The Freeze lab and an international team of collaborators discovered a new rare genetic disease that interferes with brain development. They published findings in @hggadvances.bsky.social that identify the faulty mutated gene and show how it interferes with normal cellular function. bit.ly/4vul3h3

Nearly 40% of U.S. adults have metabolic syndrome, a condition that can lead to liver damage and fibrosis. A new study from Sanford Burnham Prebys highlights LARP6, an RNA-binding protein that helps drive fibrosis and may be a promising therapeutic target. sbpdiscovery.org/press/living...

Thank you to The San Diego Union-Tribune for helping share the story of Sanford Burnham Prebys as we mark 50 years of discovery and impact. We’re grateful for the spotlight on the people, science and community that have shaped our Institute since 1976. www.sandiegouniontribune.com/2026/02/27/a...

An international team including the Kaufman lab published in Nature.com showing that liver cell stress can both drive cancer and make tumors less resistant to immunotherapy. The findings may help physicians identify which patients are most likely to benefit from existing treatments.

Today, on International Day of #WomenAndGirlsInScience, we gathered for the latest Women in Science Lecture Series. Thank you for the thoughtful and engaging conversation Cheryl Anderson, PhD, MPH, MS and Angela Liou, MD. Grateful to everyone who joined us. #InternationalDayOfWomenAndGirlsInScience

Sanford Burnham Prebys scientists published in @cp-cellreports.bsky.social showcasing a new approach for measuring the activity of enzymes linked to cell death and a more complicated picture where protein activation cannot always be presumed by protein production. sbpdiscovery.org/press/metall...

Join us on February 11 for the next event in the Women in Science Lecture Series at Sanford Burnham Prebys, featuring a lecture and fireside chat that highlight the groundbreaking work and perspectives of women leaders in biomedical science. Must RSVP to attend: lnkd.in/gzkXQRrm

Advancing Together: 50 Years of Sanford Burnham Prebys - For 50 years, bold ideas, dedicated scientists, and a shared commitment to discovery have shaped who we are today. Join us as we celebrate this milestone year and look ahead to the next 50. youtu.be/Q4hNMzBq7N0?...

In this episode of the Epigenetics Podcast, we talked with Will Wang from @sbpdiscovery.bsky.social about his work on muscle stem cell repair, regeneration, and aging, exploring spatial-omics and machine learning. #podcast #epigenetics Listen here: activemotif.com/podcasts-wil...

New research from Sanju Sinha, PhD, introduces DeepTarget, a tool that predicts both primary and secondary targets of cancer drugs. It could help repurpose existing medicines for more patients. sbpdiscovery.org/press/comput...

Meet Rouven Arnold, PhD, a postdoc in Peter Adams’ lab at Sanford Burnham Prebys. He studies how aging changes our cells—with the goal of preventing diseases like heart disease, cancer, and dementia. Learn what drives his work and his path into science. ➡️ https://bit.ly/47PtecX

Scientists at Sanford Burnham Prebys, the University of Minnesota and Duke University report in Nature that “biased modulators” can target GPCRs more precisely—expanding potential drug targets and reducing side effects. www.nature.com/articles/s41...

“Once we find the players that drive disease, we can find drugs to help,” says Sanjeev Ranade, PhD. New study reveals a key protein linked to heart defects in Down syndrome. 🧬❤️ sbpdiscovery.org/press/huntin...

🧬 Biomedical Sciences PhD Applications Now Open! Do you want to explore the science behind human health and disease? Our program is looking for curious and driven researchers ready to tackle the most pressing questions in biology and medicine. sbpdiscovery.org/education/gr...

We’re pleased to announce that Paul Boutros, PhD, MBA, has been named the new director of the National Cancer Institute (NCI) designated cancer center at Sanford Burnham Prebys Medical Discovery Institute. Read all about it! sbpdiscovery.org/press/paul-b...

👏 Congratulations to Xueqin Sherine Sun, PhD, on receiving a $600,000 grant from the V Foundation for Cancer Research to study glioblastoma, one of the most common and deadly brain cancers. sbpdiscovery.org/xueqin-sun-a...

What connects survival, science + diabetes care? Adam Heller, PhD. At 92, this Holocaust survivor, scientist + engineer shares how his innovations changed how millions manage diabetes. 🎙️Hear his remarkable story in Episode 5 of the podcast. 👀On YouTube: youtu.be/TEhPlF29yl4?...

Today, 62 National Cancer Institute (NCI)–Designated Cancer Centers issued a joint statement underscoring the importance of HPV vaccination. #HPVvaccine #HPVvax #EndHPVCancers

🔬 New research from the @anideshpande.bsky.social Deshpande lab at Sanford Burnham Prebys. The study demonstrates how public genomic screening data can be used to uncover a new genetic vulnerability in synovial sarcoma. 👏 Shout out to Rema Iyer, PhD lead author of the manuscript.

For decades, scientists thought MYOD was just a muscle-builder. But new research from Sanford Burnham Prebys shows this gene has a Jekyll-and-Hyde side—able to switch from activating muscle genes to silencing them. sbpdiscovery.org/press/muscle...

Proud to host six high school interns from the Preuss School for a hands-on research experience at Sanford Burnham Prebys. 👏 Thanks to Peggy & Peter Preuss and Debby & Wain Fishburn for making it possible! sbpdiscovery.org/preuss-schoo...

New research from the Marth Lab: Most blood glycoproteins are easy to spot—but finding the rare ones is like searching for Waldo across every book. 🧠🧬 🔗 Read more: sbpdiscovery.org/press/signal... #Biomedicine #SanfordBurnhamPrebys #NatureCommunications #Science

Meet Meena Sudhakaran, PhD, a postdoc in the Kersten Lab at Sanford Burnham Prebys. She’s advancing cancer immunology to improve immunotherapy for breast cancer. Read more about her journey into science: sbpdiscovery.org/q-and-a-with... #CancerResearch #PostdocLife

#ArticleinPress: Peroxisome Proliferator-activated Receptor Agonist IVA337 Alleviates Inflammation and Fibrosis in MASH by Restoring Lipid Homeostasis. @ucsandiego.bsky.social and @sbpdiscovery.bsky.social. #OpenAccess text: ajp.amjpathol.org/article/S000...

A promising advance for pancreatic cancer published Cancer Cell: Blocking macropinocytosis reduces fibrosis around pancreatic tumors, improving immune cell access & boosting response to chemo & immunotherapy in mice. sbpdiscovery.org/press/reshap... @cosimocommisso.bsky.social @yijuan.bsky.social

Big congrats to grad students Aashna Lamba & Ashley Neil at @SBPdiscovery—named 2025 CIRM Predoctoral Fellows! 🌟 Lamba’s research could help hearts heal after injury ❤️ Neil is exploring brain inflammation in Alzheimer’s 🧠 #SanfordBurnhamPrebys #RegenerativeMedicine #CIRM #STEM

📣 Welcome Michael Karin, Ph.D., to Sanford Burnham Prebys! He joins as director of the new Center for Metabolic and Liver Diseases and will continue his pioneering work on chronic inflammation and cancer. sbpdiscovery.org/press/leadin...

What if the key to major medical breakthroughs is already sitting in clinical databases—just waiting to be unlocked? Sanford Burnham Prebys CEO David Brenner shares why tapping into electronic health records could transform research and care. Read more: www.sandiegouniontribune.com/2025/06/23/o...

Cheers to the newest grads of the Sanford Burnham Prebys Graduate School of Biomedical Sciences! 🎓🔬♥️ Their hard work, perseverance, and curiosity reflect the spirit of our graduate program's motto: “Knowledge is the power to heal.” Congrats to these rising scientists. More: https://bit.ly/3HFmyEB

🧠 Could HIV drugs help lower #Alzheimer’s risk? New research from Sanford Burnham Prebys, led by Jerold Chun, MD, PhD, found that patients taking #HIV drugs blocking #reversetranscriptase had fewer cases of Alzheimer’s—pointing to a potential drug target. More: https://bit.ly/4kuxvHU

Centenarians in Cilento are thriving thanks to a Mediterranean way of life. The CIAO Study 🌿 reveals they’re biologically younger, with resilient immune systems & strong social ties—offering real clues to how we can all age better. More: https://bit.ly/45HjqCf #CIAOstudy #longevity #healthyaging

Evan Snyder, MD, PhD, professor in the Center for Neurologic Diseases at Sanford Burnham Prebys, was named a Fellow of the Child Neurology Society for his clinical expertise and pioneering research in #pediatricneuroscience and #stemcellbiology. 🧠 Learn more: 🔗 https://bit.ly/4jATHio

From cancer and aging to immunotherapy and AI, these new PhDs are already making an impact—and they’re just getting started. 👏 Learn more about how we’re training tomorrow’s scientists: vist.ly/3n5mjza #SBPgrad #PhDlife #FutureOfScience #BiomedicalResearch #CancerResearch #Immunotherapy

The Prebys Foundation has announced a $7M emergency funding package for seven top-tier biomedical research institutions in San Diego, a global hub of scientific innovation, including Sanford Burnham Prebys. Learn more: 🔗 https://bit.ly/4kiJ84H

🎙️ Catch Ani Deshpande, PhD, in episode 151 of the @epigeneticspod.bsky.social‬‬ where he discusses his work on epigenetic regulation in #AML, and the use of #CRISPR and high throughput screens for drug discovery. ▶️ YouTube: vist.ly/3n5jemi ᯤ Spotify: vist.ly/3n5jemj

Check out our Q&A with scientists and podcasters Ani Deshpande & Pam Itkin-Ansari! Their podcast 𝑇ℎ𝑒 𝐷𝑖𝑠𝑐𝑜𝑣𝑒𝑟𝑦 𝐷𝑖𝑎𝑙𝑜𝑔𝑢𝑒𝑠 is blowing minds—venom, insulin, and Ozempic all in one. 🎧💉 Listen: https://bit.ly/3Fmu4nl

Cutting NIH funding means fewer cures, fewer trials, and slower progress. San Diego researchers are speaking out. 🧬 Dr. Kurt Marek of Sanford Burnham Prebys joined the call to protect science. 🔗 www.10news.com/news/local-n... #FundScience #NIH

Doctoral-degree candidates visited Sanford Burnham Prebys for the Rising Stars Symposium—great opportunity to explore postdoc life at the Institute—featuring research talks, networking and a keynote from Mark Mercola, PhD, of @StanfordMedicine . Read more: vist.ly/3n4bs6w

Kelly Kersten, PhD, has received a grant from the Melanoma Research Alliance @melanomaresearch.bsky.social to study how to restore the function of exhausted #immunecells in #melanoma tumors. The award is part of MRA’s $9.3M research funding commitment for 2025. Learn more: 🔗 vist.ly/3n3ney9

📢 Calling all advanced graduate students and prospective postdocs! Thinking about your next move after grad school? We're hosting a Postdoc Virtual Open House 🖥️ on May 19, 2025, from 10:00 a.m. to 3:00 p.m. PT. Join us to learn more: 🔗 vist.ly/3n36wva

Researchers from the CIAO (Cilento Initiative on Aging Outcomes) study are gathering in Cilento, Italy📍 to mark 10 years of exploring what drives healthy aging and longevity. When your subjects live past 100, a decade of science is just the beginning. Read more: 🔗 vist.ly/3n3jq33

🚨 Just dropped on Radiolab! Hudson Freeze, PhD, tells the wild true story of how a search for life in boiling water changed biology—and saved millions. 🎧 Listen here: vist.ly/3m2rymx #Radiolab #SanfordBurnhamPrebys #ScienceMatters

Sanford Burnham Prebys hosted 𝘈 𝘊𝘰𝘯𝘷𝘦𝘳𝘴𝘢𝘵𝘪𝘰𝘯 𝘈𝘣𝘰𝘶𝘵: 𝘈𝘨𝘪𝘯𝘨 𝘢𝘯𝘥 𝘈𝘭𝘻𝘩𝘦𝘪𝘮𝘦𝘳’𝘴, featuring leading scientists and author Muffy Walker. The event highlighted advances in research and care. Watch the full program here: vist.ly/3m2n2ns

NIH cuts and terminated grants undermine research on infectious diseases, vaccines, public health and more. David A. Brenner, PhD, president and CEO of Sanford Burnham Prebys provides his perspective: less science equals fewer breakthroughs resulting in weaker health outcomes: https://bit.ly/4jnAUaT

Cosimo Commisso, PhD, was featured on the @ProjectPurple Podcast, which includes conversations with pancreatic cancer survivors, physicians and researchers. Project Purple is a nonprofit focused on #pancreaticcancer research and support for patients and their families. More: https://bit.ly/3Y823pH

Our final March #TopRead is from Dr. Carl Ware, @sbpdiscovery.bsky.social, who described the first method to directly quantify the HVEM-BTLA cis-complex. Find it in The JI: ow.ly/nElT50VAjzY.

I joined the Project Purple Podcast to talk about how pancreatic cancer cells survive, how we can target them, and why research funding matters more than ever. Listen here: podcasts.apple.com/us/podcast/e...

#REVIEW 🚨 Brooke Emerling & Co @sbpdiscovery.bsky.social @bemerling.bsky.social#REVIEWsummarize the roles of phosphatidylinositol 4-kinases #PI4Ks and phosphatidylinositol phosphate kinases #PIPKs in cancer. 📖 ⬇️

This week, we observe #GraduateStudentAppreciationWeek. Our graduate students are integral to the Institute’s mission—to energize, accelerate and reimagine translational research. Join us in expressing gratitude for their outstanding contributions: https://bit.ly/42pzTaU 🧪🔬📚 🧫

The Queer Scientists and Allies Symposium was held at Sanford Burnham Prebys on April 4, 2025, connecting LGBTQIA+ researchers and showcasing their work. Local organizations also supported the event. Read more: 🔗 vist.ly/3mzhra7 🧑🏻‍🔬👨🏽‍🔬👩🏾‍🔬