Check out this important advance in mitochondrial 🧬 lineage tracing by @gaoteng.bsky.social and @wengchen.bsky.social from our group, in collaboration with @jswlab.bsky.social 👇👇

Mitochondrial lineage tracing brought exciting new capabilities to single-cell genomics. However, a core problem remains: unlike classical lineage recorders, mtDNA mutations can drift and disappear as cells divide, preventing us from precisely decoding lineage history.

@biorxivpreprint.bsky.social Modeling mitochondrial inheritance enables high-precision single-cell lineage tracing in humans www.biorxiv.org/content/10.6... @bloodgenes.bsky.social @jswlab.bsky.social @bostonchildrens.bsky.social @hhmi-science.bsky.social @broadinstitute.org