#ArticleinPress: Prostaglandin E2 Signaling Triggers CD31-Independent Transendothelial Migration in Vitro and in Vivo. From authors at @nufeinbergmed.bsky.social and @uhn.ca Full text: https://loom.ly/pItFdx0

Lipid Droplet Dynamics in Alcoholic Steatohepatitis. Authors from @unmc.bsky.social #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00299-8/fulltext

#CallforPapers! Ocular Pathobiology researchers- @ajpathology.bsky.social seeks your original research into the mechanisms of disease for an upcoming special issue. Submit online for free: https://loom.ly/GTKfx4o#CallforPapers Deadline extended to January 31, 2026

An Update on Animal Models of Alcohol-Associated Liver Disease. From @asipath.bsky.social member Wen-Wing Ding and colleagues at UKMC. Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00032-X/fulltext

Read the introductory Editorial for this month's special Alcohol Induced Organ Theme issue! Alcohol Provokes Multi-Organ Injury through Multi-Mechanisms Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00402-X/fulltext

Happy New Year from @ajpathology.bsky.social! Thank you to everyone that worked on the Journal through 2025, we couldn't do it without the authors, reviewers, editors, and staff that help put our publication out every month.

Decreased Glycolysis due to LDHA m6A methylation in Endometrium of endometriosis impairs its decidualization and contributes to related infertility Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00359-1/fulltext

The Gut Microbiome as a Possible Mediator in Autoimmunity and Cardiovascular Disease: Shared Pathways and Therapeutic Implications. Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00358-X/fulltext

#ArticleinPress: Improving Colorectal Cancer Screening and Risk Assessment through Predictive Modeling on Medical Images and Records. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00380-3/fulltext

Interplay between Leptin and Stearoyl-CoA Desaturase 1 in Estrogen Receptor-positive Breast Cancer Cells #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00336-0/fulltext

Cross-Modality Learning for Predicting IHC Biomarkers from H&E-Stained Whole-Slide Images #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00341-4/fulltext

Stromal SRD5A2 promotes prostate growth through WNT5A-LEF1-IGF1 signaling in benign prostatic hyperplasia. Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00338-4/fulltext

SCG2 transcriptionally activated by SP1 promotes nasal epithelial cell proliferation and epithelial mesenchymal transition Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00333-5/fulltext

Growth differentiation factor 11 attenuates photoaging through ferroptosis pathway in SZ95 sebocytes. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00332-3/fulltext

The role of extracellular vesicle-derived miRNA in the atherosclerotic burden. Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00330-X/fulltext

AJP (@ajpathology.bsky.social) is the flagship publication of ASIP, and this year marks 100 years of publishing! We encourage submission of research that address mechanisms of pathogenesis or provide a foundation for future mechanistic studies #GenomicMedicine

From Theory to Practice: A Comprehensive Review of Pseudomyxoma Peritonei Research and Its Implications for Future Treatment. Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00329-3/fulltext

#AJPCentennial A Seminal Work That Defined the Pathology of Frontotemporal Dementias and the Concept of TDP-43 Proteinopathies Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00357-8/fulltext

Laminin Receptors in Peripheral Tissues --- Functions Revealed by Analysis of Knockout Mice. From @asipath.bsky.social member Yao Yao at @usf.edu Full text: https://loom.ly/kxK1Ues

#AJPCentennial @ajpathology.bsky.social and the @asipath.bsky.social: Forging the Next Century of Insights into Mechanisms of Disease Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00373-6/fulltext

The December issue of @ajpathology.bsky.social is live online! Full issue: https://ajp.amjpathol.org/issue/S0002-9440(24)X0013-9 On the cover: NLRP3 and in Hypokalemic Nephropathy and Sjogren Syndrome

Time is almost up in the #CallforPapers related to Spatial Pathobiology! Send in your original research for consideration in this theme issue by the end of the weekend! https://www.editorialmanager.com/ajpa/default2.aspx

The Proteostasis Network in Proteinopathies: Mechanisms and Interconnections. Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00300-1/fulltext

Uncovering the Unique Roles of Cathepsins B and L in Purkinje cells using Nervous System-specific CTSB and CTSL Double-deficient Mice. Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00144-0/fulltext

Novel Kinesin Family 1A Variants Linked to Atypical Parkinsonism Elicit Altered Neuronal TDP-43 Interactions and Dendritic Atrophy. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00204-4/fulltext

AJP (@ajpathology.bsky.social) is the flagship publication of ASIP, and this year marks 100 years of publishing! We encourage submission of research that address mechanisms of pathogenesis or provide a foundation for future mechanistic studies #OcularPathobiology

P-Glycoprotein Drives Glioblastoma Survival and Chemotherapy Resistance: Potential as a Promising Liquid Biopsy Biomarker. Full text: https://ajp.amjpathol.org/article/S0002-9440(24)00476-0/fulltext

#Neurodegenerative Theme Review: Multiple Roles for Neuregulins and their ERBB Receptors in Neurodegenerative Disease Pathogenesis and Therapy. Free to read: https://ajp.amjpathol.org/article/S0002-9440(25)00119-1/fulltext

#ArticleinPress: Inactivation of Atp7b Copper Transporter in Intestinal Epithelial Cells Is Associated with Altered Lipid Processing and Cell Growth Machinery Independent from Hepatic Copper Accumulation and Severity of Liver Histology. #OpenAccess text: https://loom.ly/DQjr5fI

Novel Perineural Pathways and the Dynamics of SIV-Infected Macrophage Trafficking Out of the Central Nervous System. Authors from @bostoncollege.bsky.social Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00325-6/fulltext

#ArticleinPress: Specialized Pro-Resolving Mediators MaR1 and LXA4 Resolve Inflammation During Acute Chemical Lung Injury in the Absence of Neutrophils. From @asipath.bsky.social member Bill Muller. Full text: https://loom.ly/pCpWpvw

#Neurodegenerative Theme Review: Shared Mechanisms of Blood-Brain Barrier Dysfunction and Neuroinflammation in COVID-19 and Alzheimer’s Disease. Authors from @tulaneu.bsky.social Free to read: https://ajp.amjpathol.org/article/S0002-9440(25)00118-X/fulltext

#Neurodegenerative Theme Review: The Biological Intersection Between Chemotherapy-Related Cognitive Impairment and #AlzheimerDisease. @bcmhouston.bsky.social #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00026-4/fulltext

Read the latest #PressRelease from @ajpathology.bsky.social and @elsevierconnect.bsky.social: New Study Elucidates Obesity’s Role in Fueling Breast Cancer Progression. Full release: https://shorturl.at/dkGNS

#Neurodegenerative Theme Review: Brain Connectivity, Neural Networks, and Resilience in Aging and Neurodegeneration. From @asipath.bsky.social member Dr. Christi Kolarcik. Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00027-6/fulltext

#Neurogedenerative Theme Issue: Updates on tau-related drug targets and potential disease-modifying therapies for Alzheimer’s disease. From @asipath.bsky.social Next- Gen Member Dr. Jessica Fortin and colleagues. Full text: https://loom.ly/t67JpU8

Deadline extended! The Spatial Pathobiology #callforpapers is still open. Submit your work by November 30th for inclusion in this upcoming theme issue. https://www.editorialmanager.com/ajpa/default2.aspx

Recent Advances in Chronic Traumatic Encephalopathy. Authors from @bumedicine.bsky.social Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00295-0/fulltext #Neurodegenerative Theme Review

#Neurodegenerative Theme Review: Current Advancements in Digital Neuropathology and Machine Learning for the Study of Neurodegenerative Diseases. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00046-X/fulltext

Exploring Vascular Contributions to Cognitive Impairment: Small vessel disease of white matter and micro/nanoplastics. From @asipath.bsky.social member Elaine Bearer. Full text: https://ajp.amjpathol.org/article/S0002-9440(25)00294-9/fulltext.

#Neurodegenerative Theme Review Genetically Engineered Mouse Models for Alzheimer Disease and Frontotemporal Dementia: New Insights from Single-Cell and Spatial Transcriptomics. Authors from @keck.usc.edu Full text: https://loom.ly/pWmHil0

#LegacyContent: Glucocorticoid Receptor Signaling Is Critical for Mouse Corneal Development, Inhibition of Inflammatory Response, and Neovascularization of the Cornea. Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(24)00236-0/fulltext

DEADLINE EXTENDED! Spatial Pathobiology #Callforpapers new deadline: November 30, 2025. Submit your work today: https://www.editorialmanager.com/ajpa/default2.aspx

The November issue of AJP is now live! This is a special issue focused on neuropathology. Full issue: https://ajp.amjpathol.org/issue/S0002-9440(24)X0012-7 On the cover: Astrocytes engaging with fibrillar amyloid in rTg-D HOM rats with cortical dyshoric vascular amyloid

Read the latest #PressRelease from @ajpathology.bsky.social and @elsevierconnect.bsky.social: Researchers Identify Perineural Pathway That Fuels HIV Persistence Despite Treatment. Full release: https://shorturl.at/x1kYh

Day two of #PISA2025 begins at 12:30 PM (ET)! Don't miss this special session with Dr. Evan Delgado (MUSC) and Dr. Bryan Wakefield (@uwmadison.bsky.social). Register for FREE here https://loom.ly/polGljk#PISA2025#CareerDevelopment #PathobiologyResearch

#LegacyContent: Caspase-1 Inhibition Ameliorates Photoreceptor Damage Following Retinal Detachment by Inhibiting Microglial Pyroptosis #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00242-6/fulltext

#LegacyContent: Artificial Intelligence-Based Histopathological Subtyping of High-Grade Serous #OvarianCancer. Free in the #OpenArchive: https://ajp.amjpathol.org/article/S0002-9440(24)00243-8/fulltext

#ArticleinPress: Intra-host genomic variation of Haemophilus influenzae isolates from asymptomatic nasopharyngeal carriers involves genes encoding proteins with diverse inferred functions. #OpenAccess text: https://loom.ly/1s7mAIM

#LegacyContent: Sequential Patching Lattice for Image Classification and Enquiry: Streamlining Digital Pathology Image Processing. Authors from @mayoclinic.org. #OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(24)00238-4/fulltext