In this great new paper, the authors use metagenomic Hi-C to show that #phage with broad host range are fairly common, contrary to the prevailing view on their biology. Cutting edge methods like Hi-C are shedding light on our blind spots in the microbial world.

ProxiMeta™ turns your benchtop box into a Hi-C metagenomics powerhouse. Order before Sept. 30 to lock in 20% savings on the 8-sample ProxiMeta Classic Hi-C Kit, or 50% on the 2-sample ProxiMeta Starter Hi-C Kit. 🔗https://phasegenomics.com/contact-us/

Don’t let your lab’s grant dollars go to waste. Order before September 30 to save 20% on ProxiMeta™ Classic Hi-C Kit, or 50% on the ProxiMeta Starter Hi-C Kit. ✔️ Hands-off workflow ✔️ Flexible timelines ✔️ PGShield™ to keep samples shelf-stable 🔗https://phasegenomics.com/contact-us/

Join us at the Microbiome Innovation One Health Conference in Oxford on Sept 15! @ivanliachko.bsky.social will present how ProxiMeta™ maps microbes, viruses, plasmids & resistance genes, bringing clarity to complexity across human, animal and environmental health.

🧬 Important Slug News! Researchers assembled a chromosome-scale #genome for Deroceras laeve using Proximo Hi-C and @pacbio.bsky.social - making it a useful model for study of #genomics, #evolution, and slimyness... Congrats to Alfredo Varela-Echavarría & team! 🔗 academic.oup.com/g3journal/ad...

A fungus among us: Proximo Hi‑C + @pacbio.bsky.social HiFi produced telomere‑to‑telomere genomes for VCG‑01111/01112, uncovering 4 accessory chromosomes, >3.6 My divergence, SIX6 and novel effectors—pinpointing drivers of high virulence. www.mdpi.com/2309-608X/11...

Stanford researchers just achieved another 1st: Using ProxiMeta™, helped isolate p-crAssphage, a common gut virus and shape shifter that can switch between producing viruses and quietly living in bacteria like a plasmid. Read more in @cp-cellhostmicrobe.bsky.social: www.cell.com/cell-host-mi...

New study uses long-read + @phasegenomics.bsky.social Hi-C to assemble chromosome-scale #genome of Trichomonas vaginalis and bird-infecting relatives, revealing key genes tied to bird-to-human spillover. Congrats to Jane Carlton, ‪@mikeschatz.bsky.social‬ and team!

Structural variants often go undetected by traditional cytogenetics. A new review in Genes shows how Genomic Proximity Mapping™ (GPM) detects complex SVs right from FFPE. Read more Dr. Patrick Gonzales at the University of Kansas Medical Center: www.mdpi.com/2073-4425/16...

Scenes from #CGC2025: Min Fang, MD, PhD at Fred Hutch shared how Genomic Proximity Mapping™ (GPM) powers her next-gen cytogenomic analysis in AML. If you’re at #CGC2025 this year, stop by booth 23 to speak with the Phase Genomics team about how #GPM can accelerate your research!

When sample quality is low, insight usually is too. Not with Genomic Proximity Mapping™ (GPM). Phase Genomics’ GPM works on #FFPE and mosaic samples. It’s just one assay, no metaphase prep, and no tradeoff in resolution. A new preprint shows how: www.medrxiv.org/content/10.1...

Comprehensive cytogenetics from any sample type—including #FFPE—in just one assay: CytoTerra® delivers genome-wide SV detection with no culture, no HMW DNA, and results in as little as 5 days. Stop by booth 23 & check out our presentations to see it in action at #CGC2025.

A major advance in the field of human #genetics and #cancer #genomics! As always, we are proud to have been able to contribute our small part to this huge undertaking. 🧬 130 haplotypes, many T2T 🧬 Closed 92% of assembly gaps 🧬 1,852 complex SVs 🧬 1,246 centromeres www.nature.com/articles/s41...

🌸 Chromosome-scale genome of Petunia hybrida assembled with Proximo Hi-C, PacBio HiFi, Illumina & Bionano. 7 pseudochromosomes, 99.8% BUSCO with Hi-C being key for resolving repeats. A powerful resource for Solanaceae genetics & breeding. #genome #HiC 📄 hubs.la/Q03ypPmb0

Introducing PGShield™ - our new room-temperature sample solution for Hi-C. No more dry ice shipments. Improved data quality and library yields. Store your samples for months without sacrificing data quality. Get a FREE 10mL bottle today! #genomics #HiC 🔗https://hubs.la/Q03yhGWf0

🌱🧬Researchers released haplotype-resolved, chromosome-level genomes of Eupatorium splendens - a plant known for medicinal properties and ability to thrive in contaminated soils. A powerful resource for studying stress adaptation & secondary metabolism. www.nature.com/articles/s41...

🍓 Meet ‘Yuexin’ - a next-gen #strawberry with smoother texture, better shelf life, and sweeter aroma. Scientists have released its fully phased #genome, revealing the genetic secrets behind these tasty traits. Proximo #HiC + @pacbio.bsky.social for the win! 🧬 🔗 hubs.la/Q03tZvZD0

Meet the new ProxiMeta™ Starter Bundle, your all-in-one solution perfect for pilot studies and early-career researchers. It includes everything you need—from reagents to one-click data access—with success guaranteed for up to two samples. Learn more: bit.ly/4nEZMNF

“It’s not a brute force technology. It’s a clever technology.” — Jon Chee, CEO @ Excedr In the finale of The Biotech Startups Podcast, Jon and @ivanliachko.bsky.social unpack how smart science powers Phase Genomics' impact in cancer research, metagenomics & more👇 youtu.be/fqL6ZvS2sNQ?...

New💩🚰👨‍🔬 study in #EnvMicrobiology uses shotgun & Hi-C metagenomics to reveal rapid shifts in antibiotic resistance genes and their microbial hosts, highlighting the dynamic nature of resistomes. #AMR #Metagenomics 🔗https://hubs.la/Q03tZ1Jf0

TBT: 🧬 Throwing it back to a cool study from Aug 2021! Using proximity ligation, this paper explores the two-compartment genome of R. irregularis, a model arbuscular mycorrhizal symbiont, using Proximo #HiC and @nanoporetech.com sequencing. @Blunt_Microbe 🔗 Full study: hubs.la/Q03tZ6Ch0

“If we don’t commercialize this, it’s going to be a crime against science.” - @ivanliachko.bsky.social, Founder and CEO Hear how a postdoc aha moment became a platform accelerating #microbiome research, tackling #AMR & more on the Biotech Startups Podcast: www.youtube.com/watch?v=U2UG...

Unleashing the wild side of lupins! 🌕🐺🍃 Researchers built #genomes of rough-seeded lupins - L. cosentinii & L. digitatus - revealing unique #gene expansions tied to stress resilience and seed traits. A howling good resource for legume breeding! #HiC 🔗 hubs.la/Q03v1F2c0

Can’t see the full picture with karyotyping or microarrays? New research in @Genes_MDPI shows how Genomic Proximity Mapping (GPM) detects structural variants other tools miss - translocations, insertions & CN-LOH - even from FFPE! hubs.la/Q03v2s2N0 #Cancer #Cytogenetics

New pod: Tune into the convo with Phase Genomics CEO @ivanliachko.bsky.social and The Biotech Startups Podcast host Jon Chee. Hear how Ivan and the team tackle biology’s biggest problems with authentic curiosity and resourcefulness. 🔗https://youtu.be/2WCGlwVunKk?si=MBzXsDGfCqgQssDo

Phase Genomics is making Hi-C metagenomics simpler than ever with the new ProxiMeta™ Starter and Elite Bundles. These ready-to-run solutions combine sequencing, no-code bioinformatics & expert support into streamlined packages. #microbiome #phage More in @BioSpace: www.biospace.com/press-releas...

Just launched at #ASMicrobe 2025: the new ready-to-use ProxiMeta™ Starter and Elite bundles for Hi-C metagenomics. Visit booth #1109 to chat w/ the team about how the new bundles can accelerate your research, or discover more online & book a call here: info.phasegenomics.com/proximeta-bu...

Welcome Shannan Moran, Operations Coordinator! With 20 years of operational expertise from Fred Hutch & Providence, she'll help us deliver powerful proximity ligation seq & Hi-C tools to researchers worldwide, accelerating discoveries in oncology and #AMR. Welcome aboard!

ICYMI: A jam-packed spring edition of Phasebook, available in your inbox and on the web. You’ll find all the latest on our Hi-C tech and updates from the Phase Genomics team here: info.phasegenomics.com/phasebook

Catch Phase Genomics CEO @ivanliachko.bsky.social at NIAMRRE 2025 for an insightful panel discussion on #AMR in today’s shifting landscape on Thurs, May 15. Find the full details and register here: exchange.niamrre.org/2025niamrrea...

🌾 New genome study in @natcomms.nature.com uses Proximo Hi-C to help unravel wheatgrass Y haplome origin & identifies genetic keys for UV-B adaptation at high altitudes. Hi-C facilitated accurate scaffolding of this >10Gb genome. #Genomics #Genome #HiC #Wheat 🔗 Link t.co/t0Yb5q4w7U

A new reference genome for the Boat-tailed Grackle is now available, paving the way for advancing research in avian genetics and conservation. Big congratulations to Eamon Corbett, @brantfaircloth.bsky.social and team! #Genomics #Ornithology @lsu.bsky.social 🐦‍ Read more: hubs.la/Q03kB2nS0

🌿 New study in @CurrentBiology uses Proximo Hi-C to help build 8 chromosome-scale genomes of duckweed, revealing genomic & epigenomic clues behind triploid hybridization & clonal reproduction. Congrats to Robert Martienssen and team! #Genomics #Genome 🔗 hubs.la/Q03k94Kc0

New at #AACR25: Researchers used Genomic Proximity Mapping™ (GPM) to zoom in on new targets for drug discovery in #HNSCC & better biomarkers for sarcoma that standard-of-care tools missed. It’s cytogenetics without the bottlenecks. Read the full story here: phasegenomics.com/aacr-2025/

🔬Zoom into the new data at #AACR25🔬 Visit our two posters to see how Phase Genomics’ proprietary Genomic Proximity Mapping™ (GPM) tech extends cytogenetics to solid tumor cancers in a single assay, w/o the need for labor- & time-intensive reflex testing. 🔗https://info.phasegenomics.com/cytoterra

New study in @CellReports from the team at @MedicalCollege uses Proximo Hi-C to uncover how DNA folds differently in breast cancer. They help pinpoint a potential target to reverse drug resistance, shedding light on methods to improve treatment effectiveness. hubs.la/Q03jcP870 #cancer #breastcancer

🦠🐝 New preprint reveals that Mobile Genetic Elements in the honeybee gut microbiome show diverse host range patterns, influencing microbial evolution and ecology. ProxiMeta linked MGEs to their microbial hosts. #Microbiome #Bee @chicascientifica.bsky.social biorxiv.org/content/10.1...

2 weeks from today: Catch Phase Genomics’ @IvanLiachko and Steve Eacker at #AACR2025 in Chicago, April 25–30. We’ll present two posters on Genomic Proximity Mapping™ (GPM) for the genome-wide detection of chromosomal abnormalities in HNSCC & sarcoma. Find the full details:

ProxiMeta™ Explorer is your fast track to the forefront of #metagenomics #microbiome. You’ll get automated, coding-free bioinformatics and interactive visualizations. And we’re including Explorer free with our ProxiMeta kits. Try a free demo: tinyurl.com/5f3yjt8a

Move your research forward, faster. The CytoTerra® platform gives you access to comprehensive cytogenetic profiling in a single assay: ▶️ No new equipment to buy ▶️ No specialized workforce needed Learn more🔗 info.phasegenomics.com/cytoterra

The best things come in 2s—like our purpose-built, user-friendly Proximo™ Hi-C Plant Kit two-packs. Purchase a Proximo Hi-C Plant two-pack by April 30 & we’ll send you #PGShield preservative for long-term sample storage at *without* refrigeration. 🛒 bit.ly/4iLCuCy

Developed by scientists, for scientists: our user-friendly Proximo™ Hi-C Plant Kits support a wide range of genomic research applications, backed by expert support. We’re here when you need us with industry-leading response times—because we’ve been there before. 🔗https://bit.ly/4iLCuCy

Phase Genomics’ Proximo™ Hi-C tech took plant genomics platinum. Now, Proximo has helped drive plant genomic discovery in more than 200 journal articles. [1/3]

Tune in to the Talk is Biotech podcast to hear Phase Genomics CEO @ivanliachko.bsky.social share how Hi-C unlocks new DNA discoveries: “It’s a sequence of letters, but it makes shapes, colors—it makes a strawberry look like a strawberry.” Thanks to pod host Guru Singh: bit.ly/4ijpyUy

Biology is complex. Your go-to Hi-C protocol shouldn’t be. Our Proximo™ Hi-C kits take just 3 hours of hands-on time & 8 steps for library prep. And it can all be sequenced on ubiquitous NGS platforms. Explore Proximo Hi-C for haplotype-resolved, chromosome-scale insights: bit.ly/4kaBf1c

Today on the International Day of Women & Girls in Science—and every day—we honor the women who drive discovery forward. From the double helix to WiFi, we celebrate their discoveries that define modern life. Because women shape every second of science, every day of the year.

Proximo™ Hi-C helped researchers in 🇦🇺 pinpoint new oat crown rust #plantpathogen. They used our Hi-C tech to pinpoint new somatic hybridization & intercontinental movement of haplotypes, a major step toward a #pangenome & int’l molecular-level monitoring. More: journals.plos.org/plosgenetics...

Take a look at how Genomic Proximity Mapping™ (GPM) accelerates your discovery. We’ll build your new map of the genome to help you build the future of #cancerbiology. GPM pinpoints known & novel chromosomal anomalies in cell lines, blood—and even #FFPE samples. Here’s how:

Peas are packed with protein—but for an unlucky few, one of those proteins is an allergen. Researchers used our Proximo Hi-C protocol to build the genome for future breeding studies. Because the only place peas should pack a punch is in nutrition. More in @jxbotany.bsky.social: bit.ly/3E1g4OD

Using our Hi-C kits and @pacbio.bsky.social, researchers at ICAR assembled a #chromosome -level #genome of a near-threatened freshwater catfish, providing valuable resources for comparative genomics and the enhancement of economic traits in aquaculture. Read here: www.nature.com/articles/s41...