Machine Learning Predicts Adequacy of Rapid On-site Evaluation in Fine Needle Aspirations in Lung Cancer Cytology. Authors from @tum.de, @helmholtzmunich.bsky.social #OpenAccess text: https://loom.ly/mppJrlU

Read the June issue of @ajpathology.bsky.social online! Full issue: https://ajp.amjpathol.org/issue/S0002-9440(25)X0008-0 On the cover: Safranin-O growth plate staining in D167N mice

Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00030-1/fulltext

Epidermal Growth Factor Receptor/KIT-Linked Proliferative Bias in Normal Breast Lobules from Matched Non-Hispanic Black and White Women Is Rapidly Reversible by Receptor Tyrosine Kinase Inhibition. #OpenAccess text: https://loom.ly/M5CcD0E

Pseudogene-Derived Long Noncoding RNAs GSTM3P1/Gstm2-ps1 Exacerbate Sepsis-Associated Acute Kidney Injury by Suppressing Their Parent Gene Translation. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00029-5/fulltext

We still have lots of great science today at #Pathobiology2026! #PathobiologyResearch #DiseaseMechanisms #ASIP2026

Non–Cell-Autonomous Mechanisms and Systemic Interactions in Spinal Muscular Atrophy. Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00036-2/fulltext

@asipath.bsky.social 2026 Outstanding Investigator Award lecture Review: Central Role of MITF/TFE Family Transcription Factors in Diverse Clear and Granular Cell Tumors. Read for free: https://ajp.amjpathol.org/article/S0002-9440(26)00035-0/fulltext

Long Noncoding RNA Isoform Specificity and Chemical Modification on tRNA-Derived Fragments Leading to Divergent. Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00057-X/fulltext

#Pathobiology2026 Day 1 is underway! Come to the main office/poster all and snap a pic in front of the banner.

A new publication from the Hannafon Lab "Spatially Resolved Obesity-Driven Molecular Changes in Early Breast Cancer" in the @ajpathology.bsky.social www.sciencedirect.com/science/arti...

#LegacyContent: From Ulcerative Colitis to Metastatic Colorectal Cancer: The Neutrophil Contribution. Full text: ajp.amjpathol.org/article/S000...

#ArticleinPress: Growth Differentiation Factor 11 Promotes Corneal Endothelial Injury Repair by Activating the SRY-Box Transcription Factor 9–β-Catenin Signaling Pathway. Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00073-8/fulltext

#ArticleinPress: Elevated CD45+CD11c+CX3CR1+ Cells in Optic Nerves and Their Relation to Optic Nerve Function in an Experimental Autoimmune Encephalomyelitis Model #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00071-4/fulltext

#ArticleinPress: Gpat3 Knockout Attenuates Adipose Loss and Steatohepatitis in Agpat2-Deficient Mice Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00069-6/fulltext

#ArticleinPress: SYT8 Drives Colorectal Cancer Progression and Immune Evasion via the SETD1A-H3K4me3 Axis. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00070-2/fulltext

#ArticleinPress: Molecular Switching from Morule to Squamous Metaplasia via p40 and the EBP50/S100A4/Myosin 9 Axis in Endometrial Carcinoma #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00072-6/fulltext

#ArticleinPress: Small Ubiquitin-Like Modifier 3 Attenuates Lung Ischemia-Reperfusion Injury Progression by Inhibiting Endoplasmic Reticulum Stress through Heat Shock Protein 70 #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00068-4/fulltext

#ArticleinPress: R-Propranolol Promotes the Adipogenesis and Subsequent Apoptosis of Hemangioma Stem Cells through the Protein Kinase RNA-Like Endoplasmic Reticulum Kinase Signaling Pathway. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00065-9/fulltext

Leukocytic Dopamine D2 Receptors as Biomarkers for Brain Dopamine Levels in Parkinson Disease. From @asipath.bsky.social member Scott Steffensen. Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00028-3/fulltext

#ArticleinPress: The Pathogenic ADAMTSL2 D167N Variant Causes Geleophysic Dysplasia–Like Connective Tissue Changes in Mice. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00064-7/fulltext

#ArticleinPress: Notch1-Gli1 Axis Reprograms Macrophage Polarization and Promotes Hepatic Inflammation and Fibrosis in Metabolic Dysfunction–Associated Steatohepatitis. Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00063-5/fulltext

#ArticleinPress: Machine Learning Predicts Adequacy of Rapid On-site Evaluation in Fine Needle Aspirations in Lung Cancer Cytology. Authors from @tum.de, @helmholtzmunich.bsky.social #OpenAccess text: https://loom.ly/mppJrlU

Pseudogene-Derived Long Noncoding RNAs GSTM3P1/Gstm2-ps1 Exacerbate Sepsis-Associated Acute Kidney Injury by Suppressing Their Parent Gene Translation #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00029-5/fulltext

#ArticleinPress: Epigenetic and Transcriptional Regulatory Networks Underlying #Psoriasis Pathogenesis. Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00066-0/fulltext

The May issue of @ajpathology.bsky.social is now live! Full issue: https://ajp.amjpathol.org/issue/S0002-9440(25)X0007-9 On the cover: Meflin-high region in human triple-negative breast cancer.

#ArticleinPress: Deep Learning–Enhanced Biomarker Interpretation on Cytology Cell Blocks: Foundations and Emerging Opportunities in Spatial Pathobiology #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00056-8/fulltext

#ArticleinPress: Spatial Transcriptomics Profiling of Small Intestine Adenocarcinoma and Adenoma in Humans and a Murine Model with KRASG12D and Loss of CDKN2a-p16. @columbiauniversity.bsky.social Full text: https://loom.ly/ykK7XRQ

Send your #mechanistic discoveries to @ajpathology.bsky.social for publication! Submission is free and can be done online: https://www.editorialmanager.com/ajpa/default2.aspx

#LegacyContent: Histopathologic Marks of Tongue in a Mouse Model of Oculopharyngeal Muscular Dystrophy Suggest Biomechanical Defects. Free #OpenAccess text: ajp.amjpathol.org/article/S000...

#ArticleinPress: Redefining Pathobiology with Spatial Multi-Omics at the Intersection of Biology, Computation, and Histopathological Assessment. Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00032-5/fulltext

Single-Cell Triomics Analysis of Tumor Cells Infiltrating Patient-Derived Breast Cancer Scaffolds. Authors from @missionbio.bsky.social #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00008-8/fulltext

#ArticleinPress: Applications of Spatial Transcriptomics in Ischemic Stroke Research. Authors from @czechacademy.bsky.social. Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00033-7/fulltext

Dr. Richard Mitchell, Prof. of Pathology at @brighamandwomens.bsky.social and @harvardmed.bsky.social and Associate Dir. of Curriculum at Harvard-MIT HST, to Receive Inaugural ASIP Excellence in Mentoring Award! bit.ly/4eDKEy6

Deciphering the Cellular and Metabolic Landscape of Lymph Node Metastasis in Breast Cancer Using Single-Cell and Spatial Multi-Omics Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00007-6/fulltext

#LegacyContent: Beyond Redox Regulation: Novel Roles of TXNIP in the Pathogenesis and Therapeutic Targeting of Kidney Disease. Full text: ajp.amjpathol.org/article/S000...

Deficiency of Mesencephalic Astrocyte–Derived Neurotrophic Factor Aggravates Acute Pancreatitis in Mice Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00003-9/fulltext

Colitogenic Environment Suppresses Notch/Mechanistic Target of Rapamycin–Mediated Epithelial Proliferation to Promote Goblet Cell Differentiation in the Colon Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00005-2/fulltext

Rora Regulates Hematopoietic Stem Cell Phenotypes and Progression of Chronic Myelogenous Leukemia Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00004-0/fulltext

#LegacyContent: Tissue Inhibitor of Metalloproteinase-2 Promotes Wound Healing by Suppressing Matrix Metalloproteinases and Inflammatory Cytokines in Corneal Epithelial Cells. Authors from @harvardmed.bsky.social Free in the #OpenArchive: ajp.amjpathol.org/article/S000...

Check out this new study from Mass General Brigham researchers in @ajpathology.bsky.social!

ADH1C Down-Regulation Is a Key Hypoxia Response in Colon Epithelium #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00002-7/fulltext

Keratocyte Depletion by Genetic Manipulation Re-creates Corneal Ectasia in a Mouse Model Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00465-1/fulltext

#ArticleinPress: Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00030-1/fulltext

Peroxisome Proliferator-Activated Receptor α Deficiency Induces Vascular Pathologies through Endothelial Senescence in Diabetic Retinopathy #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00466-3/fulltext

Neonatal Thymic Dynamics Influence Autoimmune Pathology by Shaping the Suppressive Potential of Regulatory T Cells #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00467-5/fulltext

#ArticleinPress: Pseudogene-Derived Long Noncoding RNAs GSTM3P1/Gstm2-ps1 Exacerbate Sepsis-Associated Acute Kidney Injury by Suppressing Their Parent Gene Translation #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(26)00029-5/fulltext

#LegacyContent: Characterization and Role of Glucagon-Like Peptide 1 Receptor in the Lacrimal Gland: Novel Insights into Diabetic Dry Eye Pathogenesis. Free in the #OpenArchive: ajp.amjpathol.org/article/S000...

#ArticleinPress: Leukocytic Dopamine D2 Receptors as Biomarkers for Brain Dopamine Levels in Parkinson Disease. From @asipath.bsky.social member Scott Steffensen. Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00028-3/fulltext

#ArticleinPress: Redefining Pathobiology with Spatial Multi-Omics at the Intersection of Biology, Computation, and Histopathological Assessment Full text: https://ajp.amjpathol.org/article/S0002-9440(26)00032-5/fulltext