Excited to share my PhD paper! In it, we use targeted 2-photon optogenetic stimulation to determine how V1 activity is read-out in a detection task. We found that network influence, not visual coding properties, predicted the impact of ensembles on behavior - contradicting our expectations (1/5).

Speak up! Important to register widespread opposition to transitioning NIH to funding ideologically-motivated science. If you want advancements in knowledge and eventual cures, it is critical that research is steered by knowledgeable scientists, not political appointees

🗣️AMPLIFY AMPLIFY AMPLIFY!!! Please comment!

Our new paper is out in Science. What is the synaptic plasticity rule in the brain, we asked. It turns out there are multiple, even within individual neurons. Congrats Jake! www.science.org/doi/10.1126/...

🚨iGluSnFR4 is finally out!🚨🧪 We present iGluSnFR4f and 4s, a novel pair of genetically-encoded glutamate indicators designed for high-fidelity imaging of synaptic activity in the living brain. ⬇️ www.biorxiv.org/content/10.1... 🎥 Below: iGluSnFR4s detecting minis in cultures w/ TTX #Neuroscience

Thrilled to share the latest paper from the lab! Huge congrats to first author Dr. Celine Drieu and the amazing team of Ziyi Zhu, Sarah Elnozahy, Joy Wang, Aaron Wang, and Kylie Fuller! Lots of fun stuff in the paper so check it out - and let us know what you think :)

1/7 Our paper on individual variability in decision-making is finally out in @nature.com! Inspired by the classic work by Mante and Sussillo, we trained many rats to solve context-dependent decision-making, and we found that different brains use different neural mechanisms to solve the same task!

Carl R. Olson (1944–2024) www.cell.com/neuron/fullt... #neuroscience

Join us for SAND in June - Abstracts due this Friday! The focus is on joining experimental and computational neuroscientists to drive progress in analyzing neural data

Check out our new paper, that reveals both the striking generality of cortical circuit organization, but also what we think are key differences in the scales of local excitatory and inhibitory networks across cortical areas. www.jneurosci.org/content/45/1...

I'm trying to make something- if your university is on the list, could you post here with your school's most famous public-facing discovery? e.g. for University of Pittsburgh: Salk polio vaccine Please repost! www.ed.gov/about/news/p...

Are you using GCaMP8 or are planning to switch from GCaMP6? Then check out this new preprint from our lab! www.biorxiv.org/content/10.1... - Calcium imaging - GCaMP8 vs. GCaMP6 - Spike inference - Imaging + ephys ground truth With F. Helmchen, K. Svoboda, M. Rozsa & X. Fang.

www.nature.com/articles/s41... awesome new work out today! From the Lee lab in the intramural research program at NIMH!

Can the mouse visual cortex harbor a functional organization for stimulus features? TLDR: Yes, we found ocular dominance columns in this tiny cortical region! Check our paper, open access in @naturecomms.bsky.social www.nature.com/articles/s41... and/or read the 🧵 below. @mpiforbi.bsky.social (1/7)

#StandUpforScience local rally in Pittsburgh is confirmed! 📅 March 7, 2025 ⏰ 11 AM-1:30 PM 📍Schenley Plaza, Pittsburgh Follow the local rally’s Instagram @savesciencepgh for updates Spread the word 🔥 @standupforscience.bsky.social #StandUpForScience2025 #ScienceForAll #ScienceNotSilence #STEM

📣 The 11th Statistical Analysis of Neuronal Data (SAND11) workshop will be held June 11-13, 2025 in New York at the @flatironinstitute.org with generous support from @simonsfoundation.org Submissions for talks+posters are due March 21. See our website for details 👇 sandworkshop.github.io