TaoChongBao: A Large-Scale Caenorhabditis elegans Mutagenesis and Missense Variant Database Bridging Worm and Human Genomes https://www.biorxiv.org/content/10.64898/2025.12.03.692224v1

So excited to post my first official #zebrafish paper in my new gig at UC Berkeley with my amazing co-authors @swinburnelab.bsky.social @alinetschanz.bsky.social The TL;DR is that monomeric StayGolds are game changers for in vivo imaging in zebrafish 1/7 micropublication.org/journals/bio...

WormTagDB: A Systematic Survey of Endogenously Tagged Proteins in C. elegans and Roadmap Towards the Tagged Proteome https://www.biorxiv.org/content/10.64898/2025.12.02.691955v1

Grateful to be featured in Nature Methods discussing how @danstarrucdavis.bsky.social and I run the joint Starr-Luxton Lab @ucdavis.bsky.social together. Thanks to Vivien Marx for the thoughtful interview - she really captured what makes this model work. www.nature.com/articles/s41...

This year’s #NobelPrize in Physiology or Medicine has been awarded to three scientists for discovering how the immune system distinguishes friend from foe. https://scim.ag/3Wt5rdi

This year’s Nobel Prize in Physiology or Medicine has been awarded to three scientists for discovering a class of immune cells that help to prevent the body from attacking its own tissues go.nature.com/48QDdAJ

Write your program officer and grants management official TODAY and thank them! It takes 30 seconds and its really appreciated. The only reason they're remotely this close is because those folks are working 60 hour weeks under immense pressure

🎉Check out our new preprint!! 🧬We found that lamin mutations in muscular dystrophy don’t just affect the nucleus — they disrupt a nucleolar–ribosomal axis that reorganizes the entire cytoplasm. Very grateful to @danstarrucdavis.bsky.social, @gwgl.bsky.social and our lab for collaboration & support!

🧬 NEW Starr-Luxton Lab PREPRINT: Our 🌠grad student @XiangyiDing figured out why muscular dystrophy mutations cause such widespread cellular chaos. The answer wasn't what we expected - and it changes how we think about the disease. Thread🧵 (1/6). www.biorxiv.org/content/10.1...

Centrosomes might look tough, but they are actually big softies - see the latest work from the Dammermann lab now on BioRxiv:

Congrats to @xiangyiding.bsky.social et al. on their new study on the intense cellular dance happening in worm cells! 🕺 Dive into the #FrontierScience of organelle crowd control. 👇

🧬Want the full story of our paper without the science jargon? Our @ucdavis.bsky.social department broke down our "cells are crowded AND constrained" findings in plain English! Perfect explanation of why worm cells are nothing like cultured cells 🪱🌠

🧬BREAKING!🪱Plot twist: Cells aren't meditation pools, they're overcrowded concerts with VIP ropes everywhere! Our study reveals worm cells are insanely crowded AND compartmentalized. Ribosomes = packing peanuts, ANC-1 = the bouncer! www.science.org/doi/10.1126/...

🚨Our fabulous graduate student Selin's paper on how the KASH protein UNC-83 regulates the activity of kinesin-1 to control developmental stage-specific nuclear migration is out! Another great collaboration between the Starr-Luxton and MOM labs. www.sciencedirect.com/science/arti...

2025 Worm Show youtu.be/HXgUZzLJ-b0?...

Our review is out! Such an honor to publish with Ryoko and Michael-early midbody leaders! The midbody and midbody remnant: from cellular debris to signaling organelle with diagnostic and therapeutic potential www.molbiolcell.org/doi/full/10....

Congratulations to Dr. Gümüşderelioğlum from the Starr-Luxton Lab @ucdavis.bsky.social! 🎓 Fresh off her recent PhD defense, she gave an excellent talk this morning at the Cell Biology session of #Worm2025 on UNC-83 molecular switches in nuclear migration. So proud! 👏 #NewPhD #CellBiology

Incredible plenary presentation by Starr-Luxton Lab student @xiangyiding.bsky.social at the International Worm Meeting! Who knew C. elegans cytoplasm has the viscosity of strawberry jam? 🍓 So proud! #Worm2025 #frontierscience @danstarrucdavis.bsky.social

So nice that you encouraged her to apply. Oh and she is also in this teeny-tiny blog post. Still in the works. communities.springernature.com/posts/when-s...

Amazing to see our student @xiangyiding.bsky.social featured in Nature Methods discussing how the Marine Biological Laboratory Physiology course transformed her approach to research! So proud of her experience and growth. #Frontierscience 🪱💎

Ellen Gregory, @gwgl.bsky.social‬, & @danstarrucdavis.bsky.social‬ show how heterochromatin helps cell nuclei migrate through tight spaces in #Celegans! Learn more in #GENETICS about the process of heterochromatin anchoring to the nuclear periphery that supports nuclei squeezing: buff.ly/kZttVdX

🧵 1/8: Excited to share our new paper on how heterochromatin (tightly packed DNA) helps cell nuclei migrate through tight spaces in #Celegans! Published in @genetics_asa #CellBiology #NuclearMigration pubmed.ncbi.nlm.nih.gov/40335054/ Congrats @danstarrucdavis.bsky.social and 1st author Ellen!

8:30 pm PST. MARKET CRISIS DEEPENING. Hang Seng falls 9.96% while HSI Volatility Index surges 43.63%. Nikkei stabilized at -6.48% after earlier -7.56% drop. What began as Japanese banking stress has become full regional contagion. Asian markets now facing their worst session since March 2020.

This implies Trump will impose an across-the-board tariff rate of 15% on all goods and services imported into the United States on April 2.

SCARY TARIFF THREAD We still don’t know what additional tariffs Trump will announce on April 2. He keeps calling April 2 as America’s “Independence Day.” Comments from Navarro about revenue forecasts imply he intends to impose an across-the-board 15% tariff on all goods coming into the US. 1/

🧬 NEW RESEARCH ALERT! Starr-Luxton Lab grad student Selin discovered how cells control nucleus movement using KASH protein UNC-83 isoforms as molecular switches. Critical for organ development and preventing genetic disorders! 🧪🔬 www.biorxiv.org/content/10.1...

science.org/doi/10.1126/... Just published! We uncovered a molecular machine that connects the cell's two major structural networks revealing how cells accomplish precise internal reorganization - a process disrupted in diseases ranging from cancer to multiple sclerosis.

see you next time

I got to be friends with David Lynch when we were both at Universal years ago. A very kind man, he was a fan of Bob's Big Boy. So was I. I'm going to miss him. R.I.P. David.

was mostly keeping it together until I read Kyle MacLachlan's tribute to David Lynch

I did cry a little, trying to express what’s so transcendently beautiful about Lynch’s work.

Noooooooo! www.bbc.com/news/article...

How are cells in living tissues different from those in a dish? This question has puzzled scientists for decades. In our new preprint, we studied C. elegans roundworms to uncover how cells maintain unique internal environments. The results surprised us. www.biorxiv.org/content/10.1...

The Starr-Luxton Lab woke up to fantastic news on the first workday of 2025! The NIH renewed @danstarrucdavis.bsky.social’s R35 grant. This multi-year award will help expand our collaborative research on nuclear positioning during development.

Happy New Year! I’m enjoying becoming a Californian!

Great job Starr-Luxton Lab graduate student Selin on both presenting your poster and giving a fantastic talk today! #CellBio2024