📣New from @awrgenes.bsky.social & co 📄The Indian Ocean slave trade and colonial expansion resulted in strong sex-biased admixture in South Africa www.cell.com/ajhg/fulltex...

New paper out! doi.org/10.1111/1755... Dental calculus allows us to study the oral microbiome of wild #mammals, but it's still underutilised! 🦷🦠 In this study, we recover oral #microbiome data from the dental calculus of 32 mammal species and share recommendations for future research. #museomics

Polygenic prediction of human complex traits using ancient DNA www.sciencedirect.com/science/arti...

🇵🇹Our paper on Portugal's genetic history is now published in Genome Biology. We present Portugal’s largest ancient genome collection, with deeper analyses than our pre-print, revealing migrations, admixture & continuity shorturl.at/TcErC @acadresearch.bsky.social @dnatimetravel.bsky.social

Today, our article "The entities enabling scientific fraud at scale are large, resilient, and growing rapidly" is finally published in PNAS. I hope that it proves to be a wake-up-call for the whole scientific community. reeserichardson.blog/2025/08/04/a...

#MetagenomicsMonday Analysis of aDNA from 1313 ancient human remains spanning 37k years revealed that the rise of infectious diseases coincided with animal domestication around 65k years ago, with disease spread intensifying during pastoralist migrations. www.nature.com/articles/s41...

Last week, the UNE Zoology Society organised a discussion panel about de-extinction which (inevitably) turned into a debate where I asked Andrew Pask about his attempt to "de-extinct" the Thylacine. Here is the recording of it if you want to watch the drama 🧪 echo360.net.au/media/8ccd63...

Genuinely thought some enterprising soul had been going around collecting samples of quicksand for aDNA analysis at first. I suppose all they’d find is the DNA of doomed explorers and tragic Victorian heiresses. www.biorxiv.org/content/10.1...

The genomic history of Iberian horses since the last Ice Age www.nature.com/articles/s41...

Results of our (extremely long-term) side project with @amygoldberg.bsky.social and @jgschraiber.bsky.social out now in G3: doi.org/10.1093/g3jo... We benchmarked methods for estimating ancestry proportions under mapping bias and present an adjusted GenotypeLikelihood to mitigate its impact (1/2)

Check out our recent review 'Power and Limitations of Inferring Genetic Ancestry'- what do we even mean by the term 'genetic ancestry' and what do commonly-used methods actually tell us?

So exciting to see this work being done by Claire Bowern, @dnatimetravel.bsky.social, Liusa Miceli, Raymond Tobler and @peteveth.bsky.social!

What a great academic and personal journey, indeed! Congrats @xavierrocarada.bsky.social!

Genetic Formation of Neolithic Hongshan People and Demic Expansion of Hongshan Culture Inferred From Ancient Human Genomes academic.oup.com/mbe/article/...

300,000-year-old wooden tools from Gantangqing, southwest China 300,000-year-old wooden tools from Gantangqing, southwest China | Science www.science.org/doi/10.1126/...

It started with a meeting between @mp-williams.bsky.social) and Robbi Davidson during the last @isbarchaeology.bsky.social conference (Tartu, 2023). I remember them sitting at the bar after lunch, engrossed in their discussion—that moment was even captured by the event photographer 🧵1/n

📣 Latest from the lab: Performance of deep-learning-based approaches to improve polygenic scores www.nature.com/articles/s41... Its thought deep learning will substantially improve PGS but the reality is MANY have tried but no/little gain has been seen so far. Here we report our negative results.

A 4-year postdoc position in population genomics is available in my group at the University of East Anglia, to work on a project sequencing a thousand fox genomes across rural and urban environments in the UK. vacancies.uea.ac.uk/vacancies/15...

Ancient DNA reveals a two-clanned matrilineal community in Neolithic China www.nature.com/articles/s41...

🚨 NEW preprint🚨 Our latest study @HPS MPI-GEA @elliescerri.bsky.social & @eegcam.bsky.social models #malaria risk over the past 74,000 years revealing its powerful role in shaping human habitat choice and dispersal since the late Pleistocene in sub-Saharan Africa 🦟🌍 www.biorxiv.org/content/10.1...

Cleaning the dead: Optimized decontamination enhances palaeoproteomic analyses of a Pleistocene hominin tooth from Khudji, Tajikistan www.sciencedirect.com/science/arti...

How global is archaeological science? www.sciencedirect.com/science/arti...

Out today in @pnas.org! www.pnas.org/doi/10.1073/...

Interested in measuring genetic load? We have a new paper out providing a modified version of GERP which is more user friendly in wildlife species and with scripts to automate making input files and pulling out derived alleles in your species #consgen #popgen star-protocols.cell.com/protocols/4202

Our latest paper is out now in Frontiers in Mammal Science: www.frontiersin.org/journals/mam... We characterized ZooMS peptide markers for three extinct Australian megafauna species 🦴🧪

🧬NEW: Our Dr Palesa Madupe & colleagues retrieved some of the oldest human genetic data from #Africa They identify 2million year-old protein remains from Paranthropus robustus to reveal its biological sex & genetic variability Read about this breakthrough in human evolution studies: bit.ly/3HiOgqP

It's not surprising, but still sad to see the estimates from this @nature.com paper showing the negative correlation between local plant diversity and the level of anthropogenic activity www.nature.com/articles/s41...

A Chromosome-level genome of the Nicobar pigeon, Caloenas nicobarica (the closest living relative of the extinct Dodo) academic.oup.com/jhered/advan... 🧬🖥️🧪 data: www.genomeark.org/genomeark-al...

The @upshot.nytimes.com has put together a vivid illustration of how the Trump administration has hollowed out American science. Gift link: nyti.ms/4kBTVql

Interested in investigating human history? Still a chance to join us in Uppsala as a junior or senior fellow! Closing date soon!

FutureHouse's goal has been to automate scientific discovery. Now we used our agents to make a genuine discovery – a potential new treatment for one kind of blindness (dAMD). We had multiple cycles of hypotheses, experiments, and data analysis – including identify the mechanism.

Excited to announce our paper on ancient Borrelia genomes is finally out! 🦠💀We document the evolutionary history of louse-borne relapsing fever, published today in @science.org‬ with @lucyvandorp.bsky.social and @pontus-skoglund.bsky.social #aDNA 🏺🧪🧬 Main findings and paper below: 🧵⬇️

⏰ - Less than 100 days until our first (virtual) HAAM-meeting during the @isbarchaeology.bsky.social symposium in Turin 🇮🇹 ✅ check out our website and feel free to submit your abstract for a flash talk at our meeting: tinyurl.com/haam-meeting... #aDNA #ISBA #conference #humanDNA #popgen

Who were the ancient Denisovans? Fossils reveal secrets about the mysterious humans. Clues are emerging about the ghostly clan that settled eastern Asia and left a genetic legacy in people today www.nature.com/articles/d41...

Discover our results of the largest ancient DNA study ever conducted on a single burial site: 400 skeletons from the Belgian city Sint-Truiden (8th–18th century). A unique glimpse into 1000 years of genetic history. (1/9) @kuleuvenuniversity.bsky.social

ConsensuSV-ONT: A modern method for accurate structural variant calling www.nature.com/articles/s41... 🧬🖥️🧪 Nextflow: github.com/SFGLab/Conse...

El estudio del genoma de 1537 individuos de 139 grupos étnicos permite narrar una historia de la migración humana del norte asiático hasta Sudamérica: From North Asia to South America: Tracing the longest human migration through genomic sequencing

Sedimentary ancient DNA from caves: Challenges and opportunities doi.org/10.1002/jqs.... , first publication from the PhD research of @siobhane13.bsky.social - congratulations!

"The mutton birds have become so full of plastic their bellies crunch & crackle with the sound of it." @SenatorSurfer told me about this a few weeks ago. If this is not another wake up call for our rampant destruction of this planet I don't know what is www.abc.net.au/news/2025-05...

Culturally appropriate resources and information about genetics and genomics created by the Australian National Centre for Indigenous Genomics (NCIG) ncig.anu.edu.au/resources

🏺 New preprint on the genetics of people buried in 5000-year-old Neolithic funerary monuments linked to Wartburg and Westen Funnelbeaker traditions in present-day Germany. Stresses close genetic relatedness between as well as within tombs, reproductive... www.researchsquare.com/article/rs-6...

Bonsai is out! Finally, we can visually explore high-dimensional data in a distortion-free way. Try it out! It works from scRNA-seq data (bonsai.unibas.ch/bonsai-scout...) up to football statistics (bonsai.unibas.ch/bonsai-scout...). 
Ever wondered why low-dimensional embeddings like t-SNE

My new book, “Sex Is a Spectrum: The Biological Limits of the Binary” publishes today from @princetonupress.bsky.social My goal in writing this book is to facilitate a better conversation. A short thread…

🎉 This paper has been a long time and a labour of love (and hardship) for multiple group members, but, finally: we MPRA'ed 25k introgressed variants (Denisovan and Neanderthal) segregating at allele frequencies > 0.15 in humans today to evaluate their potential to regulate gene expression.

A collaborative study initiated by the sovereign nation of Picuris Pueblo in New Mexico addresses gaps in traditional knowledge and furthers understanding of their population history and ancestry, according to a paper in Nature. go.nature.com/3YLNzfF 🏺 🧬 🧪

Check out the corresponding Cell paper. Amazing stuff. www.cell.com/cell/fulltex...

Bioinformatics seminar this Friday, May 2nd, with Jimmy Breen (Black Ochre Data Labs) — “Large Language Models for Investigating Genomic Variants and Regulatory Activity”. Details: adelaidebioinformatics.org/events/event... #bioinformatics #adelaide #BODL #events #seminar

I am very happy (and anxious) to share with you our most recent work in which we evaluated four of the most popular long-read assemblers, www.biorxiv.org/content/10.1... and tell you just a little bit about it in the following 🧵