The #spatial architecture of disease www.nature.com/articles/s41...

Cancer is an evolutionary disease, but does knowing a cancer’s evolutionary past help predict its future? Out today in @nature, we learnt the evolution of 2000 lymphoid cancers and found it was highly correlated with clinical outcomes! (1/7) rdcu.be/eFrrc

Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...

Communication in pathology, the power of word. Excellent keynote at #ecp2025 in #vienna!

So accurate, it hurts

Happy to share our preprint on #pancreatic #cancer using a combined #digitalpathology #ish #ihc approach! www.researchsquare.com/article/rs-6...

Fantastic workshop on the ecology and #evolution of cancer #EBEC2025! So thrilled and proud to have been part of it! @sangerinstitute.bsky.social #cambridge

Looking forward to the "Evolutionary Biology and Ecology of Cancer" course in #Cambridge at the #wellcome genome campus! #genomics

Tour de force from @melissabarroux.bsky.social on evolutionary and microenvironmental dynamics of oesophageal adenocarcinoma through neoadjuvant therapy Published @natcancer.nature.com Melissa is an outstanding new clinician scientist.. one to watch. www.nature.com/articles/s43... @icr.ac.uk

dATAC: our new method for simultaneous very high quality whole genome sequencing and chromatin accessibility profiling of single cells. We used dATAC to trace epigenome clonal evolution in colon cancer. Devised by the extraordinarily talented @maxmossner.bsky.social www.biorxiv.org/content/10.1...

www.nature.com/articles/s41... I enjoyed the read!

Pancreatic cancer and its spatial TIME: Lots to learn and to do! www.sciencedirect.com/science/arti...

#pathsky Excellent talk on pancreatic neuroendocrine neoplasms at the Spring Meeting of the Austrian Society for Pathology y Konstantin Bräutigam @pathologop.bsky.social #oegpath

Happy to be part of "Immunocto", a massive immune cell database in a H&E/IF approach! arxiv.org/abs/2406.02618

Neuroendocrine Tumors? No problem! link.springer.com/article/10.1...

⏰preprint alert⏰ I am very happy to share our recent preprint on targeting metabolism in Pancreatic Neuroendocrine Tumors via lactate transporters MCT1/4! www.biorxiv.org/content/10.1... Incredible amount of experimental work, many thanks to all contributors and especially to the seniors!

Are you using #AI to analyse #Histopathology images? A team of ICR researchers have created a glossary to help AI developers understand tumour histopathology. They hope that this will speed up the development of AI algorithms for cancer research ⤵️ doi.org/10.1371/jour...

Meeting Darth Vader at the #festivalofgenomics! #genomics #excel #london

Thanks @trevorgraham.bsky.social ! We hope to fill this gap and to boost #cancer research! #ai #pathology

Our survey on routine #TIL reporting has finally been published open access in "Pathology-Research and Practice"! www.sciencedirect.com/science/arti... Many thanks to the 77 participants from all over the world, we are grateful for your participation! #pathology #tme #oncology

link.springer.com/article/10.1... The #pathologist role in trials.

Traveling in time to my alma mater, Charité Berlin.

Inaugural Meeting of the European Society for #Spatial #Biology in Berlin! Lovely venue and excellent line-up! #essb

Beautiful commentary on the importance of cell function in a "genocentric" age. www.cell.com/cell/fulltex...

We have an open #PhD #studentship as part of our "Black Leaders in Cancer" programme at @crukconvergence.bsky.social & @icrlondon.bsky.social. About computational modelling of T-cell evolution in cancer. www.findaphd.com/phds/project... I'm looking forward to meeting prospective students #CRUKfunded