Tomás Di Domenico
@tdido.eu
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Bioinformatics and Scientific Computing at
@bioinformatics.cnio.es
,
@cniostopcancer.bsky.social
reposted by
Tomás Di Domenico
BSC-CNS
1 day ago
🌐Alfonso Valencia sobre la nueva función de
#OpenAI
con la que impulsa a sus usuarios a compartir su historia clínica con
#ChatGPT
: "Va a cometer errores, a generar malas interpretaciones y a poner al doctor en una posición complicada".
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Tomás Di Domenico
Chanda Prescod-Weinstein 🌌
5 days ago
FOR THE LOVE OF ALL THAT IS GOOD IN THE UNIVERSE PLEASE DO NOT USE THIS THANK YOU FOR YOUR ATTENTION TO THIS MATTER
www.theverge.com/ai-artificia...
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OpenAI launches ChatGPT Health, encouraging users to connect their medical records
But it’s ‘not intended for diagnosis or treatment.’
https://www.theverge.com/ai-artificial-intelligence/857640/openai-launches-chatgpt-health-connect-medical-records
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Tomás Di Domenico
22 days ago
These days CNIO personal spontaneusly decorate corridors, labs, the cafeteria... And some of them have even shared ther musical talent in the first New Year Concert, filled with best wishes for the Christmas Season and for 2026 ✨ More info:
https://bit.ly/3KJJW69
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Tomás Di Domenico
CNIO Bioinformatics Unit
about 2 months ago
#PorLaCiencia
que hacemos en
@cniostopcancer.bsky.social
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Tomás Di Domenico
CNIO Bioinformatics Unit
about 2 months ago
#PorLaCiencia
que hacemos en
@cniostopcancer.bsky.social
.
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Tomás Di Domenico
CNIO Bioinformatics Unit
about 2 months ago
📣 We are hiring a Postdoc in
@bioinformatics.cnio.es
at
@cniostopcancer.bsky.social
! 🔬 Cancer genomics, NGS, single-cell & spatial transcriptomics 💻 R/Bioconductor, Python, Linux HPC 🇬🇧 Fluent English 📩 Send your CV with Ref: AIPOSBIOINFCAM25II to
[email protected]
ℹ️ Full info:
tinyurl.com/4hcskvtt
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Postdoctoral Research Assistant for the Bioinformatics Unit
DescripciónThe Bioinformatics Unit within the Cancer Genomics programme is seeking to recruit a highly motivated and talented post-doctoral bioinformatician. The selected candidate will work in the co...
https://www.cnio.es/empleo/postdoctoral-research-assistant-for-the-bioinformatics-unit-aiposbioinfcam25ii/
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Tomás Di Domenico
Stephen Turner
2 months ago
The Drain of Scientific Publishing
arxiv.org/abs/2511.04820
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Tomás Di Domenico
Champi
3 months ago
🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch! 📅 Starting date early 2026, with some flexibility. 🙏Please, RT!
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Tomás Di Domenico
3 months ago
La 'biología del big data' ya ajusta más las terapias a cada paciente. 300 especialistas han presentado sus últimos avances en las XV Jornadas de Bioinformática #JBI2025 (Madrid). Organizadores:
@bioinformatics.cnio.es
, INB/ELIXIR-ES
@cnb-csic.bsky.social
y
@biodata.pt
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La revolución de la bioinformática: descifrar el código de la vida para hacer realidad la medicina personalizada
En biología, descubrir ya no es lo que era. La investigación húmeda, de microscopio y pipeta, ya casi no existe sin la de silicio: programas informáticos que extraen la información oculta en un mar de datos. Esta disciplina en auge, la bioinformática, es la que ayuda a entender qué hace cada variante genética, cada proteína: […]
http://bit.ly/3X0O7wD
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Tomás Di Domenico
EMBL-EBI
3 months ago
Learn more in the open access Nature Genetics paper:
www.nature.com/articles/s41...
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Complete genome assemblies of two mouse subspecies reveal structural diversity of telomeres and centromeres - Nature Genetics
Telomere-to-telomere assemblies of two mouse inbred strains, C57BL/6J and CAST/EiJ, offer improvements over the current mouse reference genome by adding telomere and centromere sequences that lead to ...
https://www.nature.com/articles/s41588-025-02367-z
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Tomás Di Domenico
Stephen Turner
3 months ago
What a time to be alive
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Tomás Di Domenico
3 months ago
La Fundación Instituto Roche ofrece 4 becas de formación para cursar este máster. Suponen el 80% de la matrícula y este año las han conseguido David Dueñas, Jorge Santos, Mario López y Sofía Trigo. ¡Enhorabuena!
#CienciaDatosMPP
#MPP
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El máster que ha impulsado la bioinformática en España se enfoca en la medicina personalizada de precisión
Todos los avances médicos y de investigación de las últimas décadas se sustentan sobre una capacidad humana recientemente adquirida: extraer información valiosa de cantidades ingentes de datos. Es lo que hace la bioinformática, en sí misma un área de investigación cada vez más importante y que en los últimos años también crece de forma sinérgica […]
http://bit.ly/3WncZ1z
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Tomás Di Domenico
BSC-CNS
3 months ago
🔘Nueva edición del Máster de Bioinformática del BSC,
@cniostopcancer.bsky.social
,
@saludisciii.bsky.social
ciii.bsky.social
y SEBiot ▶ Codirigido por Fatima Al-Shahrour y
@alfonsovalencia.bsky.social
, es el segundo en el mundo con la certificación de la
@iscb.bsky.social
➡
lnkd.in/gQcwWzi
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Tomás Di Domenico
MRC Laboratory of Molecular Biology
3 months ago
John Gurdon, former Group Leader and Head of
@cellbiol-mrclmb.bsky.social
has died. Despite calling himself a "total non-intellectual” his work to reprogramme somatic cells to pluripotent stem cells transformed the field of developmental biology. More:
www2.mrc-lmb.cam.ac.uk/john-gurdon-...
#LMBNews
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Tomás Di Domenico
Roger Castells
3 months ago
We’re looking for an enthusiastic postdoc to join our team. 😊 The project focuses on protein design and cryo-EM applied to cancer research. 🔬🧪 The position is fully funded for 3 years. Please share 🙏 Job description and application details (deadline: October 11th):
www.cnio.es/en/empleo/po...
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Postdoctoral Research Assistant for the Biomolecular Design and Structural Nanomedicine Group
DescriptionWe are looking for a Postdoctoral Researcher to join Roger Castells-Graells’ lab at the Spanish National Cancer Research Centre (CNIO). The successful candidate will work on innovative biom...
https://www.cnio.es/en/empleo/postdoctoral-research-assistant-for-the-biomolecular-design-and-structural-nanomedicine-group-aibdsn2-2/
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Tomás Di Domenico
CNIO Bioinformatics Unit
4 months ago
⏰ ¡Última semana para inscribirse en el Máster de Bioinformática del ISCIII! ¡Aún estas a tiempo! ℹ️
masterbioinformatica.com
📌 Organizado por el
@saludisciii.bsky.social
@cniostopcancer.bsky.social
@bsc-cns.bsky.social
🏅 Acreditación oficial
@iscb.bsky.social
🤝 Colaboran SEBiot e Instituto Roche
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Tomás Di Domenico
Andrej Spiridonov
5 months ago
The grave risks for science as the whole of leaving fundamental scientific infrastructure in the hands of for-profit capitalist company. Essential scholarly services should be internationally curated by value-based societies/orders/colleges. 🧪
add a skeleton here at some point
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Tomás Di Domenico
hpc.social on BlueSky
5 months ago
New #HPC Job! 😎️
HPC Engineer
Location: Madrid, Spain Employer: Spanish National Cancer Research Centre Remote: Remote friendly
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If you ever thought banking apps blocking you if you don't have a Google account was frustrating, imagine a world where the EU blocks you from accessing resources unless you accept Google's ToS...
github.com/eu-digital-i...
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Do not add Google Play Integrity integration · Issue #10 · eu-digital-identity-wallet/av-app-android-wallet-ui
In the README, the following is listed: App and device verification based on Google Play Integrity API and Apple App Attestation I would like to strongly urge to abandon this plan. Requiring a depe...
https://github.com/eu-digital-identity-wallet/av-app-android-wallet-ui/issues/10
6 months ago
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At
@bioinformatics.cnio.es
, we're looking for an HPC engineer to help us boost the scientific computing infrastructure at
@cniostopcancer.bsky.social
. Apply or get in touch for more details!
www.cnio.es/empleo/advan...
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Advanced Degree for the Bioinformatics Unit
DescripciónThe Bioinformatics Unit within the Cancer Genomics programme is seeking to recruit a highly a highly motivated and talented High-Performance Computing (HPC) expert specialized in scientific...
https://www.cnio.es/empleo/advanced-degree-for-the-bioinformatics-unit-tsbioinf33/
6 months ago
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Tomás Di Domenico
CNIO Bioinformatics Unit
6 months ago
🔔 Abierto el 2º plazo de preinscripción del Máster en Bioinformática del ISCIII 🧬 Aún nos quedan plazas...¡pero son limitadas! 📆 ¡No pierdas la oportunidad! ¡Aún estás a tiempo! 📚 Organizado por
@saludisciii.bsky.social
@cniostopcancer.bsky.social
@bsc-cns.bsky.social
👉
masterbioinformatica.com
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Tomás Di Domenico
Carl T. Bergstrom
7 months ago
A few months ago, Nature published how-to guide for using ChatGPT to write your peer reviews in 30 minutes. This is, of course, a horrible idea. Here’s my response with
@jbakcoleman.bsky.social
.
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AI, peer review and the human activity of science
When researchers cede their scientific judgement to machines, we lose something important.
https://www.nature.com/articles/d41586-025-01839-w
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Tomás Di Domenico
James Vincent
8 months ago
clear, depressing set of observations from
@randomwalker.bsky.social
- "The decline of reading-for-pleasure (due to video) and reading-for-information (due to AI) will accelerate each other, as reading text without an intermediary will come to be seen as a chore."
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Tomás Di Domenico
Navin B. Ramakrishna
8 months ago
Glad to see this out, and to have contributed in a miniscule way to what will hopefully be an excellent resource: long read assemblies of 17 strains of mice
www.biorxiv.org/content/10.1...
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The mouse pangenome reveals the structural complexity of the murine protein coding landscape
We present the first mouse pangenome consisting of 17 high-quality inbred mouse strain genomes with complete annotation. This collection includes 12 widely used classical laboratory strains and 5 wild...
https://www.biorxiv.org/content/10.1101/2025.05.13.653481v1
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Tomás Di Domenico
CNIO Bioinformatics Unit
8 months ago
¡Abierta la preinscripción del Máster en Bioinformática y Ciencias de Datos en Medicina Personalizada de Precisión y Salud 2025/26! 📍Organizan:
@saludisciii.bsky.social
@cniostopcancer.bsky.social
@bsc-cns.bsky.social
🤝 Colaboran: SEBiot,Instituto Roche 📅 Plazas limitadas 🔗
masterbioinformatica.com
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Tomás Di Domenico
CNIO Bioinformatics Unit
9 months ago
🚀 Registration and abstract submissions are NOW OPEN for
#JBI2025
! 🗓️ Oct 22–24, 2025, in Madrid, Spain 🤝 Spain and Portugal
#Bioinformatics
and
#ComputationalBiology
communities 📰 Submit your work: abstract for talk/poster and highlight papers 🔗
jbi2025.cnb.csic.es
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I started experimenting with
@nanoporetech.com
long-read sequencing technology more than 10 years ago. A couple of years back it became my main focus, and we finally have our first results out:
www.medrxiv.org/content/10.1...
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Multi-Omic Profiling Reveals Epigenetic Drivers of Immunotherapy Resistance in Multiple Myeloma
Targeted immunotherapies against B-cell maturation antigen (BCMA) have transformed the treatment landscape of Multiple Myeloma (MM). Fc receptor-like 5 (FCRL5) has emerged as an alternative target. Ho...
https://www.medrxiv.org/content/10.1101/2025.04.15.25325788v1
9 months ago
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When the first (promising) image-generating models appeared a few years ago I thought that maybe ~10 years later we'd be able to prompt our way into fixing the disaster that Episode IX was. I think my prediction may not be too far off.
10 months ago
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"We estimate the supply-side value of widely-used OSS is $4.15 billion, but that the demand-side value is much larger at $8.8 trillion. We find that firms would need to spend 3.5 times more on software than they currently do if OSS did not exist."
simonwillison.net/2025/Mar/26/...
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A quote from Manuel Hoffmann, Frank Nagle, Yanuo Zhou
We estimate the supply-side value of widely-used OSS is $4.15 billion, but that the demand-side value is much larger at $8.8 trillion. We find that firms would need to spend …
https://simonwillison.net/2025/Mar/26/value-of-open-source/#atom-everything
10 months ago
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As a kid I learned about extinction through dodos. I use "Where are the dodos?" as first contact with every new LLM I try. When I read about
@simonwillison.net
's cycling pelicans benchmark, I decided to try my own: juggling dodos. Then I asked Claude for a gallery to display them:
dodos.tdido.eu
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Juggling Dodos Gallery
https://dodos.tdido.eu
10 months ago
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Tomás Di Domenico
Simon Willison
11 months ago
Quick TIL: if you have uv installed and you want to try out ANY Python package in an ipython REPL, you can do so just by running uvx --with llm --with sqlite-utils ipython Pass as many --with package options as you like I wrapped it in a shell script, "itry llm"
til.simonwillison.net/python/itry
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Trying out Python packages with ipython and uvx
I figured out a really simple pattern for experimenting with new Python packages today:
https://til.simonwillison.net/python/itry
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Tomás Di Domenico
Arvind Narayanan
11 months ago
One of the biggest areas of AI hype right now is the notion that it will hyperaccelerate scientific progress. I understand why people think this — AI is already accelerating scientific _production_. 🧵
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Tomás Di Domenico
Simon Willison
11 months ago
If you have uv installed this means you can start chatting with a small model without first installing anything at all - this command will create an ephemeral virtual environment, install the necessary pieces and start a chat UI running in your terminal: uvx --with llm-smollm2 llm chat -m SmolLM2
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