That we keep the screwworm at bay is a huge public health achievement. If we are having issues with screwworms it’s because we have cut the public health officials that maintain these efforts. www.youtube.com/watch?v=zxq6...

I would only ask MTG to consider what happens when he does this to democrats and others. What do those people face?

I don’t want to formulate words yet, but my friend Alice Wong, @sfdirewolf.bsky.social of the Disability Visibility Project, has passed. Here are the words she left behind: www.instagram.com/p/DREMDNBjnq...

This is the last in this thread, but I don't think most folks appreciate it. Expensive clothing today lasts longer and you end up spending a comparable amount or less in the long run.

Jeffrey Epstein sitting in Professor X's Cerebro helmet to locate every sex offender on the planet and broadcast to them a single global telepathic pulse that says "i,,m the .email pedaphole"

@hunterw.bsky.social I know you have the mention of a certain northeastern based publication muted, but you may want to unmute it today.

Larry Summers had an "insight" in an email to Epstein.

This is episode of Criminal is a good companion to Sam's article below. thisiscriminal.com/episode-339-...

Folks are dunking on Kim here but as @kenwhite.bsky.social points out she has a good heart and is trying to do actual good. I'd point out that the ability integrate new knowledge to reevaluate her beliefs at 45 is something many folks are incapable of.

American politics makes a lot more sense when you realize that the GOP is afraid of pissing off the GOP base, and the Dems are afraid of pissing off the GOP base, but neither party is afraid of pissing off the Dem base.

pre-writing a devastating obituary for your enemy is god-tier hating of a kind you don’t often see anymore. renaissance haterism. beautiful stuff.

The world would be immensely better if more religions and their believers had even a tenth of the dedication the Sikhs do to doing good for people with no gatekeeping or expectations of anything other than "you are a fellow human in need and we can help you"

Let me introduce you to `replace_when()` in tidyup #7 🙂 github.com/tidyverse/ti...

I helped make a film, out this week, called “Rovina’s Choice,” about the deaths this man without conscience or accountability has caused — already 600,000, ⅔ of them children.

This is nice.

I got a letter from the government the other day I opened and read it it said you get free electricity

This is the way.

I knew it would take less than a day for a tiktok dj to make something.

Zohran's success will hinge equally on what he is ABLE to do and how effectively he messages to voters when the federal govt of wealthy interests / police, etc in NYC deliberately sabotage things. we've seen this shit in oregon with elites lining up to torpedo progressive measures

There's a character in Monsoon Wedding who is an unforgivable abusive predator, so Cuomo could have quoted Mamdani's parent's work, too.

I cannot stress that the work that people have been doing for years in the southeast is paying off and needs to be celebrated.

So @giadapistilli.com isn't blocked by any lists I subscribe to. And also not blocked by me. So I can see her profile. I've never read anything by her. But she's only posted 283 times. I think any exposure/engagement issue she may has more to do with her than being on some random block lists.

we ended up where we are now for a number of reasons, but one was that Dick Cheney realized he could go on camera, lie about saying things he’d previously said on camera, and TV interviewers would just sputter

On the other site, an 18-year-old Zohran canvasser described the legendary Wallace Shawn as "the actor who plays Dr. Sturgis on Young Sheldon" which is honestly adorable

youtu.be/w1fzg9GC5UU?... I really enjoyed this overview of the history and geography of Amsterdam.

These yahoos don't understand that biotech has a completely different set of incentive structures to fight frivolous litigation, they aren't broke newspapers.

saints walk amongst us

This year Demis Hassabis predicted AI could cure all disease in a decade. But other scientists like Claus Wilke & Derek Lowe say biology is far more complex, or progress will be limited by clinical trials & economics. In a new 4hr podcast episode of *Hard Drugs*, we answer: Will AI solve medicine?

New from me: Elite law firms, multiple media outlets, the D.C. attorney general, and a group of parents accused a teacher of molesting 15 kids. They were wrong. This piece is two-and-a-half years in the making. And as you'll see, it took some incredible turns, even as I was reporting it.

Carolyn June Dennis, 1944-2025 “There is no perfection on the physical plane.” This was a saying that my mother, who died October 21, 2025 at 81 after a long period with Alzheimer’s, used to repeat often, especially when confronted with some daily frustration or tragedy of life. Cont'd. 🧵

Where are all the debate bros, free speech absolutists, win the battle of ideas with more speech people?

Apparently some folks are playing real dumb about skull symbols so let’s play a little game I like to call “Nazi skull or not a Nazi skull” First up, the Jolly Roger. This is a pirate skull, not a Nazi skull. It means you might get robbed, but prolly not genocided. With me so far? 1/x

Schiff voted to confirm one of Trump’s judges roughly an hour before his account posted this.

This, from an author who doesn't have a health science background, explains it so beautifully that the gen population can understand it if they have a doubt. This IS science communication, and is superior to a fancy chart that wins a competition but can't be interpreted by the gen population.

The linked post in this skeet sums up how I use LLMs in practice and this figure is a good graphical example.

I often get attacked for posting about the potential harms caused by dietary supplements, and I do not care. It’s important for the public to have accurate information. Supplements are made by companies just like Big Pharma, except without intensive FDA oversight. They can cause harm.

This month, I'm excited to introduce two new estimation methods in nlmixr2: Laplace (laplace) and adaptive Gaussian Quadrature (agq). blog.nlmixr2.org/blog/2025-10...

Monty Python understood p-hacking

I don’t speak much Dutch at all, but I am having serious bike acquisition urges after watching this video for a senior citizen bike 4wielfiets.nl?fbclid=IwY2x...

Yep, we've seen the massive #NoKings rallies, with tens of thousands gathered in big cities across the country. But y'all look at this small protest of 11 people in the small, small town of Kosciusko, Mississppi. That's democracy, too. www.mississippifreepress.org/no-kings-pro...

I was reading a thread on the economics of being in a mid-tier rock band, and saw this comment. Hadn’t really thought about it!

Putting a Democrat with a Nazi tattoo in the Senate normalizes Naziism in our federal politics for a long ass time. All these recent stories about secret Nazi group chats? Anytime that happens going forward will be met with "But Platner." It's not a purity test. Think through the consequences.

I come back a lot to the idea that "no politics at the dinner table" was harmful and let this kind of shitty ideology fester undiscussed

The entire "free speech on campus" moral panic was manufactured to blackmail us into making space in intellectual life for bigots and charlatans who couldn't get there on their own merits. Its a DEI scheme for fascism. Congratulations to everyone who took it at face value.

Are we doing "The ACA Sucks" Discourse again? I'm going to guess most people hating on it from the left have never received a hospital bill the size of book; I put the apple there for scale. That's the $1.3 million bill my kid incurred in his first ~94 days. Why does that make me respect the ACA?

“Supremacy is an all-consuming logic on the MAGA right today. Christian supremacy, white supremacy, male supremacy, almost every corner of MAGA is marked by one or some combination of supremacist logic and a desire to subjugate some other group.” www.liberalcurrents.com/sex-is-gay-r...

Portland ICE facility now.

@dereklowe.bsky.social This is right up your alley if you haven't seen it already.