It's actually snowing in Amsterdam today ha amsterdamexperiences.nl/blog/ai-and-...

Learned today that New Year’s Eve in Amsterdam is absolutely insane

Cornwall, Oxford and London Holidays!

OpenEvidence valued at >$10B with $100M in revenue. Not much in this post about if it improves patient care..but that's old hat www.linkedin.com/posts/ethan-...

This month's @natrevmicro.nature.com is fantastic! Here @amsterdamumc.bsky.social, my team is building from scratch a next-gen clinical micro informatics infrastructure to support real-time pathogen surveillance; explicitly connecting the hospital to public health www.nature.com/nrmicro/volu...

Today I am very proud to announce the release of the Antibiotic Resistance Microbiology Dataset - Mass General Brigham (ARMD-MGB; physionet.org/content/armd...) , as part of an NIH-funded collaboration led by Jonathan Chen at Stanford. (1/6)

When you can watch an entire series with a thoroughly unlikeable main character, you know the director and actor have done an amazing job! Also, the attention to detail in the set pieces somehow manages to capture the beauty of that time and place without empty sentimentality, brilliant

www.huffpost.com/entry/histor... No easy solutions, but a lot of excellent points. It may be that tomorrow’s leaders will be those who have the courage to fail

Now out in @natcomms.nature.com Kudos to @tylim.bsky.social and @jameshay.bsky.social for a huge effort and thanks to all the collaborators for their hard work. See the final version here: www.nature.com/articles/s41...

This week is World #AntimicrobialResistance Awareness week This article collection spans the breadth of #AMR across pathogens (bacteria, viruses, fungi, parasites), covers epidemiological monitoring, diagnostics, treatment, etc

The role of AI in infectious diseases is emerging—offering new opportunities for infection prevention, detection & control. Explore developments & practical applications ⤵️ spkl.io/63323Ad83c @thelancetinfdis.bsky.social #WorldAMRAwarenessWeek

If successful for drug delivery, this could be really be helpful for minimizing adverse effects of treatment for infections… question is, can it get into a non-vascular space? (Ie abscesses or granulomas)…and can it be done cheaply so that we all can use it?

Thank you @tedpak.bsky.social for publishing the code for the LLM medical concept extractor you built for our recent paper! 2 things make this significant: a) This isn’t done enough in translational research and b) it’s designed for general use (ie Dockerized). Superb! github.com/tpaklab/llacie

Our lab's paper describing the North American H5N1 epizootic is out now in Nature! So thrilled to have this out, and congratulations to @lambod50.bsky.social for all the fantastic work on this: www.nature.com/articles/s41...

Gave my 1st talk in NL: how to make multicenter data analysis with patient data actually work. tl;dr: common data models (global interoperability) + LLMs (data harmonization, mapping, future-proofing) + federated learning (privacy) Let me know what you think! drive.google.com/file/d/1N3yk...

Last chance world! Application closes tomorrow!

Really happy to see this out! Congrats @tedpak.bsky.social on an important and top notch piece of research! jamanetwork.com/journals/jam...

This article doesn't explicitly say what (I think) many of us who practice/d in the US implicitly understand / feel, which is that health disparities, inequity and sickness are a feature, not a byproduct, of the US healthcare system. They are highly profitable www.thelancet.com/journals/lan...

Hey world, we have an opening for a PhD candidate in my lab! Come join our team in Amsterdam and help build an AI learning health system for infectious diseases (along the way eat some haring and get your bike game on) werkenbij.amsterdamumc.org/nl/vacatures...

www.nts.live/shows/dont-a... Don’t Assume!

D'Angelo's music oeuvre is incredible but it was his song Africa that changed my entire perspective about what is possible with music. The acoustic demo version lifted the song to a new level, which I didn't think was possible. A true genius 🥲 www.youtube.com/watch?v=NlcA...

It’s 2am. Do you know where your public health agency is?

www.nature.com/articles/s41... Awesome to be a part of this project to publish a huge EHR dataset of patients with/without AMR for the research community An equally large *harmonized* EHR dataset from my previous center (Mass General Brigham) is forthcoming & will allow for multicenter validation!

Journals and publishers crack down on research from open health data sets www.science.org/content/arti... There's a meta-story here about the generation of knowledge in the 21st century and the (immense) resources it takes to ensure it is of high quality. It is / should be an industry unto itself

open.substack.com/pub/jmarriot... Dark futures ahead, but also some narrow paths to light

Imagine we could travel back in time ⏪⌛️to explore the world of bacterial pathogens before humans discovered and industrialised antibiotics We just did that to study the history of #AMR spread @science.org doi.org/10.1126/scie... If you like time travel & biology, this 🧵is for you👇

Science is fun, but the history of science is even...funner! -Originally considered by Allied scientists in World War II, it proved so intractable that...the problem was proposed to be dropped over Germany so that German scientists could also waste their time on it en.wikipedia.org/w/index.php?...

A stroll around the new hood

Historically, viruses were thought to primarily use host cell's translational machinery. New work from @harvardcellbio.bsky.social faculty Amy Lee reveals that a giant DNA virus encodes its own IF4F initiation complex, suggesting an unexpected evolutionary innovation. www.biorxiv.org/content/10.1...

arcinstitute.org/news/hie-kin... Besides the really cool biology, it's also a very nice lay summary of their bioRxiv preprint...good precedent for the rest of us

bmjopen.bmj.com/content/13/9... Great to see the field maturing!

That's a stage being setup...inside @amsterdamumc.bsky.social...where the hospital's band (yup), play a concert once or twice a year. How about that!

As national medical, scientific, public health and patient organizations, we call for the resignation of HHS Secretary Robert F. Kennedy Jr. to ensure the health of the American people. Our statement: https://bit.ly/45LeJHi

The appearance of large language models caused a drastic shift in the vocabulary of academic writing, according to an analysis in #ScienceAdvances of more than 15 million biomedical abstracts published from 2010 to 2024. Learn more:

Rates of infection with other pathogens after a positive COVID-19 test versus a negative test in US veterans (Lancet ID) www.thelancet.com/journals/lan... Such a cool article; cross-species / -kingdom interactions provide a deeper understanding of the true implications of infection

🚨 IDSA has released the first guidelines for the management and treatment of complicated urinary tract infections (cUTIs)! The new guidelines simplify the prior definitions of uncomplicated UTIs and cUTIs, & address treatment for cUTIs. View guidelines: bit.ly/4lUjN1a

Seeing this published is even better than eating sweets! I am so happy and proud of whole @lisamaierlab.bsky.social, especially Lisa and @jdlcz.bsky.social who walked the funny/exciting/rocky road with me until the very end. Check it out! #science #microbiome #health www.nature.com/articles/s41...

A 20 year journey finishes today: I paid off my med student loans! Thank you www.lrp.nih.gov, without you I never could have dug out of my >quarter million $ hole and stay a physician scientist

I gave my final didactic talk to the @mgb-id-fellows.bsky.social fellows yesterday on treatment of MDR GNRs. Really active area of research! Have a look! I welcome corrections. drive.google.com/file/d/170xP...

Excited to share some key details on our latest research in @natmicrobiol.nature.com reporting intra-cellular accumulation of #PFAS (aka forever chemicals) by certain human gut bacteria. #microsky #mevosky #microbiomesky www.nature.com/articles/s41...

Yesterday was my last day attending at my hospital. My tenure began and ended as all things begin and end: with Staph

I feel you dude

Reason #4523 for why we are excited to move to the Netherlands

Ever review a nice manuscript from a distinguished author that in the discussion section, completely fails to put the paper into context? This SCOTUS decision makes sense only when you have an executive branch that cares about the people of the US. Obviously? www.nytimes.com/2025/06/28/o...

Super interesting field of work…though the converse question of how antibiotic-mediated perturbations of the microbiome influence cancer risk, is just as, if not more, important from a risk standpoint. Easier to modify antibiotic exposures.

The 𝘑𝘰𝘶𝘳𝘯𝘢𝘭 announces a series focused on preparation of future physicians for clinical practice in light of ongoing disruptions affecting clinical care. The series aims to stimulate new ways of thinking and provide guidance to frontline clinician–educators. Learn more: nej.md/4lgVFGl

This is a travesty & a nightmare. The US was a founder of @gavi.org. It lowers global vaccine costs, has vaccinated 1B children, & averted 19M deaths. This pull out will cost 100s of thousands of children's lives a year - and RFK Jr will be personally responsible. www.politico.com/news/2025/06...

*Shameless call for alpha-testing our AI tutor for microbiology / ID* Hey all, I'm looking for folks would have interest in providing end user feedback on our AI tutor targeting 2nd year preclinical med students. Clinical knowledge helpful but not required. If so, DM me for the deets!

jamanetwork.com/journals/jam... tl;dr "routine vaccination of approximately 117M children from 1994-2023 likely prevented around 508 million lifetime cases of illness, 32M hospitalizations, and 1 129 000 deaths, at a net savings of $540 billion in direct costs and $2.7 trillion in societal costs"

Waterbury VT shows up!