Lesion network mapping (LNM) links symptoms to brain circuits, but isolating symptom-specific effects remains challenging. We introduce robust LNM, a unified framework to reveal reliable, symptom-specific networks. biorxiv.org/content/10.64898/2026.05.18.725812v2

🧠 I'm so happy to share our personalized circuit-guided neuromodulation targeting platform UNITE, led by @weizhangvvv.bsky.social, is out in Nature Protocols @natureportfolio.nature.com ! 📄 Protocol: nature.com/articles/s41... 🔬 Nature: nature.com/articles/s41...

Thrilled to announce our new paper in @natneuro.nature.com! We managed the impossible: precision functional mapping during #DBS, with 11.7h fMRI/patient. Selective DBS-induced deactivations in the SCAN, building on our recent @nature.com paper. nature.com/articles/s41... @ndosenbach.bsky.social

A recently discovered brain network that links cognition (thinking) and actions may have an important role in Parkinson’s disease and could improve its treatment, according to a study published in Nature: spklr.io/63320DMwOi #Neuroscience #Neuroskyence #Parkinsons 🧠 🧪

Game-changer for PD therapy! Our @Nature study shows targeting the SCAN network with non-invasive brain stimulation doubles efficacy—no surgery needed. #Therapy #BrainScience #HealthTech nature.com/articles/s41...

(4/4) Open datasets for PD and ET are still scarce, and we hope these resources will help advance research in the community.🧠🥳

(3/4) PIET includes 45 essential tremor patients, also with 30-minute scans. Download link: doi.org/10.57760/sci...

(2/4) PIPD includes 166 Parkinson’s disease patients and 60 healthy controls, each with ~30 minutes of rsfMRI data under strict motion control. Download link: doi.org/10.57760/sci...

In case this important point gets overlooked: along with our Nature paper, we’ve publicly released two large and scarce datasets—PIPD and PIET. IMHO, these are the best open Parkinson's and Tremor datasets available to date. See threads (1/4) 👇 nature.com/articles/s41...

Parkinson's disease affects over 10 million people worldwide. A new study led by WashU Medicine researchers is paving the way for more personalized, non-invasive treatment, tackling this neurological disorder at its root. @ndosenbach.bsky.social medicine.washu.edu/news/brain-n...

It’s time to rethink Parkinson’s disease. Our work reframes PD as a disorder of the somato-cognitive action network (SCAN), and shows that normalizing SCAN connectivity represents a shared mechanism across diverse effective therapies. rdcu.be/e2n4t @ndosenbach.bsky.social @gordonneuro.bsky.social

#Medsky🧪 #IDsky #Neurosky #publichealth @nature.com This study has redefined #ParkinsonsDisease (PD) as a disorder of the Somato-Cognitive Action Network (SCAN), a brain system that integrates whole-body movement, cognition, and internal physiological states www.nature.com/articles/s41...

Breakthrough @nature.com study showcases new non-invasive treatment for Parkinson’s Disease that targets the somato-cognitive action network (SCAN) with personalized neuromodulation, for superior outcomes. www.nature.com/articles/s41...

Scientists discover brain network that may cause Parkinson’s disease. Via @scientific_american #MedicalScience 💉💊🏥🩸😷 #neurology

Targeting the somato-cognitive action network (SCAN) rather than motor regions doubles efficacy of TMS treatments for Parkinson’s disease. Seems that various DBS targets for Parkinson’s are selectively connected to the SCAN rather than effector-specific motor regions.🧪 www.nature.com/articles/s41...

The highlight of my week was the publication of "Parkinson’s disease as a somato-cognitive action network disorder" in @nature.com. It's a great paper that shows how conceptual changes in fundamental neuroscience - the discovery of SCAN - can improve treatment 🧪 www.nature.com/articles/s41...

This is a nice animation illustrating the key points in the Parkinson's SCAN paper about which I posted previously.

Michael Okun's take on the SCAN Parkinson's story: www.linkedin.com/posts/michae...

Parkinson’s disease as a somato-cognitive action network disorder https://www.newsbeep.com/385135/ Participants In this study, we used 11 independent datasets comprising 863 total participants after quality control. These datasets…

Mapping the brain's core circuit: Chinese scientists identify key to Parkinson's treatment news.cgtn.com/news/2026-02...

"Brain stimulation treatments for Parkinson’s were more effective when doctors specifically targeted SCAN regions, Liu’s team also found. This experiment involved a noninvasive technique called transcranial magnetic simulation"

Scientists just discovered a key brain network affected by Parkinson’s disease. The finding could change how doctors understand symptoms and lead to better treatments. 🧠 bit.ly/4qdpLMf

Really cool attempt to link together multiple neuromodulation methods (DBS, TMS, TUS) to understand the neural basis of Parkinson's disease.

www.nature.com/articles/s41... the original research article ... no paywall

Non-invasive brain surface stimulation targeting personalized SCAN alleviated symptoms in patients with Parkinson’s disease. See the videos below.(www.nature.com/articles/s41...)

Happy to share a short but super cool video that gives a quick overview of our Nature paper on the somato-cognitive action of netwokr in Parkinson's disease www.nature.com/articles/s41...

An “extraordinary” brain network discovery shows that Parkinson’s disease may not be a movement disorder after all

I’m very excited about this new work describing the specific cortical-striatal circuits that are altered in Parkinson’s Disease and that should be targeted for optimal PD treatment. www.nature.com/articles/s41...