32% off ProxiMeta™ Hi-C kits ends 3/15 (then save 16% through end of month). You’ll get: ✅ High-quality MAGs from complex samples ✅ More complete genomes than traditional binning ✅ Accurate host attribution for phages, plasmids, and AMR genes 👉 info.phasegenomics.com/march-magness

March MAGness is here! Score special pricing on ProxiMeta™ Hi-C kits for metagenomics & microbiome studies in everything from complex soil samples, to gut microbiomes, to bioreactors: 🔬 32% off | March 2–15 🔬 16% off | March 16–31 Get started here 👇 info.phasegenomics.com/march-magness

FISH finds what it's looking for, and only what it's looking for. In a new study in @AjHematologyshows, Hi-C confirmed FISH findings, plus chromothripsis, CN-LOH & complex rearrangements that FISH probes can’t pinpoint. 🔗https://onlinelibrary.wiley.com/doi/epdf/10.1002/ajh.70219

New Nature Plants study using Proximo™ Hi-C shows how a hybrid eelgrass species inherited low-light tolerance genes from its deep-water parent that could change how we approach coastal restoration. More from Todd Michael, PhD & team at @salkinstitute.bsky.social l 📄 www.nature.com/articles/s41...

New Publication in @plosbiology.org: Optimized Hi-C analysis (Z-score filtering) boosts specificity & reveals virus-host interactions using Phase Genomics’ ProxiMeta™ Hi-C: 79 genus-level matches + 293 new linkages in well-studied, climate-critical soils. journals.plos.org/plosbiology/...

"A year and a half ago, we couldn't have resolved this hybrid genome." New tech (long reads + Hi-C) let researchers separate parental haplotypes in eelgrass revealing which genes drive low-light tolerance. Todd Michael, PhD breaks down how:

Phase Genomics IRL: a few days together in Portland for real-time collab & creativity. Aligning on new products, pressure-testing ideas, a little fun behind the wheel. It’s how we build even better Hi-C tools for the researchers who rely on them. A few of our favorite moments👇

Tissue prep drives variability early in Hi-C workflows. A new STAR Protocol adds cryogenic tissue grinding before crosslinking, with safe pause points for optimized lab workflows. See how it improves reproducibility & library quality → star-protocols.cell.com/protocols/4702

Wheels up ✈️ Our CEO Ivan’s headed to Newport Beach for Microbes in Wastewater. He’ll show how ProxiMeta™ links microbes, phages & the mobilome to track #AMR in wastewater. No coding. Just discovery. If you’ll be in Newport for the conference, say hi to @ivanliachko.bsky.social

We heard you. Our 25 in ’25 promo is extended through Jan 16. Save 25% on Phase Genomics Hi-C kits via direct order, book a complimentary bioinformatics consult, and access discounted full-service ProxiMeta™ packages. Get started → info.phasegenomics.com/25-in-25

Bees carry more than nectar. Their gut microbiomes buzz with plasmids, sharing tetracycline resistance genes across hives. Chris Robinson, PhD from Irene Newton, PhD’s lab used Hi-C to track these mobile elements & explore colony-specific patterns traditional metagenomics misses.

Stuck on Hi-C data? First 25 researchers to email get a free consult with our computational scientists—whether you're using our kits or another provider's. Email [email protected] with "25 in '25 Bioinformatics Promo" in the subject line to claim yours.

Save 25% on Hi-C kits through Dec 31. From complex plant genomes to metagenome binning, Phase Genomics brings clarity to your toughest research questions. Email [email protected] with "25 in '25 Kit Promo" in the subject line to claim your discount.

🌿 Scientists produced a high-quality, chromosome-scale genome for American pickleweed, a salt-loving, tetraploid marsh plant. With ~80k genes and detailed methylation data, this resource paves the way for understanding salt-tolerance & supporting salt-marsh conservation. 🔗 bit.ly/3XAQ7vT

New at #AMPath2025: He Fang, PhD, will showcase Genomic Proximity Mapping® (GPM) and CytoTerra® in #sarcoma. Stop by Level 2, 258ABC on 11/13 from 2:30 – 3:30 pm ET to discover how GPM uncovers hidden structural variants and mosaicism in challenging archival samples.

🌿 New in @NaturePlants! Researchers used Phase Genomics’ Hi-C to build a haplotype-resolved chromosome-scale #genome of a hybrid eelgrass (Zostera marina × Z. pacifica), revealing genomic clues to low-light tolerance that could boost coastal restoration. www.nature.com/articles/s41...

Big spotlight on Genomic Proximity Mapping® (GPM®) from Elsevier's JMD: See how UW researchers use our GPM platform, CytoTerra®, to detect cryptic structural variants and mosaicism missed by standard tests. Full press release from @elsevierconnect.bsky.social: www.elsevier.com/about/press-...

Phase Genomics Hi-C helped untangle the pomegranate genome, ordering contigs into chromosome-scale scaffolds, clarifying chromosome counts & revealing domestication patterns. Full study from the Volcani Center: link.springer.com/article/10.1...

Phase Genomics’ Hi-C tech helped undergrads assemble the “best duckweed genome yet,” giving them hands-on research experience, boosting PhD prospects, and advancing plant biology. Full story from Alex Harkess at HudsonAlpha on YouTube: na2.hubs.ly/H01P7mG0

Hi-C at scale is reshaping plant biology. With Phase Genomics’ kits, Alex Harkess & HudsonAlpha have published dozens of genomes, uncovered how rising CO₂ alters chromatin structure, and explored how climate change ripples through living systems. 🔗 youtu.be/5-Ub7FnpHzs?...

Happy #WorldPhageDay. Tiny, abundant, and anything but boring, phages shape microbial communities, move genes around, and can tip the balance in all kinds of ecosystems. The catch: to know a #phage only you must know its host. ProxiMeta Hi-C technology gives us that link.

🌳 New chromosome-level Ulmus minor (field elm) genome unlocks clues to Dutch elm disease resistance. Using long reads and Hi-C, the team built this 2.1Gb genome and mapped clusters of resistance genes conserved across elm species to aid restoration. na2.hubs.ly/H01HQ2Q0

ProxiMeta™ Hi-C fills the missing link in shotgun metagenomics, connecting viruses to hosts & revealing hidden microbial relationships. Hear more from Phil Hugenholtz & Phase Genomics CEO Ivan Liachko on how Hi-C unlocks the microbiome → www.youtube.com/watch?v=DYMv...

Skip the computational guesswork. Hi-C / proximity ligation reveal complete chromosomal architecture based on actual intracellular contacts. From plant genomes to metagenomes, Phase Genomics delivers chromosome-scale assemblies traditional methods can’t: phasegenomics.com/resources-an...

In this great new paper, the authors use metagenomic Hi-C to show that #phage with broad host range are fairly common, contrary to the prevailing view on their biology. Cutting edge methods like Hi-C are shedding light on our blind spots in the microbial world.

ProxiMeta™ turns your benchtop box into a Hi-C metagenomics powerhouse. Order before Sept. 30 to lock in 20% savings on the 8-sample ProxiMeta Classic Hi-C Kit, or 50% on the 2-sample ProxiMeta Starter Hi-C Kit. 🔗https://phasegenomics.com/contact-us/

Don’t let your lab’s grant dollars go to waste. Order before September 30 to save 20% on ProxiMeta™ Classic Hi-C Kit, or 50% on the ProxiMeta Starter Hi-C Kit. ✔️ Hands-off workflow ✔️ Flexible timelines ✔️ PGShield™ to keep samples shelf-stable 🔗https://phasegenomics.com/contact-us/

Join us at the Microbiome Innovation One Health Conference in Oxford on Sept 15! @ivanliachko.bsky.social will present how ProxiMeta™ maps microbes, viruses, plasmids & resistance genes, bringing clarity to complexity across human, animal and environmental health.

🧬 Important Slug News! Researchers assembled a chromosome-scale #genome for Deroceras laeve using Proximo Hi-C and @pacbio.bsky.social - making it a useful model for study of #genomics, #evolution, and slimyness... Congrats to Alfredo Varela-Echavarría & team! 🔗 academic.oup.com/g3journal/ad...

A fungus among us: Proximo Hi‑C + @pacbio.bsky.social HiFi produced telomere‑to‑telomere genomes for VCG‑01111/01112, uncovering 4 accessory chromosomes, >3.6 My divergence, SIX6 and novel effectors—pinpointing drivers of high virulence. www.mdpi.com/2309-608X/11...

Stanford researchers just achieved another 1st: Using ProxiMeta™, helped isolate p-crAssphage, a common gut virus and shape shifter that can switch between producing viruses and quietly living in bacteria like a plasmid. Read more in @cp-cellhostmicrobe.bsky.social: www.cell.com/cell-host-mi...

New study uses long-read + @phasegenomics.bsky.social Hi-C to assemble chromosome-scale #genome of Trichomonas vaginalis and bird-infecting relatives, revealing key genes tied to bird-to-human spillover. Congrats to Jane Carlton, ‪@mikeschatz.bsky.social‬ and team!

Structural variants often go undetected by traditional cytogenetics. A new review in Genes shows how Genomic Proximity Mapping™ (GPM) detects complex SVs right from FFPE. Read more Dr. Patrick Gonzales at the University of Kansas Medical Center: www.mdpi.com/2073-4425/16...

Scenes from #CGC2025: Min Fang, MD, PhD at Fred Hutch shared how Genomic Proximity Mapping™ (GPM) powers her next-gen cytogenomic analysis in AML. If you’re at #CGC2025 this year, stop by booth 23 to speak with the Phase Genomics team about how #GPM can accelerate your research!

When sample quality is low, insight usually is too. Not with Genomic Proximity Mapping™ (GPM). Phase Genomics’ GPM works on #FFPE and mosaic samples. It’s just one assay, no metaphase prep, and no tradeoff in resolution. A new preprint shows how: www.medrxiv.org/content/10.1...

Comprehensive cytogenetics from any sample type—including #FFPE—in just one assay: CytoTerra® delivers genome-wide SV detection with no culture, no HMW DNA, and results in as little as 5 days. Stop by booth 23 & check out our presentations to see it in action at #CGC2025.

A major advance in the field of human #genetics and #cancer #genomics! As always, we are proud to have been able to contribute our small part to this huge undertaking. 🧬 130 haplotypes, many T2T 🧬 Closed 92% of assembly gaps 🧬 1,852 complex SVs 🧬 1,246 centromeres www.nature.com/articles/s41...

🌸 Chromosome-scale genome of Petunia hybrida assembled with Proximo Hi-C, PacBio HiFi, Illumina & Bionano. 7 pseudochromosomes, 99.8% BUSCO with Hi-C being key for resolving repeats. A powerful resource for Solanaceae genetics & breeding. #genome #HiC 📄 hubs.la/Q03ypPmb0

Introducing PGShield™ - our new room-temperature sample solution for Hi-C. No more dry ice shipments. Improved data quality and library yields. Store your samples for months without sacrificing data quality. Get a FREE 10mL bottle today! #genomics #HiC 🔗https://hubs.la/Q03yhGWf0

🌱🧬Researchers released haplotype-resolved, chromosome-level genomes of Eupatorium splendens - a plant known for medicinal properties and ability to thrive in contaminated soils. A powerful resource for studying stress adaptation & secondary metabolism. www.nature.com/articles/s41...

🍓 Meet ‘Yuexin’ - a next-gen #strawberry with smoother texture, better shelf life, and sweeter aroma. Scientists have released its fully phased #genome, revealing the genetic secrets behind these tasty traits. Proximo #HiC + @pacbio.bsky.social for the win! 🧬 🔗 hubs.la/Q03tZvZD0

Meet the new ProxiMeta™ Starter Bundle, your all-in-one solution perfect for pilot studies and early-career researchers. It includes everything you need—from reagents to one-click data access—with success guaranteed for up to two samples. Learn more: bit.ly/4nEZMNF

“It’s not a brute force technology. It’s a clever technology.” — Jon Chee, CEO @ Excedr In the finale of The Biotech Startups Podcast, Jon and @ivanliachko.bsky.social unpack how smart science powers Phase Genomics' impact in cancer research, metagenomics & more👇 youtu.be/fqL6ZvS2sNQ?...

New💩🚰👨‍🔬 study in #EnvMicrobiology uses shotgun & Hi-C metagenomics to reveal rapid shifts in antibiotic resistance genes and their microbial hosts, highlighting the dynamic nature of resistomes. #AMR #Metagenomics 🔗https://hubs.la/Q03tZ1Jf0

TBT: 🧬 Throwing it back to a cool study from Aug 2021! Using proximity ligation, this paper explores the two-compartment genome of R. irregularis, a model arbuscular mycorrhizal symbiont, using Proximo #HiC and @nanoporetech.com sequencing. @Blunt_Microbe 🔗 Full study: hubs.la/Q03tZ6Ch0

“If we don’t commercialize this, it’s going to be a crime against science.” - @ivanliachko.bsky.social, Founder and CEO Hear how a postdoc aha moment became a platform accelerating #microbiome research, tackling #AMR & more on the Biotech Startups Podcast: www.youtube.com/watch?v=U2UG...

Unleashing the wild side of lupins! 🌕🐺🍃 Researchers built #genomes of rough-seeded lupins - L. cosentinii & L. digitatus - revealing unique #gene expansions tied to stress resilience and seed traits. A howling good resource for legume breeding! #HiC 🔗 hubs.la/Q03v1F2c0

Can’t see the full picture with karyotyping or microarrays? New research in @Genes_MDPI shows how Genomic Proximity Mapping (GPM) detects structural variants other tools miss - translocations, insertions & CN-LOH - even from FFPE! hubs.la/Q03v2s2N0 #Cancer #Cytogenetics

New pod: Tune into the convo with Phase Genomics CEO @ivanliachko.bsky.social and The Biotech Startups Podcast host Jon Chee. Hear how Ivan and the team tackle biology’s biggest problems with authentic curiosity and resourcefulness. 🔗https://youtu.be/2WCGlwVunKk?si=MBzXsDGfCqgQssDo