#CRISPR base-editor #screens predict shared and drug-specific MEN1 #resistance mutations across five clinical menin inhibitors doi.org/10.1038/s414...

NEW CALL FOR PAPERS 📣 @natcomms.nature.com, @nature.com, @natcancer.nature.com, @natneuro.nature.com, Nature Progress Oncology, Nature Progress Brain Health and @commsbio.nature.com invite submissions on #CancerNeuroscience 👇 www.nature.com/collections/...

Intermediate #PRRX1 levels primes #cancer cell for high invasion and metastatic fitness, whereas extreme expression leads to cell cycle inhibition and #dormancy doi.org/10.1038/s414... @ruljcz.bsky.social @nietoangela.bsky.social

RIPK1-driven #necroptosis in both tumor and stromal compartments found to be essential for effective immunogenic cell death-based therapy and immune checkpoint @meierlabicr.bsky.social doi.org/10.1038/s414...

🚨 Exciting news! Our latest study is out in Nature Communications! We reveal how specific BRCA2 mutations can hijack transcriptional programs—beyond their role in DNA repair. 🔗 rdcu.be/eT1R9 #CancerResearch #BRCA2 #Genomics

Discovery of PI3K/AKT pathway as a relevant target to prevent therapy resistance in rhabdomyosarcoma. doi.org/10.1038/s414...

Missense mutations in the C-terminus region of USP28 discovered to disrupt 53BP1 interaction and p53 stabilization @meitinger.bsky.social doi.org/10.1038/s414...

Welcome to Communications Health! We are a new, open-access journal from @natureportfolio.nature.com. Now open for submissions in public and global health! www.nature.com/commshealth #PublicHealth #GlobalHealth #OpenAccess

Glad to share our latest perspective published on @natcomms.nature.com, trying to push #DTP research to a new frontier. Thanks to very helpful and constructive suggestions from the reviewers and editors!

Drug-tolerant persisters #DTP, a rare subpopulation of cancer cells, can survive therapy via reversible non-genetic mechanisms. @seansi.bsky.social lab provide their #perspective on the gaps and research paths still needed to bridge basic DTP research with the clinic. www.nature.com/articles/s41...

Report of a transgenic mouse model of renal tumorigenesis expressing the human SFPQ-TFE3 fusion, showing that the fusion regulates mTORC1 activity and induces lineage plasticity. doi.org/10.1038/s414...

We are hosting the webinar "Inflammatory cell death and anti-tumor immunity". Join us and our speakers Dmitri Krysko, Judy Lieberman, Lorenzo Galluzzi and @meierlabicr.bsky.social 📅 Tuesday 14th Oct 2025 ⏰ 16.00 PM (GMT+1) Register here: cassyni.com/events/QAERn...

A striking new study showing that #virus infection can awaken dormant #cancer cells 🦠🧪 "Increased risk of cancer-related death in COVID+ individuals was most pronounced in the months immediately following infection, mirroring the rapid proliferation of reawakened cancer cells observed in the mice"

Discovery of Netrin-1 promotion of sympathetic nerve remodeling in early pancreatic cancer lesions, having protective effect against their progression. @ibdm.bsky.social #CancerNeuroscience #PancreaticCancer, #NeuralRemodeling #PrecancerousLesions #CancerMicroenvironment doi.org/10.1038/s414...

Discovery that the increase of purinergic signaling factors promotes RBFOX1 degradation in cardiomyocytes, increasing the risk for developing chemotherapy-induced cardiotoxicity doi.org/10.1038/s414...

Hepatitis B virus promotes hepatocellular carcinoma formation only in response to environmental carcinogens, involving increased IL-33 signaling and regulatory T cells. doi.org/10.1038/s414...

Discovery that BMAL1 can form a heterodimer with HIF2α in clear cell renal cell carcinoma, contributing to tumor progression and response to HIF2α antagonist drugs. doi.org/10.1038/s414...

Use of an IL-12Fc fusion cytokine with abolished binding to the neonatal Fc receptor presents efficacy in local glioblastoma therapy while preventing toxicity doi.org/10.1038/s414...

Discovery of LKB1 regulation of JNK-dependent stress signaling pathway, and how it produces a shift in the apoptotic dependencies of KRAS-mutant tumors. doi.org/10.1038/s414...

New genomic & genetic insights into Mendel’s pea genes, including previously uncharacterised alleles 159 years after Mendel published his work, this is a real delight (especially for a geneticist) 🧪 @nature.com www.nature.com/articles/s41...

Discovery of the role in colon cancer cell proliferation of the secretion of Wnt5a by inflammatory cancer-associated fibroblasts induced by hypoxia. doi.org/10.1038/s414...

Coordinated expression of tumor antigens IFNα and IL-12 in liver and tumor-associated macrophages to rejuvenate tumor reactive T cells and eliminate liver metastases. doi.org/10.1038/s414...

“There is terrifically interesting stuff hiding in plain sight” New antibiotic that kills drug-resistant bacteria discovered in technician’s garden 🧪 @nature.com www.nature.com/articles/d41...

Targeting guanine nucleotide biosynthesis sensitizes leukemia stem cells of MLL-rearranged leukemia to menin inhibitors. #CancerResearch doi.org/10.1038/s414...

Looking forward to it! Please reach out if you want to discuss science and about publishing at @naturecomms.bsky.social 👋🏻🔬

Looking forward to attending the @helloeacr.bsky.social congress on "Persister Cells: from Bacteria to Cancer" in Lyon next month! Reach out to me if you want to discuss science and about publishing in @naturecomms.bsky.social 🔬👋🏻

NEW CALL FOR SUBMISSIONS 👇🏻✨

Discovery of how extracellular matrix organization influences tumor cell invasive and metastasis properties through induction of cytoskeletal and transcriptional memory doi.org/10.1038/s414... #CancerResearch

✨👇🏻

Loss of Brd7 promotes an immunosuppressive tumor microenvironment that drives breast cancer metastatic reawakening from dormancy in the lung www.nature.com/articles/s41... #CancerResearch

Curiosity of today 🥚🥚🥚

🎂Our 5-YEAR ANNIVERSARY Issue is now ONLINE! @NatureCancer Find it here: www.nature.com/natcancer/vo... Features: ⭐️Reviews and opinion pieces ⭐️Research articles on key developments in #cancerresearch and #oncology

Acogemos la jornada "Career opportunities in science" de #CNB_Postdoc Commission con los editores científicos Laura Sánchez @lausancburgos.bsky.social editora asociada en @naturecomms.bsky.social y David de Álamo cofundador de Fellowsherpa que comparten su trayectoria más allá del ámbito académico.

Hello Bluesky ✨ www.nature.com/articles/d41...