months ago
My great pleasure to introduce DR. Aoife O’Farrell!! An incredible scientist and human being.
@aofarrell.bsky.social
not only produced an amazing thesis by her own sheer brilliance and will, but also provided tireless service to Penn Bioengineering. Will be sorely missed!
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reposted by
Aoife O'Farrell
Vinay Ayyappan
5 months ago
[0/8] Stoked to share our work with
@arjunraj.bsky.social
on tissue organization in the gastruloid. We use lineage tracing and spatial transcriptomics to show that diversity among stem cell clones promotes, rather than hinders, gastruloid development:
www.biorxiv.org/content/10.1...
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Gastruloid patterning reflects division of labor among biased stem cell clones
Embryonic development typically requires precise coordination among cells to achieve reproducible outcomes, leading to the assumption that cellular heterogeneity must be minimized or buffered against....
https://www.biorxiv.org/content/10.1101/2025.07.12.664536v1
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reposted by
Aoife O'Farrell
Stand Up for Science!
7 months ago
HAPPY PRIDE 🏳️🌈 Under Trump, research using terms like “Trans,” “LGBTQ,” & “Gender identity” is being defunded. These terms reflect real people who deserve science that includes them. Stand with us to protect LGBTQ+ science from political erasure.
grant-watch.us/nih-data.html
@rcmedphys.bsky.social
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reposted by
Aoife O'Farrell
The Irish Times
7 months ago
How KJ made medical history: baby healed with world’s first personalised gene-editing treatment
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How KJ made medical history: baby healed with world’s first personalised gene-editing treatment
KJ’s treatment offers a new path for companies to develop personalised treatments without going through years of expensive development and testing
https://www.irishtimes.com/health/your-wellness/2025/05/16/how-kj-made-medical-history-baby-healed-with-worlds-first-personalised-gene-editing-treatment/?utm_source=dlvr.it&utm_medium=bluesky
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reposted by
Aoife O'Farrell
eartha mae
10 months ago
My speech for the Philly
#StandUpForScience
Protest. Everything I do is for my community 💜✨
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#standupforscience2025
10 months ago
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reposted by
Aoife O'Farrell
Shweta Ramdas
12 months ago
Our mentor Casey Brown, apart from being an extraordinary scientist, was a brilliant teacher who loved everything genetics. In his honor, some of the world's leading experts came together to create the 'Casey Brown Lecture Series' on human genetics 1/
shorturl.at/eCm7S
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Casey Brown Lecture Series - YouTube
https://shorturl.at/eCm7S
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reposted by
Aoife O'Farrell
Kat Mayer-Barber,PhD
about 1 year ago
Best
#Nikolaus
🎅! Our paper on how the 🫁 microenvironment can shape
#innate
immunity against
#viruses
is out
@sciimmunology.bsky.social
This was a herculean effort brilliantly led by
@pauljbaker.bsky.social
who singlehandedly established the model in the lab during the pandemic. 🧪
#Immunosky
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reposted by
Aoife O'Farrell
Arjun Raj
about 1 year ago
Science is big enough (especially biomedical) that you have the opportunity to shape your project to match as many of your innate talents, passions, and proclivities as possible. Highly encourage leaning into those strengths when you choose a project:
rajlaboratory.blogspot.com/2024/06/proj...
add a skeleton here at some point
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reposted by
Aoife O'Farrell
The Lewis Lab
about 1 year ago
How do cells remember transient signals? New work reveals that a transient pulse of histone deacetylase inhibition leaves a lasting mark on 3D genome architecture in mESCs, linking chromatin dynamics to cellular memory and gene expression robustness.
www.biorxiv.org/content/10.1...
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reposted by
Aoife O'Farrell
Kimberly Kline 🏔
about 1 year ago
This drug repurposing project for the clearance of intracellular pathogens - led by
@ronni.bsky.social
- is now published in ASC Infectious Diseases. 🤩
pubs.acs.org/doi/10.1021/...
add a skeleton here at some point
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