🧪 Thought of the day: Penned by me: "An abstract Abstract doesn't age well". Or does it? #science #NobelPrize #abstract

📣 Don't miss this new Review! Interplay between RNA-protein interactions and RNA structures in gene regulation 🔓 buff.ly/pu6TpVa 🖊️ @rnaminni.bsky.social #RBPs #RNA #RNAbiology #RNAbindingproteins #RNAbinding #RNAstructure

Hello RNA world! Any new news?

MtDNA incorporating ribonucleotides and not deoxyribonucleotides increases inflammation. Interesting article: x.com/davidasincla...

#rnabiology #rna

PRC2 inhibition by sequence-specific RNA. Interesting! doi.org/10.1101/2024...

🧪Intellectuals, Selection for the prestigious National Academy of Sciences (India) Membership is a joy! Yours truly, Ph.D, MNASc 😀 Grateful to everyone who have stood by me rock solid in this scenic and transformative journey. Heartfelt Thank you to The National Academy of Sciences, India...

Happy to share our latest paper using machine-learning-QSAR on ChEMBL dataset. We identified and designed novel inhibitors for Acid Ceramidase inhibition in Glioblastoma using SHAP-based mechanistic interpretations. Thankful to proactive Reviewers and Editors. rdcu.be/exD3a

Interesting, so sharing here: x.com/nlarusstone/...

It is always mind boggling at how massive @agu.org is every year. This is just one session of the poster room, which changes over twice daily for the duration of the conference. #AGU24

And here I was wondering RNA Capping at the first mention of the word 'cap'...caps impart efficient translation and stability to mRNA... 🤔

The great Matterhorn in all its glory… A classic shot from the Swiss alps, but the light was too good to not click this one. #bluesky #photography #mountains #nature #landscape #landscapephotography #naturephotography

RNA-mediated DNA damage repair: www.nature.com/articles/s41... #RNAbiology #RNAsky

#RNABiology #RNAsky #tRNA

RNA aficianados, Just attended my first seminar series at RNA Collaborative - The RNA Institute, SUNY University at Albany yesterday. It is awesome science and a great way to stay updated in everything RNA. Registration is free: www.rnasociety.org/rna-collabor... #rnabiology #rnasky 🧪

Here is a paper where I would just like to say "Thank you" to the authors. I thoroughly enjoyed this. I hope you do too. #GENESky #RNAsky #CANsky #genomics #bioinformatics 🧪 🧬💻 🔎 microproteins www.cell.com/cell-reports...

Is 108 kb Air the longest lncRNA? Any new champion in this category?🤔 #rnabiology #rnasky 🧪

Molecular dynamics aficionados! Which is the most accurate RNA force-field currently? #rnabiology #computationalbiology #rnasky 🧪

Deers and LncRNAs... www.nature.com/nsmb/volumes... #rna #rnabiology

Got birds? Reply or quote this with your pics; we’d love to see them 📷🪶

Let's make a thread of RNA-related conferences in 2025 🧵 (add missing!)

@ijayas.bsky.social please add me to Biophysics starter pack. Thanks.

🧪 Transcriptome-wide CRISPR screens reveal essential lncRNAs: www.cell.com/cell/fulltex... #rnabiology

I am struck by a moment of sonder as I gaze around the @bluesky #bluesky

🎯 Our focus: TIM50, a mitochondrial import receptor with 7 consecutive prolines. When eIF5A is depleted, ribosomes get seriously stuck here - creating a traffic jam up to 300 base pairs long!

'On the evolutionary timescale, accumulation of L1 & SINEs occurred via multiple “explosions” when, during rather short evolutionary times, numerous insertions of retroelements entered genomes of our ancestors creating structurally distinct subfamilies of L1s & SINEs.' www.pnas.org/doi/10.1073/...

I know there are prediction tools for MHC and T cell Binding. Any computational tools for predicting T cell response? 🧪

Two high school students wanted the cash prize 🏆 for a math contest. They discovered new profs of the Pythagorean theorem, presented it at conferences, and published it in a journal - which has an awesome “Conclusion” section with the backstory: www.tandfonline.com/doi/full/10....

If you are interested in biological evolution in its many guises and aren't following Will, you're REALLY missing out 🧪

PDB depositors provided an enormous wealth of open access 3D structure data that helped drive breakthroughs in protein structure prediction More at Open-access data: A cornerstone for artificial intelligence approaches to protein structure prediction www.cell.com/structu...

Delighted are we too!! Our studies on lncRNA actions on gene regulation in pan-cancer system.... 1.RNPS1 among others: doi.org/10.7717/peer... 2. MALAT1 among others:https://doi.org/10.1038/s41598-022-11214-8 3. MALAT1-RNPS1 complex in alternative splicing:http://dx.doi.org/10.1021/acsomega.4c04467

New function for an 'old' chromatin remodeler: great collaboration with @nitikataneja.bsky.social and others. Fantastic work from our own @nhoitsma.bsky.social. Check out how SMARCAD1 contributes to resolving R-loops during replication, before they become a problem. www.biorxiv.org/content/10.1...

"Epigenetic control and inheritance of rDNA arrays" New preprint from the T2T acrocentrics team! We find a tight link between methylation and transcription of the rDNAs, including the occasional silencing of entire arrays www.biorxiv.org/content/10.1...

Bluesky now has over 10 million users, and I was #8,673,690! Arrived at last! 😄

5/ This work is a definitive statement on the capacity for small ORFs to produce the highest quality evidence in mass spectrometry data. In collaboration with GENCODE and PeptideAtlas, these ORFs and peptides will be supported for public view and public research resources.

Multi-pass, single-molecule nanopore reading of long protein strands https://www.nature.com/articles/s41586-024-07935-7 🧬🖥️ https://github.com/uwmisl/PASTOR-sequencing

Pollex, T., Marco-Ferreres, R., Ciglar, L., Ghavi-Helm, Y., Rabinowitz, A., Viales, R. R., Schaub, C., Jankowski, A., Girardot, C., Furlong, E. E. M. (2023).. Chromatin gene-gene loops support the cross-regulation of genes with related function. Mol Cell. www.cell.com/molecular-ce...

Our latest paper doi.org/10.7554/eLif... directly measures the "effective population size" that matters to nearly neutral / drift barrier theory, as the degree to which codon bias differs from expectations from GC content. Surprisingly, stronger natural selection -> more disordered proteins 1/

Love to see it: communities of scientists are forming on Bluesky. This is a nice network analysis, complete with a leaderboard mikeyoungacademy.dk/communities-...

The fruit fly Drosophila has been and continues to be a place where exciting new discoveries are made in all areas of biology. For example, we now have the entire "connectome" of its brain, with all neurons and neural connections identified. 1/n 🧪 www.science.org/doi/10.1126/...

It has been my joy to see our ACS-funded Diversity in Cancer Research internship program grow and thrive over the past 4 years. So proud of our exceptional students and supportive mentors! 🧪 #womeninSTEM lombardi.georgetown.edu/lombardi-sto...

Hearing someone who has seen science change so much in his 90+ year lifetime is a gift 🧪

There is a rich vein of great stories in the history of botanical names & Carol Ann McCormick of the NC Botanical Garden often delves into this area. This months installment, "Wandering with Whitlow-wort: what do flowers & fingernails have in common?" is a classic 🧪🌿 1/n ncbg.unc.edu/2024/08/29/w...

New Brain watercolors artologica.etsy.com 🧪🐡🧠

Apertif galaxy of the weekend: a beautiful blue spiral with arms that appear swept to the south, interacting with a warped, edge-on galaxy. Color image from PanSTARRS, white contours show the atomic hydrogen (HI) gas. Velocity map shows how the gas is rotating: blue towards us; red away. 🔭 📡 🧪

Excited to share our latest paper in PLOSCompBiol @plos.bsky.social ! journals.plos.org/ploscompbiol... Our study dives into the comparison of possible extracellular polysaccharide degradation strategies and their impact on microbial growth and community dynamics. 1/6 #Microbialecology

In its prime, my twitter "Scientists Who Do Climate" list had 3300 members—and now it’s here! 🎉 I’ve already id'd 350 researchers across physical, life + social sciences—and I'm just getting started. Huge thanks to @graocat.bsky.social for managing the list while I do the curating. Sign up here 👇