Egill Richard
@egillrichard.bsky.social
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Post Doc in Sam Sternberg lab at Columbia University Genetics - Microbiology
Excited to share the work thatās been on my mind for the past 2 years, now on bioRxiv! Led with Matt Walker, and my first project in the Sternberg Lab . Check it out ā¬ļø
tinyurl.com/mshwjd77
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Temperate phages enhance host fitness via RNA-guided flagellar remodeling
Bacterial flagella drive motility and chemotaxis while also playing critical roles in host-pathogen interactions, as their oligomeric subunit, flagellin, is specifically recognized by the mammalian im...
http://tinyurl.com/mshwjd77
2 months ago
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reposted by
Egill Richard
Sternberg Lab
2 months ago
1/16 New pre-print from the Sternberg Lab! We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness. Find the preprint and full story here:
tinyurl.com/mshwjd77
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reposted by
Egill Richard
Jose A Escudero
5 months ago
Our paper is published back2back with one from
@amazeld.bsky.social
and
@epcrocha.bsky.social
labs where
@baptistedarracq.bsky.social
,
@eloilittner.bsky.social
and co. show that Sedentary Chromosomal Integrons are biobanks of phage defense systems.
www.science.org/doi/10.1126/...
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Sedentary chromosomal integrons as biobanks of bacterial antiphage defense systems
Integrons are genetic systems that drive bacterial adaptation by acquiring, expressing, and shuffling gene cassettes. While mobile integrons are well known for spreading antibiotic resistance genes, t...
https://www.science.org/doi/10.1126/science.ads0768
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reposted by
Egill Richard
Yves Brun lab
7 months ago
Please repost: Postdoc position in antibiotic discovery in a large multidisciplinary project combining high-throughput approaches, microscopy, AI, and hit-to-lead optimization at
@umontreal.ca
and
@mila-quebec.bsky.social
. Apply to
[email protected]
. See
lnkd.in/dVVk4N3s
.
#microsky
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reposted by
Egill Richard
Marco Trujillo
7 months ago
Viral coat proteins are perceived by the RING1āIBRāRING2-type ubiquitin ligase (RBRL)
#PlantSci
#Ubiquitin
#proteostasis
www.nature.com/articles/s41...
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Perception of viral infections and initiation of antiviral defence in rice - Nature
Viral coat proteins are perceived by the RING1āIBRāRING2-type ubiquitin ligase, initiating the first step of the natural antiviral response in rice.
https://www.nature.com/articles/s41586-025-08706-8
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hello world
10 months ago
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reposted by
Egill Richard
Jose A Escudero
over 1 year ago
And its out! New paper for
#integron
aficionados. We found gene-less cassettes in superintegrons that express/silence other cassettes in the array. Here is a š§µ(if I know how to do this in Bluesky...š)
academic.oup.com/nar/advance-...
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Identification of promoter activity in gene-less cassettes fromĀ Vibrionaceae superintegrons
Abstract. Integrons are genetic platforms that acquire new genes encoded in integron cassettes (ICs), building arrays of adaptive functions. ICs generally encod
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad1252/7517494
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