📢 #KRAS degradation induces rapid lung #cancer regression in preclinical mouse models: A study by #IRBBarcelona & @ciccancer.bsky.social demonstrates that eliminating mutated KRAS protein using #PROTACs induces rapid tumour regression in mouse models of lung adenocarcinoma. ➡️ https://bit.ly/4dFWhm1

El equipo del @ciccancer.bsky.social ( @csic.es, @usaloficial.bsky.social, FICUS), dirigido por David Santamaría, en estrecha colaboración con investigadores del @irbbarcelona.org, han desarrollado un modelo preclínico de cáncer de pulmón en ratón.

🧪 Chem(bio) friends, this one is big!!🔥 @irbbarcelona.org is opening a Group Leader position in Chemical Biology! 💜 If your research plan and vision are at the interface of synthetic chemistry, chemical biology, and biomedicine, please check the call! 👇 recruitment.irbbarcelona.org/jobs/7334978...

SS18::SSX activates Polycomb target genes without BAF ❌ Instead, transcription relies on EP300 via the SS18 QPGY domain www.biorxiv.org/content/10.6... ➡️ Coactivator targeting emerges as a new therapeutic strategy in synovial sarcoma 🎯 Team work from @banitolab.bsky.social and @uoe-igc.bsky.social

🤝 #IRBBarcelona Group Leader Cristina Mayor-Ruiz has co-authored a Perspective in #MolecularCell proposing the creation of a #EuropeanAlliance to accelerate the development of proximity-induced therapies. More information here 🔗 www.irbbarcelona.org/en/news/scie... 🧪 #TargetedProteinDegradation

📷 Photo 51 — the image that changed the course of science. Taken by British chemist and crystallographer #RosalindFranklin (born on this day in 1920) and Raymond Gosling, this X-ray diffraction image of DNA was the key to unlocking the double helix structure. #WomeninSTEM

🔬Check out this recent spotlight in #MolecularCell, co-authored by Rory Whelan Ferran José Duran & @crismayorruiz.bsky.social— Mutations that stick: Unexpected discovery of molecular glue mimicry👇  ➡️ https://f.mtr.cool/zbljytwpcx #ChemBio #MolecularGlue #MolecularGlues 🧪

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🟣 On #WomensDay, we recognize the incredible women of #IRBBarcelona! Researchers, technicians, managers, and other professionals whose talent and dedication push the boundaries of knowledge. Your work fuels discovery and paves the way for future generations of women in science. Thank you! 🙌 #8M

🧪 #Barcelona

📌 La Dra. Ana Domostegui desarrolla un nuevo tipo de fármacos innovadores, denominados fármacos degradadores de proteínas, para el tratamiento del #CáncerdePáncreas.

📌 PROTECT: En el marco de @cancergrand.bsky.social, el proyecto liderado por la Dra. @crismayorruiz.bsky.social desarrollará fármacos degradadores de proteínas para luchar contra los tumores pediátricos.

🟢 Ha sido un honor asistir hoy a la presentación de las Ayudas 2024 de la Asociación Española Contra el Cáncer. ¡Gracias Asociación Española contra el Cáncer por acompañarnos en este compromiso! Cada paso juntos nos acerca a un futuro sin #cáncer. Descubre los proyectos del @irbbarcelona.org: 🧵👇

Avui hem tingut l’honor de rebre la visita de la consellera de Salut, Dra. Olga Pané. Ha conegut de primera mà els plans de futur de l'Institut i la importància dels nous laboratoris TRIP, una innovadora forma d'apropar #recerca fonamental i clínica. Gràcies, consellera!

Hello, Blueskyers! Here's a comprehensive Starter Pack featuring all the IRB Barcelona faculty and affiliated members currently active on Bluesky. Keep an eye on this space—we'll be regularly updating it as more of our researchers join the platform. Thanks for following us! go.bsky.app/6QPdeJj

Happy #WomenScienceDay! @irbbarcelona.org 🧪 youtube.com/shorts/p3rRs...

We are creating a dedicated website to honor the memory of Dr. Joan Guinovart and celebrate his remarkable legacy✨  Contribute by sharing your message through this form: ➡️ http://shorturl.at/YQn1l  Join us in paying tribute to his extraordinary impact.

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Our lab wishes you all a Merry Christmas! We finish the scientific year at the @irbbarcelona.org Christmas party with the best costume ever!! 🤣🤣🤣

Hi BlueSky world! We are thrilled to share our new preprint around oncoprotein degradation in vivo —a fantastic collaboration with our friends in Salamanca #lab_santamaria #ciccancer! 😃 @irbbarcelona.bsky.social #TPD #KRAS 👇 www.biorxiv.org/content/10.1...

Women in chemistry starter pack here: go.bsky.app/LjumNEg #ChemSky please repost :D #ChemSky #realtimechem #FluorescenceFriday

📯📯 Chemical Biology starter pack 📯📯 140 PIs & groups posting primary research in chemical biology. Please reskeet (?) & reply to this post if you want to be added! go.bsky.app/KLrTWoj Let's make ChemBioSky even greater again! #realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange

Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️ go.bsky.app/3VPQofn