Countdown to #GAMRIC2025: The inaugural Global AMR Innovators Conference kicks off tomorrow in London! Join CARB-X and global leaders as we dive into discussions about #AMR policy and antimicrobial research and development. #GlobalHealth #CARBX #IDSky 🧪

My new review article covers key points I have not seen in any other review of cancer immunotherapy: i) the difference between IFN-a and IFN-b; ii) the unique role of P1 pDC among all DC subsets; iii) the unique role of TLR7/8/9 among TLRs nam10.safelinks.protection.outlook.com?url=http%3A%...

Happy to share the most recent preprint from the lab, the thesis work of Dr. Adam Krebs and a collaboration with many, including the Geissmann lab @mskcancercenter.bsky.social Here is a short paper thread. #tuberculosis #macrophages 🦠 www.biorxiv.org/content/10.1...

We are on the lookout for postdocs for two different projects at the intersection of ecology, evolution, and the human microbiome. See thread for more information and reach out!

There is only one way to end the war: put pressure on the Russians. The Trump people did the opposite: put pressure on Ukraine, and relieved pressure on Russia. They have made the war worse while talking of "peace."

Merci, EmmanuelMacron 💙💛 Every European will be safer if every part of Ukraine is sovereign and pro-European. russian occupation of an independent country creates a precedent that endangers the entire continent.

A lot of what looks like microbial engraftment after FMT might actually be noise. Using placebo sequencing and culture-enriched metagenomics, we sort signal from noise. Our latest from the Surette lab: www.nature.com/articles/s41... @surettem.bsky.social @mcmasteruniversity.bsky.social

Sign of the day…Chicago

looking forward to #ESCMIDGlobal next week in Vienna. I'd love to connect and discuss developing microbiome drugs to prevent infection. Come to the Innovation Theater 12 April at 11:30!

I have a trade deficit with Trader Joe's, who are so unfair because they never buy anything back from me, so I will have to impose some tariffs.

I can feel the pain in this summary at the end of the day. A lot of people trying to collect themselves. More pain to come. Will need to strengthen our common ties to advance the public health and individual medical outcomes. yourlocalepidemiologist.substack.com/p/why-we-kee...

From an operational security perspective, this is the highest level of fuckup imaginable. These people cannot keep America safe.

How Beethoven could come up with this absolute marvel when he was dealing with hearing loss is beyond my comprehension. It's like he found a secret shortcut to reach the soul. youtu.be/ESilvOS2O9k

Our gut microbiome and its metabolites have key interactions with our immune response to cancer and success from cancer immunotherapy. Nice perspective @jclinical-invest.bsky.social www.jci.org/articles/vie...

I hope the new administration can appreciate that basic research in infectious diseases is also a matter of national security, which we all care about no matter who we vote for www.propublica.org/article/nih-...

Well, I went back to see if the birds came out again yesterday. And it was even more stunning. At first, it seemed like little was going on & then my brother Matt, who came out with/ me to record sound (he's a sound engineer) told us to look up. #birds youtu.be/r_1OX3LVK1g

Assessing Live Microbial Therapeutic Transmission, from Jay Faith www.tandfonline.com/doi/full/10....

Today our team published additional results from the Phase 2 CONSORTIUM study for our lead candidate, VE303, a potential first-in-class Live Biotherapeutic Product which is being evaluated for prevention of recurrent Clostridioides difficile infection (rCDI). full-text access: rdcu.be/d5ovX

My parents' work today:

(1/5) Traditionally, antibiotic discovery has centered on bacteria and fungi—until now. For the first time, we present a systematic exploration of Archaea—a major yet underexplored branch of the tree of life—as a source of novel antimicrobial compounds. www.biorxiv.org/content/10.1...

On the definition of Live Biotherapeutic Product. Online today @jidjournal.bsky.social academic.oup.com/jid/advance-...

One of my favorite visualizations, showing the sizes of host and microbial cells on the same scale, spanning several orders of magnitude From a review by Baker et al : pubmed.ncbi.nlm.nih.gov/37700024/

Denali National Park In Alaska, USA

This work led by Jay Faith's lab at Mount Sinai maps the number of unique strains of a species that can stably colonize the human intestine for the most common human commensals. A useful guide for design of Live Biotherapeutic Products www.nature.com/articles/s41...

Concerning, coming from someone who understands very well the system www.cnbc.com/video/2024/1...

JOB CLAXON! I am recruiting a post-doctoral researcher on a BBSRC-funded project (36 months) on the genetics and functional genomics of vancomycin resistance in enterococci. Further details here: edzz.fa.em3.oraclecloud.com/hcmUI/Candid... Please DM or email me if you want to discuss this post.

Consider co-signing, if you agree, this letter to the California Congressional Delegation asking them to weigh in U.S. House and Senate leadership to pass the PASTEUR Act by the end of the year. www.fightinfectiousdisease.org/post/sign-on...

For my inaugural post, I’m sharing this recent talk on the immune considerations in mRNA therapeutics. Optimizing CD8+ T cell responses requires understanding the biology of IFN-a/b, which has been ignored in recent cancer immunotherapy review articles. youtu.be/Isz5FqRpqbM

Hello world. I'm a researcher at Vedanta Biosciences where we are developing defined bacterial consortia to modulate the microbiome and treat or prevent human disease. General focus areas: microbial ecology, drug discovery, IBD and infectious disease. Wordcloud via scholargoggler.com

For @asm.org Microbe June 19-23 2025, I am organizing a special session on manufacturing of Fecal Microbiota Products and Defined Bacterial Consortia. Please consider submitting an abstract and share with others working in this area! asm.org/Events/ASM-M...

Has FDA approved any Live Biotherapeutic Products? A: Yes, 2 B: No Are products prepared from human stool LBPs? A: Yes B: No This letter to the editor of @JIDJournal, with Cliff McDonald at CDC and Ryan Ranallo at NIAID seeks clarity on nomenclature academic.oup.com/jid/advance-...

A proud day today for the Vedanta Biosciences family, as Adam Krebs is just finishing his thesis defense presentation, soon to become our first alum to go on to complete a PhD! Adam did his thesis with @michaelglickman.bsky.social at MSKCC working on tuberculosis.